Ursus maritimus (polar bear): 121106331 Help Entry 121106331         CDS       T03271                                  Symbol FZD8 Name (RefSeq) frizzled-8   KO K02375   frizzled 5/8 Organism umr  Ursus maritimus (polar bear) Pathway umr04150   mTOR signaling pathway umr04310   Wnt signaling pathway umr04390   Hippo signaling pathway umr04550   Signaling pathways regulating pluripotency of stem cells umr04916   Melanogenesis umr04934   Cushing syndrome umr05010   Alzheimer disease umr05022   Pathways of neurodegeneration - multiple diseases umr05165   Human papillomavirus infection umr05200   Pathways in cancer umr05205   Proteoglycans in cancer umr05217   Basal cell carcinoma umr05224   Breast cancer umr05225   Hepatocellular carcinoma umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     121106331 (FZD8)    04390 Hippo signaling pathway     121106331 (FZD8)    04150 mTOR signaling pathway     121106331 (FZD8)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     121106331 (FZD8)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     121106331 (FZD8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121106331 (FZD8)    05205 Proteoglycans in cancer     121106331 (FZD8)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     121106331 (FZD8)    05226 Gastric cancer     121106331 (FZD8)    05217 Basal cell carcinoma     121106331 (FZD8)    05224 Breast cancer     121106331 (FZD8)   09172 Infectious disease: viral    05165 Human papillomavirus infection     121106331 (FZD8)   09164 Neurodegenerative disease    05010 Alzheimer disease     121106331 (FZD8)    05022 Pathways of neurodegeneration - multiple diseases     121106331 (FZD8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     121106331 (FZD8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:umr04030]     121106331 (FZD8) G protein-coupled receptors [BR:umr04030]  Frizzled / Smoothened family   121106331 (FZD8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Motif Other DBs NCBI-GeneID:  121106331 NCBI-ProteinID:  XP_040501435 UniProt:  A0A8M1H1M9 LinkDB All DBs Position Unknown AA seq 696 aa AA seqDB search MEWSYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGS GHGRPPGARPPSRGRGGGGGDAGAPPTRGGGGGGKARPPGGGSAPCEPGCQCRAPMVSVS SERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGTAGAGGAAAAAAA GAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILS LTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSL DNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGGPTKTHKLEKLMIRLGLFTV LYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGI TSGVWVWSGKTLESWRALCTRCCWASKGATGGGGAGAAAAGGAGGPGGGGGVGSGGGGGP GGGAGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV NT seq 2091 nt NT seq  +upstreamnt  +downstreamnt atggagtggagttacctgttggaagtgacctcgttgctggccgccttggcgctgttgcag cgctcgagcggcgcggcggctgcctcggccaaggagctggcgtgccaagagattaccgtg ccgctttgcaagggcatcggctacaactacacatacatgcctaaccagttcaaccacgac acgcaggacgaggcgggcctggaggtgcaccagttctggccgctggtagagattcagtgc tcgccggacctcaagttcttcctgtgcagcatgtacacgcccatctgcctggaggactac aagaagcccctgcctccttgccgctcggtgtgcgagcgcgccaaggccggctgcgcaccc ctcatgcgccagtacggctttgcctggcccgaccgcatgcgctgcgaccggctgccggag cagggcaaccccgacacgctgtgcatggactacaaccgcacggacctcaccacagccgca ccgagtccaccgcgccgcctgccgccgccgcctccgggtgagcagccgccctctggcagc ggccacggccgcccgccgggggccaggcccccgtcccgcggcaggggcggtggcggcggg gacgcaggggcgccccccacgcgcggcggcggtggcggcgggaaggcgcggccccctggc ggcggctcagcgccctgcgagccgggctgccagtgccgcgcgcccatggttagcgtgtcc agcgagcggcacccgctctacaaccgcgtcaagaccggccagatcgccaactgcgcgctg ccctgccacaaccccttcttcagccaggacgaacgcgcgttcaccgtcttctggatcggc ctgtggtctgtgctgtgcttcgtgtccaccttcgccaccgtctccaccttcctcatagac atggagcgcttcaagtatcccgagcggcccattatctttctttcggcctgctacctcttc gtgtcagtcggctacctggtacgcctggtggcgggccacgagaaggtggcgtgcagcggc ggcgcgccgggcgcgggcggcacggcaggcgcgggcggcgcggcggcggcggcagcggcg ggcgcgggcgctgcgggcgctggagcaggcggcccgggcgggcgcggcgagtacgaggag ctgggcgctgtggagcagcacgtgcgctacgagaccacggggccggcgctgtgcaccgtg gtcttcttgctcgtctacttcttcggcatggccagctccatctggtgggtgatcctgtcg ctcacgtggttcctggcggcgggcatgaaatggggcaacgaggccatcgccggctactcg cagtacttccacctggccgcgtggctcgtgcccagcgtcaagtctatcgccgtgctggcg ctcagctccgtggacggcgacccggtggctggcatctgctacgtgggcaaccagagcctc gacaacctgcgcggcttcgtgctggcgccgctcgtcatctacctcttcattggcaccatg ttcctgctggccggcttcgtgtcgctcttccgcatccgctcggttatcaaacagcagggc ggccccaccaagacgcacaaactggagaagctcatgatccgcctgggtctcttcaccgtg ctctacaccgtgcccgccgccgtcgtggtcgcctgcctcttctatgagcagcacaaccgc ccgcgctgggaggccacgcacaactgtccgtgcctacgggacctgcagccagaccaggcg cgccggccggactacgccgtcttcatgctcaagtacttcatgtgcctcgtggtgggcatc acctcgggcgtgtgggtctggtccggcaagacgctcgagtcgtggcgtgccctgtgcacc cgctgctgctgggccagcaagggcgccactgggggcgggggcgcgggcgccgcggccgca gggggcgccgggggacccgggggtggtgggggcgtggggtccggtgggggcgggggcccg ggcggtggggcgggatccctctacagcgacgtcagtaccggcctgacgtggcgatctggc acggccagctccgtgtcttatccaaagcagatgccattgtcccaggtctga

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