Vibrio cholerae O1 IEC224: O3Y_04045
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Entry
O3Y_04045 CDS
T01766
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
vci
Vibrio cholerae O1 IEC224
Pathway
vci00230
Purine metabolism
vci01100
Metabolic pathways
vci01110
Biosynthesis of secondary metabolites
Module
vci_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
vci00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
O3Y_04045
Enzymes [BR:
vci01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
O3Y_04045
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AFC57690
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Position
I:928870..932763
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AA seq
1297 aa
AA seq
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MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY
GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALT
AAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL
ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM
IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPT
AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV
NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI
RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR
CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL
EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM
PMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSV
TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI
TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS
MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL
GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA
FAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEV
EASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLN
AKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTG
QTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGC
QMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGE
GRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMM
PHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgagaattttgcgtggctccccagctctttcagagtttcgtgttaacaagctcctgacc
gcgtgtcgtgaacagcaactgcctgtaaccggtatttacgccgagtttatgcactttgcc
gatctcaaggcagagctcaatccgcaagagttggaaaagctcgaaaaactgctcacttat
ggtccaaccattcaagagcatgaaccgcaaggtttactgctgttggtgacgccgcgcccc
ggaaccatctcaccttggtcctcaaaagccaccgatattgcacacaactgtggcctgcat
ggcatcaagcgccttgagcgcggtacggcttattatgttgaagcagaaacggcgctgacc
gcagcacaaatcgcaacacttgaggcgctgctgcatgatcgaatgatggaagtcgtgttc
gcagaactcaccgatgcccagcaactgttcagcgtagcagagcctgcgcctatgagtcag
gtcgatgtattagcgggcggtcgtcgtgcgcttgaagaggcaaacgtttcccttggtctg
gcattggctgaagatgaaattgattatctggttgagagcttcactaaactgggtcgtaat
cctaacgacattgaactgatgatgtttgcacaggcgaactcagagcactgccgccacaag
attttcaacgccgattggaccattgatggggttaagcaagacaagtcactgttcaaaatg
atcaaaaacacctttgaacagacgccggattatgtgctttcggcttataaagataatgcc
gcagtaatgacgggctcgaccgttggccgtttcttccccgaccccgagagccgtcagtac
acttatcaccatgaagatgcccacattctgatgaaagtggaaacgcataaccacccaacg
gcgatttcgccttggccgggggcttcgactggttctggcggtgaaattcgtgatgagggc
gcaaccggtattggcggcaagcctaaagcgggattggtgggctttaccacctcgaacttg
cgtattcccggttttgaacagccatgggaaagcgattttggtaagccaagccgcattgtg
aatgcgctggatatcatgctggaagggccactcggcggcgcggcgttcaacaacgaattt
ggtcgcccgaacctacttgggtatttccgcacttatgaagaaaaagtgacgtcacatgct
ggtgaagaggtgcgtggttatcacaagccgatcatgattgccggcggtatgggtaacatt
cgcgccgagcatattcagaagaaagagatcccagtgggggcaaaactgatcgtactcgga
ggccctgcgatgaacatcggtctcggtggtggcgcagcctcttcgatggcttctggccag
tctgctgaagatctggattttgcttctgtgcagcgtgaaaacccagagatggagcgccgc
tgtcaggaagtgattgaccgttgttggcagctcggtgacaaaaacccgatcgcctttatc
cacgatgtgggcgcgggtggtatctctaacgctctgcctgagctggtgaatgacggcgat
cgcggtggtaaattccagttgcgcaacgtgccgaatgatgagccgggcatgagcccattg
gaaatctggtgtaatgaatcacaagagcgttatgtgctggcggttgctgcggaagatatg
ccgctgtttgatgcgatttgccagcgtgaacgcgccccttatgccgtggtaggtgaagcg
accgaagagcgccatttgacgctggaagacagccactttgctaacacgccgattgatatg
ccaatggatattctgttgggtaagccgccgaaaatgcatcgtgaagcgagcacgctgaaa
gtttcaagcccagcgctagagcgttcaggcattgagcttaatgaagcggtggatcgcgta
ctgcgtttaccggcagtcgcagaaaaaacgttcctgatcaccattggtgaccgctcagtg
actggcttagtcgcgcgggatcaaatggtcggcccatggcaagttcccgtcgcaaactgc
gcagtaacggccgcgagttttgattcttaccacggcgaagcgatgtctatgggtgagcgt
acccctgttgcgctgttggatttcggtgcctctgcacgtttagcggtcggtgaagctatt
accaacatagccgcaaccgatattggcgagctgaaacgcatcaaactttcggcgaactgg
atgtctccagcgggccatccgggtgaagatgccggtctgtatgaagcggtgaaagcggtc
ggtgaagagctttgtcctgcactgggtatcactatcccagtcggtaaagactcgatgtcg
atgaaaaccaagtggcaggaaaatggcgagcagaaagaagtgacttcgccgctgtcactc
atcatcaccgcctttgcacgtgtggaagacattcgcaagaccgtgaccccacaactgcgt
actgaccttggtgagacaagcttaatcttgattgacttggggaatggtcaaaatcgtctt
ggcgcaaccgcattggcgcaagtgtacaaacagttgggtgataagccggctgatgtggat
aacgcggcgcagctcaaaggcttttttgatgcagtacaaacgctggtgcgtaacgacaag
ctggtggcttaccacgacaaaggtgacggcggtttattggtgacgttggcagaaatggct
ttcgcgggtcactgtggtattaaagccaatattgaaaccttgggtgatgatgcactggcg
gcactgttcaatgaagagcttggcgccgtggttcaagtgaaaaatgatgagctgaatgct
gttctggcaacacttgccgcccatggtttagaagcgtgtgctcacgtgattggtgaagta
gaagcatccgatcgtctgctgatcacttgtggtgaggaagtcttgattgagcgctctcgt
actgagcttcgcaccatctgggcggaaatgacccataagatgcaagcgctgcgtgataac
tcggcgtgtgctgatcaagagtttgcggccaaacaagataaccgtgacccgggcttgaat
gcgaagttaacttacgatgtgcaagccgacgttgctgcgccgtacatcgccaaaggtgtg
cgtccgaaaatggcgattttgcgtgagcaaggcgtcaactcacacgttgagatggcggca
gcgtttgaccgcgctggttttgatgcggttgatgtgcatatgagcgacattctgactggg
caaaccgtgctcgatgcttaccaaggtctggtggcttgtggtggcttctcttacggcgac
gtactgggtgcgggcgaaggttgggcgaaatcgattctgtttaacgcccaagcgcgtgag
cagtttgagcagttcttccaacgtaaagatactttctcacttggggtgtgtaacggctgt
caaatgctgtctaacctgcgtgatttgatcccgggtgctgagctatggccacgttttgtg
cgtaacgaatcggatcgttttgaagcgcgctttagcttagtcgaagtgcaaaaatcgcca
tcgctgttctttagcgagatggcgggctcaagaatgccgattgcggtttctcatggtgaa
ggtcgtgtggaagtgcgtgatgctcagcatctggcggcaattgagcaatctggcaccgta
gcgattcgtttcgtggataactttggtcagccaacccaagcttacccaagcaacccgaac
ggttcaccgaatgcgattaccggtttaaccactcaagatggccgtgtgacgattatgatg
ccgcaccctgagcgtgtattccgtaccgtcgccaactcgtggcaccctgataactggggt
gagaatggcgcttggatgcgtatgttccagaatgctcgtaaatattttggctaa
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