Vibrio cholerae O1 El Tor MS6: MS6_1222 Help Entry MS6_1222          CDS       T03666                                  Name (GenBank) RTX toxin RtxA   KO K10953   RTX toxin RtxA Organism vcs  Vibrio cholerae O1 El Tor MS6 Module vcs_M00850   Vibrio cholerae pathogenicity signature, cholera toxins Brite KEGG Orthology (KO) [BR:vcs00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:vcs02042]     MS6_1222 Bacterial toxins [BR:vcs02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    MS6_1222 SSDB OrthologParalogGFIT Motif Pfam:  ACD RtxA IcsB_M Peptidase_C80 MLD RtxA_C Abhydrolase_1 Hydrolase_4 Abhydrolase_6 Abhydrolase_3 DUF1057 Thioesterase Abhydrolase_11 Lnb_N Motif Other DBs NCBI-ProteinID:  BAP02877 LinkDB All DBs Position 1:1399533..1413170 Genome browser AA seq 4545 aa AA seqDB search MGKPFWRSVEYFFTGNYSADDGNNNIVAIGFGGQIHAYGGDDHVTVGSIGATVYTGSGND TVVGGSAYLKVEDSTGHLIVKGAAGYADINKSGDGNVSFAGAAGGVSIDHLGNHGDVSYG GAAAYNGITRKGLSGNVTFAGAGGYNALWHETNQGNLSFTGAGAGNKLDRTWSNRYQGSH GDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGDITLQGAGASNRIERTHQA EDVYTQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNTIIRKGSGNDFAKEGMTNAK ADEIVLTKAVMSGSWIGQDHHVTAVKSASEPNTYLFAFADSTYTKINKVQLRNDPQTGEL KYYSTAWYKEVNHLSNLANQDISDNGGFTAVNINGAYTLSDLKVEHQQSVTVHAVEKSLT EYEWVTYANGAVIDAKEVSLSDAKMGGHAIYADGTKVDVKAVKSNRQPNTYIYAKVLGPY TKIVVVELANDPETGALKYQARSWYKEGDHTANIANQDISSATGYNPMGKGGYSLSDLHY SVNAVRSTSETVADIEEYTDQTLFKPANDSGESSGDVRFNGAGGGNVIKSNVTRGNVHFN GGGIANVILHSSQFGNTEFNGGGAANVIVKSGEEGDLTFRGAGLANVLVHQSEQGKMDVY AGGAVNVLVRLGDGQYLAHLLAYGNISVQKGSGDSRVVMLGGYNTHTQIGSGNGLWLAAG GFNVMTQVGKGDVAAVLAGGANVLTKMGEGELTSGMLGGANVITHISNDDQLSNTTAVAL GGANILTKKGKGNTLAVMGGGANVLTHVGDGTTTGVMVGGANILTKVGNGDTTGILLGVG NVLTHVGDGQTLGVMGAAGNIFTKVGDGTSIAVMIGAGNIFTHVGEGNAWALMGGLGNVF TKVGNGDALALMVAEANVFTHIGDGMSVALMLAKGNVATKVGNGTTLAAMVGNVNIFTHI GHGSTFAAMIGQANIMTKVGNDLTAALMVGKANIMTHVGDGTSLGLFAGEVNVMTKVGNG TTLAAMFGKANIMTHVGDGLTGVLALGEANIVTKLGDDFMGVVAAAKANVVTHVGDATTA AVLAGKGNILTKVGEGTTVGLLISDVGNVMTHVGDGTTIGIAKGKANLITKVGDGLGVNV TWGQANVFTQVGDGDRYNFAKGEANLITKVGDGQEVSVVQGEANIITHVGNGDDYTGAWG KANVITKVGHGQNVVLAKGEANIVTQVGDGDSFNALWSKGNIVTKVGDGMQVTAAKGQAN ITTTVGNGLNVTAAYGDANINTKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANI HVGDGLNINASYAQNNVAIKVGNGDFYSLAVASSNTSSNKLSALFDNIKQTVLGVGGSQA INYLVQGDEASSSGTHKGRGAIATPEITKLDGFQMDAIKEVSSDLGDSLTGSVTKVDTPD LNKMQHALNVDDSSVQAPNLIVNGDFELGEHGWQSTHGVEASYAGSVYGVEGEGHGARVT ELDTYTNTSLYQDLANLAQGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDESAW