Vibrio cholerae O49 1154-74: VAA049_1356 Help Entry VAA049_1356       CDS       T03828                                  Name (GenBank) RTX toxin RtxA   KO K10953   RTX toxin RtxA Organism vcx  Vibrio cholerae O49 1154-74 Brite KEGG Orthology (KO) [BR:vcx00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:vcx02042]     VAA049_1356 Bacterial toxins [BR:vcx02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    VAA049_1356 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACD RtxA Peptidase_C80 MLD RtxA_C Abhydrolase_1 Hydrolase_4 Abhydrolase_6 Abhydrolase_3 DUF1057 Thioesterase Lnb_N Motif Other DBs NCBI-ProteinID:  AKB02757 LinkDB All DBs Position complement(1476938..1490575) Genome browser AA seq 4545 aa AA seqDB search MGKPFWRSVEYFFTGNYSADDGNNNIVAIGFGGQIHAYGGDDHVTVGSIGATVYTGSGND TVVGGSAYLKVEDSTGHLTVKGAAGYADINKSGDGNVSFAGAAGGVSIDHLGNHGDVSYG GAAAYNGITRKGLSGNVTFAGAGGYNALWHETNQGNLSFTGAGAGNKLDRTWSNRYQGSH GDVTFDGAGAANSISSRVETGNITFRGAGADNHLVRKGKVGDITLQGAGASNRIERTHQA EDVYTQTRGNIRFEGVGGYNSLYSDVAHGDIHFSGGGAYNTIIRKGSGNDFAKEGMTNAK ADEIVLTKAVMSGSWIGQDHHVTAVKSASEPNTYLFAFADSTYTKINKVQLRNDPQTGEL KYYSTAWYKEGNHLSNLANQDISDNGGFTAVNINGAYTLSDLKVEHQQSVTVHAVEKSLT EYEWVTYANGAVIDAKEVSLSDAKMGGHAIYADGTKVDVKAVKSNRQPNTYIYAKVLGPY TKIVVVELANDPETGALKYQARSWYKEGDHTANIANQDISSATGYNPMGKGGYSLSDLHY SVNAVRSTSETVADIEEYTDQTLFKPANDSGESSGDVRFNGAGGGNVIKSNVTRGNVHFN GGGIANVILHSSQFGNTEFNGGGAANVIVKSGEEGDLTFRGAGLANVLVHQSQQGKMDVY AGGAVNVLVRLGDGQYLAHLLAYGNISVQKGSGDSRVVMLGGYNTHTQIGSGNGLWLAAG GFNVMTQVGKGDVAAVLAGGANVLTKMGEGELTSGMLGGANVITHISNDDQLSNTTAVAL GGANILTKKGKGNTLAVMGGGANVLTHVGDGTTTGVMVGGANILTKVGNGDTTGIMLGVG NVLTHVGDGQTLGVMGAAGNIFTKVGDGTSIAVMIGAGNIFTHVGEGNAWALMGGLGNVF TKVGNGDALALMVAEANVFTHIGDGMSVALMLAKGNVATKVGNGTTLAAMVGNANIFTHI GHGSTFAAMIGQANIMTKVGNDLTAALMVGKANIMTHVGDGTSLGLFAGEVNVMTKVGNG TTLAAMFGKANIMTHFGDGLTGVLALGEANIVTKVGDDFMGVVAAAKANVVTHVGDATTA AVLAGKGNILTKVGEGTTVGLLISDVGNMMTHVGDGTTIGIAKGKANLITKVGDGLGVNV AWGQANVFTQVGDGDRYNFAKGEANLITKVGDGQEVSVVQGEANIITHVGNGDDYTGAWG KANVITKVGNGRNVVLAKGEANIVTQVGDGDSFNALWSKGNIVTKAGDGMQVTAAKGQAN ITTTVGNGLNVTAAYGDANINTKVGDGVSVNVAWGKYNINTKVGDGLNVAVMKGKANANI HVGDGLNINASYAQNNVAIKVGNGDFYSLAVASSNTSSNKLSALFDNIKQTVLGVGGSQA INYLVQGDEASSSGTHKGRGAIATPEITKLDGFQMDAIKEVGSDLGDSLTGSVTKVDTPD LNKMQHAINVDDSSVQAPNLIVNGDFELGEHGWQSTHGVEASYAGSVYGVEGEGHGARVT ELDTYTNTSLYQDLANLAQGEVIAVSFDFAKRAGLSNNEGIEVLWNGEVVFSSSGDESAW QQKTLKLTAQAGSNRIEFKGTGHNDGLGYILDNVVATSESSQQANAIREHATQNPATQNA