| Entry |
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| Symbol |
VAV2
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| Name |
(RefSeq) guanine nucleotide exchange factor VAV2
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| KO |
| K05730 | guanine nucleotide exchange factor VAV |
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| Organism |
umr Ursus maritimus (polar bear)
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| Pathway |
| umr04650 | Natural killer cell mediated cytotoxicity |
| umr04660 | T cell receptor signaling pathway |
| umr04662 | B cell receptor signaling pathway |
| umr04664 | Fc epsilon RI signaling pathway |
| umr04666 | Fc gamma R-mediated phagocytosis |
| umr04670 | Leukocyte transendothelial migration |
| umr04810 | Regulation of actin cytoskeleton |
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| Brite |
KEGG Orthology (KO) [BR:umr00001]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
103679942 (VAV2)
04024 cAMP signaling pathway
103679942 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103679942 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103679942 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103679942 (VAV2)
04660 T cell receptor signaling pathway
103679942 (VAV2)
04662 B cell receptor signaling pathway
103679942 (VAV2)
04664 Fc epsilon RI signaling pathway
103679942 (VAV2)
04666 Fc gamma R-mediated phagocytosis
103679942 (VAV2)
04670 Leukocyte transendothelial migration
103679942 (VAV2)
04062 Chemokine signaling pathway
103679942 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103679942 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
103679942 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103679942 (VAV2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
839 aa
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHPV
AQNKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMKMGMSEEDKRNCCLLEIQETEAKYYRTLEDIEKNYMTPLRLVLSPADVTAIFINLE
DLIKVHNSFLRAIDVSMMAGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLAGRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEYGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRRGYSYELKEVIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGKQGF
QFFCKTEDMKRRWMEQFEMAMSNIKPDKANANHHNFQMYTFDKTTNCKACRMFLRGTFYQ
GYLCTKCGVGAHKECLEVTPPCKISSPADLDASGAGPGPKMVAVQNYHGNPAPPGKPVLT
FQTGDVIELLRGDPETQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPIGRPPSREIDYTA
YPWFAGNMERQQTDNLLKSHASGTYLIRERTAEAERFAISIKFNDEVKHIKVVEKDSWVH
ITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERAASRASSRSPVFTPRVIG
TAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGEANGRIGWFPSTYVEEEGIQ |
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| NT seq |
2520 nt +upstreamnt +downstreamnt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggcggtggtgttcgacctggcgcaggcgctgcgcgacggc
gtcctcctgtgtcagctcctgcacaacctctcccccggctccatcgacctcaaggacatc
aacttccggccgcagatgtcccagttcctgtgcttgaagaacatccgtaccttccttaaa
gtctgccacgataaatttggactgagaaacagcgagctgtttgacccctttgacctcttc
gatgtccgagactttgggaaggtcatctctgccgtgtccagactctcgctgcaccccgtg
gcacagaacaaagggatcaggccctttccctcggaggagaccgccgagaatgacgacgat
gtctatcgcagcctggaggagctggcggatgagcatgacctgggggaggacatctacgac
tgcgtcccgtgcgaggacgagggcgacgacatctatgaggacattatcaaggtggaggtg
cagcagcccatgaaaatgggcatgtccgaggaagacaagaggaactgctgcttgctggag
attcaggagactgaggccaagtactaccgaaccctggaggacatcgagaagaactacatg
acacccctgaggctggtgctgagcccggcggacgtgacagccatcttcatcaacctggag
gacctgatcaaggtgcataacagcttcctgcgggccatcgacgtgtccatgatggcaggg
ggcagcactctggccaaggtcttcctcgatttcaaggaaaggctcctgatctacggggag
tactgcagccacatggagcacgcccagaacacgctgaaccagctcctcgccggccgggag
gacttcagacagaaggtcgaggaatgcacgctgaaggtccaggacgggaagtttaagctt
caagacctgctcgtggtgcccatgcagagggtcctgaagtaccacctccttctgaaggaa
cttctgagccattccactgatcggcccgagaggcagcagctcaaagaagcgttggaagcc
atgcaggacttagcaatgtacataaacgaagttaaacgggacaaggagaccctgaagaaa
atcagcgaatttcagagttctatagaaaacttgcaagtgaaactggaggaatatgggagg
ccgaagatcgatggggagctgaaggtccggtccatagtcaaccacaccaagcaagatagg
tacttgtttctgttcgacaaggtggtcattgtctgtaagagaagaggctacagctacgag
ctgaaggaggtcatcgagctactcttccacaagatgaccgacgaccccatgaacaacaag
gacgtcaagaagtggtcctacggattctatttaattcatctccaagggaagcagggcttc
cagttcttctgcaagacggaggatatgaagcggaggtggatggaacagttcgagatggcc
atgtccaacatcaagcccgacaaggccaatgccaaccaccacaacttccagatgtacacc
tttgacaagaccaccaactgcaaagcctgcagaatgttcctcaggggcaccttttaccag
ggctacctgtgcaccaagtgtggtgtcggggcgcacaaggagtgtctggaggtgactcct
ccctgcaagatcagttctcctgcagacctggatgcctctggagcaggaccgggtcccaag
atggtggccgtgcagaattaccatggcaacccagctccccccgggaagccagtgctgacc
ttccagacgggcgatgtgatcgagctgctgcgaggcgaccccgagactcagtggtgggag
ggtcggctggtgcaaaccaggaagtcaggctactttcctagctcgtctgtgaagccctgc
cccgtggacggaaggccgcccatcggcaggccgccatcccgggagatcgactacaccgcc
tacccctggtttgcaggcaacatggagagacagcagaccgacaacctgctcaaatcgcac
gccagcgggacctacctaatcagggagcggacggccgaggcagagcgctttgccataagc
atcaagttcaacgacgaggtgaaacacatcaaggtggtggagaaggacagctgggtccac
atcacggaagccaagaaatttgaaagcctcttggaactggtagagtactatcagtgccac
tcactcaaggagagcttcaagcagctggacaccacgctcaagtacccctacaagtccagg
gagcgcgcagcctccagggcctccagccggtccccagtgttcacgccccgtgtcattggc
acggccgtggccaggtacaacttcgccgcccgagacatgcgggagctctcgctgcgggaa
ggcgacgtggtgaagatctacagtcgcattggtggggaccagggctggtggaagggcgag
gccaacggacggatcggctggtttccttcaacatacgtagaggaggagggcatccagtga |
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