Ursus maritimus (polar bear): 103680018
Help
Entry
103680018 CDS
T03271
Symbol
FLT4
Name
(RefSeq) vascular endothelial growth factor receptor 3
KO
K05097
FMS-like tyrosine kinase 4 [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04014
Ras signaling pathway
umr04015
Rap1 signaling pathway
umr04020
Calcium signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr05200
Pathways in cancer
umr05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103680018 (FLT4)
04014 Ras signaling pathway
103680018 (FLT4)
04015 Rap1 signaling pathway
103680018 (FLT4)
04020 Calcium signaling pathway
103680018 (FLT4)
04151 PI3K-Akt signaling pathway
103680018 (FLT4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103680018 (FLT4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103680018 (FLT4)
09162 Cancer: specific types
05224 Breast cancer
103680018 (FLT4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103680018 (FLT4)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103680018 (FLT4)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
103680018 (FLT4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
Ig_2
Pkinase
I-set
ig
VEGFR-2_TMD
Ig_VEGFR-1-like_5th
V-set
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
C1-set
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
103680018
NCBI-ProteinID:
XP_040478648
UniProt:
A0A8M1F5E6
LinkDB
All DBs
Position
Unknown
AA seq
1409 aa
AA seq
DB search
MGLAPPLGGKGSRPGPAPPAPGPSPARARSVRPHSEPRAAAAQVGPAPQRPEMQRGAALC
LRLWLWLGLLDGERGLASGYSMTPPTLNITEETHVIDSSDSLSISCRGQHPLEWSWPGAQ
EAPATGEKDGEDTGVVQDCEGTDTRPYCKVLLLREARANDTGSYRCYYKYIQARIEGTTA
ASTYVFVRDVGQPFINKPDTLLVNRKDSTWVPCLVSIPGLNVTLRSQNSALRPDGQEVVW
DDRRGMRVPTPLLRDALYLQCETTWGGQDFLSNPFLVHITGNELYDIQLFPKKSLELLVG
EKLVLNCTVWAEFNSGVTFNWDYPGKQAERGKWVPERRSQQTHTELSSILTIHNVSQHDL
GPYVCEANNGIQRFRESTEVIVHEKPFISVEWLKGPVLEATAGDELVKLPVKLAAYPPPE
FQWYKDRKSVSGRQSPHALVLKEVTEASAGIYTLALWNSAAGLRRNISLELVVNVPPHIH
EKEASSPSTYSRHSRQALTCTAYGVPPPLSIQWHWRPWTPCKAFTQRSLRRQQRDHMPQC
RDWREVTTQDAVNPIESLDTWTEFVEGKNKTVSKLVIQNANVSAMYKCVVFNKVGQDERL
IYFYVTNIPDGFSIKSEPSEEPLEGQDVRLSCRADNYTYEHLRWYRLNLSTLHDAHGNPL
MLDCKNVHLFATPLAAHLEEAEPGARHATLSLTIPSVAPEHEGDYVCEVQDRRSHDKHCH
KKYLSVQALEAPRLTQNLTDLLVNVSDSLEMRCPVAGAHVPSILWYKDERLLEEESGIDL
ADSNQKLSIQRVREEDAGRYLCSVCNAKGCVNSSASVAVEGSEDKGSMEIVILVGTGVIA
VFFWVLLLLIFCNMRRPAHADIKTGYLSIIMDPGEVPLEEQCEYLSYDASQWEFPRERLH
LGRVLGHGAFGKVVEASAFGIHKGSSCDTVAVKMLKEGATASEHRALMSELKILIHIGNH
