Entry |
|
Symbol |
ATF4
|
Name |
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
|
KO |
K04374 | cyclic AMP-dependent transcription factor ATF-4 |
|
Organism |
umr Ursus maritimus (polar bear)
|
Pathway |
umr04141 | Protein processing in endoplasmic reticulum |
umr04261 | Adrenergic signaling in cardiomyocytes |
umr04925 | Aldosterone synthesis and secretion |
umr04927 | Cortisol synthesis and secretion |
umr04928 | Parathyroid hormone synthesis, secretion and action |
umr04932 | Non-alcoholic fatty liver disease |
umr04935 | Growth hormone synthesis, secretion and action |
umr05022 | Pathways of neurodegeneration - multiple diseases |
umr05163 | Human cytomegalovirus infection |
umr05166 | Human T-cell leukemia virus 1 infection |
umr05207 | Chemical carcinogenesis - receptor activation |
|
Brite |
KEGG Orthology (KO) [BR:umr00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
103676372 (ATF4)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103676372 (ATF4)
04668 TNF signaling pathway
103676372 (ATF4)
04022 cGMP-PKG signaling pathway
103676372 (ATF4)
04151 PI3K-Akt signaling pathway
103676372 (ATF4)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
103676372 (ATF4)
09143 Cell growth and death
04210 Apoptosis
103676372 (ATF4)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103676372 (ATF4)
04922 Glucagon signaling pathway
103676372 (ATF4)
04912 GnRH signaling pathway
103676372 (ATF4)
04915 Estrogen signaling pathway
103676372 (ATF4)
04926 Relaxin signaling pathway
103676372 (ATF4)
04935 Growth hormone synthesis, secretion and action
103676372 (ATF4)
04918 Thyroid hormone synthesis
103676372 (ATF4)
04928 Parathyroid hormone synthesis, secretion and action
103676372 (ATF4)
04925 Aldosterone synthesis and secretion
103676372 (ATF4)
04927 Cortisol synthesis and secretion
103676372 (ATF4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103676372 (ATF4)
09156 Nervous system
04725 Cholinergic synapse
103676372 (ATF4)
04728 Dopaminergic synapse
103676372 (ATF4)
04720 Long-term potentiation
103676372 (ATF4)
04722 Neurotrophin signaling pathway
103676372 (ATF4)
09149 Aging
04211 Longevity regulating pathway
103676372 (ATF4)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103676372 (ATF4)
05203 Viral carcinogenesis
103676372 (ATF4)
09162 Cancer: specific types
05215 Prostate cancer
103676372 (ATF4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103676372 (ATF4)
05161 Hepatitis B
103676372 (ATF4)
05163 Human cytomegalovirus infection
103676372 (ATF4)
09164 Neurodegenerative disease
05010 Alzheimer disease
103676372 (ATF4)
05012 Parkinson disease
103676372 (ATF4)
05014 Amyotrophic lateral sclerosis
103676372 (ATF4)
05020 Prion disease
103676372 (ATF4)
05022 Pathways of neurodegeneration - multiple diseases
103676372 (ATF4)
09165 Substance dependence
05030 Cocaine addiction
103676372 (ATF4)
05031 Amphetamine addiction
103676372 (ATF4)
05034 Alcoholism
103676372 (ATF4)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103676372 (ATF4)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103676372 (ATF4)
04934 Cushing syndrome
103676372 (ATF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:umr03000]
103676372 (ATF4)
Transcription factors [BR:umr03000]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, CRE-BP/ATF
103676372 (ATF4)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
Unknown
|
AA seq |
351 aa
MAEMSFLNSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQSVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSHCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP |
NT seq |
1056 nt +upstreamnt +downstreamnt
atggccgagatgagtttcctgaacagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggagagcttgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttttcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagacgaataaggagcccccccagagcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttaccttcctg
caaccacttccactttccccaggggccctgtcctccactccagatcattcttttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactctactgcctac
attaccgtgatccctcagtgcataaaggaggaggatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagtccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttcccattgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagacggcagcaaaagtaaaggtcgagaaactagataag
aagctgaaaaagatggagcagaacaagactgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggaaaagaagaatgaggctctg
aaagagagggcagattctttagccaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcaagggagaagaaaagggtcccctag |