Vibrio cholerae O1 El Tor FJ147: IR04_12495 Help Entry IR04_12495        CDS       T03827                                  Name (GenBank) peptidase C80   KO K10953   RTX toxin RtxA Organism vcf  Vibrio cholerae O1 El Tor FJ147 Module vcf_M00850   Vibrio cholerae pathogenicity signature, cholera toxins Brite KEGG Orthology (KO) [BR:vcf00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:vcf02042]     IR04_12495 Bacterial toxins [BR:vcf02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    IR04_12495 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACD RtxA Peptidase_C80 MLD RtxA_C Abhydrolase_1 Hydrolase_4 Abhydrolase_6 Abhydrolase_3 DUF1057 Thioesterase DUF4105 Abhydrolase_11 Motif Other DBs NCBI-ProteinID:  AJZ99939 LinkDB All DBs Position I:1633434..1647035 Genome browser AA seq 4533 aa AA seqDB search MGKPFWRSVEYFFTGNYSADDGNNNIVAIGFGGQIHAYGGDDHVTVGSIGATVYTGSGND TVVGGSAYLKVEDSTGHLIVKGAAGYADINKSGDGNVSFAGAAGGVSIDHLGNHGDVSYG GAAAYNGITRKGLSGNVTFAGAGGYNALWHETNQGNLSFTGAGAGNKLDRTWSNRYQGSH GDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGDITLQGAGASNRIERTHQA EDVYTQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNTIIRKGSGNDFAKEGMTNAK ADEIVLTKAVMSGSWIGQDHHVTAVKSASEPNTYLFAFADSTYTKINKVQLRNDPQTGEL KYYSTAWYKEVNHLSNLANQDISDNGGFTAVNINGAYTLSDLKVEHQQSVTVHAVEKSLT EYEWVTYANGAVIDAKEVSLSDAKMGGHAIYADGTKVDVKAVKSNRQPNTYIYAKVLGPY TKIVVVELANDPETGALKYQARSWYKEGDHTANIANQDISSATGYNPMGKGGYSLSDLHY SVNAVRSTSETVADIEEYTDQTLFKPANDSGESSGDVRFNGAGGGNVIKSNVTRGNVHFN GGGIANVILHSSQFGNTEFNGGGAANVIVKSGEEGDLTFRGAGLANVLVHQSEQGKMDVY AGGAVNVLVRLGDGQYLAHLLAYGNISVQKGSGDSRVVMLGGYNTHTQIGSGNGLWLAAG GFNVMTQVGKGDVAAVLAGGANVLTKMGEGELTSGMLGGANVITHISNDDQLSNTTAVAL GGANILTKKGKGNTLAVMGGGANVLTHVGDGTTTGVMVGGANILTKVGNGDTTGILLGVG NVLTHVGDGQTLGVMGAAGNIFTKVGDGTSIAVMIGAGNIFTHVGEGNAWALMGGLGNVF TKVGNGDALALMVAEANVFTHIGDGMSVALMLAKGNVATKVGNGTTLAAMVGNVNIFTHI GHGSTFAAMIGQANIMTKVGNDLTAALMVGKANIMTHVGDGTSLGLFAGEVNVMTKVGNG TTLAAMFGKANIMTHVGDGLTGVLALGEANIVTKLGDDFMGVVAAAKANVVTHVGDATTA AVLAGKGNILTKVGEGTTVGLLISDVGNVMTHVGDGTTIGIAKGKANLITKVGDGLGVNV TWGQANVFTQVGDGDRYNFAKGEANLITKVGDGQEVSVVQGEANIITHVGNGDDYTGAWG KANVITKVGHGQNVVLAKGEANIVTQVGDGDSFNALWSKGNIVTKVGDGMQVTAAKGQAN ITTTVGNGLNVTAAYGDANINTKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANI HVGDGLNINASYAQNNVAIKVGNGDFYSLAVASSNTSSNKLSALFDNIKQTVLGVGGSQA INYLVQGDEASSSGTHKGRGAIATPEITKLDGFQMDAIKEVSSDLGDSLTGSVTKVDTPD LNKMQHALNVDDSSVQAPNLIVNGDFELGEHGWQSTHGVEASYAGSVYGVEGEGHGARVT ELDTYTNTSLYQDLANLAQGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDESAW QQKNLKLTAQAGSNRIEFKGTGHNDGLGYILDNVVATSESSQQANAIREHATQNPAAQNA LSDKERAEADRQRLEQEKQKQLDAVAGSQSQLESTDQQALENNGQAQRDAVKEESEAVTA ELAKLAQGLDVLDGQATHTGESGDQWRNDFAGGLLDGVQSQLDDAKQLANDKIAAAKQTL SDNNSKVKESVAKSEAGVAQGEQNRAGVEQDIADAQADAEKRKADALAKGKDAQQAESDA HHAVNNAQSRGDRDVQLAENKANQAQADAQGAKQNEGDRPDRQGVTGSGLSGNAHSVEGA GETDSHVNTDSQTNADGRFSEGLTEQEQEALEGATNAVNRLQINAGIRAKNSVSSMTSMF SETNSKSIVVPTKVSPEPERQEVTRRDVRISGVNLESLSAVQGSQPTGQLASKSVPGFKS HFASTSIGIENELSGLVVVLPKNSAQTFGYVHDSQGNPLFMLTKDMNQGGYSNPVGINDI QGVNNWQTHTIELVTYPSEISDTAAVESRKEAMLWLAKEFTDHINQSNHQSLPHLVSDDG RFTLVISNSKHLIAAGNGTSIDAQGKTIGMTPSGQQATMAISAKEFGTSSSPEVRLLESA PWYQAGLRDEFLANAKNTTLDDPATAQNVYAYLTSVYSKTADLAKEYGIYINDWDPASEG FSPNAQGLTDPKVKNAWSILPRTKPVRMLELLSAEDSRYVRQQIAEKLKGTYSESLAKNV FEYFQYGGEVAGHGINNATTGSVQQPEPAILFEFRSVPSALSDFVPKTASTVKVDVKALD HFDSASRKAIITEVNALVSGSEDFDAWYQEYRASKGQPPVKNPKSSASANHKAEWLMTQH AEQWAKITAPYTDNHETLTSTKLASNDKEELHALGETSNLENNKQQENVASIINTMLNDM LPFYALRTERNLLVQEGDEGFEVRAWPGTEDKSKTIILEDPEDAAQHKAIERFILANFDN FEQMPDELFLVDNKVISHHEGRTHVLAQKVDGAWQYNATVELMSVTELLDAANVTGKIRG ESYQQVIDALTDYHASITEHADYEPESVEKLLNLRKKIEGYVLGHPDSGRVEAMNSLLNQ VNTRLDEVSLLSVAEQTIQAQNSFSRLYDQLEAANLKESKHLYLDQNGDFVTKGKGNLAN IDLLGSREAVLEKVKLTVSNEYGQTVADTIFAGLSAKDLAKDGKGVDIAGLNKVHQAIEQ HLSPVSATLYIWKPSDHSALGHAALQIGQGRTQLEGQAAADFNQQNYVSWWPLGSKSSNI SNILNVATKDQPDLKLRWSDFSQPAHQNDTLEHDVASEENDGFGLHDGDIKLKRFIEKLN AAKGIDASFKEASEGYASVLLGNPDMLETTSIPAHVFQPFVEQWNDTSYDMMDVAHRFAQ ELRLQAQRSDDPELLEKRIGNVIRQFAERALEEIETFKASQADQGRVFRINLEGLDVAAM QAEWHRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWLPKFGVWTPTELFNFGQ ALQEAQLEIAAKKQSHQVTDVLDALSGNEKPKENVAIENDGTPPRDKESLSPLTRFLNNE LYGDKEARRKIGEITQTLLDHAVEKGESQKITLQGEAGRLTGYYHQGTAPSEGETSSPSG KVVLFLHGSGSSAEEQASAIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTMFN YLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITAHEV ANPAGIVGAIAKAVNGQFSVEKNLEGLPKETSILLLTDNEGLGNEGEKLRTKLTASGYNV TGEQTFYGHEASNRLMSQYADQIVSGLSSSASVDEDLDQQGLDTTSTKDQGISNKNDHLQ VVDSKEALADGKILHNQNVNSWGPITVTPTTDGGETRFDGQIIVQMENDPVVAKAAANLA GKHAESSVVVQLDSDGNYRVVYGDPSKLDGKLRWQLVGHGRDHSETNNTRLSGYSADELA VKLAKFQQSFNQAENINNKPDHISIVGCSLVSDDKQKGFGHQFINAMDANGLRVDVSVRS SELAVDEAGRKHTKDANGDWVQKAENNKVSLSWDAQGEVVAKDERIRNGIAEGDIDLSRI GVNNVDEPARGAIGDNNDVFDAPEKRKPETEVIANSSSSNQFSYSGNIQVNVGEGEFTAV NWGTSNVGIKVGTGGFKSLAFGDNNVMVHIGDGESKHSVDIGGYQALEGAQMFLGNRNVS FNFGHSNDLILMMDKSIPTPPLVNPFDGAARISGVLQGIATSGEGEDWLAAQEQQWTLSG AKKFVKDMSGLDQSSSVDYTTLVELDSQNERDSRGLKHDAEATLNKQYNQWLSGNGNSGT SQLSRADKLRQANEKLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMT QQFTATGQAKTTFTYTPQDLPRQLKNKLLGQLAGVGAETTLADIFGVDYTASGQIVSRNG QAVDGVAILKEMLEVIGEFSGDQLQAFVDPAKLLDSLKAGIDMGADGIKSFAETHGLKEK APEEEKDNSSVSVNGANVNSAQGATVADGNTETAETQDRAFGFNSLNLPNLFATIFSQDK QKEMKSLVENLKQNLTADLLNMKEKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDL GAYLGDNNNFWGGRGDDVFYATGKSNIFTGGEGNDMGVLMGRENMMFGGDGNDTAVVAGR INHVFLGAGDDQSFVFGEGGEIDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVEL GAGNDFANIFGNYNRINAGAGNDVVKLMGYHAVLNGGDGDDHLIATAISKFSQFNGGEGR DLMVLGGYQNTFKGGTDVDSFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDL KLSILRDPSNDSDQSKFEHIGSVTFSDYFNGNRAQVVIGMSEKDLSGEREYTMLSDSAID ALVQAMSGFEPQAGDNGFIDSLESKSQAAISMA NT seq 13602 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaccattttggagaagtgttgaatacttcttcacaggaaactattccgccgac gatggaaacaacaacattgtagccattggttttgggggacaaattcatgcctacggcggt gacgaccacgtcactgttggatcgattggtgcaacggtgtacaccggtagcggcaacgat acggtcgtgggcggctctgcctatctcaaagtggaagattccactggccacctaattgta aaaggcgcggctgggtatgcagacattaataaaagtggcgatggcaatgtgtcattcgct ggtgccgccggtggtgtgtcgattgaccacttaggcaatcatggtgatgtcagttacggc ggtgccgcggcttataatggcattacccgtaaagggttgagcggcaatgtcacctttgca ggcgcggggggatacaatgccctctggcatgaaaccaaccaagggaacctgtcttttaca ggagcaggcgcaggtaataaattagaccgtacttggtctaaccgttatcaaggctcgcat ggcgatgtgacctttgatggtgctggtgccgcgaacagcatcagttcacgcgttgagaca ggtaacatcaccttccgtggcgcaggtgcggataaccatttagtccgtaaaggcaaagtg ggcgatattactctgcaaggtgctggggcttcaaaccgcattgagcggacacatcaggcc gaagatgtctacacgcaaacccgcggcaatattcgttttgaaggtgtgggtggttacaac agtctttactctgatgtggctcatggtgacattcatttctcgggtggcggtgcgtacaac accattattcgtaaaggttctggaaatgactttgcgaaagaaggcatgaccaatgctaag gctgatgagattgtattaactaaggccgtgatgagtggctcatggatagggcaagatcat catgtcacagcggtgaaatcggctagcgagcctaatacatatctttttgctttcgcagac tctacgtataccaaaattaacaaagtacagttacgcaatgatcctcaaactggagaactg aaatattactctacggcttggtataaagaggttaaccatctaagcaacttagcgaatcaa gacatttccgacaacggtggtttcacagccgttaatatcaatggcgcctacacgctatct gacctcaaagttgaacatcagcaatccgtcaccgttcatgcggttgaaaaaagcctgact gaatatgagtgggtgacttacgccaatggtgcggtgattgatgcgaaagaggtgtcattg tcggatgccaaaatgggcggtcatgcgatttatgctgatggcactaaggtggatgtcaaa gcggtaaaatccaaccgccaacccaacacttacatttatgccaaagtgcttgggccttac acaaaaattgtggtggtggaactggcaaacgatcccgaaaccggggcactgaaatatcaa gctcgctcttggtataaagaaggtgatcacacggccaatatagccaaccaagatatttca tctgcaactgggtataacccaatgggcaaaggtggctactcgctcagtgacttgcactac agcgtaaacgccgttagaagtaccagcgaaaccgtagcggatatcgaagaatacacagat caaaccttgtttaaacccgcaaacgatagcggtgaaagctcaggtgatgttcgtttcaac ggtgccggtggcggtaacgtcatcaaatcaaacgtgacgcgtggtaatgtgcatttcaac ggtggcggtattgccaacgtgattttgcatagctcccaatttggtaataccgaatttaac ggtggtggtgcggcgaacgtcattgtcaaaagtggcgaagaaggggatctcaccttccgc ggcgcaggtttggcgaacgtcttggtacaccaaagcgaacaaggcaagatggatgtgtac gcgggcggtgcggtaaacgtgttggttcgccttggcgatgggcaatatctcgcgcattta ctggcttacggtaacatttcagtccaaaaaggcagtggtgatagtcgcgtcgtgatgctc ggtggctacaacacccatacccaaatcggctctggcaacggattatggttggccgcgggc ggtttcaacgtgatgacgcaagtcggcaaaggtgatgttgctgcggtactcgctggcggt gcaaacgtactgaccaaaatgggtgagggtgaactcacgtcgggtatgctgggtggcgcg aacgtaataacccacatcagcaatgatgatcaattatcgaataccacggctgtggcactt ggcggtgcaaatattctcaccaaaaaaggcaaagggaatacccttgcggtgatgggtggt ggcgcaaacgtgcttacccatgttggtgatggcaccacaacgggtgtcatggtcggcggt gcgaacattctcaccaaagtaggtaacggcgacacgaccggcattctgcttggcgttggc aacgtgctgacgcatgtgggtgatggccaaacccttggcgtaatgggcgcggcgggtaac atcttcaccaaagtgggtgatggaacctctattgcggtcatgattggtgctggcaacatt tttacccatgtgggggaagggaatgcttgggcgctgatgggcggcttgggtaacgtcttt accaaagtaggcaacggtgatgctctcgcgttaatggtagcagaagccaacgtcttcact cacattggtgatggcatgtcggtggcactgatgttagccaaaggcaacgttgcgacaaaa gtgggtaatggaaccacactcgcggcgatggtggggaacgtcaacatctttacccatatt ggtcatggcagcacgtttgcggcgatgatcggccaagccaatatcatgaccaaagtgggc aatgatctcacggcggcgctgatggtcggcaaagcgaacatcatgacccatgttggcgat ggtaccagcctagggctgtttgctggcgaagtgaacgtgatgactaaggttggtaacggc accacgttagcggcgatgttcggtaaagcgaacatcatgacccatgtcggtgatggctta accggtgtactcgcactgggtgaagccaatatcgtgaccaaattgggtgatgatttcatg ggggtggtggccgcggctaaagccaacgtcgtgactcatgttggtgatgctaccaccgca gccgtattggcgggtaaaggcaatatcctcaccaaggtgggtgaaggcaccacggtaggg ttgttgatttccgatgtcggcaacgtgatgacccacgttggtgacggcaccaccattggt attgccaaaggtaaggccaacctcattaccaaagtcggtgatggtttaggtgttaatgtc acttgggggcaagccaacgtgtttacccaagtgggcgacggtgatcgctataactttgcc aaaggtgaagccaacctcatcaccaaagtgggtgatggccaagaagtctccgtggtgcaa ggtgaagccaacatcattactcatgtgggcaatggcgacgactacactggcgcttggggt aaagcgaacgtcattactaaagtcggtcatggccaaaacgtggtactggcaaaaggtgaa gccaacattgttactcaagtgggtgatggcgacagctttaacgcactttggagcaaaggc aacatagttaccaaagtgggcgatggtatgcaggtgacggcggcaaaaggccaagccaat atcaccaccaccgtgggtaacggtttaaatgtcactgctgcctacggcgatgccaatatc aacaccaaggtcggtgatggggtatccgtcaacgtcgcttggggcaaatataacatcaac acgaaagtgggtgatgggctcaatgtcgctgtgatgaagggcaaagctaacgccaatatt cacgttggggacggcctcaacatcaatgcctcctacgcacaaaacaacgtcgccatcaaa