KEGG   Ursus maritimus (polar bear): 103679622
Entry
103679622         CDS       T03271                                 
Symbol
NDUFS8
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1
  KO
K03941  NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00190  Oxidative phosphorylation
umr01100  Metabolic pathways
umr04714  Thermogenesis
umr04723  Retrograde endocannabinoid signaling
umr04932  Non-alcoholic fatty liver disease
umr05010  Alzheimer disease
umr05012  Parkinson disease
umr05014  Amyotrophic lateral sclerosis
umr05016  Huntington disease
umr05020  Prion disease
umr05022  Pathways of neurodegeneration - multiple diseases
umr05208  Chemical carcinogenesis - reactive oxygen species
umr05415  Diabetic cardiomyopathy
Module
umr_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    103679622 (NDUFS8)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    103679622 (NDUFS8)
  09159 Environmental adaptation
   04714 Thermogenesis
    103679622 (NDUFS8)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103679622 (NDUFS8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103679622 (NDUFS8)
   05012 Parkinson disease
    103679622 (NDUFS8)
   05014 Amyotrophic lateral sclerosis
    103679622 (NDUFS8)
   05016 Huntington disease
    103679622 (NDUFS8)
   05020 Prion disease
    103679622 (NDUFS8)
   05022 Pathways of neurodegeneration - multiple diseases
    103679622 (NDUFS8)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    103679622 (NDUFS8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103679622 (NDUFS8)
Enzymes [BR:umr01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     103679622 (NDUFS8)
SSDB
Motif
Pfam: Fer4 Fer4_7 Fer4_16 Fer4_21 Fer4_6 Fer4_9 Fer4_8 Fer4_10 Fer4_2 Fer4_4 Fer4_17 Fer4_3
Other DBs
NCBI-GeneID: 103679622
NCBI-ProteinID: XP_040495478
UniProt: A0A8M1GII2
LinkDB
Position
Unknown
AA seq 210 aa
MRCLTTSTLLRALAQAARAGHPTGRSLHSSTVAATYKFVNMREPTMDMKSVTDRAAQTLL
WTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAV
CPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE
LLYNKEKLLSNGDKWEAEIAANIQADYLYR
NT seq 633 nt   +upstreamnt  +downstreamnt
atgcgctgcctgactacgtctacactgcttcgggccctggcccaggctgcacgtgcaggg
catcccaccggccggagcctccacagcagcacagttgcagcgacctacaagttcgtgaac
atgcgggaacctacgatggacatgaagtcggtgaccgaccgggctgctcagaccctgctg
tggactgagctcatccgaggcctgggcatgaccctaagctacctgttccgggagcctgcc
accatcaactacccattcgagaagggcccactgagccctcgctttcggggagagcatgcg
ctgcgtcgctatccatcaggagaggagcgctgcattgcctgtaagctttgtgaggccgtc
tgccccgctcaggccatcaccatcgaggccgagccgcgggccgatggcagccgccggacc
acccgctatgacatcgacatgaccaagtgcatctactgcggcttctgccaggaggcctgc
cccgtggacgccattgtcgagggccccaacttcgagttctccaccgagacgcacgaggag
ctcctgtacaacaaggagaagctgctcagcaacggggacaagtgggaggcggagatcgcc
gccaacatccaggccgactacctgtaccgctga

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