Ursus maritimus (polar bear): 103677754
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Entry
103677754 CDS
T03271
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6 isoform X1
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04150
mTOR signaling pathway
umr04310
Wnt signaling pathway
umr04928
Parathyroid hormone synthesis, secretion and action
umr05010
Alzheimer disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05200
Pathways in cancer
umr05224
Breast cancer
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
103677754 (LRP6)
04150 mTOR signaling pathway
103677754 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
103677754 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103677754 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103677754 (LRP6)
05226 Gastric cancer
103677754 (LRP6)
05224 Breast cancer
103677754 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
103677754 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
103677754 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
umr04131
]
103677754 (LRP6)
Membrane trafficking [BR:
umr04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
103677754 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
DUF5050
SGL
EGF_LRP2
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
103677754
NCBI-ProteinID:
XP_040498101
UniProt:
A0A8M1GQV9
LinkDB
All DBs
Position
Unknown
AA seq
1613 aa
AA seq
DB search
MGAVLRSLLACSFCALLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVF
GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE
VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINTE
IYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT
DWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS
PVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR
HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT
DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD
RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL
LGDYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVHRIIGSNPCAEENGGCS
HLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG
VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY
WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG
SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ
YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC
SHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP
IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPNQNLEIQPYDLS
IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERS
PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE
DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ
EYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGE
IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK
NCEVLCLIDQFRCSNGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGV
IVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMS
RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM
EFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDL
NYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
NT seq
4842 nt
NT seq
+upstream
nt +downstream
nt
atgggggccgtcctgaggagcctcctggcctgcagtttctgtgcgctcctgagagcggcc
cctttgttgctttatgcaaacagacgggacttgcgattggttgatgctacaaatggcaaa
gagaatgctacgattgtagttggaggcttggaggatgcagctgcggtggactttgtgttt
ggtcatggcttgatatactggagtgatgtcagcgaagaagccattaaacgaacagagttt
aacaaaactgagagtgtacagaatgttgttgtctctggattattgtcccctgatgggctg
gcatgtgattggcttggagaaaaattatactggacagattctgaaacaaatcggattgaa
gtttctaatttagatggatctttacggaaagttttattttggcaagaattggatcaaccc
agagctattgccttagatccttcaagtgggttcatgtactggacagactggggagaagta
ccaaagatagaacgtgctggaatggatggttcaagtcgattcattataataaacactgaa
atttactggccaaatggactgactttggattatgaggaacagaagctttattgggcagat
gcaaaactcaatttcatccacaaatcaaatctggatggaacaaatcggcaggcagtggtt
aaaggttctcttccacatccttttgccttgacattatttgaggacacattgtactggact
gactggaatacacactctattttggcttgcaacaagtacactggcgagggtctgcgtgaa
atccattctaacatcttctctcccatggatatacatgccttcagccaacagaggcagcca
aatgctacaaatccatgtggaattgataatggtggttgttcccacttgtgtttgatgtct
ccagtcaaacctttttatcagtgtgcttgcccaactggggtcaaactcctggagaatgga
