KEGG   Ursus maritimus (polar bear): 121099769
Entry
121099769         CDS       T03271                                 
Symbol
INS
Name
(RefSeq) insulin
  KO
K04526  insulin
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04014  Ras signaling pathway
umr04015  Rap1 signaling pathway
umr04022  cGMP-PKG signaling pathway
umr04066  HIF-1 signaling pathway
umr04068  FoxO signaling pathway
umr04072  Phospholipase D signaling pathway
umr04114  Oocyte meiosis
umr04140  Autophagy - animal
umr04150  mTOR signaling pathway
umr04151  PI3K-Akt signaling pathway
umr04152  AMPK signaling pathway
umr04211  Longevity regulating pathway
umr04213  Longevity regulating pathway - multiple species
umr04810  Regulation of actin cytoskeleton
umr04910  Insulin signaling pathway
umr04911  Insulin secretion
umr04913  Ovarian steroidogenesis
umr04914  Progesterone-mediated oocyte maturation
umr04917  Prolactin signaling pathway
umr04923  Regulation of lipolysis in adipocytes
umr04930  Type II diabetes mellitus
umr04931  Insulin resistance
umr04932  Non-alcoholic fatty liver disease
umr04940  Type I diabetes mellitus
umr04950  Maturity onset diabetes of the young
umr04960  Aldosterone-regulated sodium reabsorption
umr05010  Alzheimer disease
umr05215  Prostate cancer
umr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121099769 (INS)
   04014 Ras signaling pathway
    121099769 (INS)
   04015 Rap1 signaling pathway
    121099769 (INS)
   04066 HIF-1 signaling pathway
    121099769 (INS)
   04068 FoxO signaling pathway
    121099769 (INS)
   04072 Phospholipase D signaling pathway
    121099769 (INS)
   04022 cGMP-PKG signaling pathway
    121099769 (INS)
   04151 PI3K-Akt signaling pathway
    121099769 (INS)
   04152 AMPK signaling pathway
    121099769 (INS)
   04150 mTOR signaling pathway
    121099769 (INS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121099769 (INS)
  09143 Cell growth and death
   04114 Oocyte meiosis
    121099769 (INS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    121099769 (INS)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    121099769 (INS)
   04910 Insulin signaling pathway
    121099769 (INS)
   04923 Regulation of lipolysis in adipocytes
    121099769 (INS)
   04913 Ovarian steroidogenesis
    121099769 (INS)
   04914 Progesterone-mediated oocyte maturation
    121099769 (INS)
   04917 Prolactin signaling pathway
    121099769 (INS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    121099769 (INS)
  09149 Aging
   04211 Longevity regulating pathway
    121099769 (INS)
   04213 Longevity regulating pathway - multiple species
    121099769 (INS)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    121099769 (INS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121099769 (INS)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    121099769 (INS)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    121099769 (INS)
   04940 Type I diabetes mellitus
    121099769 (INS)
   04950 Maturity onset diabetes of the young
    121099769 (INS)
   04932 Non-alcoholic fatty liver disease
    121099769 (INS)
   04931 Insulin resistance
    121099769 (INS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:umr04052]
    121099769 (INS)
Cytokines and neuropeptides [BR:umr04052]
 Neuropeptides
  Neuropeptides (Unclassified)
   121099769 (INS)
SSDB
Motif
Pfam: Insulin Ins_beta
Other DBs
NCBI-GeneID: 121099769
NCBI-ProteinID: XP_040495583
UniProt: A0A8M1GIS7
LinkDB
Position
Unknown
AA seq 109 aa
MALWTRLLPLLALLAFWAPVPARTFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVED
LPVRDARPEGVPGADPQPRALAGALQRRGIVEQCCTSICSLYQLENYCN
NT seq 330 nt   +upstreamnt  +downstreamnt
atggccctctggacgcgcctcctgcccctgctggctttgctggccttctgggcacctgtg
cccgccagaaccttcgtgaaccagcacctgtgtggctcccacctggtggaggcgctctac
ctggtgtgcggggagcgaggcttcttctacacgcccaaggcccgccgggaggtggaggac
ctgccggtgagggacgccaggccggaaggggtgcctggcgcagacccgcagccccgggcc
ctggcgggggcgctgcagaggcggggcatcgtggagcagtgctgcaccagcatctgctcg
ctctaccagctggagaattactgcaactag

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