Vibrio cholerae O1 O395: VC395_2479
Help
Entry
VC395_2479 CDS
T02099
Symbol
thrA
Name
(GenBank) threonine-sensitive aspartokinase I/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vcr
Vibrio cholerae O1 O395
Pathway
vcr00260
Glycine, serine and threonine metabolism
vcr00261
Monobactam biosynthesis
vcr00270
Cysteine and methionine metabolism
vcr00300
Lysine biosynthesis
vcr01100
Metabolic pathways
vcr01110
Biosynthesis of secondary metabolites
vcr01120
Microbial metabolism in diverse environments
vcr01230
Biosynthesis of amino acids
Module
vcr_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vcr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vcr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vcr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VC395_2479 (thrA)
00270 Cysteine and methionine metabolism
VC395_2479 (thrA)
00300 Lysine biosynthesis
VC395_2479 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VC395_2479 (thrA)
Enzymes [BR:
vcr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VC395_2479 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VC395_2479 (thrA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ACP10469
UniProt:
A0A0H3ALP0
LinkDB
All DBs
Position
I:complement(2604503..2606980)
Genome browser
AA seq
825 aa
AA seq
DB search
MHLEEGMRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESA
LRQGEVEAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMC
PDNVNARIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRF
RQAPLPQQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYN
CDPRLVDDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTL
IGQDTGEDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSS
EYSISFCIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVAS
QFFSSLAEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVG
GVGGELVDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMVNADQAFSL
ENLVALVQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRN
VARHSRRKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLS
QATQLAKEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELSDVDVEQALPAGFDASGS
VEEFMARLAQADAAFAERVAQAKAEGKVLRYVAQIVDGQCQVRIVAVDENDPMFKVKEGE
NALAFYSRYYQPIPLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV
NT seq
2478 nt
NT seq
+upstream
nt +downstream
nt
atgcatttggaggaagggatgcgagtattaaagtttggaggttcatcgctggcggatccg
gagcgttttctacgcgctgccgatatcatcgcgaataacgcacagcaggaagaggtggcc
gttgtcctctctgctccgggaaaaaccaccaataaattggtggcagtgattgaaagtgct
ttacgtcagggagaggtggaagcgcaaatcgtagagctagagagctcattctatgccttg
cttgatggcattaaagcgcagctcccgaatttggatgacagtgcttatcaacagcaagtg
cactcttccatgactcagttacgccagtttgtgcacggcattacgttgctcggtatgtgt
ccagacaatgtgaatgcacgcattatcagtaaaggtgaacgcgtttccattcaattgatg
aaagcggtgatggaagccaaaggtctgccagcgaatttggttgatcccgttaaatacctg
cttgccaaaggggatcatcttgaagctatggtcgatgtggaaatttcgactcagcgtttc
agacaagcaccattgccacaacagcacgtcaatatcatgccgggctttactgcgggtaat
gcacagggtgagttggtctgtttagggcgtaacggttcggattactcagccgcggtactg
gctgcctgtttacgtgcggattgttgtgaaatctggacggatgtggatggagtttataac
tgcgatccgcgtttggtcgatgatgcgcgccttcttaaatcccttagctatcaagaggcg
atggagctttcttacttcggagcatctgtgttgcatccgaagaccattgcaccgattgct
caatttcaaatcccttgtttgatcaaaaacagcttcaatccacaaggtgcgggcaccttg
attggccaagacactggcgaagataaactcgcgatcaaaggcattaccactctgagcaat
ctcactatggtcaacgtttctggtccaggaatgaaaggcatggtggggatggcgagccgc
gtgtttggcgcgatgtcagcggccgatgtgtcgatcgtgcttatcactcaatcttcttcg
gaatacagcatcagtttctgtatcgaagcacaacataaagctttggcacagcaagcgctg
gcggatgcatttgaactggaactcaaagatggcctgcttgagccggttgagtttgtcgat
aacgtcgccatcatcacgctggttggtgatggtatgcgcacctctcgcggtgtcgcgtcg
caatttttctcatctctggccgaagtacacgtcaacgtgattgcaattgcccaaggctct
tctgagcgtgcgatttcagcggtgatccccgatgataagatttcagaagcgatcaaggct
tgccacgaaaacctcttcaactctaaacactttttagatgtgtttgtggtcggtgttggt
ggcgtgggtggtgagttggtggatcaaattcagcgtcaacaagccaagcttgcggaaaaa
ggcatcatgatgcgcgtttgtggcctcgctaacagtaaaggcatgctgcttgatagccaa
ggcttgccgttggagcagtggcgcgatcgtatggtcaatgcggatcaagcgttcagttta
gagaatctggtggctttggtgcagcgtaatcacatcattaacccagtattggtggattgc
acgtccagtgatgagattgctaaccagtatgcggatttcctcgccgcaggtttccatgtg
gtgaccccgaacaagaaagccaataccgctagcatgagttattaccatcagctacgtaat
gtggcgcgtcactcgcgtcgtaaactgatgtatgaaactacagttggcgcgggtctgccc
gttatcgaaaacttgcaaaacctaattgcagcaggggatgagctggaaaaattcagcggt
attctctcaggttctctctcctttatctttggtaaattggatgaaggcatgaccttgagc
caagcaacgcagcttgctaaagagaaaggctttacagagccagatccgcgcgatgacctc
tctggtatggatgtggcgcgtaagttactgattttggcgcgtgaagcgggttacgagttg
gagctgagcgatgtggatgttgaacaagctctgcccgctggctttgatgcttcaggcagt
gttgaggagttcatggctcgtttagcgcaagccgatgccgcgtttgctgagcgagtagcg
caagccaaagccgaaggtaaagtgctgcgctatgtggcgcaaatcgtcgatggccagtgc
caagtgcggattgtcgcggttgatgaaaacgatcctatgttcaaagtcaaagaaggtgaa
aacgcgctggctttctacagccgttactatcagccaatcccattggtattacgtggttac
ggcgcgggttctgaagtgactgctgcaggcgtgttctcagatgtgatgcgtacactcggt
tggaaattaggggtttaa
DBGET
integrated database retrieval system
