Ursus maritimus (polar bear): 103673381 Help Entry 103673381         CDS       T03271                                  Symbol SPG11 Name (RefSeq) spatacsin   KO K19026   spatacsin Organism umr  Ursus maritimus (polar bear) Pathway umr04142   Lysosome umr05014   Amyotrophic lateral sclerosis umr05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:umr00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     103673381 (SPG11)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     103673381 (SPG11)    05022 Pathways of neurodegeneration - multiple diseases     103673381 (SPG11)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:umr03400]     103673381 (SPG11) DNA repair and recombination proteins [BR:umr03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      103673381 (SPG11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spatacsin_C Motif Other DBs NCBI-GeneID:  103673381 NCBI-ProteinID:  XP_008700361 UniProt:  A0A384D007 LinkDB All DBs Position Unknown AA seq 2445 aa AA seqDB search MAAEKAAGGAAGLGACSAKAMERVLPMLLVPVPVEATGRLGSRAQLHREQEVLGSLTAAG SLQVLSLAPGGRSGGTCCLGGPFRHFVWEDSHISSSPTDKPKLLALSENYELFIYEFNLK DGRCDATILYSCSEETLQKLIEDQNISVSLLSLKLLSFRNNKSLLFINKCIVLHIVFPER GAEIEVLNCFTLPLPAQAVDRIIDTQLCRGILFALNSLGWIYIFDVVDGTHVAHVDLALH QEDMYGERQQEPAKISSFTSLKVSQDLDVVVIVGSSSSAIALNLNLYFRQHPGHLLCERT QEDIPIEGPKGIDEDDPVNSDYNMKLTKFSFQVDRSWKAQLVSLNETIKSSKLEVSYCAP WFQNISHLESPESGNHSTSMPGWAFIPQDVMHSHSKFPQKDHANTSEPGRSWKIMNISEQ EEPVELTCMSVTGFSALFTWAVERTGCTIGLWDLETQGMQCFSLGKKCIPIETSGDQQLC LVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENHQ LDTVDFFLKSKENLLNLSSKSSIPDQLDDFPSHLYLRNVEKLTPALDLLCSAIRESDSET QSKHFSEQLLNLTLSFLNKQIKELFVHNEELDEHLQKGVNILTSYINELRTFMIKFPWKI IDTVDEYDVNENVPKVRESNIWEKLSVEEVIANAILNNKIPEAQTFFRINNHSAQRLEEL IRIGLNLVFDSLKKNNIKEASELLKNMGFDVKDQLLKICFYTTETNIRDFLVEILKEKNY FSENEKRTIDFVHQVEKFYSGRFQENVQIQSFARCWIKEQDFFKHKSVLDSLLKYDPKDK FNKQDRRVVLNWAQWWNQLTQESILLPRISPEEYKSYSPEALWSYLTARHDWSSIILWIG EFQTQNSCASLQQNRWPLLTTDVIDRHTCCNNYMRNEILDQLARNGIFLNSELEDFELFL LRLNRIGGVMQDALPIQNYRSKEGWDFHSHFILYCLEHGLQYLLYVYLDCYKLSPSNCPF LEKKELYEAYPWFEFLVQCRQVSSNLTDPKLIFQASLANAQILIPSNQASVSSMLLEGHT LLALATTMYAPGGVSQVVQNGENETCLKKVDPQLLKMALTPYPKLKTALFPQYTASNVLP PDITLYHLIQSLLPFDPSRLFGWQSANTLAIGDAGSHLPHFSSPDLVNKYAIVERLNFAY YLQHGRPSFAFGTFLVQELTKSKTPKQLIQQAGNEAYVLGLSSFYIPSVAAACVCFLELL GLDSLKLRVDMKVANIILSYKCRKEDAQYSCIRESLAEKLSKLAVGEKATIEELLVLLEE GIWNSIQQQEMKRVSSESSSQWALAVQFCRLHNVKLSTSYLKECAKANDWLQFIIHSQLH NYHPEEVKSLLQYFSPVLQDHLRLAFENLTSVSNSRMDSDQVFNRAPQELQRNKEEMTDF FEVLLQCSEEPNSWCWLLAEAVKQQAPILSVLASCLQDASTVPCLCVWIITSVEDSVTAE ATEHIQGSMEGHVWDLQDLAVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLMMEMYELCMF FKNYKEAEAKLLEFQKSFETVETAATRVHTATIPAPWLKEQVCFLLKLMLRQCGTQYELG KLLQLFVGIEDLFSDGPDVKKLCVLSQILKDTSIAINHAIITSYSLENFQHECKYILEKL ETAGQFALARRVAELAELPADSLVIEEVTQEMQTLKHIDQWSLKQARIDFWKKCHENFKK