gtcggtaacggcgatttctatagtttagcggtggcatcgagcaataccagcagcaacaag ctctctgccttgtttgataacatcaaacaaaccgtactcggtgtcggtggcagccaagcc atcaactacttagtgcaaggcgatgaagcctcctcatccggcacgcataaaggtcgtggt gcgattgctacacctgaaatcaccaaactggatggtttccaaatggatgccattaaggaa gtcagttctgacctcggtgatagtctcacgggcagcgtgactaaggttgatactcctgat ctcaacaagatgcagcatgcgctcaatgttgatgattcttccgttcaagctccgaatctg attgtgaatggggattttgagctgggcgaacatggctggcaatctactcatggggttgaa gcctcttatgcaggcagtgtgtatggcgtagagggtgaaggtcacggcgcacgtgtgacc gagctcgatacttataccaacaccagtctctatcaagatctggctaatctagcgcaaggt gaagttattgcggtgagctttgattttgcaaaacgcgcgggcctttctaataacgaaggc atcgaagttctttggaacggtgaagtggtattctcatcgtcgggtgacgagtctgcttgg cagcaaaaaaacttaaagctgaccgcgcaggctggcagtaaccgtatcgaattcaaaggc acaggccacaatgatggactgggctacatcctagataatgtggtggcgacctcagagtca tcgcaacaagccaatgcaatccgtgagcacgcaacgcaaaacccagcagcgcagaatgct ctatccgataaagagcgtgcagaagcggatcgccaacgtcttgaacaagaaaagcagaaa cagcttgatgctgtcgcagggtcacaaagtcagttggagtcgaccgaccaacaagcgcta gaaaataatggtcaagctcaacgtgatgcggtgaaagaagagtcggaagccgtgaccgcc gagttggcaaaactggcgcaaggtctcgatgtgcttgatggccaagcaacgcatactggc gagtccggcgaccaatggcgcaatgattttgccggtggtctgctcgatggcgttcaaagc cagctcgacgatgccaagcaactcgcgaatgacaagattgctgcagcgaagcagaccctg tctgacaataacagcaaagtcaaagaatccgttgcgaaatctgaagcgggtgtggcacaa ggcgagcaaaatcgagcgggagtagagcaagacattgctgatgctcaagccgatgctgaa aaacgtaaagccgatgctttagcaaaaggtaaggatgcacaacaagcggaatctgatgca catcatgcggtaaataatgctcaatcacgcggcgatcgtgatgtgcaattggcggaaaac aaagccaaccaagcacaagccgatgctcaaggtgctaaacaaaacgaaggtgatcgtcct gatcgtcaaggcgtgactggtagtggcctttcgggtaatgctcatagtgtggaaggcgct ggcgaaacagacagtcatgtcaacaccgacagccaaaccaacgccgatggccgattcagt gaaggtttaaccgaacaagagcaagaagcgctagaaggtgcgaccaacgcagtgaaccgt ttgcaaattaacgcaggtattcgagcgaaaaacagcgttagcagtatgacttctatgttc tctgaaacaaatagcaagagcattgttgttcctaccaaagtctcgcctgaaccagagcgc caagaagtgactcgtagagacgtccgtatctcaggggtgaacctcgaaagtctaagtgcg gtacagggaagtcaaccaacgggtcaactggcttcgaaaagtgtccccggatttaaaagc catttcgcatcgacatccattggtatagaaaatgagttatccggtctggtggtggtttta ccgaaaaactcagcgcagacttttggctatgtgcatgattcacaaggtaacccattgttc atgctaaccaaggatatgaatcaaggtggttatagcaacccagtgggtatcaatgatatt caaggggtgaacaactggcagacgcatacgattgaactggttacatatcctagtgaaatc agtgatacagcagcggttgaaagtcgtaaagaggcaatgctatggcttgcgaaagagttt accgatcatatcaatcagtctaaccaccaaagcttacctcatttagtgagtgatgacggt cgtttcactctggttatatcgaactctaagcatcttattgcggcgggtaacggaacctct attgatgcacaaggcaagaccataggaatgacccctagtggccaacaagcaacaatggcg