Ursus maritimus (polar bear): 103679450 Help Entry 103679450         CDS       T03271                                  Symbol CAPN1 Name (RefSeq) calpain-1 catalytic subunit   KO K01367   calpain-1 [EC:3.4.22.52] Organism umr  Ursus maritimus (polar bear) Pathway umr04141   Protein processing in endoplasmic reticulum umr04210   Apoptosis umr04217   Necroptosis umr04218   Cellular senescence umr04382   Cornified envelope formation umr05010   Alzheimer disease umr05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:umr00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     103679450 (CAPN1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     103679450 (CAPN1)    04217 Necroptosis     103679450 (CAPN1)    04218 Cellular senescence     103679450 (CAPN1)  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     103679450 (CAPN1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103679450 (CAPN1)    05022 Pathways of neurodegeneration - multiple diseases     103679450 (CAPN1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:umr01002]     103679450 (CAPN1) Enzymes [BR:umr01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.52  calpain-1      103679450 (CAPN1) Peptidases and inhibitors [BR:umr01002]  Cysteine peptidases   Family C2: calpain family    103679450 (CAPN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh Motif Other DBs NCBI-GeneID:  103679450 NCBI-ProteinID:  XP_040495319 UniProt:  A0A8M1GV04 LinkDB All DBs Position Unknown AA seq 715 aa AA seqDB search MAEEIITPVYCTGVSAQVQKQRAKELGLGRHENAIKYMGQDYEQLRAHCLQSGALFRDEA FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA IASLTLSDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYQGQMVSLIRMRNPWGE VEWTGAWSDGSSEWNSVDPYEREQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS RSIRKWNTMLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDADDDYGGRESGCSF VLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANSSRARSEQFIN LREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQIQANLPDEQVLS EEEIDENFKALFRQLAGEDMEISVKELQTILNRIISKHKDLRTKGFSLESCRSMVNLMDR DGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFRLNKKLYELI ITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA NT seq 2148 nt NT seq  +upstreamnt  +downstreamnt atggctgaggagatcatcacccccgtgtactgcacgggggtgtccgcacaagtgcagaag cagcgggccaaggagctgggccttggccgccatgaaaatgccatcaagtacatgggccag gactatgagcagctgcgggctcattgcctgcagagtggggccctcttccgtgatgaggct ttccccccggtgccccagagcctaggctacaaggacctgggccccaactcctccaaaacc tatggcatcaagtggaaacgtcccacggagctgctctcaaacccccagttcattgtggat ggagccacccgcacagacatctgccagggagcactgggggattgttggctcctggctgcc attgcctccctcaccctcagtgacacgcttctgcatcgagtggtaccacacggccaaagc ttccagaatggctatgccggcatcttccatttccagctgtggcagtttggggaatgggtg gatgtggtcgtggatgacctgctgcccatcaaggacgggaagctggtgtttgtgcactcc gcccaaggcaacgagttctggagtgccctgctcgagaaggcctatgccaaggtgaatggc agctacgaggccctctctgggggcagtacttcagagggcttcgaggacttcacaggcggg gtcaccgagtggtatgagctacgcaaggcacccagcgacctctaccaaatcatcctcaag gccctggagcgggggtccctcctgggctgctccattgacatctccagcgttctggacatg gaggccatcaccttcaagaagctggtgaagggccacgcctactctgtgacaggggccaag caggtgaactaccagggccagatggtgagcctgatccggatgcggaatccctggggcgag gtggagtggacgggagcctggagtgacggctcctcggagtggaacagtgtggacccttac gagcgggagcagctccgggtcaagatggaggatggagagttctggatgtccttccgagac ttcatgcgtgagttcacccgcctggagatctgcaacctgacgcccgacgcgctcaagagc cggtcgatccgcaaatggaacaccatgctctatgaggggacctggcggcgggggagcacc gcgggcggctgccggaactacccagccaccttctgggtcaatccccagttcaagatccgg ctggaggagaccgatgatgcggacgatgactacgggggtcgcgagtcaggctgcagcttc gttctagccctcatgcagaagcaccgtcgccgggagcgccgctttggccgcgacatggag accattggcttcgccgtctacgaggtccctccggagctggtgggccagccggccgtgcac ctgaagcgggacttcttcctggctaactcgtcgcgggcgcgctcggagcagttcatcaac ctgcgtgaggtcagcacgcgcttccgcttgccgcccggggagtatgtggtggtaccctcc actttcgagcccaacaaggagggggacttcgtgctgcgcttcttctccgagaagagcgcc gggacccaggagctggacgaccagatccaggccaatctccccgatgagcaagtgctctca gaagaggagattgacgagaacttcaaggccctcttcaggcagctggccggggaggacatg gagatcagcgttaaggagctgcagaccatcctgaacaggatcatcagcaaacacaaggat ctgcgtaccaagggcttcagcctggagtcgtgccgcagcatggtgaacctcatggaccgg gacggcaacgggaagctgggcctggtggagttcaacatcctgtggaatcgcatccggaat tacctgtccatcttccggaagttcgacttggacaagtcgggcagcatgagtgcctacgag atgcggatggccatcgagtctgcaggcttcaggctcaacaagaagctctatgagctcatc atcacccgctactcggagccggacctggccgtggacttcgacaacttcgtgtgttgcctg gtgcgcctggagaccatgttccggtttttcaaaactctggacacagatctggatggcgtc gtgacctttgacttgtttaagtggttacagctgaccatgtttgcatga

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