Ursus maritimus (polar bear): 103674159 Help Entry 103674159         CDS       T03271                                  Symbol EP300 Name (RefSeq) histone acetyltransferase p300   KO K04498   E1A/CREB-binding protein [EC:2.3.1.48] Organism umr  Ursus maritimus (polar bear) Pathway umr03083   Polycomb repressive complex umr03250   Viral life cycle - HIV-1 umr04024   cAMP signaling pathway umr04066   HIF-1 signaling pathway umr04068   FoxO signaling pathway umr04110   Cell cycle umr04310   Wnt signaling pathway umr04330   Notch signaling pathway umr04350   TGF-beta signaling pathway umr04520   Adherens junction umr04630   JAK-STAT signaling pathway umr04720   Long-term potentiation umr04916   Melanogenesis umr04919   Thyroid hormone signaling pathway umr04922   Glucagon signaling pathway umr04935   Growth hormone synthesis, secretion and action umr05016   Huntington disease umr05152   Tuberculosis umr05161   Hepatitis B umr05164   Influenza A umr05165   Human papillomavirus infection umr05166   Human T-cell leukemia virus 1 infection umr05167   Kaposi sarcoma-associated herpesvirus infection umr05200   Pathways in cancer umr05203   Viral carcinogenesis umr05206   MicroRNAs in cancer umr05211   Renal cell carcinoma umr05215   Prostate cancer Brite KEGG Orthology (KO) [BR:umr00001]  09120 Genetic Information Processing   09126 Chromosome    03083 Polycomb repressive complex     103674159 (EP300)   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     103674159 (EP300)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     103674159 (EP300)    04330 Notch signaling pathway     103674159 (EP300)    04350 TGF-beta signaling pathway     103674159 (EP300)    04630 JAK-STAT signaling pathway     103674159 (EP300)    04066 HIF-1 signaling pathway     103674159 (EP300)    04068 FoxO signaling pathway     103674159 (EP300)    04024 cAMP signaling pathway     103674159 (EP300)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103674159 (EP300)   09144 Cellular community - eukaryotes    04520 Adherens junction     103674159 (EP300)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     103674159 (EP300)    04935 Growth hormone synthesis, secretion and action     103674159 (EP300)    04919 Thyroid hormone signaling pathway     103674159 (EP300)    04916 Melanogenesis     103674159 (EP300)   09156 Nervous system    04720 Long-term potentiation     103674159 (EP300)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103674159 (EP300)    05206 MicroRNAs in cancer     103674159 (EP300)    05203 Viral carcinogenesis     103674159 (EP300)   09162 Cancer: specific types    05211 Renal cell carcinoma     103674159 (EP300)    05215 Prostate cancer     103674159 (EP300)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103674159 (EP300)    05161 Hepatitis B     103674159 (EP300)    05164 Influenza A     103674159 (EP300)    05167 Kaposi sarcoma-associated herpesvirus infection     103674159 (EP300)    05165 Human papillomavirus infection     103674159 (EP300)   09171 Infectious disease: bacterial    05152 Tuberculosis     103674159 (EP300)   09164 Neurodegenerative disease    05016 Huntington disease     103674159 (EP300)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:umr03000]     103674159 (EP300)    03036 Chromosome and associated proteins [BR:umr03036]     103674159 (EP300)    03029 Mitochondrial biogenesis [BR:umr03029]     103674159 (EP300) Enzymes [BR:umr01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      103674159 (EP300) Transcription factors [BR:umr03000]  