Vibrio cholerae O1 IEC224: O3Y_11325
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Entry
O3Y_11325 CDS
T01766
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vci
Vibrio cholerae O1 IEC224
Pathway
vci00260
Glycine, serine and threonine metabolism
vci00261
Monobactam biosynthesis
vci00270
Cysteine and methionine metabolism
vci00300
Lysine biosynthesis
vci01100
Metabolic pathways
vci01110
Biosynthesis of secondary metabolites
vci01120
Microbial metabolism in diverse environments
vci01230
Biosynthesis of amino acids
Module
vci_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vci_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vci_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vci00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
O3Y_11325 (thrA)
00270 Cysteine and methionine metabolism
O3Y_11325 (thrA)
00300 Lysine biosynthesis
O3Y_11325 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
O3Y_11325 (thrA)
Enzymes [BR:
vci01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
O3Y_11325 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
O3Y_11325 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AFC59135
LinkDB
All DBs
Position
I:complement(2566149..2568608)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGEV
EAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNVNA
RIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRFRQAPLP
QQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIGQDTG
EDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSSEYSISF
CIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVASQFFSSL
AEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMINADQAFSLENLVAL
VQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRNVARHSR
RKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLSQATQLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELSDVDVEQALPAGFDASGSVEEFMA
RLAQADAAFAERVAQAKAEGKVLRYVAQIVDGQCQVRIVAVDENDPMFKVKEGENALAFY
SRYYQPIPLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattaaagtttggaggttcatcgctggcggatccggagcgttttctacgcgct
gccgatatcatcgcgaataacgcacagcaggaagaggtggccgttgtcctctctgctccg
ggaaaaaccaccaataaattggtggcagtgattgaaagtgctttacgtcagggagaggtg
gaagcgcaaatcgtagagctagagagctcattctatgccttgcttgatggcattaaagcg
cagctcccgaatttggatgacagtgcttatcaacagcaagtgcactcttccatgactcag
ttacgccagtttgtgcatggcattacgttgctcggtatgtgtccagacaatgtgaatgca
cgcattatcagtaaaggtgaacgcgtttccattcaattgatgaaagcggtgatggaagcc
aaaggtctgccagcgaatttggttgaccccgttaaatacctgcttgccaaaggggatcat
cttgaagctatggtcgatgtggaaatctcgactcagcgtttcagacaagcaccattgcca
caacagcacgtcaatatcatgccgggctttactgcgggtaatgcacagggtgagttggtc
tgtttagggcgtaacggttcggattactcagccgcagtactggctgcctgtttacgtgcg
gattgttgtgaaatctggacggatgtggatggagtttataactgcgatccgcgtttggtc
gatgatgcgcgtcttttgaaatcccttagctatcaagaggcgatggagctttcttacttc
ggagcatctgtgttgcatccgaagaccattgcaccgattgctcaatttcaaatcccttgc
ctgatcaaaaacagcttcaatccacaaggtgcgggcaccttgattggccaagacactggc
gaagataaactcgcgatcaaaggcattaccactctgagcaatctgaccatggtcaacgtt
tctggtccaggaatgaaaggcatggtggggatggcgagccgcgtgtttggcgcgatgtca
gcggcagatgtgtcgatcgtgctcattactcaatcttcttcggaatacagcatcagtttc
tgtatcgaagcacaacataaagctttggcacagcaagcgctggcggatgcatttgaactg
gaactcaaagatggcctgcttgagccggttgagtttgtcgataacgtcgccatcatcacg
ctggttggtgatggtatgcgtacctctcgcggtgtcgcgtcgcaatttttctcatctctg
gccgaagtacacgtcaacgtgattgcgattgcccaaggctcttctgagcgtgcgatttca
gcggtgatccccgatgataagatttcagaagcgatcaaggcctgtcacgaaaacctcttc
aactctaaacactttttagatgtgtttgtggtcggtgttggtggcgtgggcggtgagttg
gtggatcaaattcagcgtcaacaagccaagcttgcggaaaaaggcatcatgatgcgcgtt
tgtggcctcgctaacagtaaaggcatgctgcttgatagccaaggcttgccgttagagcag
tggcgcgatcgtatgatcaatgcggatcaagcgttcagtttagagaatctggtggctttg
gtgcagcgtaatcacatcattaacccagtattggtggattgcacgtccagtgatgagatt
gctaaccagtatgcggatttcctcgccgcgggtttccatgtggtgaccccgaacaagaaa
gccaataccgctagcatgagttattaccatcagctacgtaatgtggctcgtcattcgcgt
cgcaaactgatgtatgaaactacagttggcgcgggtctacccgttatcgaaaacttgcaa
aacctaattgcagcaggggatgagctggaaaaattcagcggtattctctcaggttctctc
tcctttatcttcggtaaattggatgaaggcatgaccttgagccaagcaacgcagcttgct
aaagagaaaggctttacagagccagatccgcgcgatgatctctctggtatggatgtggcg
cgcaagttactgattttggcgcgtgaagcagggtacgaattggagctgagcgatgtggat
gttgaacaagcactgcccgctggctttgatgcttcaggcagtgttgaggagttcatggct
cgtttagcgcaagccgatgccgcgtttgccgagcgagtggcgcaagccaaagccgaaggc
aaagtgcttcgctatgtggcgcaaatcgtcgatggccagtgccaagtgcggattgtcgcg
gttgatgaaaacgatcctatgttcaaagtcaaagaaggtgaaaacgcgctggctttctac
agccgttactatcagccaatcccattggtattacgtggttacggcgcgggttctgaagtg
actgctgcaggcgtgttctcagatgtgatgcgtacactcggttggaaattaggggtttaa
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