atcagtgcgaaagaatttggtacaagctcgtcgccggaagtcagactgcttgaatctgcg ccttggtatcaagcagggttgagagatgagtttttagcaaacgcgaaaaacaccacgttg gatgatcccgctacagcacaaaatgtgtatgcctatctcacgtctgtctattcaaaaaca gcagatttggccaaagagtatgggatctacatcaatgattgggatcctgcctctgaaggt ttttcaccgaatgctcaagggttaacggatccgaaagtcaaaaatgcttggagcatattg ccaagaactaaacccgttagaatgctggaacttctgagtgcggaagactcacgctacgta aggcaacaaattgcggaaaagctgaaaggcacctattcagaaagccttgctaagaacgtg tttgaatacttccaatatggtggagaagtcgctggacatggaatcaataatgcgacgaca ggaagtgtgcaacagcctgaaccagcgatcttatttgagtttcgcagtgtaccgagtgca ttaagtgactttgtacccaaaacagcgtcaacggtgaaagtggatgttaaggcactcgat cattttgactcggcaagccgtaaagccatcattactgaagtaaatgctttggttagcggt agtgaggatttcgatgcttggtatcaggagtatcgagcaagcaaaggacagccgccagtc aaaaatcctaagtccagtgcatccgccaatcacaaagctgaatggttgatgacgcagcat gctgaacaatgggcgaaaattaccgctccttatactgataaccatgagacgctcacatct accaagcttgcttctaacgataaagaagaattacacgctttaggtgaaacgtcgaatcta gagaataacaagcagcaagaaaacgtcgcttccataattaacaccatgttaaatgacatg ctgccattctatgcacttcgtaccgaacgaaatctactggtacaagaaggagatgaaggc ttcgaagtgcgtgcttggccaggaaccgaagacaagagtaaaaccattattcttgaggat cctgaagacgcggctcagcacaaagccatcgaacgcttcattctggccaacttcgataat ttcgaacaaatgccagacgagctcttcttggtggataacaaagtgatttcacaccatgaa ggtcgtacacatgtgttggcgcaaaaagtcgatggtgcatggcaatacaacgccacagtc gagctgatgtcagtcactgaactactggatgcggcgaatgtaacgggtaagatccgcggt gaaagctatcagcaagtgatcgacgcattgactgattaccacgccagcatcactgagcac gcagattatgaaccggagtccgtggaaaaactgctcaacttgcgtaaaaaaattgaaggt tatgtactcggacacccagactcaggccgtgttgaagcgatgaattcactgttaaatcag gtgaatacgcgtttagatgaagtttcactgctgtcagttgctgagcaaactatccaagcg caaaacagtttcagccgactatatgaccagctagaagccgctaacttgaaagagagtaag cacctttatctggatcaaaatggtgactttgttaccaaaggcaaaggtaatcttgccaat atcgatctgctaggtagccgcgaagctgtgcttgaaaaagtgaagttaacagtaagtaac gagtacggtcaaaccgttgcggatacaatttttgctggattatcagccaaagatcttgcc aaagacggtaaaggggttgatatcgcgggtttgaataaagtacatcaagcgattgaacag catctgtcacctgtcagcgccacgttgtacatttggaaaccgagtgatcatagcgcgcta ggtcatgccgcattgcaaataggccaaggtcgcacgcaacttgaaggtcaagctgcagct gattttaaccagcaaaattacgtaagctggtggccactaggcagcaagtcatccaatatc agcaatatcttgaatgtggccacaaaagaccaacctgatcttaagctgcgctggagcgac ttcagtcaacctgcacatcaaaatgacacgcttgagcatgatgttgcttcggaagaaaac gatggctttggtttgcatgatggcgacattaagctgaaacgctttatcgagaagctcaat gccgcgaaaggaattgacgcttcatttaaagaggcttctgaaggttacgcgagcgtacta ctgggtaacccagatatgctcgaaacgacaagtattcctgcacatgttttccaaccattt gtcgaacaatggaatgacaccagttatgacatgatggacgtggcacaccgttttgcgcaa