KEGG   Ursus maritimus (polar bear): 121103675
Entry
121103675         CDS       T03271                                 
Symbol
SOCS1
Name
(RefSeq) suppressor of cytokine signaling 1
  KO
K04694  suppressor of cytokine signaling 1
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04120  Ubiquitin mediated proteolysis
umr04380  Osteoclast differentiation
umr04630  JAK-STAT signaling pathway
umr04910  Insulin signaling pathway
umr04917  Prolactin signaling pathway
umr04930  Type II diabetes mellitus
umr04935  Growth hormone synthesis, secretion and action
umr05145  Toxoplasmosis
umr05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    121103675 (SOCS1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    121103675 (SOCS1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    121103675 (SOCS1)
   04917 Prolactin signaling pathway
    121103675 (SOCS1)
   04935 Growth hormone synthesis, secretion and action
    121103675 (SOCS1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121103675 (SOCS1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    121103675 (SOCS1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    121103675 (SOCS1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    121103675 (SOCS1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:umr04121]
    121103675 (SOCS1)
Ubiquitin system [BR:umr04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     121103675 (SOCS1)
SSDB
Motif
Pfam: SH2 SOCS_box SH2_1
Other DBs
NCBI-GeneID: 121103675
NCBI-ProteinID: XP_040490477
UniProt: A0A8M1G769
LinkDB
Position
Unknown
AA seq 214 aa
MVAHNQVAADNAISTAAESRRRPEPSSSSSSSPAAPAAPARPRPCPAVPAPAPGDTHFRT
FRSHAEYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSV
KMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQEL
CRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI
NT seq 645 nt   +upstreamnt  +downstreamnt
atggtagcacacaaccaggtggcagccgacaatgcaatctccacggcagcagagtcccga
cggcggccagagccttcttcgtcttcgtcctcgtccccggcggcgcccgcggcccccgcg
cgcccgcggccctgcccggcggtcccggccccggcccccggcgacacgcacttccgcacg
ttccgctcgcacgccgagtaccggcgcatcacccgggccagcgcgctcctcgacgcctgc
ggcttctactgggggcccctgagcgtgcacggggcgcacgagcggctgcgcgccgagccc
gtgggcaccttcctggtgcgcgacagccgccagcggaactgcttcttcgccctcagcgtg
aagatggcctcgggccccacgagcatccgcgtgcacttccaggccggccgcttccacctg
gacggcagccgcgagagcttcgactgcctcttcgagctgctggagcactacgtggcggcg
ccgcgccgcatgctcggggccccgctgcgccagcgccgcgtgcggccgctgcaggagctg
tgtcgccagcgcatcgtggccaccgtgggccgcgagaacctggcgcgcatccccctcaac
cccgtcctccgcgactacttaagctcctttcccttccaaatctga

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