Ursus maritimus (polar bear): 103678890
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Entry
103678890 CDS
T03271
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr03030
DNA replication
umr03410
Base excision repair
umr03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
103678890 (POLE)
03410 Base excision repair
103678890 (POLE)
03420 Nucleotide excision repair
103678890 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
umr03032
]
103678890 (POLE)
03400 DNA repair and recombination proteins [BR:
umr03400
]
103678890 (POLE)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
103678890 (POLE)
DNA replication proteins [BR:
umr03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
103678890 (POLE)
DNA repair and recombination proteins [BR:
umr03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
103678890 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
CENP-B_dimeris
Motif
Other DBs
NCBI-GeneID:
103678890
NCBI-ProteinID:
XP_040476030
UniProt:
A0A8M1F1U8
LinkDB
All DBs
Position
Unknown
AA seq
2279 aa
AA seq
DB search
MDRVMFSEDRISLLLSFRDDGPSSSVSALKRLERSQWTDKMDSRFGFERLKEPGEKTGWL
VNMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFLSKK
FQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDLVRVRKDVSPAVKKNREQGHA
SDAYTAMLSSVLQGGSVVIDEEEASKKVTDQLDNVVDMREYDVPYHIRLSIDLKIHVAHW
YNVRYRGSAFPVEISRRDDLVERPDPVVLAFDIETTKLPLKFPDPETDQIMMISYMIDGQ
GYLITNREIVSDDVEDFEFTPKPEYEGPFCVFNEPDEGHLIQRWFEHVQETKPTIMVTYN
GDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKASQCIHMDCLRWVKRDSYLPVGSHN
LKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCT
IIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYVGGH
VEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPMEQVTNFQEVCDQI
KTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAVVDEATCAACDFNKPGADC
QRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTAEGPPRAFHELSREEQAKYEKRRL
SDYCRKAYKKIHVTRVEERLTTVCQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAM
ELGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRRGARWYSMEMAGIVCFTGANII
TQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTASVKKPKVTISYPGAMLNIMVKE
GFTNDQYQELTEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDG
SLAELKGFEIKRRGELQLIKIFQSSVFEAFLKGSTLEDVYGSVAKVADYWLDVLYSKAAN
MPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRK
PEGSPVTERAIPLAIFQAEPMVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQK
IITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVCKQKKISELFVLEGRRQVGTARAPEG
TQSLGAPDMEDFGLVKPPHSAVPVATKRKRILWESQEGSQDMELTVPWQEILGQPPALGT
TQEEWLVWLRFHKKKWQLQARQRLARKKRRRVEVAEGGPLPGAVRDRPTTGLGSFLRRTA
RSILDLPWQIVQISETGQAGLFRLWAVISSDLHCIRLSIPRVFYVNQRVAKAEEGPSYRK
VSRVLPRSNMVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQLGC
VCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHLYLYHHAQGHKALFGLF
VPSQRRASVFVLDTVRSNQMPSLSALYSAEHSLLMERVGPELLPPPKHTFEVRAETDMKT
ICRAIQRSLLAYKEERRGPTLIAVQSNWELKRLASEVPVLEEFPLVPVHVADKISYGVLD
WQRLGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHSHL
LWLSPTSRPDLGGKEADDNRLVMEFDDQASVEINYPGCYSTVCVELDIQNLAVNTILQSH
HINDLEGADSVGISFDVIQQASLEDMITGNQAASTLASYDETALCSSTFRILKSMVVGWV
KEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSV
VYANFNRIVLCTRKRRIEDAVAYVEYVTSSIHSKEIFHSLTISFSRCWEFLLWMDPSNYG
GIKGDVPSRIHCGQQDSPKGGGEEEEEEEEEEEEEEEEEGAQEPDVEDKLENSWNIVQFL
PQAASCQSYFLMIVSAYVVAVYHSMKEELRRSAPGGTPLRRRGPSQLSQDAPAAGALPGM
ITFSQDYVANELTQTFFTITQKIQKKVTGSRNSAELSGMFPLLPGSHLTLNNPALEFVKY
VCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCRDL
DLCKESSFSQDGSVLPQWLCSNCQVAYDTSVIEMALVEALQKKLMAFTLQDLVCLKCRGV
KEANMPVYCSCAGGFALTIHTKVFMEQIGIFQNIAQHYGMSYLMETLEWLLQKGPQLGR
NT seq
6840 nt
NT seq
+upstream
nt +downstream
nt
atggatagagtgatgttcagtgaagacaggatttccctcctcctttcattcagggatgat
ggcccctcttcctctgtctcggctcttaagcgcctggagcgcagtcagtggacggataag
atggattcgcggtttggatttgagaggctcaaggagcccggcgagaagacaggctggctg
gtcaacatgcaccctactgagattttagatgaagacaaacgcttagtcagtgcagtggat
tactactttattcaggatgatgggagcagatttaaggtggccttgccctacaagccatat
ttctacattgcaaccagaaagggttgtgaacgagaagtttcatctttcctctccaagaag
tttcagggtaaaattgctaaagtagagactgtccccaaagaggatctggacttgccaaat
cacttggtgggtttgaagcgaaattacattaagctgtccttcaacaccgtggaggatctt
gtcagagtgaggaaggacgtctcccctgctgtgaagaagaaccgggagcagggccatgcc
agtgatgcgtacacagctatgctctccagtgttctgcaagggggcagtgtggttatcgac
gaagaggaagcctctaagaaggtcaccgaccagctggacaacgttgtggatatgcgagag
tatgacgtgccctaccacatccgcctctccatcgacctgaagatccacgtggctcattgg
tacaacgtcagataccgaggaagtgcctttcctgtggaaatctcccgacgagatgacctt
gttgaacgacccgaccctgtggttttggcatttgacatcgagacgaccaaactgcccctc
aagtttcccgaccctgagaccgaccagattatgatgatttcctatatgattgatggtcag
ggctacctcatcaccaacagggagatcgtttcagacgatgttgaagatttcgagttcacc
cctaagccagagtacgaaggacctttttgtgtcttcaatgaaccagacgagggtcatcta
atccagagatggtttgaacatgtccaggagaccaaacccaccatcatggtcacctacaac
ggggacttttttgactggccgtttgtggaggccagagcagcgatccacggactgagcatg
taccaggagatagggttccagaaggacagccagggggagtacaaggcatcccagtgcatt
cacatggactgtctcaggtgggtgaagagggacagttaccttcctgtgggcagccacaac
ctcaaggcagctgcgaaagccaagctgggctacgaccccgtggagctggaccccgaggac
atgtgccggatggccactgagcagccccagactctggccacgtactcggtgtcggacgcg
gtggccacgtactacctgtacatgaagtacgtccacccctttatcttcgccctctgcacc
atcatccccatggagcctgatgaggtgctgcggaagggctccgggactctgtgtgaggcc
ttgttgatggtgcaggccttccatgccaacatcatcttccccaacaagcaggagcaggag
tttaacaagctgacagacgacggtcatgtgctggactccgagacctacgtgggtggccac
gtggaggccctcgagtcaggcgtgtttcgcagcgacatcccctgccggttcaggatgaat
