Ursus maritimus (polar bear): 103674739
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Entry
103674739 CDS
T03271
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04020
Calcium signaling pathway
umr04022
cGMP-PKG signaling pathway
umr04024
cAMP signaling pathway
umr04218
Cellular senescence
umr04260
Cardiac muscle contraction
umr04261
Adrenergic signaling in cardiomyocytes
umr04270
Vascular smooth muscle contraction
umr04530
Tight junction
umr04713
Circadian entrainment
umr04723
Retrograde endocannabinoid signaling
umr04724
Glutamatergic synapse
umr04725
Cholinergic synapse
umr04726
Serotonergic synapse
umr04727
GABAergic synapse
umr04728
Dopaminergic synapse
umr04911
Insulin secretion
umr04912
GnRH signaling pathway
umr04921
Oxytocin signaling pathway
umr04924
Renin secretion
umr04925
Aldosterone synthesis and secretion
umr04927
Cortisol synthesis and secretion
umr04929
GnRH secretion
umr04930
Type II diabetes mellitus
umr04934
Cushing syndrome
umr04935
Growth hormone synthesis, secretion and action
umr04973
Carbohydrate digestion and absorption
umr05010
Alzheimer disease
umr05020
Prion disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05031
Amphetamine addiction
umr05207
Chemical carcinogenesis - receptor activation
umr05410
Hypertrophic cardiomyopathy
umr05412
Arrhythmogenic right ventricular cardiomyopathy
umr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103674739 (CACNA1D)
04020 Calcium signaling pathway
103674739 (CACNA1D)
04024 cAMP signaling pathway
103674739 (CACNA1D)
04022 cGMP-PKG signaling pathway
103674739 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
103674739 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
103674739 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103674739 (CACNA1D)
04929 GnRH secretion
103674739 (CACNA1D)
04912 GnRH signaling pathway
103674739 (CACNA1D)
04921 Oxytocin signaling pathway
103674739 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
103674739 (CACNA1D)
04924 Renin secretion
103674739 (CACNA1D)
04925 Aldosterone synthesis and secretion
103674739 (CACNA1D)
04927 Cortisol synthesis and secretion
103674739 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
103674739 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
103674739 (CACNA1D)
04270 Vascular smooth muscle contraction
103674739 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103674739 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
103674739 (CACNA1D)
04727 GABAergic synapse
103674739 (CACNA1D)
04725 Cholinergic synapse
103674739 (CACNA1D)
04728 Dopaminergic synapse
103674739 (CACNA1D)
04726 Serotonergic synapse
103674739 (CACNA1D)
04723 Retrograde endocannabinoid signaling
103674739 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
103674739 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103674739 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
103674739 (CACNA1D)
05020 Prion disease
103674739 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
103674739 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
103674739 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103674739 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
103674739 (CACNA1D)
05414 Dilated cardiomyopathy
103674739 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103674739 (CACNA1D)
04934 Cushing syndrome
103674739 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
umr04040
]
103674739 (CACNA1D)
Ion channels [BR:
umr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103674739 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
103674739
NCBI-ProteinID:
XP_040484613
UniProt:
A0A8M1FMK5
LinkDB
All DBs
Position
Unknown
AA seq
2181 aa
AA seq
DB search
MMMMMMMKNMHHQRQQQADHANEANYARGTTLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADTDILAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENQGGCGSLWCWWKRRGTAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYDQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKRNTKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMAT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSSGENVGP
VYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPESDYNPGEEHTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNSDRRDPLQQTNTTHRPLHVQRPSVPP
ASDTERPLFPPAGNSGCHSHHNHNSIGKQAPSSTNANLNNANMSKAAPGKRPSIGNLEHM
SENGHHSSHKHDREPQRRSSIKRTRYYETYIRSDSGDEQCPTICREDPEIHGYFRDSRCL
EEQEYFSGEEGYEDAGSPTWGRQNYSYYSRYPGGSWDFEWPRGYHHPQGFLEDEDSPVCY
DSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPPSPALPHRTALPLHLMQQQIMA
VAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYAPLIQVERPDALDQVNGSLPSLH
RSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASNLLNGTVHPRANGGVGPVSHRQDYELQDFGPGYSDE
EPDPGRDEEDLADEMICITTL
NT seq
6546 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaacatgcaccatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccacactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgatgctgcc
aggcaggccaaggctgcccaaactatgagcacctctgcacccccacctgtgggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccgc
gcctttcgggtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgacacagatatcctagctgaagaggacccagcgccgtgtgcgttctca
gggaatggacgccagtgtgccgccaacggcacggagtgcaggagtggctgggttggccca
aacggaggcatcaccaacttcgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagagagaaggctaaagcccgggga
gacttccagaagctccgggagaagcagcagctggaggaggacctaaagggctacttggat
tggatcacccaagctgaagacattgatcctgagaatgaggaagaaggtggagaggaaagc
aaacgaaacaccagcatgcccaccagcgagacggagtcggtgaacacagagaacgtaagt
ggcggaggcgagaaccaaggcggctgtgggagtctctggtgctggtggaaacgaagaggc
acggccaaggctgggccctctgggtgtcggcggtggggccaagccatttccaaatccaag
ctcagccgacgctggcggcgctggaaccgcttcaatcgcagaagatgtcgggctgctgtg
aagtctgtcacgttttactggctggttatcgtcctggtgtttctcaacaccctaaccatt
tcctctgagcattacgaccagcctgactggctgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcgtatttcgtctctctctttaaccggtttgattgcttcgtggtgtgcggtggaattacc
gagaccatcttggtggagctggaaatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttc
atcatcatcttttccctgcttgggatgcagctgttcggtggcaagtttaattttgacgaa
acgcagaccaagcggagcacctttgacaatttccctcaagcccttctgacagtattccag
atcctgacaggggaagactggaacgccgtgatgtatgacggcattatggcctacggcggc
ccgtcctcttcggggatgatcgtctgtatctacttcatcatcctcttcatttgtggtaac
tatatcctgctgaatgtcttcttggccatcgctgtagacaatctggctgacgcggaaagt
ttgaataccgcccagaaagaggaagctgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggagaataaaaggaacacgaaaccagaagtcaaccagatagccaacagcgac
aataaggttacaattgatgactatcgagaagaggatgaagacaaggacccctaccctcct
tgtgatgtgccagtaggggaagaggaagaggaggaggaagaggacgaacctgaggttcct
gctggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccctatt
cctgaagggagtgcgttcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagtagc
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatggcgacg
tttggagctttcctccacaaaggggctttctgcaggaattacttcaatctgctggatatg
ctggttgttggggtgtccctggtatcatttgggatccaatccagtgccatctccgttgtc
aagattctgagggtcttaagggtcctgcggccactcagggcgatcaacagagcgaaagga
cttaagcacgtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatc
gtcaccacccttctccagttcatgttcgcctgcatcggggtccagttgttcaagggaaag
ttctatcgctgtacagacgaagccaaaagtaaccccgaagagtgcagggggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgtgagaggatctggcaaaatagc
gatttcaacttcgacaacgtcctgtctgctatgatggcgctgttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcgagcggagagaacgtgggccct
gtctacaactaccgagtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggctttgtcatcgtcacgtttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgccagtgtgttgaatacgccttg
aaagcacgtcccctgcggagatacattcccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaacgacgccatggacattctg
aacatggtcttcactggggtgttcaccgtcgagatggttttgaaagtcatcgcgttcaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacccaactgaaagtgaaaatgtccctgtccca
actgccacacccgggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcggttggtgaagcttctcagcaggggggaaggcatccggacattgctg
tggacttttataaagtcctttcaggcactgccctatgttgccctcctcatagccatgctg
ttcttcatctatgcggtgattggcatgcagatgtttgggaaggttgctatgagagataac
aaccagatcaacaggaacaacaatttccagacctttccccaggcggtgctgctgctcttc
aggtgtgccacgggcgaagcctggcaggagatcatgctggcctgcctgccggggaagctc
tgcgaccccgagtcggactacaaccccggggaggagcacacgtgtgggagcaacttcgcc
attgtttatttcatcagtttctacatgctctgcgcgtttctgatcatcaacctgtttgtg
gctgtcatcatggacaactttgattatctgacccgggactggtctattctggggcctcac
catttagatgaattcaaaagaatatggtcggaatacgaccctgaggcaaaaggaaggatc
aagcacctcgatgtggtcactctgctccgccgcatccagcctcccctggggtttgggaaa
ttatgcccacacagagtagcctgtaagagactcgtggccatgaacatgcctctcaacagc
gatgggacggtcatgtttaatgcaaccctgtttgctttggttcgaacagctcttaaaatc
aagacggaagggaacctggaacaagctaatgaagaactccgagctgtgatcaagaaaatc
tggaagaaaaccagcatgaagctgcttgaccaagttgtccctccagccggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagaacaaggcctggtgggaaaataccctgcgaagaacaccaccattgcccta
caggcaggattaaggacactgcatgacattgggccagaaatccggcgtgctatatcatgt
gatttgcaagatgacgagccggaggaaacaaaacgagaagaagaagaagatgtattcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagacccc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcagttccacct
gcaagtgatactgagagaccgctgtttcctccagcaggaaattcggggtgtcatagccat
cataaccataattccataggaaagcaagctcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccctggaaagcggcccagcattgggaaccttgagcatatg
tctgaaaatgggcatcactcctcccacaagcacgaccgggagcctcaaagaaggtccagt
attaaaagaacccgctattatgaaacttacattagatctgactcgggggacgagcagtgc
cccaccatctgccgggaagatccagagatccatggctacttcagggactcccgctgcttg
gaggagcaggaatatttcagtggcgaggagggctatgaggatgccggctcaccgacctgg
ggcaggcaaaactacagctactacagccgatacccaggcggcagctgggacttcgagtgg
ccccgaggctaccatcacccccaaggcttcttggaggatgaggactcgcccgtttgctat
gattcccggagatctccaaggagacgcctactacctcccaccccgacatcccaccggaga
tcctccttcaacttcgagtgcctgcggcggcagagcagccaggaggaggtcccgccgtcc
cctgccctcccccaccgcacagccctgcctctgcacctgatgcagcaacagatcatggca
gttgcgggcctggattccagtaaagcccagaagtactcgccgagccactcgacccggtca
tgggccacccctccggcgacccctccgtaccgggactggacgccatgctacgcacccctg
atccaggtggagcggccggatgccctggaccaggtcaacggcagcctgccatccctgcac
cggagctcatggtacacggacgagcccggcatctcgtaccgaacgttcacaccagccagc
ctgactgtccccagcagcttccgcaacaagaacagtgacaagcagaggagcgcagacagc
ttggtggaggcggtcctgatatctgaaggcttaggacggtatgcaagggaccccaaattt
gtgtcggcaacaaaacacgaaatcgccgatgcttgtgacctgaccatcgacgagatggaa
agtgcagccagcaacctgctcaacgggaccgtgcatccgcgggctaacgggggcgtgggc
cccgtctcccatcggcaggactatgagctccaggacttcgggccgggctacagcgatgaa
gagcccgaccccggaagagatgaggaggacctggcagacgaaatgatctgcatcaccacc
ctgtag
DBGET
integrated database retrieval system
