Vibrio cholerae O1 LMA3984-4: VCLMA_A1277 Help Entry VCLMA_A1277       CDS       T01871                                  Name (GenBank) RTX (Repeat in toxin) cytotoxin   KO K10953   RTX toxin RtxA Organism vcl  Vibrio cholerae O1 LMA3984-4 Brite KEGG Orthology (KO) [BR:vcl00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:vcl02042]     VCLMA_A1277 Bacterial toxins [BR:vcl02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    VCLMA_A1277 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACD RtxA Peptidase_C80 MLD RtxA_C Abhydrolase_1 Hydrolase_4 Abhydrolase_6 Abhydrolase_3 DUF1057 Thioesterase DUF4105 Motif Other DBs NCBI-ProteinID:  AEA78516 LinkDB All DBs Position I:1446033..1459670 Genome browser AA seq 4545 aa AA seqDB search MGKPFWRSVEYFFTGNYSADDGNNNIVAIGFGGQIHAYGGDDHVTVGSIGATVYTGSGND TVVGGSAYLKVEDSTGHLTVKGAAGYADINKSGDGNVSFAGAAGGVSIDHLGNHGDVSYG GAAAYNGITRKGLSGNVTFAGAGGYNALWHETNQGNLSFTGAGAGNKLDRTWFNRYQGSH GDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGDITLQGAGASNRIERTHQA EDVYTQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNTIIRKGSGNDFAKEGMTNAK ADEIVLTKAVMSGSWIGQDHHVTAVKSASEPNTYLFAFADSTYTKINKVQLRNDPQTGEL KYYSTAWYKEGNHLSNLANQDISDNGGFTAVNINGAYTLSDLKVEHQQSVTVHAVEKSLT EYEWVTYANGAVIDAKEVSLSDAKMGGHAIYADGTKVDVKAVKSNRQPNTYIYAKVLGPY TKIVVVELANDPETGALKYQARSWYKEGDHTANIANQDISSATGYNPMGKGGYSLSDLHY SVNAVRSTSETVADIEEYTDQTLFKPANDSGESSGDVRFNGAGGGNVIKSNVTRGNVHFN GGGIANVILHSSQFGNTEFNGGGAANVIVKSGEEGDLTFRGAGLANVLVHQSQQGKMDVY AGGAVNVLVRLGDGQYLAHLLAYGNISVQKGSGDSRVVMLGGYNTNTQIGSGNGLWLAAG GFNVMTQVGQGDVAAVLAGGANVLTKMGEGELTSGMLGGANVLTHISNDDQLSNTTAVAL GGANILTKKGKGNTLAVMGGGANVLTHVGDGTTTGVMVGGANILTKIGNGDTTGIMLGVG NVLTHVGDGQTLGVMGAAGNIFTKVGDGTSIAVMIGAGNIFTHVGEGNAWALMGGLGNVF TKVGNGDALALMVAEANVFTHIGDGMSVALMLAKGNVATKVGNGTTLAAMVGNANIFTHV GSGSTFAAMIGQANIMTKVGNDLTAALMVGKANIMTHVGDGTSLGLFAGEVNVMTKVGNG TTLAAMFGKANIMTHVGDGLTGVLALGEANIVTKVGDDFMGVVAAAKANVVTHVGDATTA AVLAGKGNILTKVGEGTTVGLLISDVGNVMTHVGDGTTIGIAKGKANLITKVGDGLGVNV AWGQANVFTQVGDGDRYNFAKGEANLITKVGDGQEVSVVQGEANIITHVGNGDDYTGAWG KANVITKVGHGQNVVLAKGEANIVTQVGDGDSFNALWSKGNIVTKVGDGMQVTAAKGQAN ISTTVGNGLSVTAAYGDANINTKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANI HVGDGLNINASYAQNNVAIKVGNGDFYSLAVASSNTSSNKLSALFDNIKQTVLGVGGSQA INYLVQGDEASSSGTHKGRGAIATPEITKLDGFQMDAIKEVGSDLGDSLTGSVTKVDTPD LNKMQHALNVDDSSVQAPNLIVNGDFELGEHGWQSTHGVEASYAGSVYGVEGEGHGARVT ELDTYTNTSLYQDLANLAQGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDESAW QQKTLKLTAQAGSNRIEFKGTGHNDGLGYILDNVVATSESSQQANAIREHATQNPAAQNA