LSDKERAEADRQRLEQEKQKQLDAVAGSQSQLESTDQQALENNGQAQRDAVQEESEAITA ELTKLAQGLDVLDGQATHTGESGDQWRNEFASGLLAGVQTQLDDAKQLANDKIAEAKQTH ADNQNKVKDAVAKSEAGVAKGEQNRAGAEQDIADAQADAEKRKADALAKGKDAQQAESDA HHAVNNAQSRGDRDVQLAENKANQAQADAQGAKQNEGDRPDRQGVTGSGLSGNAHSVEGA GETDSHVNTDSQTNADGRFSEGLTEQEQEALEGATNAVNRLQINAGIRAKNSGSSMTSMF SETNSKSIVVPTKVSPEPDRQEVTRRDVRISGVNLESLSAVQGSQQTGQLASKSVPGFKS HFASTSIGIENELSGLVVVLPKNSAQTFGYVHDSQGNPLFMLTKDMNQGGYSNPVGINDI QGVNNWQTHTIELVTYPSEISDTAAVESRKEAMLWLAKEFTDHINQSNHQSLPHLVSDDG RFTLVISNSKHLIAAGNGTSIDAQGKTIGMTPSGQQATMAISAKEFGTSSSPEVRLLESA PWYQAGLRDEFLANAKNTTLDDPATAQNVYAYLTSVYSKTADLAKEYGIYINDWDPASEG FSPNAQGLTDPKVKNAWSILPRTKPVRMLELLSAEDSRYVRQQIAEKLKGTYSESLAKNV FEYFQYGGEVAGHGINNATTGSVQQPEPAVLFEFRSVPSALSDFVPKTASTVKVDVKALD HFDSASRKAIITEVNALVSGSEDFDAWYQEYRASKGQPPVKNPKSSASANHKAEWLMTQH AEQWAKITAPYTDNHGTLTSTKLASNDKEELHALGETSNLENNKQQENVASIINTMLNDM LPFYALRTERNLLVQEGDEGFEVRAWPGTEDKSKTIILEDPEDAAQHKAIERFILANFDN FEQMPDELFLVDNKVISHHEGRTHVLAQRVDGAWQYNAKVELMSVTELLDAAHVTGKIRG ESYQQVIDALTDYHASITEHADYEPESVEKLLNLRKKIEGYVLGHPDSGRVEAMNSLLNQ VNTRLDEVSLLSVAEQTIQAQDSFSRLYDQLEAANLKESKHLYLDQNGDFVTKGKGNLAN IDLLGSREAVLEKVKLTVSNEYGQTVADTIFAGLSAKDLAKDGKGIDIAGLNKVHQAIEQ HLSPVSATLYIWKPSDHSALGHAALQIGQGRTQLEGQAAADFNQQNYVSWWPLGSKSSNI SNILNVATKDQPDLKLRWSDFSQPAHQNDTLEHDVASEENDGFGLHDGDIKLKRFIEKLN AAKGIDASFKEASEGYASVLLGNPDMLETTGIPAHVFQPFVEQWNDTSYDMMDVANRFAQ ELRLQAQRSDDPELLEKRIGNVIRQFAERALEEIETFKASQADQGRVFRINLEGLDVAAM QAEWHRLSNDPDARYQLLTKNCSSTVAKVLKAGGADKLIGHTWLPKFGVWTPTELFNFGQ ALQEAQLEIAAKKQSYQVTDVLDALSGNEKPKENVAIENDGTPPRDKESLSPLTRFLNNE LYGDKEARRKIGEITQTLLDHAVEKGESQKITLQGEAGRLTGYYHQGTAPREGETSSPSG KVVLFLHGSGSSAEEQASAIRNHYQKQGIDMLAVNLRGYGESDGGPSEKGLYQDARTMFN YLVNDKGIDPSNIIIHGYSMGGPIAADLARYAAQNGQAVSGLLLDRPMPSMTKAITAHEV ANPAGIVGAIAKAVNGQFSVEKNLEGLPKETSILLLTDNEGLGNEGEKLRTKLTASGYNV TGEQTFYGHEASNRLMSQYADQIVSGLSSSASVDEDLDQQGLDTTSTKDQGISNKNDHLQ VVDSKEALSDGKILHNQDVNSWGPITVTPTTDGGETRFDGQIIVQMENDPVVAKAAANLA GKHAESSVVVQLDSDGNYRVVYGDPSKLDGKLRWQLVGHGRDHSESNNTRLSGYSADELA VKLAKFQQSFNQAENINNKPDHISIVGCSLVSDDKQKGFGHQFINAMDANGLRVDVSVRS SELAVDEAGRKHTKDANGDWVQKAENNKVSLSWDAQGEVVAKDEPIRNGIAEGDIDLSRI GVNNVDEPARGAIGDNSDVFDAPEKRIPETEVIANSSSSNQLSYSGNIQVNVGEGEFTAV NWGTSNVSIKVGTGGFKSLAFGDNNVMVHIGDGESKHSVDIGGYQALEGAQMFLGNRNVS FNFGHSNDLILMMDKSIPTPPLVNPFDGAARISGVLQGIAMSGEGEDWLAAQEQQWTLSG AKKFVKDMSGLDQSSSVDYTTLVELDSQNERDSRGLKHDAEATLNKQYNQWLSGNGNSGT SQLSRADKLRQANEKLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMT QQFTATGQAKTTFTYTPQDLPRQLKNKLLGQLAGVGAETTLADIFGVDYTASGQIISRNG QAVDGVAILKEMLEVIGEFSGDQLQAFVDPAKLLDSLKAGIDMGADGIKSFAETHGLKEK APEEEKDNSSVSVNGANVNSAQGATVADGNTETAETQDRAFGFNSLNLPNLFATIFSQDK QKEMKSLVENLKQNLTDDLLNMKEKTFDFLRNSGHLQGDGDINISLGNYNFNWGGDGKDL GAYLGDNNNFWGGRGDDVFYATGTSNIFTGGEGNDMGVLMGRENMMFGGDGNDTAVVAGR INHVFLGAGDDQSFVFGEGGEIDTGSGRDYVVTSGNFNRVDTGDDQDYSVTIGNNNQVEL GAGNDFANVFGNYNRINAGAGNDVVKLMGYHAVLNGGDGDDHLIAAAISKFSQFNGGEGR DLMVLGGYQNTFKGGTDVDSFVVSGDVIDNLVEDIRSEDNIVFNGIDWQKLWFERSGYDL KLSILRDPSNDSDQSKFEHIGSVTFSDYFNGNRAQVVIGMSDKDLSGEREYTMLSDSAID ALVQAMSGFEPQAGDNGFIDSLESKSQAAISMAWSDVVHKKGLMV NT seq 13638 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaccattttggagaagtgttgaatacttcttcacaggaaactattccgccgac gatggaaacaacaacattgtagccattggttttgggggacaaattcatgcctacggcggt gacgaccacgtcactgttggatcgattggtgcaacggtgtacaccggtagcggcaacgat acggtcgtgggcggttctgcctatctcaaagtggaagattccactggccacctaactgta aaaggcgcggctgggtatgcagacatcaataaaagtggcgatggcaatgtgtcattcgct ggtgccgccggtggtgtgtcgattgaccatttaggtaatcatggtgatgtcagttacggc ggtgccgcggcttataatggcattacccgtaaagggttgagcggcaatgtcacctttgca ggcgcggggggatacaatgccctctggcatgaaaccaaccaagggaacctgtcttttaca ggagcaggcgcaggtaataaattagaccgtacttggtctaaccgttatcaaggctcgcat ggcgatgtgacctttgatggtgctggtgccgcgaacagcatcagttcacgcgttgagaca ggtaacatcaccttccgtggcgcaggtgcggataaccatttagtccgtaaaggcaaagtg ggcgatattactctgcaaggtgctggggcttcaaaccgcattgagcggacacatcaggcc gaagatgtctacacgcaaacccgcggcaatattcgttttgaaggtgtgggtggttacaac agtctttactctgatgtggctcatggtgacattcatttctcgggtggcggtgcgtacaac accattattcgtaaaggttctggaaatgactttgcgaaagaaggcatgaccaatgctaag gctgatgagattgtattaactaaggccgtgatgagtggctcatggatagggcaagatcat catgtcacagcggtgaaatcggctagcgagcctaatacatatctttttgctttcgcagac tctacgtataccaaaattaacaaagtacagttacgcaatgatcctcaaactggagaactg aaatattactctacggcttggtataaagagggtaaccatctaagcaacttagcgaatcaa gacatttccgacaacggtggtttcacagccgttaatatcaatggcgcctacacgctatct gacctcaaagttgaacatcagcaatccgtcaccgttcatgcggttgaaaaaagcctgacg gaatatgagtgggtgacttacgccaatggtgcggtgattgatgcgaaagaggtgtcattg tcggatgccaaaatgggcggtcatgcgatttatgctgatggcactaaggtggatgtcaaa gcggtaaaatccaaccgccaacccaacacttacatttatgccaaagtgcttgggccttac acaaaaattgtggtggtggaactggcaaacgatcccgaaaccggggcactgaaatatcaa gctcgctcttggtataaagaaggtgatcacacggccaatatagccaaccaagatatttca tctgcaactgggtataacccaatgggcaaaggtggctactcgctcagtgacttgcactac agcgtaaacgccgttagaagtaccagcgaaaccgtagcggatatcgaagaatacacagat caaaccttgtttaaacccgcaaacgatagcggtgaaagctcaggtgatgttcgtttcaac