NAISSRAASSFFSAQAGEVPEPPAEGGRSGVGERQLLLALAAHWLAQEDLGPVDELEELE KQIWLCRIAQHTLREKQEETEPGFSPHVSTSGELSFDSVASKFSLSMLAALNTSKYLELN GLPSRETCEDRLDGKEQESLNFLIGRLLDDGCVHEASRVCRYFRFYNQDVALVLHCRALA SGEASVDELHPEIHALLQGAERLEEEEPGIPLRKVQSASSLDSQSFVMLPPSDEVVTNLE TLTSRCLHGKNYCRQVLCLYELAKELGCSYTDVAAQDGEAMLRAILASQQPDRCKRAQAF ISTQGLEPDTVAELVAEEVTRELLTPSEGTGQKQMFTPAEESQTFLQLTTLCQDRTLVGM KLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAARLLTDKHLAPSEEYGL MVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKH NMIALCFSMCREIGENHEAAACIQLKLIESQPWEDSLKDGHHLKQLLLKALTLMLDAAES YAKDSCVRQALHCHRLTKLITLQIHFLNTGQNTMIINLGRHRLMDCLIALPRFYQASIVA EAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLRSSIFEEISKKYKQHQPADTVVKNL KKLLTYCEDVYLYYKLAYEHKFYDIVNVLLKDPQTGCCLKDMLAG NT seq 7338 nt NT seq  +upstreamnt  +downstreamnt atggctgcagaaaaggcagcggggggagctgctggcctcggcgcctgtagcgctaaagcc atggagcgggttctacctatgctgttggtgccggtccctgtggaggcaacggggcggctg ggatcccgggcgcagttgcacagagagcaggaggttctggggagcctaacagctgcaggc agcctgcaagtgctttccttggcgccgggcggccggagcgggggtacctgctgcctcggt ggcccttttcggcacttcgtatgggaggattctcatatcagcagctcaccaacagacaag cccaaactgcttgctcttagtgaaaattatgaactgtttatctatgaatttaatttgaaa gatggaagatgtgatgcaaccattttgtatagctgtagcgaggagaccttgcaaaagctc attgaagatcaaaatattagtgtttccttattatctttgaaacttctgtcatttcgcaat aacaagtcactgttgttcatcaacaaatgtattgtcctacacattgtatttcctgaaaga ggtgctgagatagaagttctcaactgtttcacattacccttgcctgcacaggcagtggac aggattattgacacgcagctctgccgaggaattctttttgctttgaatagtttaggctgg atctacatttttgacgttgtggatggtacacatgtagctcacgtggatttagcacttcac caagaagacatgtatggtgagcggcagcaggagccagccaagatttcttcctttacttca ctgaaagtgtctcaggacctagatgttgtagtgattgtcggctcctccagctctgcaatt gctcttaacttaaacttgtatttcaggcaacacccaggacacctactgtgtgaaagaact caagaagacattcctattgaaggccctaagggcatagatgaagatgatcctgttaattct gactacaacatgaaactgaccaagttttcctttcaagttgataggtcttggaaagcccag ctagtatcattgaatgaaacaataaagagctccaaactggaggtttcctattgtgctcca tggttccagaatatttcacatttggaatcccctgaatctggtaaccacagtaccagtatg ccaggctgggcctttattccacaggacgtaatgcacagccactctaagtttccacagaag gatcatgccaacacgagtgaaccagggagatcgtggaaaataatgaacattagtgaacaa gaggaacctgttgagcttacatgtatgtctgtgacaggattcagtgcactgtttacttgg gcagtggaaaggacgggctgcaccattggcctctgggatttggagacccagggtatgcag tgtttctcccttggcaaaaagtgtattcctatagaaactagtggagaccagcagctgtgc cttgttttgacagaaaatggactctctctgattttgtttggattgactcaggaggagttt ttaaatagactaatgatccatggaagtgccagcactgtggactctctttgccatctcaat ggttgggggaggtgctcaatccccatacatgcactggaggctgggatagaaaatcatcag ctggacacagtagatttctttttgaagagcaaagaaaatcttttgaatctgtcctcaaaa tcttccatacctgatcagcttgatgactttccatctcatttgtatttaagaaatgtggaa aagcttacaccagcgttggatttactttgctcagcaatcagagaaagtgattctgaaacc cagagcaaacacttttcagaacagttgcttaatcttacactgtcttttcttaacaaacaa ataaaggaactttttgttcacaatgaagaactagatgaacatctacagaagggagtgaat