Ursus maritimus (polar bear): 103681714 Help Entry 103681714         CDS       T03271                                  Symbol VAV1 Name (RefSeq) proto-oncogene vav isoform X1   KO K05730   guanine nucleotide exchange factor VAV Organism umr  Ursus maritimus (polar bear) Pathway umr04015   Rap1 signaling pathway umr04024   cAMP signaling pathway umr04062   Chemokine signaling pathway umr04510   Focal adhesion umr04650   Natural killer cell mediated cytotoxicity umr04660   T cell receptor signaling pathway umr04662   B cell receptor signaling pathway umr04664   Fc epsilon RI signaling pathway umr04666   Fc gamma R-mediated phagocytosis umr04670   Leukocyte transendothelial migration umr04810   Regulation of actin cytoskeleton umr05135   Yersinia infection umr05205   Proteoglycans in cancer umr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103681714 (VAV1)    04024 cAMP signaling pathway     103681714 (VAV1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103681714 (VAV1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103681714 (VAV1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     103681714 (VAV1)    04660 T cell receptor signaling pathway     103681714 (VAV1)    04662 B cell receptor signaling pathway     103681714 (VAV1)    04664 Fc epsilon RI signaling pathway     103681714 (VAV1)    04666 Fc gamma R-mediated phagocytosis     103681714 (VAV1)    04670 Leukocyte transendothelial migration     103681714 (VAV1)    04062 Chemokine signaling pathway     103681714 (VAV1)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     103681714 (VAV1)   09171 Infectious disease: bacterial    05135 Yersinia infection     103681714 (VAV1)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103681714 (VAV1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RhoGEF SH3_1 SH3_2 CAMSAP_CH CH SH2 SH3_9 C1_1 PH CDC24 C1_2 LZ3wCH Motif Other DBs NCBI-GeneID:  103681714 NCBI-ProteinID:  XP_008709516 UniProt:  A0A384DR31 LinkDB All DBs Position Unknown AA seq 845 aa AA seqDB search MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREV NLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPI AQNKGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRT EPMPMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDIEIIFINI EDLLRVHTHFLKEMKEALAAPGAPTLYQVFIKYKERFLLYGRYCSQVESASKHLDRVAAA REDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAAEKESLRLAL DAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKM DRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRENKKWTHMFLLIEDQGAQ GYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTF YQGYRCHRCRAPAHKECLGRVPPCGRYGQDLSGTMKKDKPHRRVQDKKRNELGLPKMEVC QEYYGLPPPPGAFGPFLRLNPGDIVELTKAEAEQNWWEGRNTATNEVGWFPCNRVKPYVH GPPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQRVKDTAEFAISIKYNVEVKHIKI MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRAISKPPAGS TKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPSNYVEED YSEYC NT seq 2538 nt NT seq  +upstreamnt  +downstreamnt atggagctgtggcgccagtgtacccactggctcatccagtgccgggtgctgccgcccagc caccgtgtgacctgggaaggggcccaggtgtgcgagctggcacaggccctccgggatggc gtccttctgtgccagttgctcaacaacctgctgccccatgccatcaacctgcgtgaggtc aacctgcgcccccagatgtcccagttcctgtgccttaagaacatccgtaccttcttgtct acctgctgcgagaagtttggcctcaaacggagtgaactttttgaggcctttgacctcttc gatgtgcaggattttgggaaggtcatctacaccctgtctgctctgtcctggaccccgatt gcccagaataaggggatcatgcccttccccactgaggaggagagtgtgggtgatgaagac atctacagcggcctgtctgaccagattgatgacacggtggaggaggatgaggacctgtac gactgcgtggagaacgaggaggcggagggtgacgagatctatgaagacctcatgcgcacg gagcccatgcccatgccgcccaagatgacagagtatgacaagcggtgctgctgcttgcgg gagatccagcagacggaggagaagtatacggacacgctaggctccatccaacagcacttc atgaagcccctgcagcggttcctcaaacctcaagacattgagatcatcttcatcaacatc gaggacctgcttcgcgtacacactcacttcctaaaggagatgaaagaagccctggccgcc ccaggcgcacccactctctaccaggtcttcatcaaatacaaggagaggttcctcctctat ggccgctactgcagccaggtggagtcggccagcaagcacctggaccgtgtggctgcagcc cgggaggatgtgcagatgaagctggaggaatgttctcagcgagcgaacaatgggaggttc accctgcgggacctgctgatggtgcccatgcagcgggtgctcaaataccacctccttctg caggagctggtcaaacacacgcaggatgcagcggagaaggagagcctgcggctggccttg gatgccatgagggacctggcacagtgtgtgaacgaggtcaaacgggacaatgaaacgctg cggcagatcaccaacttccagttgtccatcgagaacctggaccagtctctggcccactat ggccggcccaagatcgatggggagctcaagatcacctcagtggagcggcgctccaagatg gacaggtacgccttcctgctcgacaaagctctgctcatctgtaagcggcgaggggactcc tacgacctcaaggacttcgtgaacctgcacagcttccaggttcgagatgactcctctgga gatcgagaaaacaagaagtggactcacatgtttctcctgatcgaggaccaaggtgcccag ggctatgagctgttcttcaagacgcgagaactgaagaagaagtggatggagcagttcgag atggccatctccaacatctaccctgaaaacgctactgccaacgggcatgacttccagatg ttctcctttgaggagaccacgtcgtgcaaggcttgccagatgctgcttagaggcaccttc tatcaggggtaccgttgtcatcggtgccgggcacctgcacacaaggagtgtctgggaagg gtccctccgtgtggccgatatgggcaagatctttcaggaactatgaagaaggataagcca catcgccgggttcaggacaaaaagaggaatgagctaggcctgcccaagatggaggtgtgt caggagtactatgggcttcctccaccccctggagcctttggaccttttctacggctcaac cctggagacatcgtggagctcaccaaggctgaggccgaacagaactggtgggagggcagg aatacggctaccaatgaagttggctggtttccctgtaacagagtcaagccctatgtgcat ggtccccctcaggacctgtccgttcatctctggtacgctggccccatggagcgcgcgggg gcggaaagtatcctcaccaaccgctcggatgggacgttcttggtgcggcagagggtgaag gacaccgcagaatttgccatcagcatcaagtataatgttgaggtcaagcatattaaaatc atgacagcggaaggactataccggattacggagaagaaggctttccgggggctgacggag ctggtggagttttaccagcagaattccctaaaggactgcttcaagtcgctggacaccacc ctgcagttccccttcaaggagcctgagaagagagccatcagcaaaccaccagcagggagc accaaatattttggcacagccaaagcacgctatgacttctgtgcccgggaccgatcagag ctgtccctcaaggagggtgacatcatcaagatccttaacaagaaggggcaacaaggctgg tggcgaggggagatctatggccgggttggctggttcccctccaactacgtggaggaggat tattctgaatactgctga

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