KEGG   Vibrio cholerae O1 2012EL-2176: EN18_15475
Entry
EN18_15475        CDS       T03389                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
vcq  Vibrio cholerae O1 2012EL-2176
Pathway
vcq00290  Valine, leucine and isoleucine biosynthesis
vcq00620  Pyruvate metabolism
vcq01100  Metabolic pathways
vcq01110  Biosynthesis of secondary metabolites
vcq01210  2-Oxocarboxylic acid metabolism
vcq01230  Biosynthesis of amino acids
Module
vcq_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:vcq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    EN18_15475
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    EN18_15475
Enzymes [BR:vcq01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     EN18_15475
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2 NAD_binding_10 IPMS_D2
Other DBs
NCBI-ProteinID: AIT30424
UniProt: A0A0H6XI14
LinkDB
Position
1:2140732..2142282
AA seq 516 aa
MNNQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDIIEAGFPVSSPGDFESVQT
IAKNIKNSRVCALSRAVAKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVA
MAVKAVKHARQYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEF
GGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAIQAGARQVEGTINGIGERAGNCA
LEEIAMIIKTRQELLGVTTGIKHDEISRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIH
QDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYNENEYNLDALYEDF
LKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSIKLLCGGEEKCE
AAVGNGPVDALYQCIYRITGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVS
TDIVEASGQALLHVINSIHRADQIAQIKQKKSVATV
NT seq 1551 nt   +upstreamnt  +downstreamnt
atgaacaatcaggtgattatattcgataccacattacgcgatggagagcaggctttgtct
gccagcctgacggtaaaagagaaactgcaaatcgcctacgcactggagcgcttaggggta
gatattatcgaagcaggtttccctgtttcctctccgggcgattttgaatcggtacaaacc
atcgctaaaaacatcaaaaatagccgtgtttgtgccctttcgcgagccgttgcgaaagac
attgatgccgcggcagaagccttgaaagtcgccgaagcctttcgtattcacacttttatc
tccacatccactatccatgtacaagacaaattgcgccgcagctatgacgatgtcgtcgca
atggcagtcaaagcggtgaaacatgcgcgtcaatatacggatgatgtggagttctcttgt
gaagatgctggccgcacacctatcgataacttgtgccgtatggtcgaagccgcgatcaat
gccggtgcgcgtaccatcaatattccagatacggtcggctacacagtgccgagcgaattt
ggcggcattattcaaacgctgtttaaccgagtgcccaatatcgataaagcgatcatctcc
gtgcattgtcatgacgacttaggcatgtcggtagccaactcgattgccgctattcaagcg
ggagctcgtcaagtagagggaaccatcaacggtattggcgaacgtgcgggtaactgcgca
ttggaagagatcgcgatgatcatcaaaacccgtcaagagttgctcggggtaaccacaggc
attaaacacgacgagatcagccgtaccagcaagcttgtcagccagctatgcaacatgccg
attcaaagcaacaaagcgattgtcggagccaatgcgtttagccactcttcgggcattcac
caagatggcatgctcaaaaacaaaaatacctacgaaatcatgacccccgaatcgataggc
ctcaaaaaccaagcactgaacctcactagtcgtagtgggcgtgccgcagtgaaaagccat
atggattcaatgggctacaacgaaaatgaatacaatttggatgccttgtatgaagacttc
ttgaagctggcagatcgcaaaggccaagtgtttgattacgatttagaggccttgatgcat
ttctctaatttgcgtgaagaagatgacttctacaaactcaattacttgagcgtgcaatcg
ggtagcgtgatggccaccaccagtattaagttgctgtgtggcggtgaagaaaaatgcgaa
gccgctgttggtaatggtccagtcgatgcgttatatcagtgtatctatcgcatcacaggg
tatgagattgtactcgataaattcgatctcaccgccaaaggcgaaggtgaagatggtctt
ggtcaagcggatatcatcgccaactacaaaggacgtaaatatcacggtaccggcgtctca
accgacatcgttgaagcttccggtcaagccttgttgcatgttatcaatagcattcatcgc
gcggatcaaatcgcccagattaaacagaaaaaaagcgtcgctacggtttaa

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