QQKNLKLTAQAGSNRIEFKGTGHNDGLGYILDNVVATSESSQQANAIREHATQNPAAQNA LSDKERAEADRQRLEQEKQKQLDAVAGSQSQLESTDQQALENNGQAQRDAVKEESEAVTA ELAKLAQGLDVLDGQATHTGESGDQWRNDFAGGLLDGVQSQLDDAKQLANDKIAAAKQTL SDNNSKVKESVAKSEAGVAQGEQNRAGVEQDIADAQADAEKRKADALAKGKDAQQAESDA HHAVNNAQSRGDRDVQLAENKANQAQADAQGAKQNEGDRPDRQGVTGSGLSGNAHSVEGA GETDSHVNTDSQTNADGRFSEGLTEQEQEALEGATNAVNRLQINAGIRAKNSVSSMTSMF SETNSKSIVVPTKVSPEPERQEVTRRDVRISGVNLESLSAVQGSQPTGQLASKSVPGFKS HFASTSIGIENELSGLVVVLPKNSAQTFGYVHDSQGNPLFMLTKDMNQGGYSNPVGINDI QGVNNWQTHTIELVTYPSEISDTAAVESRKEAMLWLAKEFTDHINQSNHQSLPHLVSDDG RFTLVISNSKHLIAAGNGTSIDAQGKTIGMTPSGQQATMAISAKEFGTSSSPEVRLLESA PWYQAGLRDEFLANAKNTTLDDPATAQNVYAYLTSVYSKTADLAKEYGIYINDWDPASEG FSPNAQGLTDPKVKNAWSILPRTKPVRMLELLSAEDSRYVRQQIAEKLKGTYSESLAKNV FEYFQYGGEVAGHGINNATTRSVQQPEPAILFEFRSVPSALSDFVPKTASTVKVDVKALD HFDSASRKAIITEVNALVSGSEDFDAWYQEYRASKGQPPVKNPKSSASANHKAEWLMTQH AEQWAKITAPYTDNHETLTSTKLASNDKEELHALGETSNLENNKQQENVASIINTMLNDM LPFYALRTERNLLVQEGDEGFEVRAWPGTEDKSKTIILEDPEDAAQHKAIERFILANFDN FEQMPDELFLVDNKVISHHEGRTHVLAQKVDGAWQYNATVELMSVTELLDAANVTGKIRG ESYQQVIDALTDYHASITEHADYEPESVEKLLNLRKKIEGYVLGHPDSGRVEAMNSLLNQ VNTRLDEVSLLSVAEQTIQAQNSFSRLYDQLEAANLKESKHLYLDQNGDFVTKGKGNLAN IDLLGSREAVLEKVKLTVSNEYGQTVADTIFAGLSAKDLAKDGKGVDIAGLNKVHQAIEQ HLSPVSATLYIWKPSDHSALGHAALQIGQGRTQLEGQAAADFNQQNYVSWWPLGSKSSNI SNILNVATKDQPDLKLRWSDFSQPAHQNDTLEHDVASEENDGFGLHDGDIKLKRFIEKLN AAKGIDASFKEASEGYASVLLGNPDMLETTGIPAHVFQPFVEQWNDTSYDMMDVAHRFAQ ELRLQAQRSDDPELLEKRIGNVIRQFAERALEEIETFKASQADQGRVFRINLEGLDVAAM QAEWHRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWLPKFGVWTPTELFNFGQ ALQEAQLEIAAKKQSHQVTDVLDALSGNEKPKENVAIENDGTPPRDKESLSPLTRFLNNE LYGDKEARRKIGEITQTLLDHAVEKGESQKITLQGEAGRLTGYYHQGTAPSEGETSSPSG KVVLFLHGSGSSAEEQASAIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTMFN YLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITAHEV ANPAGIVGAIAKAVNGQFSVEKNLEGLPKETSILLLTDNEGLGNEGEKLRTKLTASGYNV TGEQTFYGHEASNRLMSQYADQIVSGLSSSASVDEDLDQQGLDTTSTKDQGISNKNDHLQ VVDSKEALADGKILHNQNVNSWGPITVTPTTDGGETRFDGQIIVQMENDPVVAKAAANLA GKHAESSVVVQLDSDGNYRVVYGDPSKLDGKLRWQLVGHGRDHSETNNTRLSGYSADELA VKLAKFQQSFNQAENINNKPDHISIVGCSLVSDDKQKGFGHQFINAMDANGLRVDVSVRS SELAVDEAGRKHTKDANGDWVQKAENNKVSLSWDAQGEVVAKDERIRNGIAEGDIDLSRI GVNNVDEPARGAIGDNNDVFDAPEKRKPETEVIANSSSSNQFSYSGNIQVNVGEGEFTAV NWGTSNVGIKVGTGGFKSLAFGDNNVMVHIGDGESKHSVDIGGYQALEGAQMFLGNRNVS FNFGHSNDLILMMDKSIPTPPLVNPFDGAARISGVLQGIATSGEGEDWLAAQEQQWTLSG AKKFVKDMSGLDQSSSVDYTTLVELDSQNERDSRGLKHDAEATLNKQYNQWLSGNGNSGT SQLSRADKLRQANEKLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMT QQFTATGQAKTTFTYTPQDLPRQLKNKLLGQLAGVGAETTLADIFGVDYTASGQIVSRNG QAVDGVAILKEMLEVIGEFSGDQLQAFVDPAKLLDSLKAGIDMGADGIKSFAETHGLKEK APEEEKDNSSVSVNGANVNSAQGATVADGNTETAETQDRAFGFNSLNLPNLFATIFSQDK QKEMKSLVENLKQNLTADLLNMKEKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDL GAYLGDNNNFWGGRGDDVFYATGKSNIFTGGEGNDMGVLMGRENMMFGGDGNDTAVVAGR INHVFLGAGDDQSFVFGEGGEIDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVEL GAGNDFANIFGNYNRINAGAGNDVVKLMGYHAVLNGGDGDDHLIATAISKFSQFNGGEGR DLMVLGGYQNTFKGGTDVDSFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDL KLSILRDPSNDSDQSKFEHIGSVTFSDYFNGNRAQVVIGMSEKDLSGEREYTMLSDSAID ALVQAMSGFEPQAGDNGFIDSLESKSQAAISMAWSDVVHKKGLMV NT seq 13638 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaccattttggagaagtgttgaatacttcttcacaggaaactattccgccgac gatggaaacaacaacattgtagccattggttttgggggacaaattcatgcctacggcggt gacgaccacgtcactgttggatcgattggtgcaacggtgtacaccggtagcggcaacgat acggtcgtgggcggctctgcctatctcaaagtggaagattccactggccacctaattgta aaaggcgcggctgggtatgcagacattaataaaagtggcgatggcaatgtgtcattcgct ggtgccgccggtggtgtgtcgattgaccacttaggcaatcatggtgatgtcagttacggc ggtgccgcggcttataatggcattacccgtaaagggttgagcggcaatgtcacctttgca ggcgcggggggatacaatgccctctggcatgaaaccaaccaagggaacctgtcttttaca ggagcaggcgcaggtaataaattagaccgtacttggtctaaccgttatcaaggctcgcat ggcgatgtgacctttgatggtgctggtgccgcgaacagcatcagttcacgcgttgagaca ggtaacatcaccttccgtggcgcaggtgcggataaccatttagtccgtaaaggcaaagtg ggcgatattactctgcaaggtgctggggcttcaaaccgcattgagcggacacatcaggcc gaagatgtctacacgcaaacccgcggcaatattcgttttgaaggtgtgggtggttacaac agtctttactctgatgtggctcatggtgacattcatttctcgggtggcggtgcgtacaac accattattcgtaaaggttctggaaatgactttgcgaaagaaggcatgaccaatgctaag gctgatgagattgtattaactaaggccgtgatgagtggctcatggatagggcaagatcat catgtcacagcggtgaaatcggctagcgagcctaatacatatctttttgctttcgcagac tctacgtataccaaaattaacaaagtacagttacgcaatgatcctcaaactggagaactg aaatattactctacggcttggtataaagaggttaaccatctaagcaacttagcgaatcaa gacatttccgacaacggtggtttcacagccgttaatatcaatggcgcctacacgctatct gacctcaaagttgaacatcagcaatccgtcaccgttcatgcggttgaaaaaagcctgact gaatatgagtgggtgacttacgccaatggtgcggtgattgatgcgaaagaggtgtcattg tcggatgccaaaatgggcggtcatgcgatttatgctgatggcactaaggtggatgtcaaa gcggtaaaatccaaccgccaacccaacacttacatttatgccaaagtgcttgggccttac acaaaaattgtggtggtggaactggcaaacgatcccgaaaccggggcactgaaatatcaa gctcgctcttggtataaagaaggtgatcacacggccaatatagccaaccaagatatttca tctgcaactgggtataacccaatgggcaaaggtggctactcgctcagtgacttgcactac agcgtaaacgccgttagaagtaccagcgaaaccgtagcggatatcgaagaatacacagat caaaccttgtttaaacccgcaaacgatagcggtgaaagctcaggtgatgttcgtttcaac ggtgccggtggcggtaacgtcatcaaatcaaacgtgacgcgtggtaatgtgcatttcaac ggtggcggtattgccaacgtgattttgcatagctcccaatttggtaataccgaatttaac ggtggtggtgcggcgaacgtcattgtcaaaagtggcgaagaaggggatctcaccttccgc ggcgcaggtttggcgaacgtcttggtacaccaaagcgaacaaggcaagatggatgtgtac gcgggcggtgcggtaaacgtgttggttcgccttggcgatgggcaatatctcgcgcattta ctggcttacggtaacatttcagtccaaaaaggcagtggtgatagtcgcgtcgtgatgctc ggtggctacaacacccatacccaaatcggctctggcaacggattatggttggccgcgggc ggtttcaacgtgatgacgcaagtcggcaaaggtgatgttgctgcggtactcgctggcggt gcaaacgtactgaccaaaatgggtgagggtgaactcacgtcgggtatgctgggtggcgcg aacgtaataacccacatcagcaatgatgatcaattatcgaataccacggctgtggcactt ggcggtgcaaatattctcaccaaaaaaggcaaagggaatacccttgcggtgatgggtggt ggcgcaaacgtgcttacccatgttggtgatggcaccacaacgggtgtcatggtcggcggt gcgaacattctcaccaaagtaggtaacggcgacacgaccggcattctgcttggcgttggc aacgtgctgacgcatgtgggtgatggccaaacccttggcgtaatgggcgcggcgggtaac atcttcaccaaagtgggtgatggaacctctattgcggtcatgattggtgctggcaacatt tttacccatgtgggggaagggaatgcttgggcgctgatgggcggcttgggtaacgtcttt accaaagtaggcaacggtgatgctctcgcgttaatggtagcagaagccaacgtcttcact cacattggtgatggcatgtcggtggcactgatgttagccaaaggcaacgttgcgacaaaa gtgggtaatggaaccacactcgcggcgatggtggggaacgtcaacatctttacccatatt ggtcatggcagcacgtttgcggcgatgatcggccaagccaatatcatgaccaaagtgggc aatgatctcacggcggcgctgatggtcggcaaagcgaacatcatgacccatgttggcgat ggtaccagcctagggctgtttgctggcgaagtgaacgtgatgactaaggttggtaacggc accacgttagcggcgatgttcggtaaagcgaacatcatgacccatgtcggtgatggctta accggtgtactcgcactgggtgaagccaatatcgtgaccaaattgggtgatgatttcatg ggggtggtggccgcggctaaagccaacgtcgtgactcatgttggtgatgctaccaccgca gccgtattggcgggtaaaggcaatatcctcaccaaggtgggtgaaggcaccacggtaggg ttgttgatttccgatgtcggcaacgtgatgacccacgttggtgacggcaccaccattggt attgccaaaggtaaggccaacctcattaccaaagtcggtgatggtttaggtgttaatgtc acttgggggcaagccaacgtgtttacccaagtgggcgacggtgatcgctataactttgcc aaaggtgaagccaacctcatcaccaaagtgggtgatggccaagaagtctccgtggtgcaa ggtgaagccaacatcattactcatgtgggcaatggcgacgactacactggcgcttggggt aaagcgaacgtcattactaaagtcggtcatggccaaaacgtggtactggcaaaaggtgaa gccaacattgttactcaagtgggtgatggcgacagctttaacgcactttggagcaaaggc aacatagttaccaaagtgggcgatggtatgcaggtgacggcggcaaaaggccaagccaat atcaccaccaccgtgggtaacggtttaaatgtcactgctgcctacggcgatgccaatatc aacaccaaggtcggtgatggggtatccgtcaacgtcgcttggggcaaatataacatcaac acgaaagtgggtgatgggctcaatgtcgctgtgatgaagggcaaagctaacgccaatatt cacgttggggacggcctcaacatcaatgcctcctacgcacaaaacaacgtcgccatcaaa gtcggtaacggcgatttctatagtttagcggtggcatcgagcaataccagcagcaacaag