Ursus maritimus (polar bear): 103677132
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Entry
103677132 CDS
T03271
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2
KO
K20994
Notch 2
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01522
Endocrine resistance
umr04330
Notch signaling pathway
umr04658
Th1 and Th2 cell differentiation
umr04919
Thyroid hormone signaling pathway
umr05165
Human papillomavirus infection
umr05200
Pathways in cancer
umr05206
MicroRNAs in cancer
umr05207
Chemical carcinogenesis - receptor activation
umr05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
103677132 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103677132 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103677132 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103677132 (NOTCH2)
05206 MicroRNAs in cancer
103677132 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
103677132 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
103677132 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
103677132 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
103677132 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
Ank_2
Ank
Notch
NOD
EGF_2
NODP
Ank_5
Ank_3
Ank_4
EGF_3
JAG1-like_EGF2
DL-JAG_EGF-like
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
103677132
NCBI-ProteinID:
XP_040482781
UniProt:
A0A8M1FHC8
LinkDB
All DBs
Position
Unknown
AA seq
2310 aa
AA seq
DB search
MAQAMLGKATCRCALGFTGDDCQYSTTHPCFVSHPCLNGGTCHVRSRDDYECTCQHCDSP
YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGITCERNIDDCPNHKCQNGGVCVDGVNT
YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDD
CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC
TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECH
SDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP
PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCDENIDNCDPDPCHH
GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGIN
CEINFDDCASNPCVHGVCMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDV
NGFRCLCPEGPHHPSCYSQVNECLSSPCIHGNCTGGLSGYKCLCDAGWVGINCEVDRNEC
LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCQC
VLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESYTCLCAPGWQGQRCTVDIDECVSKP
CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCHPGF
IGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQSGFDGVHCENNIDECTESSCFNGGT
CIDGINSFSCLCPVGFTGPFCLHEINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQ
TLVNLCSRSPCKNKGTCIQEKAESRCLCPSGWAGAYCDVPNVSCEVAAFHRGVSTDHLCQ
HSGVCINAGNSHHCQCPLGYTGSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQG
VNCEYEVDECQNQPCQNGGTCVDLVNHFKCSCPPGTRGLLCEENIDDCAGGPRCLNGGQC
VDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRNAFTGRHC
ETFIDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCVHTA
SGPRCFCPNPQDCESGCASSPCQHGGSCYPQRQPPYYSCQCSPPFWGSHCELYTAPTSTP
PATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCD
ELCNTAECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPEN
LAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAAMK
KQKMTRRSLPGDQEQEVAGSKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSY
PLVSVVSESLTPKRTQLLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDS
SNHKRREPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEED
DAIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGS
SDMSDEDEDGEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGA
DANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVA
ELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREG
SYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALS
PVICGPNRSFLSLKHTPMGKKPRRPNTKSTMPTSLPNLAKEGKDAKGSRRKKSLSDKGQL
SESSVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSF
SNLHEMQPLAHGASTVLPSVSQLLSHHHIVPPGSSSAGSLSRLHPVTVPADWMNRMEMNE
TQYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGNIAQPAGT
PQPQSNCPPPVAGPVPTMYQIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVG
KYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTT
SPTPGGAGGGQRGPGTHMSEPPRSNMQVYA
NT seq
6933 nt
NT seq
+upstream
nt +downstream
nt
atggcccaggccatgttggggaaagccacatgccgatgtgccctggggttcacaggagat
gattgccagtactcgaccactcacccctgctttgtttctcacccctgcctgaatggaggc
acctgccacgtgcgtagccgggatgactatgagtgcacctgccaacactgtgacagcccc
tacgtgccctgtgcaccctccccctgtgtcaatggtggcacctgccggcagactggtgac
ttcacgtttgaatgcaactgccttccaggttttgaggggatcacctgtgagcggaatatt
gatgactgccctaaccacaagtgtcagaatggaggggtttgtgtggatggggttaatact
tacaactgtcgctgcccccctcagtggacaggacagttttgcacagaggatgtggatgag
tgtctgctgcaacctaatgcttgtcagaatgggggcacctgtaccaaccgcaatgggggc
tatggctgtgtatgtgttaatggctggagtggagatgactgcagtgagaacattgatgac
tgtgccttcgcctcctgcactccgggctccacctgcattgaccgtgtggcctccttctct
tgcatgtgcccagaaggaaaggcaggtctcttatgtcatctggatgatgcatgcatcagc
aatccttgccacaagggggcactgtgtgataccaaccccctgaatgggcagtatatttgc
acctgcccccaaggctacaaaggggctgactgcacagaagatgtggatgagtgtgccatg
gccaatagcaatccttgtgagcacgcaggaaaatgtgtgaacacagatggtgccttccac
tgtgaatgtctgaagggctatgcagggcctcgttgtgagatggacatcaatgagtgccat
tccgacccctgccagaacgatgcaacctgtctggataagattggaggcttcacgtgtctg
tgcatgccaggtttcaaaggtgtgcattgtgaattggagataaacgaatgtcagagcaac
ccttgtgtgaacaatggtcagtgtgtggataaagtcaatcgcttccagtgtctgtgtccg
cctggtttcactgggccagtttgccagattgatattgatgactgttccagtactccatgt
ctgaatggggcaaagtgtattgatcacccgaatggctatgaatgccagtgtgccacagga
ttcactggtgtgttgtgtgatgagaacatcgacaactgtgaccctgatccttgccaccac
ggccagtgtcaggatgggattgattcctacacctgcatctgcaacccagggtacatgggt
gccatctgcagtgaccagatagatgagtgttacagcagcccctgcctgaatgacggccgc
tgcatcgacctggtgaatggctaccagtgcaattgccagcccggcacgtcaggtattaat
tgtgaaatcaattttgatgactgtgcaagtaacccttgtgtccatggagtctgtatggat
ggcattaatcgttacagttgtgtctgctcaccaggattcacagggcagagatgtaacatt
gacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacgtgcatcaacgatgtg
aatggtttccgctgtctgtgccctgagggtccccatcaccccagctgctactcacaggtg
aacgagtgcctgagcagcccctgcatccatggaaactgtactgggggcctcagtggatac
aagtgcctctgtgatgcaggctgggttggcatcaactgcgaagtggacagaaatgaatgt
ctttctaacccatgccagaatggaggaacttgtgacaatctggtgaatggatacaggtgt
acttgcaagaagggctttaaaggctataactgtcaggtgaatattgatgaatgtgcttca
aatccgtgtctgaaccaaggaacctgctttgatgacataagtggctatacttgccagtgt
gtgctgccatacacaggcaagaattgtcagacagtgttggctccctgttccccaaacccg
tgtgagaatgctgctgtttgcaaagaggcaccaaattttgagagttacacctgcctgtgt
gcccctggctggcaaggtcagcggtgtacagttgacattgatgagtgtgtctccaagccc
tgcatgaaccacggtctctgccataacacccagggcagctatatgtgtgagtgtcctcca
ggcttcagtggtatggactgtgaggaggacatcgatgactgccttgccaatccttgccag
aatggaggttcctgtgtagatggagtgaatactttctcctgcctgtgccatcctggcttt
attggggataagtgtcagacagacatgaatgagtgtctgagtgaaccctgtaagaatgga
gggacctgctctgactatgtcaacagttacacttgcaagtgccagtcgggatttgatgga
gtccactgtgagaacaacattgacgagtgcactgagagctcctgtttcaatggtggcacc
tgtatcgacgggattaactccttctcttgcttgtgccctgtgggcttcactggccccttc
tgcctccatgagatcaatgaatgcaactctcatccatgcctaaatgaaggaatatgtgtc
gatggcctgggtacttaccgctgcacctgccccttgggctacactgggaaaaactgtcag
accctggtgaacctctgtagtcggtctccatgtaagaacaaaggtacctgcattcaggaa
aaagcagagtcccggtgcctgtgtccatccggatgggctggtgcttactgtgatgtgccc
aatgtatcctgtgaggtggcggccttccacagaggggtgtccactgaccacctgtgccag
cactccggcgtctgcatcaatgctggcaactcacatcactgccagtgccccctgggctac
actgggagctactgtgaggagcagcttgatgagtgctcatccaatccctgccagcacgga
gccacctgcagggacttcatcggcgggtacagatgtgagtgtgtcccaggctatcagggc
gtcaattgcgagtatgaagtagatgagtgccagaatcagccatgccagaacgggggcacc
tgtgtcgaccttgtgaaccacttcaaatgctcctgtccaccaggcactcgaggcctgctt
tgtgaagagaacatcgatgactgtgccgggggcccccgctgccttaacggtggtcagtgt
gtggataggatcgggggctacagctgtcgctgcttgcctggttttgccggagagcggtgt
gaaggggacatcaacgagtgcctctcgaacccctgcagctctgagggcagcctggactgc