LSDKERAEADRHRLEQEKQKQLDAVAGSQSQLESTDQQALGNNGQAQRDAVQEESEAITA ELTKLAQGLDVLDGQATHTGESGDQWRNEFASGLLAGVQTQLDDAKQLANDKIAEAKQTH ADNQNKVKDAVAKSEAGVAKGEQNRAGAEQDIADAQADAEKRKADALAKGKDAQQAESDA HHAVNNAQSRGDRDVQLAENKANQVQADAQGAKQNEGDRPDRQGVTGSGLSGNAHSVEGA GETDSHVNTDSQTNADGRFSEGLTEQEQEALEGATNAVNRLQINAGIRAKNSGSSMTSMF SETNSKSIVVPTKVSPELERQEVTRRDVRISGVNLESLSAVQGSQPTGQLASKSVPGFKS HFASTSIGIENELSGLVVVLPKNSAQTFGYVHDSQGNPLFMLTKDMNQGGYSNPVGINDI QGVNNWQTHTIELVTYPSEISDTAAIESRKEAMLWLAKEFTEHINQSNHQSLPHLVSDDG RFTLVISNSKHLIAAGNGTSIDAQGKTIGMTPSGQQATMAISAKEFGTSSSPEVRLLESA PWYQAGLRDEFLANAKNTTLDDPATAQNVYAYLTSVYSKTADLAKEYGIYINDWDPASEG FSPNAQGLTDPKVKNAWSILPRTKPVRMLELLSAEDSRYVRQQIAEKLKGTYSESLAKNV FEYFQYGGEVAGHGINNATTGSVQQPEPAILFEFRSVPSALSDFVPKTASTVKVDVKALD HFDSASRKAIITEVNALVSGSEDFDAWYQEYRASKGQPPVKNPKSSASANHKAEWLMTQH AEQWAKITAPYTDNHETLTSTKLASNDKEELHALGETSNLENNKQQENVASIINTMLNDM LPFYALRTERNLLVQEGDEGFEVRAWPGTEDKSKTIILENPEDAAQHKAIERFILANFDN FEQMPDELFLVDNKVISHHEGRTHVLAQKVDGAWQYNAKVELMSVTELLDAANVTGKIRG ESYQQVIDALTDYHASITEHADYEPESVEKLLNLRKKIEGYVLGHPDSGRVEAMNSLLNQ VNTRLDEVSLLSVAEQTIQAQNSFSRLYDQLEAANLKESKHLYLDQNGDFVTKGKGNLAN IDLLGSREAVLEKVKLTVSNEYGQTVADTIFAGLSAKDLAKDGKGIDIAGLNKVHQAIEQ HLSPVSATLYIWKPSDHSALGHAALQIGQGRTQLEGQAAADFNQQNYVSWWPLGSKSSNI SNILNVATKDQPDLKLRWSDFSQPAHQNDTLEHDVASEENDGFGLHDGDIKLKRFIEKLN AAKGIDASFKEASEGYASVLLGNPDMLETTSIPAHVFQPFVEQWNDTSYDMMDVANRFAQ ELRLQAQRSDDPELLEKRIGNVVRQFAERALEEIETFKASQADQGRVFRINLEGLDVAAM QAEWHRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWLPKFGVWTPTELFNFGQ ALQEAQLEIAAKKQSHQVTDVLDALSGNEKPKENVAIENDGTPPRDKESLSPLTRFLNNE LYGDKEARRKIGEITQTLLDHAVENGESQKVTLKGEAGRLTGYYHQGAVSSEGETSATSG KVVLFLHGSGSSAEEQASEIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTMFN YLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITAHEV ANPAGIVGAIAKAVNGQFSVEKNLEGLPKETSILLLTDNEGLGNEGEKLRTKLTASGYNV TGEQTFYGHEASNRLMSQYADQIVSGLSSSASVDEDLDQQGLDTTSTKDQGISNKNDHLQ VVDSKEALADGTILHNQDVNSWGPITVTPTTDGGETRFDGQIIVQMENDPVVAKAAANLA GKHAESSVVVQLDSDGNYRVVYGDPSKLDGKLRWQLVGHGRDHSESNNTRLSGYSADELA VKLAKFQQSFNQAENINNKPDHISIVGCSLVSDDKQKGFGHQFINAMDANGLRVDVSVRS SELAVDEAGRKHTKDANGDWVQKAENNKVSLSWDAQGEVVAKDERIRNGIAEGDIDLSRI GVSDVDEPARGAIGDNSDVFDAPEKRKPETEVIANSSSSNQLSYSGNIQVNVGEGEFTAV NWGTSNVGIKVGTGGFKSLAFGDNNVMVHIGDGESKHSVDIGGYQALEGAQMFLGNRNVS FNFGHSNDLILMMDKSIPTPPLVNPFDGAARISGVLQGIATSGEGEDWLAAQEQQWTLSG AKKFVKDMSGLDQSSSVDYTTLVELDSQNERDSRGLKHDAEATLNKQYNQWLSGNGNSGT SQLSRADKLRQANEKLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMT QQFTATGQAKTTFTYTPQDLPRQLKNKLLGQLAGVGAETTLADIFGVDYTASGQIVSRNG QAVDGVAILKEMLEVIGEFSGDQLQAFVDPAKLLDSLKAGIDMGADGIKSFAETHGLKEK APEEEKDNSSVSVNGANVNSAQGATMADGNTETAETQDRALGFNSLNLPNLFATIFSQDK QKEMKSLVENLKQNLTADLLNMKEKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDL GAYLGDNNNFWGGRGDDVFYATGTSNIFTGGEGHDMGVLMGRENIMFGGDGNDTAVVAGR INHVFLGAGDDQSFVFGEGGEIDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVEL GAGNDFANVFGNYNRINAGAGNDVVKLMGYHAVLNGGDGDDHLIAAAISKFSQFNGGEGR DLMVLGGYQNTFKGGTDVDSFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDL KLSILRDPSNDSDQSKFEHIGSVTFSDYFNGNRAQVVIGMSDKDLSGEREYTMLSDSAID ALVQAMSGFEPQAGDNGFIDSLESKSQAAISMAWSDVVHKKGLMV NT seq 13638 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaccattttggagaagtgttgaatacttcttcacaggaaactattccgccgac gatggaaacaacaacattgtagccattggttttgggggacaaattcatgcctacggcggt gacgaccacgtcactgttggatcgattggtgcaacggtgtacaccggtagcggcaacgat acggtcgtgggcggctctgcctatctcaaagtggaagattccactggccacctaactgta aaaggcgcggctgggtatgcagacattaataaaagtggcgatggtaatgtgtcattcgct ggtgccgccggtggtgtgtcgattgaccacttaggtaatcatggtgatgtcagttacggc ggtgccgcggcttataatggcattacccgtaaagggttgagcggtaatgtcacctttgca ggcgcagggggatacaatgccctctggcatgaaaccaaccaagggaacctgtcttttaca ggagcaggcgcaggtaataaattagaccgtacttggtttaaccgttatcaaggctcgcat ggcgatgtgacctttgatggtgccggtgccgcgaacagcatcagttcacgcgttgaaacc ggtaacatcaccttccgtggcgcaggtgcggataaccatttagtccgtaaaggcaaagtg ggcgatattactctgcaaggtgcaggggcttcaaaccgcattgagcggacacatcaggcc gaagatgtctacacacaaacccgcggcaatattcgttttgaaggtgtgggtggttacaac agtctttactctgatgtggctcatggtgacattcatttctcggggggcggtgcgtacaac accattattcgtaaaggttctggaaatgactttgcgaaagaaggcatgaccaatgctaag gctgatgagattgtattaactaaggccgtaatgagtggctcatggatagggcaagatcat catgtcacagcggtgaaatcggctagcgagcctaatacatatctttttgctttcgcagac tctacgtataccaaaattaacaaagtacagttacgcaatgatcctcaaactggagaactg aaatattactctacggcttggtataaagagggtaaccatctaagtaacttagcgaatcaa gacatttccgacaacggtggtttcacagccgttaatatcaatggcgcctacacgctatct gacctcaaagttgaacatcagcaatccgtcaccgttcatgcggttgaaaaaagtctgacg gaatatgagtgggtgacttacgccaatggtgcggtgattgatgcgaaagaggtgtcattg tcggatgccaaaatgggcggtcatgcgatttatgctgatggcactaaggtggatgtcaaa gcggtaaaatccaatcgccaacccaacacttacatttatgccaaagtgcttgggccttac acaaaaattgtggtggtggaactggcaaacgatcccgaaaccggggcactgaaatatcaa gctcgctcttggtataaagaaggtgatcacacggccaatatagccaaccaagatatttca tctgcaactgggtataacccaatgggcaaaggcggctactcgctcagtgacttgcactac agcgtaaacgccgttagaagtaccagcgaaaccgtagcggatatcgaagaatacacagat