Vespa crabro (European hornet): 124421775
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Entry
124421775 CDS
T09462
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
vcrb
Vespa crabro (European hornet)
Pathway
vcrb00270
Cysteine and methionine metabolism
vcrb00480
Glutathione metabolism
vcrb01100
Metabolic pathways
vcrb01240
Biosynthesis of cofactors
Module
vcrb_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
vcrb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
124421775
09106 Metabolism of other amino acids
00480 Glutathione metabolism
124421775
Enzymes [BR:
vcrb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
124421775
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
124421775
NCBI-ProteinID:
XP_046813334
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Position
1:22387343..22391514
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AA seq
638 aa
AA seq
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MGLLSEGSPLSWEETKKLSDHVRKHGIIQFINIYKKLRDRQGDVLKWGDEVEYLLVKFDD
VAKTAKLSLRAEEILKVLNEKELKDPSNVKSLWRPEYGAYMIEGTPGKPYGGLLAHFNVV
EANMRYRRQEATKLLKHGEVLMSLTNFPRLGASDFTDPPVVPTPNDGASRSLFFPDEAIY
PGHPRFKTLTKNIRERRGEKVAINIPIYKDINVPSPFKEDLISQGDDGSSGKAAKIDHVY
MDAMGFGMGCCCLQLTFQACNIDEGRTLYDQLTPLCPIMLALTAASPFYRGYVTDVDCRW
NVISCSVDCRTQEERGLKPLEENQFRIHKSRYDSIDSYLSEQGDKYNDVPLIYDTEIYKQ
LLDNGIDRLLAQHIAHLFIRDSVSLFSEKIHQNDLEDTDHFENIQSTNWQTMRFKPPPPY
SSIGWRVEFRPCEVQITDFENAAIVCFIVLLTRVILSYKLNLLIPISKVDQNMAKAQKRN
AVKNEKFWFRKDITSNTVKKDNTEEEYDEFTINEIINGKNGVFPGLIPLVNSYLANMDVD
ADTHCTVQRYMKLIQRRASGELLTTAAWLRKEVISHPEYKHDSVITQRINYDLMKKIDSI
VSNEVSCPELLGPCIASKTTETIPPAVAKAEKCRDMDC
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgggacttttatccgaaggaagtccacttagttgggaagaaacgaaaaaattgtcggat
catgtgcgaaagcatgggatcatacaatttattaatatatataagaaactcagagataga
caaggtgatgtactcaagtggggtgatgaggtagaatacttattagtaaaatttgatgat
gtagcaaaaacagcaaaacttagcttaagagccgaagaaatattaaaagttttaaatgaa
aaagagctgaaagatccgtcaaatgttaaatcgttatggcgaccagaatatggtgcatat
atgattgaagggacaccagggaaaccatatggaggtttattagcacattttaatgttgta
gaagcaaacatgcgttatcgtagacaggaagcaacaaaattattgaaacatggagaagta
ctaatgtcactgaccaattttccaaggctaggagcatcagattttacagatcctccggtt
gtacctactccaaatgatggagcctccagaagcttgttttttccagatgaagcaatatac
ccaggacacccacgttttaaaacattgacaaaaaatattagagaacgtcgtggagagaaa
gttgctataaacattcctatttacaaagatataaatgttccttctccgtttaaagaagat
ctaataagtcaaggagacgatggatccagtggtaaagctgcgaaaatagatcatgtttat
atggatgctatgggttttggaatgggatgttgttgtttacaacttacttttcaagcttgt
aatatagatgaaggtcgaacattgtatgatcaacttacaccattgtgtccaatcatgttg
gctttaactgctgctagcccattttatcgtggatatgtgacagatgttgattgtcgatgg
aatgtaatttcctgctcagtcgactgtagaacgcaagaagaacgtggattgaaacctttg
gaagaaaatcaattcagaattcacaaatctagatatgattccattgattcatacctcagt
gaacaaggagataaatataatgatgttccactgatatatgacactgaaatatacaagcaa
ttactagataatggaattgatagattacttgctcaacatatagctcatttatttatcaga
gattctgtatctttgttttctgaaaaaatacatcagaatgatttggaagataccgatcat
tttgaaaatattcaatcgaccaattggcaaacaatgcgattcaaaccaccacctccatat
tcttctataggatggcgagttgaatttcggccatgtgaagtacaaattacagatttcgaa
aatgcagctattgtttgttttattgtacttctgacaagagttatactcagttacaaatta
aatttacttataccaattagtaaggttgatcaaaacatggctaaagcacaaaaaagaaat
gctgttaaaaatgaaaagttttggtttcgtaaagatattacatcaaatactgtaaagaaa
gataatacagaagaggagtatgatgaatttaccattaatgaaattattaatggcaagaat
ggcgtttttcctggattaataccattggttaattcttatcttgctaatatggatgtggat
gcagatacacattgtacagtacaaagatacatgaaattaattcaaagacgtgcatctggt
gaactcctaacaacagctgcatggcttagaaaagaagtaatctcacatccagaatacaaa
catgattctgtcataacacaacgtatcaactacgacttaatgaaaaagatagatagtatc
gtatccaatgaagtttcttgcccagaattacttggaccatgcatagcatctaaaacaacc
gaaacaataccaccagctgttgctaaagcagaaaagtgccgagacatggattgttaa
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