ctctctgccttgtttgataacatcaaacaaaccgtactcggtgtcggtggcagccaagcc atcaactacttagtgcaaggcgatgaagcctcctcatccggcacgcataaaggtcgtggt gcgattgctacacctgaaatcaccaaactggatggtttccaaatggatgccattaaggaa gtcagttctgacctcggtgatagtctcacgggcagcgtgactaaggttgatactcctgat ctcaacaagatgcagcatgcgctcaatgttgatgattcttccgttcaagctccgaatctg attgtgaatggggattttgagctgggcgaacatggctggcaatctactcatggggttgaa gcctcttatgcaggcagtgtgtatggcgtagagggtgaaggtcacggcgcacgtgtgacc gagctcgatacttataccaacaccagtctctatcaagatctggctaatctagcgcaaggt gaagttattgcggtgagctttgattttgcaaaacgcgcgggcctttctaataacgaaggc atcgaagttctttggaacggtgaagtggtattctcatcgtcgggtgacgagtctgcttgg cagcaaaaaaacttaaagctgaccgcgcaggctggcagtaaccgtatcgaattcaaaggc acaggccacaatgatggactgggctacatcctagataatgtggtggcgacctcagagtca tcgcaacaagccaatgcaatccgtgagcacgcaacgcaaaacccagcagcgcagaatgct ctatccgataaagagcgtgcagaagcggatcgccaacgtcttgaacaagaaaagcagaaa cagcttgatgctgtcgcagggtcacaaagtcagttggagtcgaccgaccaacaagcgcta gaaaataatggtcaagctcaacgtgatgcggtgaaagaagagtcggaagccgtgaccgcc gagttggcaaaactggcgcaaggtctcgatgtgcttgatggccaagcaacgcatactggc gagtccggcgaccaatggcgcaatgattttgccggtggtctgctcgatggcgttcaaagc cagctcgacgatgccaagcaactcgcgaatgacaagattgctgcagcgaagcagaccctg tctgacaataacagcaaagtcaaagaatccgttgcgaaatctgaagcgggtgtggcacaa ggcgagcaaaatcgagcgggagtagagcaagacattgctgatgctcaagccgatgctgaa aaacgtaaagccgatgctttagcaaaaggtaaggatgcacaacaagcggaatctgatgca catcatgcggtaaataatgctcaatcacgcggcgatcgtgatgtgcaattggcggaaaac aaagccaaccaagcacaagccgatgctcaaggtgctaaacaaaacgaaggtgatcgtcct gatcgtcaaggcgtgactggtagtggcctttcgggtaatgctcatagtgtggaaggcgct ggcgaaacagacagtcatgtcaacaccgacagccaaaccaacgccgatggccgattcagt gaaggtttaaccgaacaagagcaagaagcgctagaaggtgcgaccaacgcagtgaaccgt ttgcaaattaacgcaggtattcgagcgaaaaacagcgttagcagtatgacttctatgttc tctgaaacaaatagcaagagcattgttgttcctaccaaagtctcgcctgaaccagagcgc caagaagtgactcgtagagacgtccgtatctcaggggtgaacctcgaaagtctaagtgcg gtacagggaagtcaaccaacgggtcaactggcttcgaaaagtgtccccggatttaaaagc catttcgcatcgacatccattggtatagaaaatgagttatccggtctggtggtggtttta ccgaaaaactcagcgcagacttttggctatgtgcatgattcacaaggtaacccattgttc atgctaaccaaggatatgaatcaaggtggttatagcaacccagtgggtatcaatgatatt caaggggtgaacaactggcagacgcatacgattgaactggttacatatcctagtgaaatc agtgatacagcagcggttgaaagtcgtaaagaggcaatgctatggcttgcgaaagagttt accgatcatatcaatcagtctaaccaccaaagcttacctcatttagtgagtgatgacggt cgtttcactctggttatatcgaactctaagcatcttattgcggcgggtaacggaacctct attgatgcacaaggcaagaccataggaatgacccctagtggccaacaagcaacaatggcg atcagtgcgaaagaatttggtacaagctcgtcgccggaagtcagactgcttgaatctgcg