caaacgttgtttaaacccgcaaacgatagcggtgaaagctcaggtgatgttcgtttcaac ggtgccggtggcggtaacgtcatcaaatcaaacgtgacgcgtggtaatgtgcatttcaac ggtggcggtattgccaacgtgattttgcatagctcccaatttggtaataccgaatttaac ggtggtggtgcggcgaacgtcattgtcaaaagtggcgaagaaggggatctcaccttccgc ggcgcaggtttggcgaacgtcttggtacaccaaagccaacaaggcaagatggatgtgtac gcgggcggtgcggtaaacgtgttggttcgccttggcgatgggcaatatctcgcgcattta ctggcttacggtaacatttcagtccaaaaaggcagtggtgatagtcgcgtcgtgatgctc ggtggctacaacaccaatacccaaatcggctctggcaacggattatggttggcggcgggc ggtttcaacgtgatgacgcaagtcggccaaggtgatgttgctgcggtactcgctggcggt gcaaacgtactgaccaaaatgggtgagggtgaactcacgtcgggtatgctgggtggcgcg aacgtactaacccacatcagcaatgatgatcaattatcgaataccacggctgtggcactt ggcggtgcaaatattctcaccaaaaaaggcaaagggaatacccttgcggtgatgggtggt ggcgcaaacgtgcttacccatgttggtgatggcaccacaacgggtgtcatggtcggcggc gcgaacatcctaacgaaaatcggaaatggcgacacgaccggcattatgcttggcgttggc aacgtgctgacgcatgtgggtgatggccaaacccttggcgtaatgggcgcggcgggtaac atcttcaccaaagtgggtgatggaacctctattgcggtcatgattggtgctggcaacatt tttacccatgtgggagaagggaatgcttgggcgctgatgggcggcttgggtaacgtcttt accaaagtaggcaacggtgatgctctcgcgttaatggtagcagaagccaacgtcttcact cacattggtgatggcatgtcggtggcactgatgttagccaaaggtaacgttgcgacaaaa gtgggtaatggaaccacactcgctgcaatggttggtaacgccaatatcttcactcacgta ggcagtggcagcacgtttgcggcgatgatcggccaagccaatatcatgaccaaagtaggc aatgatctcacggcggcgctgatggtcggcaaagcgaacatcatgacccatgttggcgat ggtaccagcctagggctgtttgctggcgaagtgaacgtgatgactaaggttggtaacggc accacgttagcggcgatgttcggtaaagcgaacatcatgacccatgtcggtgatggctta accggtgtactcgcactgggtgaagccaatatcgttaccaaagtgggtgatgatttcatg ggtgtggtggccgcggccaaagccaacgttgtgactcatgttggtgatgctaccaccgca gccgtattggcgggtaaaggcaatatcctcaccaaggtgggtgaaggtacaaccgttggt ttattgatctccgatgtcggcaacgtgatgacccacgttggtgacggcaccaccattggt attgccaaaggtaaggccaacctcattaccaaagtcggtgatggtttaggtgttaatgtc gcttgggggcaagccaacgtgtttacccaagtgggcgacggtgatcgctataactttgcc aaaggtgaagccaacctcatcaccaaggtgggtgatggtcaagaagtctccgtggtgcaa ggcgaagccaacatcattactcatgtgggcaatggcgacgactacaccggagcttggggt aaagcgaacgtcattaccaaagtgggtcatggccaaaacgtggtactggcaaaaggtgaa gccaacattgttactcaagtgggtgatggcgacagctttaacgcactttggagcaaaggc aacatagttaccaaagtgggcgatggtatgcaggtgacggcagcaaaaggccaagccaat atctccaccaccgtgggtaacggtctaagtgtcactgcagcctacggcgatgccaatatc aacaccaaagtcggtgatggggtatccgtcaacgtcgcttggggcaaatataacatcaac acgaaagtgggtgatgggctgaatgtcgctgtgatgaagggcaaagctaacgccaatatt cacgttggggacggcctcaacatcaatgcctcctacgcacaaaacaacgtcgccatcaaa gtcggtaacggcgatttctacagcttagcggtggcatcaagcaataccagcagcaacaag