cctgctgcctttgacttcctgctgcagcgggtggagaagaccatgcgtcacgccatcgag
gaagaggagaaggtgcccatggagcaggtcaccaacttccaagaggtgtgtgatcagatt
aagaccaagctcacctccctgaaagatgttccgaacagaatagagtgtccccttatctac
cacctggatgtgggggccatgtaccccaacatcatcctgacgaaccgtctgcagccgtct
gccgtggtggacgaggccacctgtgctgcctgtgacttcaacaagccgggagcagactgc
cagaggaagatggcctggcagtggaggggcgagttcatgccagccagccgcagcgagtac
catcggatccagcaccagctggagtcggagaagttccctcccttgactgcagagggtccg
ccccgggcctttcacgagctgtcccgcgaggagcaggctaaatacgagaagcggaggctg
tcagattactgccggaaggcgtacaagaagatccacgtgaccagggtggaggagcgcctc
accaccgtctgccagcgggagaactctttctacgtggacacggtgcgcgccttccgagac
aggcgctacgagttcaagggtctccacaaggtgtggaagaagaagctctccgcggccatg
gagctgggcgacgcggccgaggtgaagcgctgcaagaacatggaggtcctgtacgactcg
ctgcagctggcgcacaagtgcatcctcaactccttctacggctacgtcatgcgtagaggg
gcccgctggtactccatggagatggcaggcattgtctgcttcacgggggccaacatcatc
acccaggcacgggagctgatcgaacagatcgggaggcccctggagctggacacagatgga
atatggtgcgtcctgcccaacagcttccctgaaaactttgtcatcaagacggccagtgtg
aaaaagcccaaggtgaccatttcctaccccggggccatgttaaacatcatggtcaaggaa
ggctttaccaacgatcagtaccaggagctgactgagccgtcctcactcacctatgtcacc
cgctcagagaacagcatctttttcgaggttgacggaccgtaccttgccatgatccttcca
gcctccaaggaagaaggcaagaaactgaagaagagatacgccgtcttcaatgaggatggc
tccctggctgagctaaagggcttcgagatcaagcgccgaggggagctgcagctgatcaag
atcttccagtcctccgtgttcgaggccttccttaagggcagcacgctggaagacgtgtac
ggctctgttgccaaggtggctgattactggctggacgtgctgtacagcaaagcagccaac
atgccggattctgagctgtttgagctgatctctgagaaccgctccatgtctcggaagctg
gaagattatggggagcagaagtccacgtctatcagcacagccaagcgcctggctgagttc
ctgggggatcagatggtgaaggacgcggggctgagctgccgctacatcatctcccggaag
cccgaggggtctcccgtcacggagagggccatcccgctagccattttccaggccgagccc
atggtgaggaagcactttctccggaaatggcttaagagttcttcgctccaagactttgat
attcggacgattctggattgggactactacatcgagcgtctggggagtgccatacagaag
atcatcacaatcccggcggctctgcagcaggtgaagaacccagtgccacgcgtcaagcac
cccgactggctgcacaagaagcttctggagaagaacgacgtctgcaagcagaagaagatc
agtgagctctttgtccttgagggcaggagacaggtgggcacggcccgggctccagaaggc
acgcagagccttggtgctcctgacatggaggattttggccttgtgaagccaccgcactcg
gcggttcctgttgccacgaagaggaagcgcatcctctgggagagccaggaggggtcgcag
gacatggagctgacggtgccctggcaggaaatcttggggcagcctccggccctcggaacc
acccaggaagagtggctggtctggctccggttccataagaagaagtggcagctgcaggcc
cggcagcggctggctcgcaagaagaggcggcgtgtggaggtggcggagggcggacctctg
cccggggccgtccgagacaggcccaccaccgggctggggagcttcctgcgaaggactgcc
cgcagcatcttggaccttccgtggcagatcgtgcagatcagtgagaccggccaggcgggg
ctgttcaggctgtgggccgtcatcagcagtgacttgcactgcatccggctgagcatcccc
cgcgtgttctacgtcaaccagcgggtggccaaagccgaggaggggccttcatatcgcaag
gtcagccgcgtccttccacgctccaacatggtctacaacctctatgagtactcggtgccc
gaggacatgtaccaggaacacatcaacgagatcaacaccgagttgtcagccccggacatt