ccttggtatcaagcagggttgagagatgagtttttagcaaacgcgaaaaacaccacgttg gatgatcccgctacagcacaaaatgtgtatgcctatctcacgtctgtctattcaaaaaca gcagatttggccaaagagtatgggatctacatcaatgattgggatcctgcctctgaaggt ttttcaccgaatgctcaagggttaacggatccgaaagtcaaaaatgcttggagcatattg ccaagaactaaacccgttagaatgctggaacttctgagtgcggaagactcacgctacgta aggcaacaaattgcggaaaagctgaaaggcacctattcagaaagccttgctaagaacgtg tttgaatacttccaatatggtggagaagtcgctggacatggaatcaataatgcgacgaca agaagtgtgcaacagcctgaaccagcgatcttatttgagtttcgcagtgtaccgagtgca ttaagtgactttgtacccaaaacagcgtcaacggtgaaagtggatgttaaggcactcgat cattttgactcggcaagccgtaaagccatcattactgaagtaaatgctttggttagcggt agtgaggatttcgatgcttggtatcaggagtatcgagcaagcaaaggacagccgccagtc aaaaatcctaagtccagtgcatccgccaatcacaaagctgaatggttgatgacgcagcat gctgaacaatgggcgaaaattaccgctccttatactgataaccatgagacgctcacatct accaagcttgcttctaacgataaagaagaattacacgctttaggtgaaacgtcgaatcta gagaataacaagcagcaagaaaacgtcgcttccataattaacaccatgttaaatgacatg ctgccattctatgcacttcgtaccgaacgaaatctactggtacaagaaggagatgaaggc ttcgaagtgcgtgcttggccaggaaccgaagacaagagtaaaaccattattcttgaggat cctgaagacgcggctcagcacaaagccatcgaacgcttcattctggccaacttcgataat ttcgaacaaatgccagacgagctcttcttggtggataacaaagtgatttcacaccatgaa ggtcgtacacatgtgttggcgcaaaaagtcgatggtgcatggcaatacaacgccacagtc gagctgatgtcagtcactgaactactggatgcggcgaatgtaacgggtaagatccgcggt gaaagctatcagcaagtgatcgacgcattgactgattaccacgccagcatcactgagcac gcagattatgaaccggagtccgtggaaaaactgctcaacttgcgtaaaaaaattgaaggt tatgtactcggacacccagactcaggccgtgttgaagcgatgaattcactgttaaatcag gtgaatacgcgtttagatgaagtttcactgctgtcagttgctgagcaaactatccaagcg caaaacagtttcagccgactatatgaccagctagaagccgctaacttgaaagagagtaag cacctttatctggatcaaaatggtgactttgttaccaaaggcaaaggtaatcttgccaat atcgatctgctaggtagccgcgaagctgtgcttgaaaaagtgaagttaacagtaagtaac gagtacggtcaaaccgttgcggatacaatttttgctggattatcagccaaagatcttgcc aaagacggtaaaggggttgatatcgcgggtttgaataaagtacatcaagcgattgaacag catctgtcacctgtcagcgccacgttgtacatttggaaaccgagtgatcatagcgcgcta ggtcatgccgcattgcaaataggccaaggtcgcacgcaacttgaaggtcaagctgcagct gattttaaccagcaaaattacgtaagctggtggccactaggcagcaagtcatccaatatc agcaatatcttgaatgtggccacaaaagaccaacctgatcttaagctgcgctggagcgac ttcagtcaacctgcacatcaaaatgacacgcttgagcatgatgttgcttcggaagaaaac gatggctttggtttgcatgatggcgacattaagctgaaacgctttatcgagaagctcaat gccgcgaaaggaattgacgcttcatttaaagaggcttctgaaggttacgcgagcgtacta ctgggtaacccagatatgctcgaaacgacaggtattcctgcacatgttttccaaccattt gtcgaacaatggaatgacaccagttatgacatgatggacgtggcacaccgttttgcgcaa gagctcagactacaggctcaaagaagtgacgatcccgaactgcttgaaaagcgcatcggc