KEGG   Vibrio cholerae O1 El Tor MS6: MS6_2098
Entry
MS6_2098          CDS       T03666                                 
Name
(GenBank) aspartokinase/homoserine dehydrogenase
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
vcs  Vibrio cholerae O1 El Tor MS6
Pathway
vcs00260  Glycine, serine and threonine metabolism
vcs00261  Monobactam biosynthesis
vcs00270  Cysteine and methionine metabolism
vcs00300  Lysine biosynthesis
vcs01100  Metabolic pathways
vcs01110  Biosynthesis of secondary metabolites
vcs01120  Microbial metabolism in diverse environments
vcs01230  Biosynthesis of amino acids
Module
vcs_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vcs_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
vcs_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:vcs00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    MS6_2098
   00270 Cysteine and methionine metabolism
    MS6_2098
   00300 Lysine biosynthesis
    MS6_2098
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    MS6_2098
Enzymes [BR:vcs01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     MS6_2098
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     MS6_2098
SSDB
Motif
Pfam: AA_kinase Homoserine_dh ACT_9 NAD_binding_3 ACT_7 ACT
Other DBs
NCBI-ProteinID: BAP03753
LinkDB
Position
1:complement(2380039..2382498)
AA seq 819 aa
MRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGEV
EAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNVNA
RIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRFRQAPLP
QQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIGQDTG
EDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSSEYSISF
CIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVASQFFSSL
AEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMINADQAFSLENLVAL
VQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRNVARHSR
RKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLSQATQLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELSDVDVEQALPAGFDASGSVEEFMA
RLAQADAAFAERVAQAKAEGKVLRYVAQIVDGQCQVRIVAVDENDPMFKVKEGENALAFY
SRYYQPIPLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV
NT seq 2460 nt   +upstreamnt  +downstreamnt
atgcgagtattaaagtttggaggttcatcgctggcggatccggagcgttttctacgcgct
gccgatatcatcgcgaataacgcacagcaggaagaggtggccgttgtcctctctgctccg
ggaaaaaccaccaataaattggtggcagtgattgaaagtgctttacgtcagggagaggtg
gaagcgcaaatcgtagagctagagagctcattctatgccttgcttgatggcattaaagcg
cagctcccgaatttggatgacagtgcttatcaacagcaagtgcactcttccatgactcag
ttacgccagtttgtgcatggcattacgttgctcggtatgtgtccagacaatgtgaatgca
cgcattatcagtaaaggtgaacgcgtttccattcaattgatgaaagcggtgatggaagcc
aaaggtctgccagcgaatttggttgaccccgttaaatacctgcttgccaaaggggatcat
cttgaagctatggtcgatgtggaaatctcgactcagcgtttcagacaagcaccattgcca
caacagcacgtcaatatcatgccgggctttactgcgggtaatgcacagggtgagttggtc
tgtttagggcgtaacggttcggattactcagccgcagtactggctgcctgtttacgtgcg
gattgttgtgaaatctggacggatgtggatggagtttataactgcgatccgcgtttggtc
gatgatgcgcgtcttttgaaatcccttagctatcaagaggcgatggagctttcttacttc
ggagcatctgtgttgcatccgaagaccattgcaccgattgctcaatttcaaatcccttgc
ctgatcaaaaacagcttcaatccacaaggtgcgggcaccttgattggccaagacactggc
gaagataaactcgcgatcaaaggcattaccactctgagcaatctgaccatggtcaacgtt
tctggtccaggaatgaaaggcatggtggggatggcgagccgcgtgtttggcgcgatgtca
gcggcagatgtgtcgatcgtgctcattactcaatcttcttcggaatacagcatcagtttc
tgtatcgaagcacaacataaagctttggcacagcaagcgctggcggatgcatttgaactg
gaactcaaagatggcctgcttgagccggttgagtttgtcgataacgtcgccatcatcacg
ctggttggtgatggtatgcgtacctctcgcggtgtcgcgtcgcaatttttctcatctctg
gccgaagtacacgtcaacgtgattgcgattgcccaaggctcttctgagcgtgcgatttca
gcggtgatccccgatgataagatttcagaagcgatcaaggcctgtcacgaaaacctcttc
aactctaaacactttttagatgtgtttgtggtcggtgttggtggcgtgggcggtgagttg
gtggatcaaattcagcgtcaacaagccaagcttgcggaaaaaggcatcatgatgcgcgtt
tgtggcctcgctaacagtaaaggcatgctgcttgatagccaaggcttgccgttagagcag
tggcgcgatcgtatgatcaatgcggatcaagcgttcagtttagagaatctggtggctttg
gtgcagcgtaatcacatcattaacccagtattggtggattgcacgtccagtgatgagatt
gctaaccagtatgcggatttcctcgccgcgggtttccatgtggtgaccccgaacaagaaa
gccaataccgctagcatgagttattaccatcagctacgtaatgtggctcgtcattcgcgt
cgcaaactgatgtatgaaactacagttggcgcgggtctacccgttatcgaaaacttgcaa
aacctaattgcagcaggggatgagctggaaaaattcagcggtattctctcaggttctctc
tcctttatcttcggtaaattggatgaaggcatgaccttgagccaagcaacgcagcttgct
aaagagaaaggctttacagagccagatccgcgcgatgatctctctggtatggatgtggcg
cgcaagttactgattttggcgcgtgaagcagggtacgaattggagctgagcgatgtggat
gttgaacaagcactgcccgctggctttgatgcttcaggcagtgttgaggagttcatggct
cgtttagcgcaagccgatgccgcgtttgccgagcgagtggcgcaagccaaagccgaaggc
aaagtgcttcgctatgtggcgcaaatcgtcgatggccagtgccaagtgcggattgtcgcg
gttgatgaaaacgatcctatgttcaaagtcaaagaaggtgaaaacgcgctggctttctac
agccgttactatcagccaatcccattggtattacgtggttacggcgcgggttctgaagtg
actgctgcaggcgtgttctcagatgtgatgcgtacactcggttggaaattaggggtttaa

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