Ursus maritimus (polar bear): 804864 Help Entry 804864            CDS       T03271                                  Symbol COX1, KEC42_p11 Name (RefSeq) cytochrome c oxidase subunit I   KO K02256   cytochrome c oxidase subunit 1 [EC:7.1.1.9] Organism umr  Ursus maritimus (polar bear) Pathway umr00190   Oxidative phosphorylation umr01100   Metabolic pathways umr04260   Cardiac muscle contraction umr04714   Thermogenesis umr04932   Non-alcoholic fatty liver disease umr05010   Alzheimer disease umr05012   Parkinson disease umr05014   Amyotrophic lateral sclerosis umr05016   Huntington disease umr05020   Prion disease umr05022   Pathways of neurodegeneration - multiple diseases umr05208   Chemical carcinogenesis - reactive oxygen species umr05415   Diabetic cardiomyopathy Module umr_M00154   Cytochrome c oxidase Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     804864 (COX1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     804864 (COX1)   09159 Environmental adaptation    04714 Thermogenesis     804864 (COX1)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     804864 (COX1)   09164 Neurodegenerative disease    05010 Alzheimer disease     804864 (COX1)    05012 Parkinson disease     804864 (COX1)    05014 Amyotrophic lateral sclerosis     804864 (COX1)    05016 Huntington disease     804864 (COX1)    05020 Prion disease     804864 (COX1)    05022 Pathways of neurodegeneration - multiple diseases     804864 (COX1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     804864 (COX1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     804864 (COX1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:umr03029]     804864 (COX1) Enzymes [BR:umr01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.9  cytochrome-c oxidase      804864 (COX1) Mitochondrial biogenesis [BR:umr03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Cytochrome c oxidase     804864 (COX1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  COX1 Motif Other DBs NCBI-GeneID:  804864 NCBI-ProteinID:  NP_597983 UniProt:  Q8SJH3 LinkDB All DBs Position MT AA seq 514 aa AA seqDB search MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGALLGDDQIYNVVVTA HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAMSQYQ TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNNTWAKIHFMIMFIG VNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVMLMIFMIWEAFASKR EVAVVELTSTNIEWLHGCPPPYHTFEEPAYVTLK NT seq 1545 nt NT seq  +upstreamnt  +downstreamnt atgttcataaaccggtgattattctctacgaaccataaagacattggcaccctttatctt ctgttcggtgcatgagccggaatagtgggcactgccctcagccttttaattcgtgccgag ctgggtcagcccggggctctgttgggggatgatcagatctacaatgtagtcgtaactgcc catgcattcgtgataatcttcttcatagttatgcctattataattgggggattcgggaac tgattagtgcctttgatgatcggtgcccccgacatagcgttccctcgaataaataacata agcttctggttgctgccaccatctttcttactgcttctggcctcctctatggtagaagca ggtgcagggactggatgaactgtctaccctcctctagcgggtaatctggcccatgcagga gcatcagtagacttaacaatcttttctctgcacctagcaggcatctcttctattctgggg gctatcaatttcatcactactattattaacatgaaaccccctgcaatatctcaatatcaa acccctctgtttgtatgatcagtcctaatcacagcagtacttcttcttttatctctgcca gtcttagcagctgggattactatactacttacagatcgaaaccttaacactacctttttt gatccagctggaggaggagatcctattttatatcaacacttgttctgattcttcggacac cctgaggtttacattctaatccttcctgggttcggaatgatctctcacattgttacttat tattcaggaaaaaaagaaccttttggctatataggaatagtctgagcgataatatccatt ggattcttaggatttatcgtgtgagctcatcatatgtttaccgtaggtatagacgttgac acacgagcttacttcacttcagctaccataattattgctatcccgacaggagtcaaagta tttagctgactagccactctgcacggagggaatattaaatgatctcccgctatgatgtga gccctgggctttattttcctgtttacagtaggaggccttacgggaattgtcctagctaat tcatctctagacatcgttctccatgacacgtactatgtggtagcccattttcactacgtg ctgtcaatgggagctgttttcgccatcataggaggatttgtccactgattcccactattc tcaggctacacacttaataacacatgagcaaaaattcactttataattatattcattggg gttaatatgacattctttcctcagcattttctaggcctgtcaggaatacctcggcgatat tccgactatccagatgcctatacaacatgaaacacagtatcttctataggctcatttatt tcactaacagcagttatgctaataattttcatgatttgggaggccttcgcatcaaaacga gaggtggcagtggtagaacttacctcaaccaacattgaatgactacacggatgccctcct ccatatcacacattcgaagaacctgcctacgttacactaaaataa

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