ctctctgccttgtttgataacatcaaacaaaccgtactcggtgttggtggcagccaagcc atcaactacttagtgcaaggcgatgaagcctcctcatccggcacgcataaaggtcgtggt gcgattgcaacacctgaaatcaccaaactggatggtttccaaatggatgccattaaggaa gtcggttccgacctcggtgatagtctcacgggcagcgtgactaaggtagatactcctgat ctcaacaagatgcagcatgcgctcaatgttgatgattcttccgttcaagctccgaatctg attgtgaatggggattttgagctgggcgaacatggctggcaatctactcatggggttgaa gcctcttatgcaggcagtgtgtatggcgtagagggtgaaggtcacggcgcacgtgtgacc gagctcgatacttataccaacaccagtctctatcaagatctggctaatctagcgcaaggt gaagtcattgcggtgagctttgattttgcaaaacgcgcgggcctttctaataacgaaggc atcgaagttctttggaacggtgaagtggtattctcatcgtcgggtgacgagtctgcttgg cagcaaaaaaccttaaagctgaccgcgcaggctggcagtaaccgtatcgaattcaaaggc acaggccacaatgatggactgggctacatcctagataatgtggtggcgacctcagagtca tcgcaacaagccaatgcaatccgtgagcacgcaacgcaaaacccagcagcgcagaatgct ctatccgataaagagcgtgcagaagcggatcgccatcgtctagaacaagaaaaacagaaa cagcttgatgctgtcgcaggttcacaaagtcagttggagtcgaccgaccaacaagcgtta ggaaataacggtcaagctcaacgtgatgcggtgcaagaagaatcagaagctatcacggct gagttgacaaaactggcgcaaggtctcgatgtgcttgatggccaagcaacgcatactggc gagtcaggcgaccaatggcgtaacgaatttgctagcggtctgctggctggcgttcaaact caactcgacgatgcgaagcagctcgcgaatgacaagattgctgaggcgaagcagacgcac gcggacaatcaaaataaagtgaaagatgcggttgcgaagtctgaagcgggagtcgccaaa ggcgagcaaaatcgagcgggagcagagcaagatattgctgatgctcaagccgatgctgaa aaacgtaaagccgatgctttagcaaaaggtaaggatgcgcaacaagcggaatctgatgca catcatgcggtaaataacgctcaatcacgcggcgatcgtgatgtgcaattggcggaaaac aaagccaaccaagtacaagccgatgctcaaggtgctaaacaaaacgaaggtgatcgtcct gatcgtcaaggcgtgactggtagtggcctttcgggtaacgctcatagcgtggaaggcgct ggcgaaacagacagtcatgtcaacaccgacagccaaaccaacgccgatggccgattcagt gaaggtttgaccgaacaagagcaggaagcgctagaaggtgcgaccaacgcagtgaaccgt ttgcaaattaacgcaggtattcgagcgaaaaacagcggtagcagtatgacttctatgttc tctgaaacaaatagcaagagcattgttgttcctaccaaagtctcgcctgaactagagcgc caagaagtgactcgtagagacgtccgtatctcaggggtgaacctcgaaagtctaagtgcg gtacagggaagtcaaccaacgggtcaactggcttcgaaaagtgtccccggatttaaaagc catttcgcatcgacatccattggtatagaaaatgagctatccggtctggtggtggtttta ccgaaaaactcagcgcagacttttggctatgtgcatgattcacaaggtaacccattgttc atgctaaccaaggatatgaatcaaggtggttatagcaacccagtgggtatcaatgatatt caaggggtgaacaactggcagacgcatacgattgaactggttacatatcctagtgaaatc agtgatacagcagcaattgaaagtcgtaaagaggcaatgctatggcttgcgaaagagttt accgaacatatcaatcagtctaaccaccaaagcttacctcatttagtgagtgatgacggg cgtttcactctggttatatcgaactctaagcatcttattgcggcgggtaacggaacctct attgatgcacaaggcaagaccataggaatgacccctagtggccaacaagcaacaatggcg atcagtgcgaaagaatttggtacaagctcgtcgccggaagtcagactgcttgaatctgcg