Eukaryotic type   Other transcription factors    Pocket domain CBP     103674159 (EP300) Chromosome and associated proteins [BR:umr03036]  Eukaryotic type   Histone modification proteins    HATs (histone acetyltransferases)     103674159 (EP300) Mitochondrial biogenesis [BR:umr03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Coactivators     103674159 (EP300) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HAT_KAT11 KIX Creb_binding zf-TAZ RING_CBP-p300 PHD_P300 Bromodomain ZZ KIX_2 Npa1 Med15_N Motif Other DBs NCBI-GeneID:  103674159 NCBI-ProteinID:  XP_040493525 UniProt:  A0A8M1GF51 LinkDB All DBs Position Unknown AA seq 2419 aa AA seqDB search MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQGMASQPQQNSPGLGLINS MVKSPMAQAGLTSPNMGMGTSGPNQGPTPSAAGMMNSPVNQPAMGMNTGMNAGMNPGMLN AGNGQGMMPNQVMNGSIGAGRGRPNMQYPNPGMGNAGNLMTEPLQQGSPQMGGQTGLRGP QPLKMGMMNNPNPYGSPYTQNSGQQIGAGGLGLQIQTKSVLPNNLSPFAMDKKAVPGGGM PNMGQQQAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN AGDKRNQQSILTGAPVGLGNTSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ MPTQPQVQAKNQQNQQSGQSPQGMRPMSNMSASPMGVNGGVGVQTSNLLSDSMLHSAINS QNPMMSENASVASLGPMPTAAQPSNTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP SAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQPGLNQFGQMS MPQPPIGPRQTSPLQHHGQLAQPGTLNPPMGYGPRMQQPSSQSQFLPQTQFSTQGMNVTN MPLAPSGGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPPLPQSALHQNSPSPVPSRT PTPHHTPPSIGAQQPPATAIPAPVPTPPAMPPGPQTQALHPPPRQTPTPPPTQLPPQVQP SLPAAPSADQPPQQPLSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS TEVNSQTIPEKQPSQEVKMEAKMEVDPPEPADAQPEDIPETKAEDCKMEPTETEERGTEL KTETKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPV DPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVY KYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYH FCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICV LHHEIIWPSGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESG EVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQ EYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACP PSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAK ELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKN KSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLI PCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET RWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNSQQAAATQSPGDSRRLSIQRCI QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN KCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPT GQQPATPQTPQPQPPSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPP LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPQMTPMAPMGMNPPPMTRGPS GHLEPGMGPTGMQQQPQWVQGGLPQPQQLQPGMPRPAMMSVAQHGQPLNIAPQPGLGQVG VSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYASSNP QPLAGQPGMPQGQPGLQPPAMPGQQGVHSSPAMPNMSPMQAGVQRAGLPQQQPQQPLQPP MGGMSPQAQQMNMNHNAMPSQFRDILRRQQMMQQQQQGAGPGIGPGMANHNQFQQPQGVG YPPPPQPQQQRMQHHLQQMQPGSMGQMGQLPQALGAEAGAGLQAYQQRLLQQQMGSPAQP NPMSPQQHMLPSQAQSPHLQGQQIPSSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQP SPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQSSMLSQLASNPGMANLHGAGATDLGL GPDNADLNSNLSQSTLDIH NT seq 7260 nt NT seq  +upstreamnt  +downstreamnt atggccgagaatgtggtggaaccggggccgccttcagccaagcggcctaaactctcatct ccggccctctcggcgtcggccagcgatggcacagattttggctctctatttgatttggag catgacttaccagatgaattaatcaactctacagaattgggactaaccaatggtggtgat attagtcagcttcagacaagtcttggcatagtacaagatgcagcctctaaacataaacag ctgtcagagttgctacggtctggtagttcccctaacctcaatatgggggttggtggccca ggccaaggcatggccagccagccccaacagaacagtcctggattaggtttgataaatagc