Ursus maritimus (polar bear): 103676974 Help Entry 103676974         CDS       T03271                                  Symbol HDAC2 Name (RefSeq) histone deacetylase 2   KO K06067   histone deacetylase 1/2 [EC:3.5.1.98] Organism umr  Ursus maritimus (polar bear) Pathway umr03082   ATP-dependent chromatin remodeling umr03083   Polycomb repressive complex umr04110   Cell cycle umr04213   Longevity regulating pathway - multiple species umr04330   Notch signaling pathway umr04350   TGF-beta signaling pathway umr04613   Neutrophil extracellular trap formation umr04919   Thyroid hormone signaling pathway umr05016   Huntington disease umr05031   Amphetamine addiction umr05034   Alcoholism umr05165   Human papillomavirus infection umr05169   Epstein-Barr virus infection umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05203   Viral carcinogenesis umr05206   MicroRNAs in cancer umr05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:umr00001]  09120 Genetic Information Processing   09126 Chromosome    03082 ATP-dependent chromatin remodeling     103676974 (HDAC2)    03083 Polycomb repressive complex     103676974 (HDAC2)  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     103676974 (HDAC2)    04350 TGF-beta signaling pathway     103676974 (HDAC2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103676974 (HDAC2)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     103676974 (HDAC2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     103676974 (HDAC2)   09149 Aging    04213 Longevity regulating pathway - multiple species     103676974 (HDAC2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103676974 (HDAC2)    05202 Transcriptional misregulation in cancer     103676974 (HDAC2)    05206 MicroRNAs in cancer     103676974 (HDAC2)    05203 Viral carcinogenesis     103676974 (HDAC2)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     103676974 (HDAC2)   09172 Infectious disease: viral    05169 Epstein-Barr virus infection     103676974 (HDAC2)    05165 Human papillomavirus infection     103676974 (HDAC2)   09164 Neurodegenerative disease    05016 Huntington disease     103676974 (HDAC2)   09165 Substance dependence    05031 Amphetamine addiction     103676974 (HDAC2)    05034 Alcoholism     103676974 (HDAC2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:umr03036]     103676974 (HDAC2) Enzymes [BR:umr01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.1  In linear amides     3.5.1.98  histone deacetylase      103676974 (HDAC2) Chromosome and associated proteins [BR:umr03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     Class I HDACs      103676974 (HDAC2)    HDAC complexes     Sin3A-HDAC complex      103676974 (HDAC2)     BRAF-HDAC complex      103676974 (HDAC2)     REST complex      103676974 (HDAC2)     SHIP complex      103676974 (HDAC2)     MiDAC complex      103676974 (HDAC2)    Polycomb repressive complex (PRC) and associated proteins     Noncanonical PRC1 (PRC1.6)      103676974 (HDAC2)   Heterochromatin formation proteins    Other heterochromatin formation proteins     103676974 (HDAC2)   Chromatin remodeling factors    NuRD complex     103676974 (HDAC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hist_deacetyl Motif Other DBs NCBI-GeneID:  103676974 NCBI-ProteinID:  XP_040483593 UniProt:  A0A8M1FJN3 LinkDB All DBs Position Unknown AA seq 488 aa AA seqDB search MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKADVKEEDKSKDSSGEKTDTKGA KSEQLSNP NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt atggcgtacagtcagggaggcggcaagaagaaagtctgctactactacgatggtgatatt ggaaattactattatggacagggtcatcccatgaaacctcatagaatccgcatgacccat aacttgctgctaaattatggcttatatagaaaaatggaaatatataggccccataaagcc actgctgaagaaatgacaaaataccacagtgatgagtacatcaaatttctacgttcaata agaccagataacatgtctgagtatagtaagcagatgcagagatttaatgttggagaagat tgtccagtgtttgatggactctttgagttttgtcagctctcaactggtggctcggttgct ggggctgtgaagttaaaccgacaacaaactgatatggctgttaactgggctggaggatta catcatgctaagaaatcagaagcatcaggattctgttacgttaatgatattgtacttgct atccttgaattactaaagtatcatcagagagtcttatatattgatattgatatccatcat ggtgatggtgttgaagaagctttttatacgacagatcgtgtaatgactgtatcattccat aaatatggggaatactttcctggaacaggagacttgagggatattggtgcaggaaaaggc aaatactatgctgtcaattttccaatgagagatggtatagatgatgaatcctatgggcag atatttaagcctattatctcaaaggtgatggagatgtaccagcccagtgccgtggtgctc cagtgtggtgcggactcactgtctggtgacaggctcgggtgcttcaatctgacagtcaaa ggtcatgctaaatgtgtagaagttgtgaaaactttcaatttaccattactgatgcttggg ggaggtggatacacaattcgtaatgttgctcgatgttggacatacgagactgcagttgcc ctcgattgtgagattcccaatgaattgccatataatgattactttgagtattttggtccg gacttcaaactgcatattagtccttcaaacatgacaaaccagaacactccagaatatatg gaaaagataaaacagcgtttatttgaaaatttacgcatgttacctcatgcacctggcgtc cagatgcaagctattccagaagatgctgttcatgaagacagcggagatgaagatggagaa gatccagataagagaatttctattcgagcctcagacaaacggatagcttgtgatgaagaa ttctcagattctgaggatgaaggagaaggaggacgtagaaatgtggctgatcataagaaa ggagcaaagaaagctagaattgaagaagacaagaaggaaacggaggacaaaaaagcagac gttaaggaagaagataaatccaaggacagtagtggtgaaaaaacagataccaaaggagcc aaatcagaacagctcagcaacccttga

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