gagctcagactacaggctcaaagaagtgacgatcccgaactgcttgaaaagcgcatcggc aatgtgattcgccaatttgcagaaagagcactggaagagatcgaaaccttcaaagcaagc caagccgatcaaggtcgagtattccgaattaaccttgaaggcctcgatgtggcggcaatg caagcagaatggcatcgtctaagcaacgatccggatgctcgttatcaattactgaccaaa aactgctccagcacagtggctaaagtgttgaaagccggcggggcggataaactgattggc catacatggctgcctaagtttggtgtttggacgccgaccgagcttttcaactttggtcag gcactgcaggaagctcagctggaaattgccgcgaagaagcaaagtcatcaagtcactgat gtccttgatgccttgtcaggcaatgagaagcctaaagaaaacgtggcgattgaaaatgat ggtacgccaccgcgcgataaagaatctctgagcccattgactcgattcctcaataacgag ttgtatggtgataaagaggctcgccgtaagattggcgaaatcacgcaaaccctacttgat cacgcggtggaaaaaggtgaatcgcagaaaatcactctgcaaggagaagcgggccgtcta acggggtattaccatcagggaacagccccaagcgaaggtgaaacgagctcgccaagcggc aaagtcgtattgttcctgcacggttctggttcttctgctgaagagcaagcgagcgcgatt cgaaatcactaccagaagcaaggtatcgatatgctcgcagtcaacctgcgtggctatggt gaaagcgacggtggaccaagcgaaaaaggcttgtaccaagatgctcgcaccatgttcaac tacctagtgaatgataagggtattgacccaagcaacatcatcattcacggctactcaatg ggcggtccaattgccgcagatttagcacgttatgccgcgcaaaacggccaagcggtgtct ggcttattgcttgaccgtcctatgccaagcatgaccaaagcaatcaccgctcacgaagtg gcgaatccagcgggcattgtgggggctatcgcgaaagcggttaacggccagttctctgta gagaaaaatctcgaaggtttgccaaaagagacatccattctgctgttgaccgataacgaa ggtttgggtaacgaaggtgagaaacttcgtaccaaactcactgcctctggttacaacgtc actggcgagcagacattctatggtcacgaagcaagcaaccgtttgatgagtcaatatgcg gatcaaattgtctccggtttgtccagcagtgcaagtgtagatgaagacctagatcaacaa gggttggataccacatcaaccaaggatcaaggtatctcaaataagaatgatcatctgcaa gtggtggatagtaaagaagcattagcggatggaaaaatactccataatcaaaatgttaat agctggggcccgattacggttacaccaacgacagatggtggtgaaacccgcttcgacggt caaatcatcgttcaaatggaaaacgacccggtagtagcaaaagcggcagccaatttagca ggtaaacatgctgaaagcagtgtggtggtgcagctcgattcagacggcaactatcgcgtg gtgtatggcgatccgtcaaaactggatggaaagctacgttggcagttggtggggcatggt cgcgaccactcagaaactaacaatactcgcttaagtggttacagtgccgatgagttggcc gtgaaattggccaagttccaacagtcgtttaatcaagccgaaaacatcaacaacaaaccg gatcacatcagtattgttggttgttctttggtgagtgacgacaagcaaaaaggctttggt catcagtttattaacgcgatggatgcgaatggtcttcgtgtcgatgtctctgttcgtagt tctgaactggccgtagacgaggcgggacgtaagcataccaaggacgcgaatggcgattgg gttcaaaaggcagaaaacaacaaagtttcgctaagctgggacgcgcaaggtgaagttgtt gccaaggatgaacgtattcgcaatggtattgcggaaggcgacatcgatctctctcgtatt ggtgtcaacaatgtcgatgaacctgctcgtggcgcgatcggtgacaataatgacgtgttt gatgcgccagaaaaacgcaaaccagaaacggaagtgattgccaattctagcagcagtaat caattcagctactcaggtaacattcaagttaacgtgggcgaaggggagtttacggcggtg aactgggggacatcgaatgtgggcattaaagtcggtactggtggctttaaatcgctggcc tttggtgacaataacgttatggttcatatcggtgacggtgaaagcaaacacagtgttgat