atggttaaaagcccaatggcacaggcaggcttgacttctcccaacatggggatgggcacc agtggaccaaatcaaggtcctacgccatctgcagcaggtatgatgaacagtccagtaaat cagcctgccatgggaatgaacacagggatgaatgctggcatgaatcctggaatgttgaat gcaggcaatggacaggggatgatgcctaatcaagtcatgaacggttcaattggagcaggc cgggggcgacccaatatgcagtacccaaacccaggcatgggaaatgctggcaatttaatg accgagccactgcagcaaggctctcctcagatgggaggacaaacgggattgagaggccct cagcctcttaagatgggaatgatgaacaaccctaatccttacggttcaccatacactcag aattctggacagcagattggagccggtggccttggtctccagattcagacaaagtctgta ctaccaaataacttatctccatttgcaatggacaaaaaggcagttcctggtggaggaatg cccaacatgggtcaacagcaggccccacaagtccagcagccaggccttgtgactccagtg gcccaagggatgggttctggagcacatacagctgatccagagaagcgcaagctcatccag cagcagcttgttcttcttttacatgctcataagtgccagcgccgggagcaggctaatggg gaagtgaggcagtgcaaccttccccactgtcgcacaatgaagaacgtcctaaaccacatg acacactgccagtcaggcaagtcctgccaagtggcacactgtgcatcttctcgacaaatc atttcacactggaagaattgtacaaggcatgattgtcctgtgtgtctcccccttaaaaat gctggagataagagaaatcagcagtcaattctgactggagcaccagttggacttggaaat actagctctctaggtgtgggtcaacagtctacccctagcctaagcactgttagtcagatt gatcccagctctatagaaagggcctatgcagctcttggtctgccctatcaagtaaatcag atgccgacgcagccccaggtacaagcaaagaaccagcagaatcagcagtctgggcagtct ccccaaggcatgcggcccatgagcaacatgagtgctagtcctatgggagtaaatggaggt gtaggggttcaaacgtcaaatcttctttctgactcaatgttgcattcagccataaattct caaaacccaatgatgagtgaaaatgccagtgtggcctccctgggtcctatgccaacagca gctcaaccatccaatactggaattcggaaacaatggcatgaagatattactcaggatctt cgaaatcatcttgttcacaaacttgttcaagccatatttcctactccggatcctgctgct ttaaaagacagacgaatggaaaacttagttgcatatgcccggaaagtggaaggggacatg tatgaatctgcaaataatcgagcggaatactaccacttgctagctgagaagatctataag atccagaaagaactagaagaaaaacgaaggactagactacagaaacaaaacatgctgccc agtgctgcaggcatggtgccagtttctatgaatccagggcccaatatggggcagccacaa ccaggaatgacttccaatggccctctacctgacccatctatgatccgcggcagtgtgcca aaccagatgatgcctcggataactccacagcctggtttgaatcagtttggccagatgagt atgccccagcccccaattggaccccggcaaacctctcctcttcagcaccatggacagtta gctcagcctggaactctcaacccgcctatgggctatgggcctcgcatgcagcagccttcc agccagagccagttccttccccagactcagttctcaacacagggaatgaatgtaacgaat atgcctttggctccgtctggcggtcaagcaccagtgtctcaagcacaaatgtccagttct tcctgcccagtgaactctcctataatgcctccagggtcgcaagggagccacattcactgt ccccctctccctcaatcagctctgcatcagaattcaccctctccggtacctagtcgcacc cctacacctcaccacactcccccaagcataggggctcagcagccaccagcaacagcaatt ccagcccctgttcctacacctccagccatgccccccgggccgcagacccaggctctacat ccacctccaaggcagacacccacaccaccaccaacgcagcttcctcctcaagttcagcct tcacttcctgctgctccttcggctgaccagccaccgcagcagcctctctcacagcagagc accgcagcatctgttcccaccccaacggcgccgctgctgcccccacagcctgcgactcca ctttcccaaccagctgtaagcattgaaggtcaggtatcaaatcctccatccactagtagc acagaagtgaattctcagaccattcctgagaagcagccgtcacaggaagtgaaaatggag gcaaagatggaagtggatccaccagaaccagcagatgctcagccagaggatattccagag actaaagcagaagactgtaaaatggaacctacagaaacagaagagagaggcactgaatta aaaactgaaacaaaagaggaggaagaccagccaagtacttcagctacacagtcatctcca gccccgggacagtcaaagaagaagattttcaaaccagaagagttacgacaggcactgatg ccaactttggaggcactttaccgacaggatccggaatccctaccctttcgtcaacctgtg gaccctcaacttctaggaatccctgattattttgatattgtgaagagccccatggacctt tctaccatcaagaggaagttagacactggacagtatcaggagccctggcagtatgtggat gacatttggcttatgttcaacaatgcctggttgtataatcggaaaacatctcgggtatac aaatactgctccaagctgtctgaagtctttgaacaagaaattgacccagtaatgcaaagc ctcggatattgttgtggcagaaagttggagttctctccacagacactctgttgctatggc aaacagttatgcacaatccctcgtgatgccacttactacagttaccagaacaggtatcat ttctgtgagaagtgtttcaatgaaatccaaggggagagcgtttctttgggggatgaccct tcccagcctcaaactacgataaataaagaacagttttccaagagaaaaaatgacacactg gatcctgaattatttgttgaatgtacagagtgtggaagaaagatgcatcagatctgtgtt cttcatcatgaaattatctggccatctggatttgtttgtgatggctgcttaaagaaatct