LNVVNLLGACTKPNGPLMVIVEFCKYGNLSNFLRAKREAFSPYAEKSPEQRRRFRAMVEG
AIADRRRPGSSERALLSRLLMGKGGAERAPPAQEAQDLWLSPLTMEDLVCYSFQVARGME
FLASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDYVRKGSARLPLKWMAPESI
FDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKEGTRMRAPELATPTIRS
VMLSCWSGDPKERPAFSELVEILGDLLQGGGRQEEEEDCMAPCSSQSLEDGSFLQASTTA
LHVAEADTEDSPPSLHRHSLAARYYNCVSFPGCLARGTQTQGSSRMKTFEEFPMTPTTYK
ASVDNQTDSGMVLASEEFEQLESSCKGPGRNVDVTRAYSDTQGRRRRLDRGARGGQVFYN
SEYGELAGPQDEGDCTPSARAPFFTDDSY
NT seq
4230 nt
NT seq
+upstream
nt +downstream
nt
atgggcctggccccgccccttggggggaaggggtcccgcccaggccccgccccgcccgcg
ccgggccccagccccgcccgcgctcgctctgtgcgcccacactccgagccccgagcggct
gccgcgcaggtcggacccgcgccgcagcggccggagatgcagcggggagccgcgctgtgc
ctgcgcctgtggctctggctcggactgctcgacggcgagcgcggcctggcgagtggctac
tccatgacccccccaaccctaaacatcacagaagagacacacgtcatcgactccagtgac
agcctgtccatctcctgcagggggcagcaccccctcgagtggtcctggccaggggctcag
gaggcaccggccacaggggagaaggacggcgaggacacaggagttgtgcaagactgcgag
ggcacggacaccaggccctactgcaaggtgctgctgctgcgcgaggcccgcgccaacgac
acgggcagctaccgctgctactacaagtacatccaagcccgcatagagggcaccacagcc
gccagcacctacgtgttcgtgagagacgtggggcagccattcatcaacaagccagacacg
ctcctggtcaacaggaaggattccacgtgggtgccctgcctggtgtccatccccggcctc
aacgtcacgctgcgatcgcaaaactcggcactgcggcctgatgggcaggaggtggtgtgg
gacgaccgtcgtggcatgcgtgtgcccacaccgctgctgcgcgatgccctgtacctgcag
tgtgagaccacctggggtggccaagacttcctctccaaccccttcctcgtgcacatcaca
ggcaacgagctctatgacatccagctgttccccaagaagtcgctggagctgctggtcggg
gagaagctggtcctaaactgcactgtgtgggctgagttcaactcaggtgtcaccttcaac
tgggactatccagggaagcaggcagagcggggtaagtgggtgccggagcggcgctcccag
cagactcacacagagctctccagcatcctgaccatccacaacgtcagccagcacgacctg
ggcccatacgtgtgcgaggccaacaacggcatccagcgattccgggagagcaccgaggtc
atcgtgcatgaaaagcccttcatcagcgtcgagtggctcaagggtcctgtcctggaggcc
acagcaggagacgagctggtgaagctgcccgtgaagctagcggcgtaccccccgccggag
ttccaatggtacaaggacagaaagtcagtgtccgggcgccagagtccgcacgccctggtg
ctcaaggaggtgacggaggccagtgcgggcatctacaccctcgccctgtggaactctgcg
gctggactacggcgaaacatcagcctcgagctggtggtaaacgtgcccccccacatccac
gagaaggaggcctcctcccccagcacctactcccgccacagtcgccaggccctcacctgc
actgcctacggggtgccccctcctctcagtatccagtggcactggcggccgtggactccc
tgcaaggccttcacccagcgcagcctccggcggcagcagagagatcacatgccacagtgc
cgggactggagagaggtgaccacgcaagatgctgtgaaccccatcgagagcctggacacc
tggactgagtttgtggaggggaagaataagacggtgagcaagctggtgatccagaatgcc
aacgtgtccgccatgtacaagtgtgtggtcttcaacaaagtgggccaggacgagcggctc
atctacttctacgtgaccaacatccccgatggcttcagcataaaatccgagccatcggag