ggtgccggtggcggtaacgtcatcaaatcaaacgtgacgcgtggtaatgtgcatttcaac ggtggcggtattgccaatgtgattttgcatagctcccaatttggtaataccgaatttaac ggtggtggtgcggcgaacgtcattgtcaaaagtggcgaagaaggggatctcaccttccgc ggcgcaggtttggcgaacgtcttggtacaccaaagccaacaaggcaagatggatgtgtac gcgggcggtgcggtaaacgtgttggttcgccttggcgatgggcaatatctcgcgcattta ctggcttacggtaacatttcagtccaaaaaggcagtggtgatagtcgcgtcgtgatgctc ggtggctacaacacccatacccaaatcggctctggcaacggattatggttggcggcgggc ggtttcaacgtgatgacgcaagtcggcaaaggtgatgtcgctgcggtactcgctggcggt gcaaacgtactgaccaaaatgggtgagggtgaactcacgtcgggtatgctgggtggcgcg aacgtaataacccacatcagcaatgatgatcaattatcgaataccacggctgtggcactt ggcggtgcaaatattctcaccaaaaaaggcaaagggaatacccttgcggtgatgggtggt ggcgcaaacgtgcttacccatgttggtgatggcaccacaacgggtgtcatggtcggtggc gcgaatatcctaacgaaagtcgggaatggcgacacgaccggcattatgcttggcgttggc aacgtgctgacgcatgtgggtgatggccaaacccttggcgtaatgggcgcggcgggtaac atcttcaccaaagtgggtgatggaacctctattgcggtcatgattggtgctggcaacatt tttacccatgtgggagaagggaatgcttgggcgctgatgggcggcttgggtaacgtcttt accaaagtaggcaacggtgatgctctcgcgttaatggtagcagaagccaacgtcttcact cacattggtgatggcatgtcggtggcactgatgttagccaaaggcaacgttgcgacaaaa gtgggtaatggaaccacactcgcggcgatggtggggaacgccaacatctttacccatatt ggtcatggcagcacgtttgcggcgatgatcggccaagccaatatcatgaccaaagtgggc aatgatctcacggcggcgctgatggtcggcaaagcgaacatcatgacccatgttggcgat ggtaccagcctagggctgttcgctggcgaagtgaacgtgatgactaaggttggtaacggc accacgttagcggcgatgttcggtaaagccaacatcatgacccatttcggtgatggctta accggtgtactcgcactgggtgaagccaatatcgttaccaaagtgggtgatgatttcatg ggtgtggtggccgcggccaaagccaacgttgtgactcatgttggtgatgctaccaccgcg gccgtattggcgggtaaaggcaatatcctcaccaaggtgggtgaaggtacaaccgttggt ttattgatctccgatgtcggcaacatgatgacccacgttggtgacggcaccaccattggt attgccaaaggtaaggccaacctcattaccaaagtcggtgatggtttaggtgttaatgtc gcttgggggcaagccaacgtgtttacccaagtgggcgacggtgatcgctataactttgcc aaaggtgaagccaacctcatcaccaaagtgggtgatggccaagaagtctccgtggtgcaa ggtgaagccaacatcattactcatgtgggcaatggcgacgactacaccggcgcttggggt aaagcgaacgtcatcactaaagtgggtaatggccgaaacgtggtgctggcaaaaggtgaa gccaacattgttactcaagtgggtgatggcgacagctttaacgcactttggagcaaaggc aacatcgtcaccaaagcgggcgatggtatgcaggtgacggcggcaaaaggccaagccaat atcaccaccaccgtgggtaacggtttaaatgtcactgctgcctacggcgatgccaatatc aacaccaaggtcggtgatggggtatccgtcaacgtcgcttggggcaaatataacatcaac acgaaagtgggtgatggcctcaatgttgccgtgatgaaaggcaaagctaacgccaatatt cacgtgggtgatggcctcaacatcaatgcctcttacgcacaaaacaacgtcgcaatcaaa gtcggtaacggcgatttctacagcttagcggtggcatcaagcaataccagcagcaacaag