ccttggtatcaagcagggttgagagatgagtttttagcaaacgcgaaaaacaccacgttg gatgatcccgctacagcacaaaatgtgtatgcctatctcacgtctgtctattcaaaaaca gcagatttggccaaagagtatgggatctacatcaatgattgggatcctgcctctgaaggt ttttcaccgaatgctcaagggttaacggatccgaaagtcaaaaatgcttggagcatattg ccaagaactaaacccgttagaatgctggaacttctgagtgcggaagactcacgctacgta aggcaacaaattgcggaaaagctgaaaggcacctattcagaaagccttgctaagaacgtg tttgaatacttccaatatggtggagaagtcgctggacatggaatcaataatgcgacgaca ggaagtgtgcaacagcctgaaccagcgatcttatttgagtttcgcagtgtaccgagtgca ttaagtgactttgtacccaaaacagcgtcaacggtgaaagtggatgttaaggcactcgat cattttgactcggcaagccgtaaagccatcattactgaagtaaatgctttggttagcggt agtgaggatttcgatgcttggtatcaggagtatcgagcaagcaaaggacagccgccagtc aaaaatcctaagtccagtgcatccgccaatcacaaagctgaatggttgatgacgcagcat gctgaacaatgggcgaaaattaccgctccttatactgataaccatgagacgctcacatct accaagcttgcttctaacgataaagaagaattacacgctttaggtgaaacgtcgaatcta gagaataacaagcagcaagaaaacgtcgcttccataattaacaccatgttaaatgacatg ctgccattctatgcactgcgtaccgaacgaaatctactggtacaagaaggagatgaaggc ttcgaagtgcgtgcttggccaggaaccgaagacaagagtaaaaccattattcttgagaac cctgaagacgcggctcagcacaaagccatcgaacgcttcattctggccaacttcgataat ttcgaacaaatgccagacgagctcttcttggtggataacaaggtgatttcacaccatgaa ggtcgtacacatgtgttggcgcaaaaagtcgatggtgcgtggcaatacaacgccaaagtg gagctgatgtcagtcactgaactactggatgcggcgaatgtaacgggtaagatccgcggt gaaagctatcagcaagtgatagacgcattgactgattaccacgccagcatcactgagcac gcagattatgaaccggagtccgtggaaaaactgctcaacttgcgtaaaaaaattgaaggc tatgtacttggacacccagactcaggccgtgttgaagcgatgaattcactgttaaatcag gtgaatacgcgtttagatgaagtttcactgctgtcagttgctgagcaaactatccaagcg caaaacagtttcagccgactatatgaccagctagaagccgctaacttgaaagagagtaaa cacctttatctggatcaaaatggtgactttgttaccaaaggcaaaggtaatcttgccaat atcgatctgctaggtagccgcgaagctgtgcttgaaaaagtgaagttaacagtaagtaac gagtacggtcaaaccgttgcggatacaatttttgctggattatcagccaaagatcttgcc aaagacggtaaagggattgatatcgcgggtttgaataaagtacaccaagcgattgaacag catctgtcacctgtcagcgccaccttgtacatttggaaaccgagtgatcatagcgcgcta ggtcatgccgcattgcaaataggccaaggtcgcacgcaacttgaaggtcaagccgcagct gattttaaccagcaaaattacgtaagctggtggccactaggcagcaagtcatccaatatc agcaatatcttgaatgtggccacaaaagaccaacctgatcttaagctgcgctggagcgac ttcagtcaacctgcacatcaaaatgacacgcttgagcatgatgttgcttcggaagaaaac gatggctttggtttgcatgatggcgacattaagctgaaacgctttatcgagaagctcaat gccgcgaaaggaattgacgcttcatttaaagaggcttctgaaggttacgcgagcgtacta ctgggtaacccagatatgctcgaaacgacaagtattccagcacatgtttttcaaccattt gtcgaacaatggaatgacaccagttatgacatgatggacgtggcaaaccgttttgcgcaa gagctcagactacaggctcaaagaagtgacgatcccgaactgcttgaaaagcgcatcggc