gagccgctagagggccaggacgtgcgcctgagctgccgggcagacaactacacctacgag
catctgcgttggtaccgcctcaacctgtccacgctgcacgacgcgcacgggaacccgctg
atgctcgactgcaagaacgtgcacttgttcgctacgcctctggccgcccacctggaggag
gcggagccaggggcgcgccacgccacgctcagcctgaccatccccagcgtggcgcctgag
cacgaaggcgactatgtatgcgaggtgcaggaccgtcgcagccacgacaagcactgccac
aagaagtacctgtcagtgcaggccctggaagccccgcggctcacgcagaacttgactgac
ctcctggtgaacgtgagcgactccctggagatgcggtgcccagtggccggggcgcacgtg
cccagtatcttgtggtacaaagatgagaggctgctggaggaagagtctggaatcgacctg
gcagactccaaccagaagctgagcatacagcgcgtgcgcgaggaggacgcgggccgctac
ctgtgcagcgtgtgcaacgcaaagggctgcgtcaactcctctgccagcgtggccgtggaa
ggttccgaggataaaggcagcatggagatcgtgatccttgtcggcaccggggtcatcgct
gtcttcttctgggtcctcctcctcctcatcttctgtaacatgaggaggccagcccacgca
gacatcaagacgggctacctgtccatcatcatggaccccggggaggtgcctctggaggag
cagtgtgaatacctatcatatgatgccagccagtgggagttcccccgggagcggctgcac
ctcgggagagtcctcggccatggggccttcgggaaggttgtggaagcttcggcttttgga
atccacaagggcagtagctgcgacactgtggctgtgaaaatgctgaaagagggcgccaca
gctagcgagcatcgagccttgatgtccgagctcaagatcctaatccacatcggtaaccac
ctcaacgtggtcaacctcctgggggcgtgcaccaagcccaatggccccctcatggtgatc
gtggagttctgcaagtacggcaatctctccaacttcttgcgtgccaagcgggaggccttc
agcccctatgcggagaagtcccctgagcagcgaaggcgctttcgcgccatggtggaagga
gccatagctgaccggaggaggccaggaagcagcgagagggccctcctctcccggctcctg
atgggcaagggcggggcagagcgggcccctccggcccaagaagcccaggacctgtggctg
agcccactgaccatggaggacctcgtctgctacagctttcaggtggcccgaggcatggag
ttcctggcctcccgcaagtgcatccacagagacctggctgctcggaacatcttgctgtca
gaaagcgatgtggtgaagatctgtgacttcggcctggcccgtgacatctacaaagacccc
gactacgtgcgcaagggcagtgcccggctgcccctgaagtggatggcccccgagagcatc
tttgacaaggtgtacaccacacagagtgacgtctggtcctttggggtgctgctctgggag
atcttctccctgggggcctccccctacccgggggtgcagatcaacgaggagttctgccag
cggctgaaagagggcacacggatgcgagccccagagctggccactcccaccatacgcagc
gtcatgctgagctgctggtcaggagaccccaaggagaggcctgcgttctcagagctggtg
gagatcctgggggacctgctgcagggcgggggccgacaggaggaggaggaggactgcatg
gccccctgcagctctcagagcttggaggacggcagcttcttgcaggcgtccaccacagcc
ctgcacgtggccgaggccgacaccgaggacagcccgccgagcctgcaccggcacagcctg
gccgccagatactacaactgtgtgtcctttccggggtgcctggccagagggactcagacc
cagggctcctccaggatgaaaacgttcgaagaatttcccatgaccccgacgacctataag
gcctcggtggataaccagacggacagtgggatggtcctggcctccgaggagtttgagcag
ttggagagcagctgtaaaggaccgggccggaacgtggatgtgaccagggcgtactctgac
acccaagggcggcggcggcggctggaccggggggcacggggagggcaggtgttctacaac
agcgagtacggggagctggcggggccgcaggacgagggcgactgcaccccgtccgcccgc
gcacccttcttcacagacgacagttactga
DBGET
integrated database retrieval system