attttgaccagctacattaacgaacttcgaaccttcatgataaagtttccgtggaagata atagatacagtagatgaatatgatgtaaatgaaaatgttcccaaagtaagagagagcaat atatgggagaaactcagcgttgaggaagttattgccaatgctattttaaacaacaaaata ccagaggcacagactttcttcaggattaacaatcattctgctcaaagacttgaggagctg attagaataggcctgaatttggtatttgacagtttgaaaaagaacaatataaaggaagcc tctgaacttttgaagaacatgggctttgatgtaaaagaccagttgctcaagatatgcttc tatacaactgagacaaacatacgggactttttggttgaaattttaaaagaaaaaaattat ttttctgaaaatgaaaaaagaactatagacttcgtgcatcaagttgagaagttttattca ggacgtttccaagaaaatgtgcagatccagtcctttgccaggtgttggataaaggaacag gattttttcaagcacaaatctgttttggactcactcctgaaatatgatcctaaagataaa tttaacaaacaggaccgtagagttgtgttaaattgggctcagtggtggaatcaactaaca caagagtccatccttctccccaggataagtccagaagaatacaaatcgtattctcctgaa gccctctggagctatcttacagctcgccatgactggtcaagcattatcttgtggattgga gaatttcagactcagaacagttgtgcttcgcttcaacagaacagatggccccttctgacc actgatgttatcgatcggcatacttgctgcaacaactatatgaggaatgaaattttagat cagctggccaggaatgggatttttcttaactctgaactagaagactttgaactcttcctg ctaagactgaaccgcattgggggtgtgatgcaagatgctctccccattcaaaactacaga tccaaagaaggttgggatttccattctcacttcattctctattgtttggaacacggtctg cagtatcttctctatgtctatcttgactgttacaaacttagtccttcaaattgtcccttt ttggaaaaaaaagaattatatgaagcttacccttggtttgaatttttagttcagtgtcga caagtttccagtaatttaacagatcccaaactgatcttccaggctagccttgcaaatgct cagatactgatccccagcaaccaggccagtgtaagcagtatgctattggaaggacatact ctcctggcccttgctaccacaatgtatgcccctggaggtgtcagccaggttgttcaaaat ggcgaaaatgagacctgtttgaagaaagtagatccccagttactgaagatggcattaact ccttatcccaagctaaaaactgctctcttcccacagtacactgcctctaatgttctgcca cctgatattacgctttaccaccttattcagtcactgttgccctttgaccctagtagattg tttggctggcagtctgccaacacactggctataggagacgcagggagtcatctcccacat ttttctagccctgacctggttaataaatatgctatagtagaacgtctgaattttgcatat tacttacaacatggacggccatcatttgcatttggtacttttctggtccaggaattaacc aagagcaagactcccaagcagctgatccagcaagcaggcaacgaagcctatgttttaggg ctctcctccttctacataccttcagtagcagctgcctgtgtttgtttcttagaactgctt ggcctcgacagcctcaagctcagagttgatatgaaagtggccaatataattttgagctac aagtgtagaaaggaagatgctcagtacagctgtatcagagagtctctagctgaaaaacta tctaaactggctgtgggtgaaaaggccaccatagaggaattgcttgttctcttagaagaa ggtatatggaacagcattcagcagcaggaaatgaagagggtatctagtgaatctagcagc cagtgggcattagcagtacagttctgcaggcttcataatgtgaaactgagcacgtcttac ctcaaagaatgtgccaaagcaaatgactggctacagttcattattcacagccaactccac aactatcacccagaggaggtgaaatctcttcttcagtatttcagtcctgtccttcaagac cacttaagactggcttttgagaacttgacctcagtgtctaactccagaatggacagtgat caagtcttcaacagagccccccaggaattgcagagaaacaaagaagagatgactgatttc tttgaagttctgctccagtgctcagaggagccaaactcctggtgctggctccttgctgaa gcagtgaaacaacaagcccctatccttagtgtcctggcctcatgtctccaggatgccagt actgttccttgtctctgtgtgtggatcatcacatctgtggaggacagtgttacagctgaa gcaacagagcacattcagggctcaatggaaggccacgtgtgggaccttcaagacctcgca gtcatctggagaacattattaacaaggcagaagagcaaaactctcatcagaggtttccaa cttttctttaaggattccccactactgttgatgatggagatgtacgaactgtgtatgttc