aatgtgattcgccaatttgcagaaagagcactggaagagatcgaaaccttcaaagcaagc caagccgatcaaggtcgagtattccgaattaaccttgaaggcctcgatgtggcggcaatg caagcagaatggcatcgtctaagcaacgatccggatgctcgttatcaattactgaccaaa aactgctccagcacagtggctaaagtgttgaaagccggcggggcggataaactgattggc catacatggctgcctaagtttggtgtttggacgccgaccgagcttttcaactttggtcag gcactgcaggaagctcagctggaaattgccgcgaagaagcaaagtcatcaagtcactgat gtccttgatgccttgtcaggcaatgagaagcctaaagaaaacgtggcgattgaaaatgat ggtacgccaccgcgcgataaagaatctctgagcccattgactcgattcctcaataacgag ttgtatggtgataaagaggctcgccgtaagattggcgaaatcacgcaaaccctacttgat cacgcggtggaaaaaggtgaatcgcagaaaatcactctgcaaggagaagcgggccgtcta acggggtattaccatcagggaacagccccaagcgaaggtgaaacgagctcgccaagcggc aaagtcgtattgttcctgcacggttctggttcttctgctgaagagcaagcgagcgcgatt cgaaatcactaccagaagcaaggtatcgatatgctcgcagtcaacctgcgtggctatggt gaaagcgacggtggaccaagcgaaaaaggcttgtaccaagatgctcgcaccatgttcaac tacctagtgaatgataagggtattgacccaagcaacatcatcattcacggctactcaatg ggcggtccaattgccgcagatttagcacgttatgccgcgcaaaacggccaagcggtgtct ggcttattgcttgaccgtcctatgccaagcatgaccaaagcaatcaccgctcacgaagtg gcgaatccagcgggcattgtgggggctatcgcgaaagcggttaacggccagttctctgta gagaaaaatctcgaaggtttgccaaaagagacatccattctgctgttgaccgataacgaa ggtttgggtaacgaaggtgagaaacttcgtaccaaactcactgcctctggttacaacgtc actggcgagcagacattctatggtcacgaagcaagcaaccgtttgatgagtcaatatgcg gatcaaattgtctccggtttgtccagcagtgcaagtgtagatgaagacctagatcaacaa gggttggataccacatcaaccaaggatcaaggtatctcaaataagaatgatcatctgcaa gtggtggatagtaaagaagcattagcggatggaaaaatactccataatcaaaatgttaat agctggggcccgattacggttacaccaacgacagatggtggtgaaacccgcttcgacggt caaatcatcgttcaaatggaaaacgacccggtagtagcaaaagcggcagccaatttagca ggtaaacatgctgaaagcagtgtggtggtgcagctcgattcagacggcaactatcgcgtg gtgtatggcgatccgtcaaaactggatggaaagctacgttggcagttggtggggcatggt cgcgaccactcagaaactaacaatactcgcttaagtggttacagtgccgatgagttggcc gtgaaattggccaagttccaacagtcgtttaatcaagccgaaaacatcaacaacaaaccg gatcacatcagtattgttggttgttctttggtgagtgacgacaagcaaaaaggctttggt catcagtttattaacgcgatggatgcgaatggtcttcgtgtcgatgtctctgttcgtagt tctgaactggccgtagacgaggcgggacgtaagcataccaaggacgcgaatggcgattgg gttcaaaaggcagaaaacaacaaagtttcgctaagctgggacgcgcaaggtgaagttgtt gccaaggatgaacgtattcgcaatggtattgcggaaggcgacatcgatctctctcgtatt ggtgtcaacaatgtcgatgaacctgctcgtggcgcgatcggtgacaataatgacgtgttt gatgcgccagaaaaacgcaaaccagaaacggaagtgattgccaattctagcagcagtaat caattcagctactcaggtaacattcaagttaacgtgggcgaaggggagtttacggcggtg aactgggggacatcgaatgtgggcattaaagtcggtactggtggctttaaatcgctggcc tttggtgacaataacgttatggttcatatcggtgacggtgaaagcaaacacagtgttgat