Vibrio cholerae O1 O395: VC395_2606
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Entry
VC395_2606 CDS
T02099
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
vcr
Vibrio cholerae O1 O395
Pathway
vcr00290
Valine, leucine and isoleucine biosynthesis
vcr00660
C5-Branched dibasic acid metabolism
vcr01100
Metabolic pathways
vcr01110
Biosynthesis of secondary metabolites
vcr01210
2-Oxocarboxylic acid metabolism
vcr01230
Biosynthesis of amino acids
Module
vcr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
vcr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
VC395_2606 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
VC395_2606 (leuC)
Enzymes [BR:
vcr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
VC395_2606 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
VC395_2606 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ACP10593
UniProt:
A5F5E2
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All DBs
Position
I:2757582..2758985
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AA seq
467 aa
AA seq
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MSKAKTLYEKIYDAHVVVAAPGETPILYIDRHLVHEVTSPQAFDGLREKGRPVRQVSKTF
ATMDHNVSTTTKDINASGEMARIQMQTLSKNCEEFGVTLYDINHKYQGIVHVMGPELGIT
LPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEVRGKVAPGI
TAKDIVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIELGAKAGLIAPDAT
TFNYIKGRKFAPQGSDWDAAVDYWQTLKTDEDAQFDAVVTLEASEIKPQVTWGTNPGQVI
AVDEPIPSPSQFADPVERSSAEKALAYMGLEAGKMLSDYKVDKVFVGSCTNSRIEDMRAA
AAVAKGKKVASHVQALIVPGSEQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRL
GPGERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRQF
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgtcaaaagccaaaactctttacgaaaaaatttacgatgcccatgtggtggtggccgca
ccgggtgaaacgccgattctgtacatcgatcgtcatctagtccatgaagtgacctctcca
caagcctttgatggcttgcgtgaaaaaggtcgcccggtacgccaagttagcaaaactttt
gcgaccatggatcacaacgtctccaccactactaaagacatcaatgcctcaggtgaaatg
gcgcgcatccagatgcaaacgctttccaaaaactgcgaagagtttggcgtcacgctgtac
gacattaaccacaagtaccaaggcattgtgcatgtgatgggacctgagcttggtattacc
ctccccggcatgacgattgtatgtggtgattcacacaccgcaactcacggtgcattcggc
tcgcttgcctttgggataggcacctcagaagtagaacacgtactggctacccaaacccta
aagcaaggccgcgctaagacgatgaaaatcgaagtgcggggcaaagtggctcccggcatc
accgctaaagacatcgtactggcgatcattggtaaaacaactgccgctggcggtacaggc
tatgtcgtggaattttgtggagaagcgattcgcgatctctccatggaaggtcgcatgacc
gtgtgtaacatggcgattgaacttggtgcgaaagcaggcttgattgcccctgatgcaact
acattcaactacatcaaaggccgcaagtttgccccacaaggcagtgattgggatgctgct
gtcgactattggcaaacattaaaaaccgatgaggatgcacagttcgatgccgtcgtgacg
cttgaagccagtgaaatcaaaccgcaagtgacttggggtaccaacccaggccaagtgatt
gccgttgatgagccaatcccatcacctagccagtttgccgatcctgttgaacgcagctca
gcagaaaaagctctggcttacatgggacttgaagccggcaaaatgctctccgattataag
gtcgataaagtgttcgtcggttcatgcaccaactcgcgcatcgaagatatgcgcgctgcg
gcagcggtagccaaagggaaaaaagtcgcctctcatgtccaagcattgatcgtgcccgga
tccgaacaagtgaaagcgcaagccgaagcggaaggcttagataagatctttattgaagca
ggatttgaatggcgcttaccgggttgctcaatgtgtttagccatgaacaatgaccgctta
gggccaggagaacgctgcgcgtctacctcaaaccgcaactttgagggacgtcagggacgt
gatggtcgcactcatttagttagcccagcaatggcagccgctgcagcgattgctggtcac
ttcgtcgatattcgtcagttttaa
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