aatgtggttcgccaatttgcagaaagagcactggaagagatcgaaaccttcaaagcaagc caagccgatcaaggtcgagtattccgcattaaccttgaaggcctcgatgtggcggcaatg caagcagaatggcatcgtctaagcaacgatccggatgctcgctatcaattactgaccaaa aactgctccagcacggtggctaaagtgttgaaagccggcggggcggataaactgattggc catacatggctgcctaagtttggtgtttggacgccgaccgagcttttcaactttggtcag gcactgcaggaagctcagcttgaaattgctgcgaagaagcaaagtcatcaagtcactgat gtccttgatgccttgtcaggcaatgagaagcctaaagaaaacgtggcgattgaaaatgat ggtacgccaccgcgcgataaagaatctctgagtccattgactcgatttctcaataacgag ttgtatggtgataaagaggctcgccgtaagattggcgaaatcacgcaaaccttacttgac catgcggtagaaaatggagaatcgcagaaagttaccctcaaaggggaagcgggtcgtcta acggggtattaccatcagggagcggtttcaagcgaaggtgaaacaagcgcgaccagcggc aaagtcgtgttgttcttgcacggttctggttcttctgctgaagagcaagcgagcgagatt cgcaaccactaccaaaaacaaggtatcgacatgctcgcagtcaacctgcgtggctatggt gaaagcgacggtggaccaagcgaaaaaggcttgtaccaagatgctcgcaccatgttcaac tacctagtgaatgataagggtattgacccaagcaacatcatcattcacggctactcaatg ggcggtccaattgccgcagatttagcacgttatgccgcgcaaaacggccaagcggtgtcg ggcttattgcttgaccgtcctatgccaagcatgaccaaagccatcaccgctcacgaagtg gcgaatccagcgggcattgtgggggctatcgcgaaagcggttaacggccagttctctgta gagaaaaatctcgaaggtttgccaaaagagacatccattctgctgttgaccgataacgaa ggtttgggtaacgaaggtgagaaacttcgtaccaaactcactgcctctggttacaacgtc actggtgagcagacattctatggtcacgaagcaagcaaccgtttgatgagtcaatatgcg gatcaaattgtctccggtttgtccagcagtgcaagtgtagatgaagacctagatcaacaa gggttggataccacatcaaccaaggatcaaggcatctcaaataagaatgatcatctgcaa gtggtggatagtaaagaagcattagcggatggaacaatactccataatcaagatgttaat agctggggcccgattacggttacaccaacgacagatggtggtgaaacccgcttcgacggt caaatcatcgttcaaatggaaaacgacccggtagtagcaaaagcggcagccaatttagca ggtaaacatgctgaaagcagtgtggtggtgcagctcgattcagacggcaactatcgcgtg gtgtatggcgatccgtcaaaactggatggaaagctacgttggcagttggtggggcatggt cgcgaccactcagaaagtaacaatactcgcttaagtggttacagtgccgatgagttggcc gtgaaattggccaagttccaacagtcgtttaatcaagccgaaaacatcaacaacaaaccg gatcacatcagtattgttggttgttctttggtgagtgacgacaagcaaaaaggctttggt catcagtttattaacgcgatggatgcgaatggtcttcgtgtcgatgtctctgttcgtagt tctgaactggccgtagacgaagcgggacgtaagcataccaaggacgcgaatggagattgg gttcaaaaggcagaaaacaacaaagtttcgctaagctgggacgcgcaaggtgaagttgtt gccaaggatgaacgtattcgcaatggtattgcggaaggcgacatcgatctctctcgtatt ggtgtcagcgacgttgatgagcctgctcgtggcgcgatcggagacaatagtgacgtgttt gatgcgccagaaaaacgcaaaccagaaacggaagtgattgccaattctagcagcagtaat caactcagctactcaggtaacattcaagttaacgtgggcgaaggggagtttacggcggtg aactgggggacatcgaatgtgggcattaaagtcggtactggtggctttaaatcgctggcc tttggtgacaataacgttatggttcatatcggtgacggtgaaagcaaacacagtgttgat