gagggcgtgtacgagactcaggtcccgttactgttccgggccctggtgcagctgggctgt
gtgtgtgtggtcaacaaacagctggtgaggcacctttcaggctgggaggcggagaccttt
gctctcgagcacctggagatgcgctctctggcccagttcagctacctggaaccaggcagc
atccgccacctctacctgtatcatcacgcgcagggccacaaagcgctcttcggcttgttc
gtgccctcccagcgcagagcgtctgtgtttgtgttggacaccgtgcgaagcaaccagatg
cccagcctcagcgctctgtactcagccgagcacagcctcctgatggagagagtgggtcct
gagctcctgcctccccccaaacacactttcgaggttcgggccgaaacggacatgaagacc
atctgcagggccatccagcgctccctgctggcctacaaagaggagcgccgggggcccaca
ctcatcgccgtgcagtccaactgggagctgaagaggctggctagcgaggttcccgtcctg
gaggagttcccgctggtgcctgtccacgtggccgataagatcagctatggagtcctggac
tggcagcgccttggggcccggcgcatgatccgccactacctcaacctcgacacctgtctg
tcacaggccttcgagatgagccggtacttccacatccccattggtaatctgcctgaggac
atctccacctttggctccgacctcttctttgcccgccaccttcagcgccacagccacctg
ctctggctgtcccctacgtcacgccctgacctgggcggcaaggaggccgatgacaatcgc
ctcgtcatggagtttgatgaccaggccagtgtggagatcaactatccaggctgctactct
acggtgtgcgtggagctggacatccagaacctggctgtgaacaccatcctgcagtcccac
catatcaatgacctggaaggggccgacagcgtgggcatcagcttcgatgtgatccagcag
gcctccctggaggacatgatcaccggcaatcaggccgccagcaccctggccagctacgac
gagacagcgctctgctccagcaccttcaggatcctgaagagcatggtggtgggctgggtg
aaagagatcacgcagtaccacaacatctacgccgacaaccaggtgatgcacttctaccgc
tggctgcggtccccgtcctcgctgctccacgaccctgctctgcaccgcacgctccacaac
atgatgaagaagctctttctgcagctcatcgccgagttcaagcgcttggggtcatctgtc
gtctatgccaacttcaaccgcatcgtcctctgcacgagaaagcggcggattgaggacgcc
gttgcctacgtggagtacgtcaccagcagcatccattctaaagagatcttccattccttg
acaatttcattctctcggtgctgggaatttcttctgtggatggatccctccaactatggt
ggaatcaaaggagacgttccatctcgtattcactgtggacagcaagactccccaaaaggg
ggtggagaggaggaagaggaggaggaggaggaggaggaggaggaggaggaggaggaaggc
gcacaggagcccgatgtggaggacaagctggagaacagctggaacatcgtgcaattcctg
ccacaggcggcctcgtgccagagctacttcctcatgatcgtgtcagcctacgtggtggcc
gtgtaccacagcatgaaggaggagctgcggcgcagcgccccagggggcacgcccctgaga
cgccgggggcccagccagctgtcccaggacgccccggcggccggcgcccttcccggaatg
atcaccttctcacaagactacgtggccaacgagctcacacagaccttcttcaccatcact
cagaagattcagaagaaggtcacgggctcgcggaactccgccgagctgtccggcatgttt
ccgctgctccccggttcccacctgacgctcaacaaccctgcgctggagttcgtcaagtac
gtgtgcaaggttctgtctctggacacgaacatcacaaaccaggtgaacaagttgaaccgg
gacctgcttcgcctggtggacgtgggcgagttctcggaggaggcccagttccgagacccc
tgccgttcctacgtgctccctgaggtcatctgccgcagctgtaacttctgccgggacctg
gacctgtgcaaagagtcctccttctctcaggacgggtctgtgctgcctcagtggctctgc
tccaactgtcaggttgcctatgacacctcagtcatcgagatggctctggtggaagccctg
cagaagaagctgatggccttcactctgcaggacctggtctgcctgaagtgccggggtgtg
aaggaggccaacatgcctgtgtactgcagctgtgcggggggcttcgccctcaccatccac
accaaggtcttcatggagcagattggaatcttccagaacatcgcccagcactacggcatg
tcctacctcatggagaccctggagtggctgctgcagaagggccctcagctgggccgttag
DBGET
integrated database retrieval system
