KEGG   Ursus maritimus (polar bear): 103676372
Entry
103676372         CDS       T03271                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04022  cGMP-PKG signaling pathway
umr04137  Mitophagy - animal
umr04141  Protein processing in endoplasmic reticulum
umr04151  PI3K-Akt signaling pathway
umr04210  Apoptosis
umr04211  Longevity regulating pathway
umr04261  Adrenergic signaling in cardiomyocytes
umr04668  TNF signaling pathway
umr04720  Long-term potentiation
umr04722  Neurotrophin signaling pathway
umr04725  Cholinergic synapse
umr04728  Dopaminergic synapse
umr04911  Insulin secretion
umr04912  GnRH signaling pathway
umr04915  Estrogen signaling pathway
umr04918  Thyroid hormone synthesis
umr04922  Glucagon signaling pathway
umr04925  Aldosterone synthesis and secretion
umr04926  Relaxin signaling pathway
umr04927  Cortisol synthesis and secretion
umr04928  Parathyroid hormone synthesis, secretion and action
umr04932  Non-alcoholic fatty liver disease
umr04934  Cushing syndrome
umr04935  Growth hormone synthesis, secretion and action
umr05010  Alzheimer disease
umr05012  Parkinson disease
umr05014  Amyotrophic lateral sclerosis
umr05020  Prion disease
umr05022  Pathways of neurodegeneration - multiple diseases
umr05030  Cocaine addiction
umr05031  Amphetamine addiction
umr05034  Alcoholism
umr05161  Hepatitis B
umr05163  Human cytomegalovirus infection
umr05166  Human T-cell leukemia virus 1 infection
umr05203  Viral carcinogenesis
umr05207  Chemical carcinogenesis - receptor activation
umr05215  Prostate cancer
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    103676372 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103676372 (ATF4)
   04668 TNF signaling pathway
    103676372 (ATF4)
   04022 cGMP-PKG signaling pathway
    103676372 (ATF4)
   04151 PI3K-Akt signaling pathway
    103676372 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    103676372 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    103676372 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    103676372 (ATF4)
   04922 Glucagon signaling pathway
    103676372 (ATF4)
   04912 GnRH signaling pathway
    103676372 (ATF4)
   04915 Estrogen signaling pathway
    103676372 (ATF4)
   04926 Relaxin signaling pathway
    103676372 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    103676372 (ATF4)
   04918 Thyroid hormone synthesis
    103676372 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    103676372 (ATF4)
   04925 Aldosterone synthesis and secretion
    103676372 (ATF4)
   04927 Cortisol synthesis and secretion
    103676372 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103676372 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    103676372 (ATF4)
   04728 Dopaminergic synapse
    103676372 (ATF4)
   04720 Long-term potentiation
    103676372 (ATF4)
   04722 Neurotrophin signaling pathway
    103676372 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    103676372 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    103676372 (ATF4)
   05203 Viral carcinogenesis
    103676372 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    103676372 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103676372 (ATF4)
   05161 Hepatitis B
    103676372 (ATF4)
   05163 Human cytomegalovirus infection
    103676372 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103676372 (ATF4)
   05012 Parkinson disease
    103676372 (ATF4)
   05014 Amyotrophic lateral sclerosis
    103676372 (ATF4)
   05020 Prion disease
    103676372 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    103676372 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    103676372 (ATF4)
   05031 Amphetamine addiction
    103676372 (ATF4)
   05034 Alcoholism
    103676372 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103676372 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103676372 (ATF4)
   04934 Cushing syndrome
    103676372 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:umr03000]
    103676372 (ATF4)
Transcription factors [BR:umr03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    103676372 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU KIF21A Asd-4 AAA_13 Nop53 bZIP_Maf OVT1 DUF3450 Laminin_II
Other DBs
NCBI-GeneID: 103676372
NCBI-ProteinID: XP_008703764
UniProt: A0A384DAF2
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLNSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQSVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSHCGSARPKPYDPPGEKTAAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgaacagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggagagcttgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttttcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagacgaataaggagcccccccagagcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttaccttcctg
caaccacttccactttccccaggggccctgtcctccactccagatcattcttttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactctactgcctac
attaccgtgatccctcagtgcataaaggaggaggatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagtccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttcccattgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagacggcagcaaaagtaaaggtcgagaaactagataag
aagctgaaaaagatggagcagaacaagactgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggaaaagaagaatgaggctctg
aaagagagggcagattctttagccaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcaagggagaagaaaagggtcccctag

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