Nibricoccus aquaticus HZ-65: CMV30_12380
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Entry
CMV30_12380 CDS
T05426
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
vbh
Nibricoccus aquaticus HZ-65
Pathway
vbh00300
Lysine biosynthesis
vbh00550
Peptidoglycan biosynthesis
vbh01100
Metabolic pathways
vbh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
vbh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CMV30_12380
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CMV30_12380
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CMV30_12380
Enzymes [BR:
vbh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CMV30_12380
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ATC64689
UniProt:
A0A290Q7R1
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All DBs
Position
3097824..3099386
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AA seq
520 aa
AA seq
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MPSFAPAYLATWTGGQWTSKPALPLAGFTQDTRQLRAGQVFVALRTDKRDGHDFLATAMA
AGASAALVSRPDSSLALPQLVVADPLRAFQVIAREHRRAFRGAVVGVTGSCGKTSTKNLL
ARLLGGEPLVLATEGNLNNHLGVPLTLTRLEQGGHESAVIEAGISAPGEMDVLAGMIEPD
YGIVTLVAPAHTEELGGLPGVAREKAVLLQHVRPGGLSVFPKQCWDFHAFQDLPQQCIVL
VPEGESSNAPRTVKLGVRVSPTSTEITLGGRRRFDFRRVSRGMAENAGLAIILASELGVT
DDSIQRALDDWQPAKWRGEFRHDGQRLLYLDFYNANPASMIDALDSFASIVPADEPRLYV
LGCMEELGIESASYHRELGNRLRLRPQDRAFVIGGHAVDVVAGVADSGFSTENIEIVHTL
APVAAQIAAFRGAIFMKGSRRYELEKALPSESGDSHGSGHGSTSSGGSSAGGSSGSGGAG
PSAGTRSAFSMVSTAMPLSWQFPRATAARVSVRPGAFPFI
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcattcgcacccgcctatctcgccacctggactggaggtcagtggacctcgaag
cctgcgctgccgcttgccggtttcacgcaggacacgcggcagctccgcgcgggccaggtg
ttcgtggcgctgcgcaccgacaagcgtgacgggcatgattttctagccactgcgatggcg
gccggtgcgagtgcggcgctcgtgagccggcccgactcctcgctcgcattgcctcagctg
gtggtggccgatccgctgcgcgcctttcaagtgatcgcgcgcgaacaccgccgcgcgttt
cgcggagcggtggttggtgtcacgggtagttgtggaaaaacctccaccaaaaatcttctc
gcgcgtttgctcggcggcgaaccgctcgttctcgcgacggagggaaatcttaataaccac
ctcggcgtgccgctcacgctcacgcgactggagcagggcggccatgaatccgccgtgatc
gaagcgggaatcagcgcgccaggcgaaatggatgtgctcgcgggcatgatcgaaccggac
tacggcatcgtgacgctcgtcgcacctgcgcatacagaagagctcggcggcctgcccgga
gtggctcgcgaaaaagcggtgctccttcaacacgtgcggccaggcggcttgagcgtgttt
cccaaacagtgctgggacttccacgcgtttcaggatttgccgcagcagtgcatcgtactc
gtgcccgagggcgaatcgtccaacgcgccacgcaccgtgaagctgggcgtccgcgtgtcg
cccaccagcacggaaatcactctcggcggacgccgtcgtttcgactttcgccgggtcagc
cgtggcatggcggaaaatgccggcctcgcgatcattctcgcctcggaactcggggtcacc
gacgactcgatccagcgtgctctggatgactggcagcctgcaaaatggcgcggcgaattt
cgccacgatggccagcggttgctgtatctggatttctacaacgccaatcccgcatcgatg
atcgatgcgctcgattccttcgcgtccatcgtccccgccgacgagccgcgtctctacgtg
ctcggctgcatggaggagctcggcatcgagtcggcgagttatcatcgcgagctgggcaac
cgtctccgtctgcgtccgcaggatcgcgcgttcgtcatcggcgggcacgcggtggatgtg
gtcgcgggcgtggccgactcgggcttttccacagaaaacatcgagatcgtacacacgctc
gctccagttgccgctcagatcgcggcatttcgcggcgctattttcatgaagggcagccgt
cgctacgaactcgagaaggcgcttccctccgagtcgggtgactcgcacggctccggccat
ggcagcacgtcaagtggcggctcttccgctggtggttcgagcggctctggcggcgcgggt
ccgtcggcgggcacgcgctccgcgttcagcatggtttccaccgccatgccgctcagctgg
caatttccccgcgccacagcggcgcgtgtatcggtacgccccggcgcgtttccgtttatc
tga
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