Vibrio campbellii ATCC BAA-1116: M892_08210
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Entry
M892_08210 CDS
T02837
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vca
Vibrio campbellii ATCC BAA-1116
Pathway
vca00260
Glycine, serine and threonine metabolism
vca00261
Monobactam biosynthesis
vca00270
Cysteine and methionine metabolism
vca00300
Lysine biosynthesis
vca01100
Metabolic pathways
vca01110
Biosynthesis of secondary metabolites
vca01120
Microbial metabolism in diverse environments
vca01230
Biosynthesis of amino acids
Module
vca_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vca_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vca_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vca00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
M892_08210 (thrA)
00270 Cysteine and methionine metabolism
M892_08210 (thrA)
00300 Lysine biosynthesis
M892_08210 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
M892_08210 (thrA)
Enzymes [BR:
vca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
M892_08210 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
M892_08210 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Alba
Motif
Other DBs
NCBI-ProteinID:
AGU94611
LinkDB
All DBs
Position
I:complement(1782815..1785274)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADADRFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIEGALRNGEA
ELQINELEASFKALFADIQAVLPNIDGAAFDNQVKTSLSQLRQFVHGINLLGMCPNNVNA
RIISKGERVSIQLMKAVLEAKGQPAHLIDPVEYLYAKGDHLEAMVDVEVSTQKFRQNPLP
QGHVNIMPGFTAGNEKCELVTLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
EDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLNDLTMVNVSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIEAQDKAKAQQVLADAFELELKDGLLEPVEFIDDVSIVTLVGDGMRTSRGVASRFFSSL
AEVNVNIVAIAQGSSERAISAVIPEDKISEAIKACHENLFNSKHFLDVFVVGIGGVGGEL
VDQIERQQAKLAEKGIVIRVCGLANSKGLLLDSEGLPLEHWRDRMSAATEEFSLARLISL
VQRNHIINPVLVDCTSSEDIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRDVARSSR
RKLMYETTVGAGLPVIENLQNLISAGDELERFSGILSGSLSYIFGKLDEGMSLSEATNIA
KQNGFTEPDPRDDLSGMDVARKLLILAREAGMSLELEDVVVDQALPPGFDDSGSVEEFME
RLPEADAYFKELSAKAAEEGKVLRYVGEIVDGKCTVSIAAVDENDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattaaagtttggcggctcatcattagcagatgcagatcgctttttgagagcg
gcggatatcatcgccaacaacgcacaacaagaagaagtcgcagtggtactttctgcacct
ggcaaaacaaccaacaagctggtagcggtgattgaaggtgcgcttcgcaatggtgaagct
gaactgcaaattaatgagctggaagcttctttcaaagctctgtttgcagatatccaagct
gtattaccaaacatcgatggtgcagctttcgataaccaagttaaaacctcactttctcaa
cttcgccagttcgttcatggcatcaatcttcttggcatgtgcccaaacaacgtcaatgca
cgcatcattagtaaaggcgagcgcgtttcgattcagctgatgaaagcggtattggaagcg
aaagggcaaccagcgcatcttatcgacccagttgaatacctctacgcaaaaggcgatcac
ctagaagccatggtcgatgttgaagtttcaactcagaagttccgtcagaaccctcttcct
caaggccatgtgaatattatgccgggctttaccgcaggtaacgagaaatgtgaactagtt
acactaggtcgtaatggttcagactactcagcagcggttcttgcggcttgtctgcgcgca
gattgctgtgaaatctggacagacgttgatggcgtgtacaactgtgaccctcgcttagta
gaagatgctcgtctgcttaaatcgcttagctaccaagaagcgatggagctttcttacttc
ggtgcttctgttctgcacccgaaaaccatcgcaccaatcgcacaattccatattccttgt
ctgatcaaaaacagctttaacccacaaggtgcgggtacgctgattggtcaagacactggc
gaagataacctcgctatcaaaggcatcacgacgctgaacgacctaacgatggttaacgtg
tctggcccgggtatgaagggtatggttggcatggcaagtcgagtatttggcgcaatgtca
tcagcaggtgtgtctatcgttctgatcactcaatcttcttctgagtacagcatcagcttc
tgtatcgaagcgcaagacaaagcaaaagcacaacaagtattggcggatgcgtttgaactt
gaattaaaagacggtctactcgagcccgttgagtttattgatgatgtgtctatcgtcact
ttggttggtgatggtatgcgtacttcacgcggtgttgcatctcgcttcttctcatctctt
gctgaagtgaacgtaaacattgtagctatcgcacagggctcatctgagcgtgctatctct
gccgtgattcctgaagacaaaatctctgaagcgatcaaagcgtgtcacgagaacctattc
aactctaagcacttcctagacgtattcgtggttggtattggcggcgttggtggtgagctg
gtggaccaaatcgagcgtcaacaagcgaagcttgcggaaaaaggcattgtgattcgcgta
tgtggcttggcaaacagcaaaggtcttctgcttgatagcgaaggtctgccactagagcat
tggcgtgaccgtatgtcggcagcgacagaagagttcagcctagcgcgtttgatttctttg
gttcaacgtaaccacatcatcaacccagtattggtggactgtacttcaagtgaagatatc
gcgaatcaatacgctgatttcttagcggctggtttccacgtagttacaccaaacaagaaa
gcaaacacagccagcatgtcttactaccatcagcttcgcgatgttgcgcgcagctctcgc
cgtaagctgatgtacgaaacaaccgtaggcgcaggtctaccggtgatcgaaaacctacaa
aacctaatctcagcgggtgatgaactagagcgcttcagcggtatcctttctggctctctg
tcatacatcttcggtaagttagatgaaggtatgagcctaagtgaagcaaccaacatcgcc
aagcaaaatggctttactgaaccggatcctcgtgacgatctatcgggtatggatgtggcg
cgtaagctacttatccttgctcgtgaagctggcatgtctctagaactagaagacgttgtg
gttgatcaagctctgccaccaggttttgacgactcaggcagtgttgaagagtttatggag
cgcttaccagaagcggacgcctactttaaagagctgtcagctaaagcggcagaagaaggc
aaagtactgcgctacgtgggtgaaattgttgatggtaaatgcacagtaagcattgcagca
gtcgatgaaaacgaccctatgtttaagatcaaagatggtgaaaacgcactggcattctac
agccgctactaccaaccaattccactggtattgcgtggttacggtgcgggtactgaggtt
acggctgctggcgtattctcggatgtgatgcgtactttaggttggaagctaggggtataa
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