Vibrio campbellii ATCC BAA-1116: M892_08785
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Entry
M892_08785 CDS
T02837
Name
(GenBank) 2-isopropylmalate synthase LeuA
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
vca
Vibrio campbellii ATCC BAA-1116
Pathway
vca00290
Valine, leucine and isoleucine biosynthesis
vca00620
Pyruvate metabolism
vca01100
Metabolic pathways
vca01110
Biosynthesis of secondary metabolites
vca01210
2-Oxocarboxylic acid metabolism
vca01230
Biosynthesis of amino acids
Module
vca_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
vca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M892_08785
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M892_08785
Enzymes [BR:
vca01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M892_08785
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
AGU96564
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Position
I:1926195..1927742
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AA seq
515 aa
AA seq
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MNDQVIILDTTLRDGEQALSASLTVKEKLQIAYALERLGVDVIEAGFPVSSPGDFESVQT
IAKHIKNSRVCALSRAVAKDIDAAAEALKVADAFRIHTFISTSTVHVQDKLRRSYDDVVE
MGVKAVKHARNYTDDVEFSCEDAGRTPIDNLCRMVEAAIDAGASTINIPDTVGYTVPSEF
GGIIETLFNRVPNIDKAIISVHCHDDLGMSVANSIAAVQAGARQVEGTINGIGERAGNCS
LEEIAMILKTRQEFMGVHTGLKHDEIHRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIH
QDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDAMGYKEEEYNLDALYEDF
LKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSVKMQCGDEEMCE
AAVGNGPVDALYQCIYRVTGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVS
TDIVEASGQALLHVINSIHRADKIEEMKQKRIATV
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgaacgatcaggtcattatactcgacaccacattgcgtgatggcgaacaagcgttgtca
gcaagcttgacggttaaagaaaaactgcagattgcctatgcgctggaaaggctaggcgtt
gatgttatcgaagcgggttttcctgtttcttctccgggtgatttcgagtccgtacaaacc
atcgcaaaacacattaaaaacagccgagtttgtgccctttcgcgtgccgttgcgaaagac
atcgatgctgccgctgaagcgctaaaagtcgcggacgcattccgaatccacactttcatc
tcgacctcgactgttcatgttcaagacaagctgcgccgtagctacgacgatgttgtagaa
atgggcgtgaaagccgtaaaacacgcacgtaactacaccgatgacgttgagttttcttgt
gaagatgctggtcgcacccctatcgacaacctatgtcgtatggttgaagcggctatcgat
gctggcgcaagcaccatcaatatcccagataccgttggctacacagtaccaagtgaattt
ggcggcatcattgagaccctattcaaccgcgtaccgaacatcgacaaagcgatcatctct
gttcactgtcacgatgacttgggtatgtctgttgccaactctatcgcagccgtgcaagcg
ggtgctcgtcaggtagaagggactatcaacggcatcggtgagcgtgcgggtaactgttct
ctcgaagaaatcgcgatgatcctaaaaacgcgccaagagttcatgggtgtgcataccggt
ctaaaacacgacgaaatccaccgtaccagcaagttggtcagccagctttgtaacatgcca
atccagagcaacaaagctatcgttggtgctaacgcgttcagccactcttcaggcattcac
caagatggcatgctaaagaacaaaaacacttacgagatcatgacgcctgagtcgattggt
cttaagaaccaagcattgaacctaaccagtcgcagtggccgtgctgcggtgaagagccac
atggacgcgatgggctacaaggaagaagagtacaacctagatgcgctgtacgaagacttc
ttgaagcttgctgaccgcaaaggtcaggtgttcgactacgatctagaagcgctaatgcac
ttctctaacttgcgcgaagaagacgacttctacaagttgaactacctaagcgtgcaatct
ggcagcgtaatggcaaccaccagcgtcaaaatgcaatgtggcgatgaagaaatgtgtgaa
gctgccgtcggtaatggtccagttgatgcgctataccaatgtatctaccgcgtaacaggt
tacgagatcgtcctagacaagtttgacctaacagcaaaaggtgaaggtgaagacggcctg
ggccaagcagatatcatcgccaactacaaaggtcgtaagtaccacggtaccggcgtttcc
accgacattgtagaagcttctggtcaagcgctattgcacgtcatcaacagcattcatcgc
gccgataagattgaagagatgaagcaaaagagaattgcgacggtttaa
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