atcggtggctatcaagcactggaaggtgcgcaaatgttcctcggtaaccgtaatgtgagc tttaatttcggacacagtaatgatctgatcctaatgatggataagtcgatcccaactcca ccactcgtcaatccattcgacggtgccgcacgtatttctggtgtgttgcaaggtattgct acgtctggagagggagaagattggcttgccgctcaagagcagcaatggacactgtctggc gcgaagaagttcgtcaaagatatgtctggtttggatcaaagtagcagtgtggattacacc acattagttgaattggattcacaaaatgaacgtgatagccgtggcctgaagcacgatgca gaagcgacactgaataagcaatacaatcagtggctaagcggtaacggtaatagtggcacg agtcagctcagccgcgctgataagcttcgtcaagccaatgaaaagctagcatttaacttt gccgtaggtggacaaggggcggatattcaagtcacgacgggtaactggaactttatgttc ggcgataacattcagtcgattttggataccaacttaggttcactgtttggtctcatgacg cagcagttcaccgcaacgggacaagcaaaaaccaccttcacttatacgccacaagatttg ccgcgccagctcaagaataagctactcggccagttagctggagtaggggctgaaacgaca ttggcggatatttttggtgtggattacaccgcgtcaggtcaaattgtttcgcgtaatggt caagccgtcgatggagtggcgattctcaaagagatgctggaagtcatcggtgagttcagc ggagatcaactgcaggcttttgtcgacccagctaagttactggatagcttgaaagcgggt atcgacatgggagcggatggcatcaagtcttttgctgaaactcatgggctgaaagagaaa gcgcctgaagaggaaaaggacaattcttcggtttctgttaatggtgcgaacgtgaacagt gcgcaaggtgcgactgtggctgatggcaatactgaaacagcagaaacacaagatcgtgcc tttggctttaactcgcttaacctgcctaacttgtttgcgactattttcagccaagataag cagaaggaaatgaagtcactggtggagaatcttaaacagaatctcaccgccgatctgctg aatatgaaggagaaaacgtttgatttccttcgtaatagtggccatctccaaggagatggt gatatcaacatctccctaggaaactacaacttcaactggggtggtgatggtaaagatctc ggtgcgtatctcggagataacaacaacttctggggtggacgaggcgatgatgtgttctac gcaacaggcaagtcaaacatcttcacgggtggagaaggcaacgacatgggcgttctgatg gggcgtgaaaacatgatgtttggtggtgatggcaacgacacggcagtggttgctggacgc attaaccatgtcttccttggtgctggtgacgaccagtcgtttgtctttggcgaaggtggt gaaattgataccggttcaggccgtgactatgtggtgacttctggcaacttcaaccgtgtg gatacgggagatgatcaagactactccgttacgattggcaacaataaccaagtggaactc ggagcaggtaatgactttgccaatatctttggtaactataaccgtatcaatgccggtgcg ggtaacgatgtggtgaaactgatgggttaccatgccgtgctaaacggtggtgatggagat gatcacctgattgcaacggccatctctaagttcagccagttcaacggtggtgaaggccgt gatctgatggtacttggtggttatcaaaatactttcaaaggtggcacggatgtggacagc tttgtggtgagcggtgatgttatcgacaaccttgtggaagacattcgcagcgaagataac attgtcttcaatggtatcgattggcagaaactgtggttcgagcgcagcgggtatgacctg aaactgtcgattttgcgtgatccgtctaacgacagtgaccaatcgaagtttgagcatatt ggttcggtgacattcagtgattactttaatggtaaccgcgctcaagtggttatcggaatg agtgagaaagacctgtcgggtgaacgtgaatacaccatgttatcggatagtgcgattgac gctctggttcaagcgatgagtggttttgaaccgcaagcgggtgacaatggctttatcgac agcctagagagtaaatctcaagctgcgatcagcatggcgtga

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