atcggtggctatcaagcactggaaggtgcgcaaatgttcctcggtaaccgtaatgtgagc tttaatttcggacacagtaatgatctgatcctaatgatggataagtcgatcccaactcca ccactcgtcaatccattcgacggtgccgcacgtatttctggtgtgttgcaaggtattgct acgtctggagagggagaagattggcttgccgctcaagagcagcaatggacactgtctggc gcgaagaagttcgtcaaagatatgtctggtttggatcaaagtagcagtgtggattacacc acattagttgaattggattcacaaaatgaacgtgatagccgtggcctgaagcacgatgca gaagcgacactgaataagcaatacaatcagtggctaagcggtaacggtaatagtggcacg agtcagctcagccgcgctgataagcttcgtcaagccaatgaaaagctagcatttaacttt gccgtaggtggacaaggggcggatattcaagtcacgacgggtaactggaactttatgttc ggcgataacattcagtcgattttggataccaacttaggttcactgtttggtctcatgacg cagcagttcaccgcaacgggacaagcaaaaaccaccttcacttatacgccacaagatttg ccgcgccagctcaagaataagctactcggccagttagctggagtaggggctgaaacgaca ttggcggatatttttggtgtggattacaccgcgtcaggtcaaattgtttcgcgtaatggt caagccgtcgatggagtggcgattctcaaagagatgctggaagtcatcggtgagttcagc ggagatcaactgcaggcttttgtcgacccagctaagttactggatagcttgaaagcgggt atcgacatgggagcggatggcatcaagtcttttgctgaaactcatgggctgaaagagaaa gcgcctgaagaggaaaaggacaattcttcggtttctgttaatggtgcgaacgtgaacagt gcgcaaggtgcgactgtggctgatggcaatactgaaacagcagaaacacaagatcgtgcc tttggctttaactcgcttaacctgcctaacttgtttgcgactattttcagccaagataag cagaaggaaatgaagtcactggtggagaatcttaaacagaatctcaccgccgatctgctg aatatgaaggagaaaacgtttgatttccttcgtaatagtggccatctccaaggagatggt gatatcaacatctccctaggaaactacaacttcaactggggtggtgatggtaaagatctc ggtgcgtatctcggagataacaacaacttctggggtggacgaggcgatgatgtgttctac gcaacaggcaagtcaaacatcttcacgggtggagaaggcaacgacatgggcgttctgatg gggcgtgaaaacatgatgtttggtggtgatggcaacgacacggcagtggttgctggacgc attaaccatgtcttccttggtgctggtgacgaccagtcgtttgtctttggcgaaggtggt gaaattgataccggttcaggccgtgactatgtggtgacttctggcaacttcaaccgtgtg gatacgggagatgatcaagactactccgttacgattggcaacaataaccaagtggaactc ggagcaggtaatgactttgccaatatctttggtaactataaccgtatcaatgccggtgcg ggtaacgatgtggtgaaactgatgggttaccatgccgtgctaaacggtggtgatggagat gatcacctgattgcaacggccatctctaagttcagccagttcaacggtggtgaaggccgt gatctgatggtacttggtggttatcaaaatactttcaaaggtggcacggatgtggacagc tttgtggtgagcggtgatgttatcgacaaccttgtggaagacattcgcagcgaagataac attgtcttcaatggtatcgattggcagaaactgtggttcgagcgcagcgggtatgacctg aaactgtcgattttgcgtgatccgtctaacgacagtgaccaatcgaagtttgagcatatt ggttcggtgacattcagtgattactttaatggtaaccgcgctcaagtggttatcggaatg agtgagaaagacctgtcgggtgaacgtgaatacaccatgttatcggatagtgcgattgac gctctggttcaagcgatgagtggttttgaaccgcaagcgggtgacaatggctttatcgac agcctagagagtaaatctcaagctgcgatcagcatggcgtggtcagacgtggttcacaaa aaaggattgatggtgtaa

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