atccagctaaccaacgactacctgtgtgtctgccgcaacgccttcactggtcgtcactgt
gaaactttcattgatgtgtgtccccagatgccttgcctgaatggggggacttgtgctgtg
gccagcaacatgcctgatggtttcatttgtcgttgtcccccgggattctccggggcaaga
tgccagagcagctgtggacaagtgaagtgcaggagaggggagcagtgtgtgcacacggcc
tcgggacctcgctgcttctgtcccaacccccaggactgcgaatcaggctgtgccagtagc
ccctgccagcatgggggtagctgctatcctcaacgccagcctccttactactcttgccag
tgttctccaccattctggggcagccactgtgaactttacacggcccccaccagcacccct
cctgccacgtgcctgagccagtactgtgccgacaaagctcgggatggcgtctgcgatgag
gcctgcaatagccatgcctgccagtgggatgggggtgactgttccctgaccatggaaaac
ccctgggccaactgctcttccccacttccctgctgggattacatcaacaaccagtgcgat
gagctgtgcaacacagccgagtgcctttttgacaattttgagtgccaggggaacagcaag
acgtgcaagtatgacaaatactgtgcagaccacttcaaagacaaccattgtgaccaggga
tgcaacagtgaggagtgtggctgggacgggctggactgtgctgctgaccggccagagaac
ctggcagaggggaccctggttatagtggtgctcatgcccccggagcagctgctccaggac
gcccgcagcttcctgcgggcgctgggcaccctgctccataccaacctgcacattaaacgg
gactcgcagggggcactcatggtctacccctattatggtgagaagtcagctgccatgaag
aagcagaagatgactcgcaggtcccttcctggtgatcaagagcaggaggtggctggctct
aaggtatttctggaaattgacaaccgccagtgtgttcaagattcagaccagtgtttcaag
aacacagatgcagcggcagctcttctggcttctcatgccatccaggggaccttgtcctac
cctcttgtgtctgtcgtcagtgaatctctgactccaaaacgcactcagcttctctatcta
cttgctgtggctgtcgtcattatcctgtttattatcctgctgggagttatcatggcgaaa
cgaaagcgcaagcatggctccctctggctgcctgaaggtttcacccttcgccgagactcc
agcaatcacaagcgtcgtgagccagtgggacaggatgccgtggggctgaaaaatctctca
gtgcaagtctcagaagctaacctaattggttctggaacaagtgaacattgggttgatgat
gaagggccccagccaaagaaagccaaggctgaagatgaggctttgctctcagaggaagat
gatgccattgatcgacgtccatggacacagcagcaccttgaggctgcagatatccgcagg
acaccatcgctggcgctcactcctccacaggcggagcaggaggtagacgtgctggacgtg
aatgtccgtggcccagatgggtgcaccccactgatgctggcttctctccgaggaggcagc
tcagatatgagcgatgaagatgaagatggagaggactcttctgccaacatcatcacagac
ttggtctaccagggtgccagcctgcaggcccagacagaccggacaggtgaaatggcactg
caccttgcggcccgctactcgagggctgatgctgccaagcgtctcctggatgcaggtgcg
gacgccaacgcgcaggacaacatgggccgctgccctctccatgctgcagtggcagctgac
gcccagggggtcttccagattctgatccgcaaccgagtaactgatctggatgccaggatg
aacgatggcactacaccgctgatcctggccgcccgcctagctgtggagggaatggtggca
gaactgatcaactgccaagcagatgtgaacgcagtggatgaccatgggaaatctgctctt
cactgggcagctgctgtcaataacgtggaggcaacccttttgctgttgaaaaacggggcc
aaccgagacatgcaggacaacaaggaagagacacctctgtttcttgctgcccgggaggga
agctatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagaccac
atggatcgtcttccccgggatgtggctcgagaccgcatgcaccatgacattgtgcgcctc
ctggatgagtacaatgtgacaccaagccctccaggcactgtgctgacttctgccctctca
cctgtgatctgtgggcccaacagatctttcctcagcctaaagcataccccaatgggcaag
aagcctagacggcccaataccaagagtaccatgcccactagcctccctaaccttgccaag
gagggcaaggatgccaagggtagtaggaggaaaaagtctctgagtgacaagggtcagctg
tctgagagctcagtgactttatcccccgttgattccttagaatctcctcacacatatgtt
tctgacaccacatcctctccaatgattacatcccctggaatcttacaggcctcgcccaac
cctatgttggccactgctgccccccctgccccagtccatgcccagcatgcactgtctttc
tctaacctgcatgaaatgcagcctttggctcatggggccagcactgtgcttccctcagtg
agccagctgctgtcccaccaccacattgtccccccaggcagtagcagtgcgggaagcttg
agtaggctccatcctgtcactgttccggcagattggatgaaccgcatggagatgaatgag
acccagtacaatgagatgtttggtatggttctggctccagctgagggcacgcaccctggc
atagctccccagagcaggccacctgaagggaagcacataactacccctcgggagcctttg
ccccccattgtgactttccagctaatccccaaaggcaatattgcccaaccggctgggact
ccccagcctcagtccaactgccctcctcctgttgcaggccctgtgcccaccatgtaccag
attccagaaatggctcgtttgcccagtatggctttccccactgccatgatgccccagcag
gatgggcaggttgctcagaccattctccctgcctatcatccttttccagcctctgtgggc
aagtaccctacaccaccttcgcagcatagttatgcttcctcaaatgctgctgagcgaaca
cccagtcacagtggtcacctgcagggtgaacatccctacctgacaccatccccagagtct
cctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgaccacc
agccctacccctgggggtgctggaggaggtcagcggggacctggaacacacatgtctgag
ccaccacgcagcaacatgcaggtttatgcatga
DBGET
integrated database retrieval system