ttcaagaattataaggaagctgaagctaaacttctggagttccaaaagagctttgaaact gttgaaacagcagccacgagggtccacactgctaccatccctgccccgtggctgaaggag caggtgtgttttcttctgaagcttatgctgcggcagtgtgggacccagtatgaactgggg aagcttttacagctcttcgttggaatagaagatctcttctctgatggtccagatgtgaag aagctctgtgtccttagccaaattttaaaggacacgtccatagccattaatcatgcaatt attaccagctacagccttgaaaattttcagcatgaatgtaaatatattttggaaaaactg gagacagcgggacagtttgctttggccagaagagtagcagaattagcagaactacccgct gacagcttggttattgaagaggtaacacaggaaatgcagaccttaaaacacattgaccag tggtccctgaaacaagcaagaattgacttctggaaaaaatgtcatgagaattttaagaaa aatgccatttcaagcagagcagcttcttcctttttctcagctcaggccggggaggtgcca gagcccccagctgaggggggccggagcggcgtcggggagcgccagctgctgctcgcactg gcggcgcactggcttgctcaggaggacctggggcctgtggacgaactggaggagctggag aagcagatctggctctgccgcatcgcccagcacaccctcagagaaaagcaggaggaaaca gagcccgggttttctccacacgtctcgactagtggggaactttcctttgatagcgtagcc agtaagttttcactctccatgttggctgctctgaacacatccaaatacttagaacttaat ggccttccatccagagagacttgtgaggacagactggatgggaaggagcaggagtcgctg aactttctgattgggcgcctattggatgacggctgtgtgcacgaagcaagtagggtatgt cggtattttcgtttctataaccaagatgtcgccttggttttgcactgccgagcactggcc tcaggggaagctagtgtggatgagctgcacccagagatccatgctctcctgcaaggtgct gagcggcttgaggaagaagaacctggcattccactcaggaaagtgcagagcgcttcaagt ttggatagtcagtcatttgtgatgctgccccccagtgatgaagtggtgactaatctggaa actctgacgagcagatgccttcatgggaagaactactgccgacaggtcctgtgtctgtat gaacttgccaaggagttgggctgttcctacacagacgtggctgctcaggatggtgaggcc atgctccgggcaatcttggcctctcagcagcccgatcgatgcaagcgcgcccaggctttc atcagcacccagggcctcgagccagacacggtggctgaacttgtggctgaagaggtgacc cgggagctgctgaccccatcagagggaacaggacagaagcagatgttcaccccagcagag gaaagccagacatttcttcagttgactactctgtgtcaagaccgcacgttggtaggcatg aagttgttggacaagatttcctccgttccccacggggaactgtcttgcaccacggagctg ctgatcctggcccatcactgcttcacgctgacatgccacatggagggcatcatccgagtc ctgcaagctgcccgactgctcacggacaaacacttggcccccagtgaggagtacgggctg atggtgcgcctcctgaccggcatcggaaggtacaacgagatgacctacatatttgacttg ctgcataagaagcactactttgaagtgctgatgaggaagaagctggatccgagcggcacc ctgaagacggccctcctggactacatcaaacgctgccgccccggggacagcgagaagcac aacatgattgctctgtgcttcagcatgtgtcgggagatcggggagaaccacgaggcagct gcctgcatccagctgaaactgatcgagtctcagccctgggaggacagtctcaaggacggg caccatctgaagcagctgctgctgaaagccctgactctcatgctggatgcagcggagagt tatgccaaggactcgtgtgtgagacaggccctgcactgtcaccggctcaccaagttgata acactgcagattcactttctgaacacgggccagaacacgatgatcatcaacctgggccgc caccggctcatggactgtctcatcgctctacctcggttctaccaggcttctattgtggcc gaggcctatgactttgttcctgattgggcggaaatcctctaccaacaagtgattcttaaa ggagactttaattacctggaagaatttaagcagcaaaggttattaagatctagtatattt gaagagatttccaaaaaatataaacaacaccagccggctgacacagttgtgaaaaacctg aagaagttactcacatactgtgaagatgtctacttgtattacaagctcgcgtatgaacac aaattttatgacattgtaaacgtgctgctgaaggaccctcagactggctgctgtctgaag gacatgctagcaggttag

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