atcggtggctatcaagcactggaaggtgcgcaaatgttcctcggtaaccgtaatgtgagc tttaatttcggacacagtaatgatctgatcctaatgatggataagtcgatcccaactcca ccactcgttaatccattcgacggtgccgcacgtatttctggtgtgttgcaaggtattgct acgtctggagagggggaagattggcttgccgctcaagagcagcaatggacactgtctggc gcgaagaagttcgtcaaagatatgtctggtttggatcaaagtagcagtgtggattacacc acattagttgaattggattcacaaaatgaacgtgatagccgtggcctgaagcacgatgca gaagcgacactgaataagcaatacaatcagtggctaagcggtaacggtaatagtggcact agtcagctcagccgcgctgataagcttcgtcaagccaatgaaaagctagcatttaacttt gccgtaggtggacaaggggcggatattcaagtcacgacgggtaactggaactttatgttc ggcgataacattcagtcgattttggataccaacttaggttcactgtttggtctcatgacg cagcagttcaccgcaacgggacaagcaaaaaccaccttcacttatacgccacaagatttg ccgcgccagctcaagaataagctactcggccagttagcaggagtaggggctgaaacgaca ttggcggatatttttggtgtggattacaccgcgtcaggtcaaattgtttcgcgtaatggt caagctgtcgatggagtggcgattctcaaagagatgctggaagtcatcggtgagttcagc ggagatcaactgcaggcttttgtcgacccagctaagttgctagatagcctgaaagcgggt atcgacatgggagcggatggcattaagtcttttgctgaaactcatgggctgaaagagaaa gcgcctgaagaggaaaaggacaattcttcggtttctgttaatggtgcgaacgtgaacagt gcgcaaggtgcgactatggctgatggcaatactgaaacagcagaaacacaagatcgtgcc cttggctttaactcgcttaacctgcctaacttgtttgcgactattttcagccaagataag cagaaggaaatgaagtcactggtggagaatctcaaacagaatctcactgctgatttgttg aacatgaaggagaaaacgtttgatttccttcgtaatagtggccatctccaaggagatggt gatatcaacatctccctaggaaactacaacttcaactggggtggtgatggtaaagatctc ggtgcgtatctcggagataacaacaacttctggggcggacgaggcgatgatgtgttctac gcaacaggcacgtcaaacatcttcacgggtggagaaggccacgacatgggcgttctgatg ggacgtgaaaacattatgtttggtggcgatggcaacgacacagcagtggttgctggacgc attaaccatgtcttccttggtgctggtgacgaccagtcgtttgtctttggcgaaggtggt gaaattgatacagggtcaggccgtgactatgtggtgacttctggcaacttcaaccgtgtg gatacgggagatgatcaagactactccgttacgattggcaacaataaccaagtggaactc ggagcaggtaatgactttgccaatgtctttggtaactataaccgtatcaatgccggtgcg ggtaacgatgtggtgaaactgatgggttaccatgccgtgctaaacggtggtgatggagat gatcacctgattgcagcggccatctctaagtttagccagttcaacggtggtgaaggccgt gatctgatggtacttggtggttatcaaaatactttcaaaggtggcacggatgtggatagc tttgtggtgagcggtgatgttatcgacaaccttgtggaagacattcgcagcgaagataac attgtcttcaatggtatcgattggcagaaactgtggttcgagcgcagtgggtatgacctg aaactgtcgattttgcgtgatccgtctaatgacagtgaccaatcgaagtttgagcatatt ggttcggtgacattcagtgattactttaatggtaaccgcgctcaagtggttatcgggatg agtgataaagacctgtcgggtgaacgtgaatacaccatgttatcggatagtgcgattgac gctctggttcaagcgatgagtggttttgaacctcaagcgggtgacaatggctttatcgac agcctagagagtaaatctcaagcagcgatcagcatggcgtggtcagacgtggttcacaaa aaaggattgatggtgtaa

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