gcacgaaccaggaaagaaaataagttttctgctaaaaggttgccatctaccaggcttggc acctttctggagaatcgtgtaaatgactttcttaggcgacagaatcaccccgagtccggg gaagtcactgttcgggtagttcatgcttctgacaaaactgtggaagtgaaaccaggaatg aaagcaaggtttgtagatagtggagagatggcagaatcctttccataccgaaccaaagcc ctctttgcctttgaagagatcgacggtgttgacttgtgtttctttggcatgcacgttcaa gagtatggctctgactgccctccacccaaccagaggagagtttacatttcataccttgac agtgttcatttcttccgtcctaaatgcttgaggactgcagtctatcatgaaattctaatt ggatatttagaatacgtcaagaaattagggtacacaacagggcatatttgggcttgtccc ccaagtgagggagacgactatatcttccattgccatcctcctgaccagaagatacccaag cccaagcgactgcaggagtggtacaaaaagatgcttgacaaggccgtgtctgagcgaatc gtccatgactacaaggatatttttaaacaagcgactgaagatcgactaacaagcgcaaag gagctgccttactttgagggcgatttctggcccaacgttctggaagagagcattaaggaa ctggaacaggaggaggaagagcgaaagcgagaggagaacaccagcaatgagagcacagat gtgacgaagggagacagcaaaaatgctaaaaagaaaaataataagaaaaccagcaaaaac aagagcagcctgagtaggggcaacaagaagaagcccggcatgcctaatgtctccaacgac ctctcgcagaagctgtacgccacgatggagaagcacaaggaggtcttctttgtgatccgt ctcatcgctggccctgccgccaactccctgccccccatcgtcgatcccgaccccctcatc ccctgcgatctgatggatgggcgggacgccttccttaccctcgcaagggacaagcacctg gagttctcttcactccgaagagcccagtggtccaccatgtgcatgctggtggagctgcac acccagagccaggaccgctttgtctacacctgcaacgagtgcaagcaccacgtggagacg cgctggcactgcactgtctgcgaggattatgatctgtgtatcacctgctataacactaaa aaccatgaccacaaaatggagaaactaggtctgggcttagatgacgagagcaacagccag caggccgcagccacccagagcccgggggactcgcggcgcctgagcatccagcgctgcatc cagtccctggtgcacgcctgccagtgccgcaacgccaactgctcgctgccgtcctgccag aagatgaagcgggtggtgcagcacaccaagggctgcaagcggaaaaccaacggcggctgc cccatctgcaagcagctcatcgccctctgctgctaccacgccaagcactgccaggagaac aagtgcccggtgcccttctgcctcaacatcaagcagaagctgcggcagcagcagctgcag caccggctccagcaggcccagatgctccgcaggaggatggccagcatgcagcggaccggt gtggtggggcagcagcaaggcctgccctcccccactcctgccactcccaccacgccgacg ggccagcagccggccaccccgcagacgccccagccccagcctccctctcagcctcagccc acgcctcccaacagcatgcccccctacttgcccaggactcaggctgctggccctgtctcc cagggtaaggcggcgggccaggtgacccctcccacacccccccagactgctcagccaccc ctcccggggcccccacctgccgcagtggaaatggcaatgcagattcagagggcggctgag acgcagcgccagatggcccacgtgcaaatttttcaaaggccaatacagcaccagatgccc cagatgactccaatggctcccatgggtatgaacccaccccctatgaccagaggtcccagt gggcatttggagccagggatggggcccacagggatgcagcagcagccacagtgggtccaa ggagggttgcctcagccccagcagctacagcccgggatgccgaggccagccatgatgtca gtggcccagcacggccagcccttgaatatagctccccagccaggactgggccaggtaggt gtgagccctctcaaaccaggcactgtgtctcaacaagccttacaaaaccttttgcggact ctcaggtctcccagctctcccctacagcagcaacaggtgctcagtatccttcacgccaac ccccagctgttggctgcattcatcaagcagcgggctgccaagtacgccagctcgaatccg cagcccctcgctgggcagcccggcatgccccagggccagccggggctgcagccacctgcc atgccgggccagcagggcgtccactccagtccagccatgccgaacatgagccccatgcaa gcgggcgttcagagggccggcctgccccagcagcagccgcagcagccgctccagcccccc atgggagggatgagcccccaggctcagcaaatgaacatgaatcacaacgccatgccttcg cagttccgagacatcttgcggcggcagcagatgatgcagcagcagcagcagggagcgggg cccgggatcggtcccgggatggccaaccataaccagttccagcaaccgcaaggggtgggc taccccccgccgccacagccgcagcagcagcgcatgcagcaccacctgcagcagatgcaa ccggggagcatggggcagatgggccagctcccccaggccttgggagcggaggcgggggcc ggcctgcaggcgtatcagcaacgactcctccagcagcagatggggtcccctgctcagccc aaccccatgagcccccagcagcatatgctcccaagccaggcgcagtccccacacctccaa ggccagcagatcccttcttctctctccaatcaagtgcgctctccccagcctgtcccttct ccacggccgcagtcccagcccccccactccagcccttccccaaggatgcagcctcagcct tcgccacaccacgtctccccgcagaccagttctccacatccgggactggtcgccgcccag gccaaccccatggaacaagggcattttgccagcccggaccagagctcgatgctttctcag ctcgctagcaatccgggcatggcaaacctccacggtgcgggcgccacggacctggggctc ggccccgataacgcggacttgaattcgaacctctcgcagagtacgctagacatacactag

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