Vulcanimicrobium alpinum: WPS_18080
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Entry
WPS_18080 CDS
T09508
Symbol
bkdA
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
vab
Vulcanimicrobium alpinum
Pathway
vab00280
Valine, leucine and isoleucine degradation
vab00640
Propanoate metabolism
vab00785
Lipoic acid metabolism
vab01100
Metabolic pathways
vab01110
Biosynthesis of secondary metabolites
vab01210
2-Oxocarboxylic acid metabolism
Module
vab_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
WPS_18080 (bkdA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
WPS_18080 (bkdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
WPS_18080 (bkdA)
Enzymes [BR:
vab01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
WPS_18080 (bkdA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
BDE06532
UniProt:
A0AAN1XYE8
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Position
complement(1759285..1761270)
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AA seq
661 aa
AA seq
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MELAAEGHRTTRVAPENLYAGLYRIRRFEQRTADLFRAGEVKGTAHSSIGQEAIAVGFGA
ALDARDYVVGHHRSHGHVLAKGGEPKRMFAELLGRAAGSCGGLGGSMHIADLALGILGCN
GVVGAGLGLGCGAALAAQLRGEDRVTVVFFGDGAAGEGVTHEALTLAAVWSLPVLFVCEN
NQYALTTEWRQSRPVERIAARGAAYAIPAETIDGNDVEGVLAHAVAAIAAVRAGDGPRLV
EAVTYRHLEHSMRANLPETRDLNRHEREVAADPIARYERALLERGFEAMQLANVRAAIDA
EIDDAIAWARVQPEASADGLMRAAYAPHAGSYPDVPSDAGRRLSLVGGVREALAQEMERD
RAVVLIGEDVEMGGIFTASQGLRDRFGAARVRNTPIAELGFADLAVGAAMTGLRPVVEIQ
IFDFVTLAMDAIVNQAAKLRFMMGGTATVPIVFRGPSGGGVRLAAQHSQSLEAWFAHVPG
LVVVAPSNARDAKGLLAAAIRDDNPVVFLEAKSILFDEGPVPEGETVIPLGVAEIKRAGS
DVSVVATQAMVRHALRAAQELAREGISVEVVDPRTLYPLDIKTILASARKTGRVVVAHEA
PVFAGIGAEIAAAVNEEAFFDLDAPVARVGAAHHPVPYADHLERSTLPTWERIVEAIRGL
P
NT seq
1986 nt
NT seq
+upstream
nt +downstream
nt
gtggaactcgctgcagaaggtcaccggacgactcgcgtagcgccggagaacctgtacgcc
gggctctaccggatacgccggttcgaacagcgcaccgcggacttgttccgcgcgggggag
gtgaaggggaccgcgcattcgtcgatcggtcaagaggcgatcgcggtcggtttcggagcg
gcgctcgatgcgcgtgattacgtcgtcggccaccaccgcagtcacggtcacgtcctcgcg
aagggcggtgaaccgaagcgtatgttcgccgagctgctcggacgtgcggccggatcgtgc
ggcggactgggcggctcgatgcatattgccgatctcgcgctcggcattctcggttgcaac
ggcgtcgtgggggcgggactcggcctgggctgcggcgctgcgctggccgcgcagcttcgc
ggcgaggatcgcgtcacggtcgtcttcttcggagacggtgcggcgggcgagggagtgacg
cacgaagcgctgacgcttgccgcggtatggtcgttgccggtgctcttcgtctgcgaaaac
aatcagtacgcgctcacgaccgagtggcggcagtcccggccggtggaacgcatcgcggca
cgcggcgccgcctacgcgatccctgccgagacgatcgacggcaacgacgtggagggcgtg
ctggcccacgccgtcgcggcgatcgcggcggtgcgggccggcgacggcccgcgactcgtc
gaagccgtgacctaccggcacctcgaacattcgatgcgcgccaacctgccggagacgcga
gatctcaaccgtcacgagcgcgaagtcgcggccgatcccatcgcacgctacgagcgcgcc
ctgctcgaacgcggcttcgaggccatgcagctcgcgaacgtgcgcgccgcgatcgacgcc
gagatcgacgacgcgatcgcgtgggcgcgcgtgcagccggaggcgtcggcggacgggttg
atgcgcgccgcctatgcaccgcacgccggcagctatcccgacgtgccgagcgacgccggc
cgccggctctcgctggtcggcggggtgcgcgaagcgctcgctcaggagatggaacgcgat
cgggccgtcgtgctgatcggcgaagatgtcgagatgggcgggatcttcacggcatcgcag
ggactgcgcgatcgcttcggtgccgcacgcgtgcgcaatacgcccatcgccgaacttggc
ttcgccgatctcgccgtcggtgcggcgatgaccggacttcgtccggtcgtcgagatccaa
atctttgatttcgtgaccctggcgatggacgcgatcgtcaatcaagccgcgaagctgcgg
ttcatgatgggcggcaccgcaaccgtcccgatcgtatttcggggaccgtcgggcggcggc
gtccggctcgccgcgcagcattcgcagtcgctcgaagcgtggttcgcgcatgtgcccgga
ctcgtcgtcgtcgcgccgtcgaacgcgcgcgatgcgaaaggcttgctggcggccgcgatc
cgcgacgacaacccggtcgtgttcttggaggcgaagtcgattctgttcgatgagggaccg
gtccccgaaggcgagacggtgatcccgctgggcgtcgcggagatcaaacgtgccggaagc
gacgtcagcgtcgtcgccacccaagcgatggtgcgccatgcgctgcgggcggcgcaagag
ctcgcgcgtgagggcatctccgtcgaagtcgtcgatccgcgcacgctgtatccgctcgat
atcaagacgatcctcgcatcggcgcgcaagaccggacgggtcgtcgtcgcgcacgaggca
ccggtcttcgccgggatcggcgcagagatcgccgcagcggtgaacgaagaggcgttcttc
gacctcgacgcgcccgtcgcgcgggtcggagcagcccatcaccccgttccttacgccgac
cacctcgaacggtcgacgctgccgacatgggagcgcatcgtcgaggcgatacgagggctc
ccatga
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