aaaacctgcaaagatggtgccactgaattactgcttttagcacgaaggacagacttgaga
cgcatttctttggatacaccagatttcacagacattgttttacagttagaagacatccgt
catgccattgccatagattatgatcctgtggaaggctatatctactggactgacgatgaa
gtgagggccatacgccgctcattcatagatggatctggcagtcagtttgtggtcactgct
caaattgcgcatcctgatggtattgctgttgactgggttgcccgaaatctttattggaca
gacactggcactgatcggatagaagtgacaaggctcaatgggaccatgaggaagatcttg
atttcagaggacttagaggaaccccgagccattgtgttagatcccatggttgggtacatg
tattggactgactggggagaaatcccgaaaattgagcgagcagctctggatggttctgac
cgagtagtgttggttaacacttctcttggttggccgaatggtttagccttggattatgat
gaaggcaaaatatactggggagatgccaaaacagacaaaattgaggttatgaatactgat
ggcactgggagacgagtactagtggaagacaaaattcctcacatatttgggtttactttg
ttgggtgactatgtttactggactgactggcagagacgtagcatcgaaagagtacacaaa
cgaagcgcagagagggaaatcatcatagatcagcttcctgacctcatgggcctaaaggcc
acaaatgttcatcgaatcattggttccaacccctgcgctgaggaaaatgggggatgtagc
catctttgcctctataggcctcagggcctccgctgtgcctgccccattggctttgaactc
atcagtgacatgaagacctgcattgtcccagaggctttccttttgttttcacggagagca
gatatcaggcgaatttctttggaaactaacaataataatgtggccattcctctcactggt
gtcaaagaagcttctgctttggattttgatgtaacagacaaccgcatttactggactgat
atatcactcaagaccatcagcagagcctttatgaatggcagtgcgctggaacacgtggta
gaattcggcttagattatccagaaggcatggcagtagactggctggggaagaacttgtac
tgggcagacacaggaacgaatcgaattgaggtgtcaaagttggatgggcagcaccgacaa
gttttggtgtggaaagacttagatagtcccagagctcttgcactggaccctgctgaagga
tttatgtattggactgaatggggtggaaaacctaagatagaccgagctgccatggatgga
agtgaacgtactacattagttccaaatgtgggacgggcaaatggcttaactattgattat
gctaaaaggaggctttattggacagacctggacaccaacttaatagaatcttcaaatatg
cttggactcaaccgtgaagttatagcagatgacttgcctcatccttttggcttaactcag
taccaagattacatctactggacggactggagccgacgcagcattgaacgtgccaacaaa
accagtggccaaaaccgcaccatcattcagggccatttggattatgtgatggacatcctc
gtctttcactcctctcggcaggcggggtggaatgagtgtgcttccagcaatgggcactgc
tcccacctctgcttggctgtgccagttggaggttttgtttgtggatgccctgcccactac
tcacttaatgctgacaacaggacttgtagtgctccaactactttcctgctcttcagtcaa
aagagtgccatcaaccgcatggtgattgatgagcagcagagccctgacatcatccttcct
atccacagccttcggaatgtccgggccattgactatgacccactggacaagcaactctat
tggattgactcacgacaaaacatgatccgaaaagcacaagaagacggcagccagggcttt
actgtcgttgtgagctcagttccaaatcagaacctagaaatacaaccctatgacctcagc
attgatatttatagccgctacatttactggacttgtgaggccaccaatgtcattaatgta
acaagattagatgggagatcaattggagtggtactaaaaggcgagcaagacagacctcga
gccattgtggtgaacccggagaaggggtatatgtattttaccaatcttcaggaaaggtct
cccaaaattgaacgggccgctttggatggaacagaacgggaggttctctttttcagtggc
ttaagtaaaccaattgcgttagcccttgatagcagattgggcaagctcttttgggcagat
tcagacctccggcgaattgaaagcagtgatctctcaggtgccaaccggatagtattagaa
gactccaatatcttgcagcctgtgggactgactgtgtttgaaaactggctatattggatt
gataagcagcagcaaatgattgaaaaaattgacatgacaggccgagagggtagaaccaaa
gtccaggctcgaattgcccagcttagtgacattcatgcagtgaaagagctgaaccttcag
gaatatagacagcacccttgtgctcaggataatggtggctgttcacatatttgtcttgta
aaaggagatggtactacaaggtgctcttgccccatgcacttggttctgcttcaagacgag
ctatcatgtggagaacccccaacatgttctcctcagcagtttacttgtttcacgggagaa
attgactgtatccctgtggcttggcgctgcgacgggtttactgaatgcgaagaccacagt
gacgaactcaattgtcctgtatgctcagagtcccagttccagtgtgccagtgggcagtgt
attgatggtgccctccgatgcaatggagatgcaaactgccaggataaatcagatgagaag
aactgtgaagtgctttgtttaattgatcagttccgctgttccaacggtcagtgcattgga
aaacataagaaatgtgatcataatgtggactgcagtgacaagtcagatgaactggattgt
tatccaactgaggaaccagctccacaggccaccaacacagttggttccgttattggagta
attgtcaccatttttgtgtctggaaccatatactttatctgccagagaatgttgtgtcca
cgtatgaagggggatggggaaaccatgactaatgactatgtcgttcatggaccagcttct
gtgccccttggttatgtgccacatccaagttctttgtcaggatctcttccaggaatgtct
cgaggtaaatcaatgatcagctccctaagtatcatggggggaagcagtggacccccttac
gaccgagctcatgtcacaggagcatcatcgagtagttcttcaagcaccaaaggcacttac
ttccctgcaattttgaaccctccaccatccccagccacagagcgatcacattacactatg
gaatttggttattcttcgaatagtccttccactcataggtcctacagctacaggccgtac
agctaccggcactttgcaccccctaccacaccctgcagcacagatgtttgtgacagtgac
tatgctcccagccggagaatgacctcagtggcaacagccaagggctacactagtgacttg
aactatgactcagagcctgtgcccccacctcccacaccccgaagccaatacctgtcagca
gaagagaactatgaaagctgcccaccttctccatacacagagaggagctactctcatcac
ctctacccaccaccgccctctccctgtacagactcctcctga
DBGET
integrated database retrieval system
