KEGG   Ursus maritimus (polar bear): 103678992
Entry
103678992         CDS       T03271                                 
Name
(RefSeq) cytochrome P450 1A1 isoform X1
  KO
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00140  Steroid hormone biosynthesis
umr00380  Tryptophan metabolism
umr00830  Retinol metabolism
umr00980  Metabolism of xenobiotics by cytochrome P450
umr01100  Metabolic pathways
umr04913  Ovarian steroidogenesis
umr05204  Chemical carcinogenesis - DNA adducts
umr05207  Chemical carcinogenesis - receptor activation
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103678992
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    103678992
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    103678992
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    103678992
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    103678992
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    103678992
   05207 Chemical carcinogenesis - receptor activation
    103678992
   05208 Chemical carcinogenesis - reactive oxygen species
    103678992
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103678992
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:umr00199]
    103678992
Enzymes [BR:umr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     103678992
Cytochrome P450 [BR:umr00199]
 Cytochrome P450, animal type
  CYP1 family
   103678992
SSDB
Motif
Pfam: p450 Gemini_BL1 P116
Other DBs
NCBI-GeneID: 103678992
NCBI-ProteinID: XP_008706707
UniProt: A0A384DI33
LinkDB
Position
Unknown
AA seq 516 aa
MFSVFRLSIPISATELLLASAVFCLVLWVVRAWQPRAPKGLKSPPGPWGWPLLGNVLTLG
KSPHLALSRLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQSDDFKGRPDLYSFTLVT
DGQSMTFNPDSGPVWAARRRLAQNALKSFSTASDPASASSCYLEEHVSKEAEALLSRLQE
QMAEAGRFEPYRYVVVSVANVVCAMCFGKRYDHDDQELLSLVNLSNEFGEAVASGSPVDF
FPILRYLPNPALDVFKDLNKRFYAFTQKLVKEHYRKFEKGHIRDITDSLIEHCRDKRLDE
NANIQLSDEKIVNVVLDIFGAGFDTVTTAISWSLLYLVTNPNVQKKIQEELDIVIGRARQ
PRLSDRPQLPYMEAFILEVFRHASFVPLTIPHSTTRDTSLSGFYIPKGRCVFVNQWQINH
DQKLWGDPSEFRPERFLTLDGTINKTLSEKVILFGMGKRKCIGETIARLEVFLFLAILLQ
QVEFSVPQGTKVDMTPTYGLTMKHARCEHFQVRVRA
NT seq 1551 nt   +upstreamnt  +downstreamnt
atgttctctgtgttcagactctccatccccatctcggccaccgagcttctcctggcctcc
gccgtcttctgcctggtgctctgggtggtcagggcctggcagcctcgggctcccaaaggc
ctgaagagccccccggggccctggggctggcccctgctggggaacgtgctgaccttgggg
aagagcccgcatctggcgctgtcgaggctgagccagcgttatggggacgtgctgcaaatc
cgcatcggctcaacgcccgtgctggtcctcagcggcctggacaccatccggcaggccctg
gtgcggcagagtgatgatttcaagggccggcccgacctctacagcttcactctggtcaca
gatggccagagcatgaccttcaacccagactctggaccagtgtgggctgcccgcaggcgc
ctggcccagaacgccctgaagagtttctccactgcctcggacccggcgtccgcgtcctcc
tgctacctggaggagcacgtgagcaaggaggccgaggccctcctcagcaggctgcaggag
cagatggcagaggcggggcgctttgaaccctacagatacgtagtggtgtcggtggccaat
gtcgtctgtgccatgtgctttggcaaacgctatgaccacgatgaccaagagctgcttagc
ctagtcaacctgagtaacgaattcggggaggcggttgcctctgggagcccggtggacttc
ttccccatcctccgatacctgcccaaccccgccctggatgtcttcaaggacctgaataaa
aggttctatgccttcacgcagaagctggtcaaggaacactacagaaagtttgagaagggc
cacattcgggatatcacagacagcctgatcgagcattgtcgggacaagaggctggatgag
aatgccaatatccagctgtctgacgagaagattgttaatgttgtcttggacatctttgga
gctggatttgacacggtcacaactgccatctcctggagcctcctgtacctggtgacgaac
cccaatgtacagaagaagatccaggaggagctggacatagtgattggcagggcccggcag
ccccggctctccgacagaccccagctgccctacatggaggcattcatcctggaggtcttc
cgacacgcttccttcgtccccctcaccatccctcatagtaccacaagagacacaagtctg
agtggcttttacatccccaagggacgttgtgtctttgtgaaccagtggcagatcaaccat
gaccagaagctatggggtgacccatccgagttccggccagaacgatttctcactctcgat
ggcaccatcaacaagacactgagtgagaaggtgattctcttcggtatgggcaagcggaag
tgcattggtgagaccattgcccgactggaggtctttctcttcctggccatcctgctgcag
caggtggaattcagtgtgccccagggcacgaaggtggatatgacccccacctacgggctg
accatgaagcacgcccgctgtgagcacttccaagtgcgggtgcgcgcttag

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