ctctctgccttgtttgataacatcaaacaaaccgtactcggtgtcggtggcagccaagcc atcaactacttagtgcaaggcgatgaagcctcctcatccggcacgcataaaggtcgtggt gcgattgctacacctgaaatcaccaaactggatggtttccaaatggatgccattaaggaa gtcggttctgacctcggtgatagtctcacgggcagcgtgactaaggttgatactcctgat ctcaacaagatgcagcatgcgatcaatgttgatgattcttctgttcaagctccgaatctg attgtgaatggtgattttgagctgggcgaacatggctggcaatctactcatggggttgaa gcctcttatgcaggcagtgtgtatggcgtagagggtgaaggtcacggcgcacgtgtgacc gagctcgatacttataccaacaccagtctctatcaagatctggctaatctagcgcaaggt gaagttattgcggttagctttgattttgcaaaacgcgcgggcctttctaataacgaaggc atcgaagttctttggaacggtgaagtggtattctcatcgtcgggtgacgagtctgcttgg cagcaaaaaaccttaaagctgaccgcgcaggctggcagtaaccgtatcgaattcaaaggc acaggccacaatgatggactgggctatatcctagataatgtggtggcgacatcagagtca tcgcaacaagccaatgcaatccgtgagcacgcaacgcaaaacccagcgacgcagaatgct ctatccgataaagagcgtgcagaagcggatcgccaacgtctagaacaagaaaaacagaaa cagcttgatgctgtcgcaggttcacaaagtcagttggagtcgaccgaccaacaagcgtta gaaaataacggtcaagctcaacgtgatgcggtgcaagaagaatcagaagctatcacagct gagttgacaaaactggcgcaaggtctcgatgtgcttgatggccaagcaacgcatacgggc gagtcaggcgaccaatggcgtaacgaatttgctagcggtctgctggctggcgttcaaact caactcgacgatgcgaagcagctcgcgaatgacaagattgctgaggcgaagcagacgcac gcggacaatcaaaataaagtgaaagatgcggttgcgaagtctgaagcgggagtcgccaaa ggcgagcaaaatcgagcgggagcagagcaagatattgctgatgctcaagccgatgctgaa aaacgtaaagctgatgctttagcaaaaggtaaggatgcgcaacaagcggaatctgatgca catcatgcggtaaataacgctcaatcacgcggcgatcgtgatgtgcaattggcggaaaac aaagccaaccaagcgcaagctgatgctcaaggtgctaaacaaaacgaaggtgatcgtcct gatcgtcaaggcgtgactggtagtggcctttcgggtaacgctcatagcgtggaaggcgct ggcgaaacagacagtcatgtcaacaccgacagccaaaccaacgccgatggccgattcagt gaaggtttgaccgaacaagagcaggaagcgctagaaggtgcgaccaacgcagtgaaccgt ttgcaaattaacgcaggtattcgagcgaaaaacagcggtagcagtatgacttctatgttc tctgaaacaaatagcaagagcattgttgttcctaccaaagtctcgcctgaaccagatcgc caagaagtgactcgtagagacgtccgtatctcaggggtgaacctcgaaagtctaagtgcg gtacagggaagtcaacaaacgggtcaactggcttcgaaaagtgtccccggatttaaaagc catttcgcatcgacatccattggtatagaaaatgagctatccggtctggtggtggtttta ccgaaaaactcagcgcagacttttggctatgtgcatgattcacaaggtaacccattgttc atgctaaccaaggatatgaatcaaggtggttatagcaacccagtgggtatcaatgatatt caaggggtgaacaactggcagacgcatacgattgaactggttacatatcctagtgaaatc agtgatacagcagcggttgaaagtcgtaaagaggcaatgctatggcttgcgaaagagttt accgatcatatcaatcagtctaaccaccaaagcttacctcatttagtgagtgatgacggt cgtttcacactggttatatcgaactctaagcatcttatcgcggcgggtaacggaacctct attgatgcacaaggcaagaccataggaatgactcctagtggtcaacaagcaacaatggcg atcagtgcgaaagaatttggtacaagctcgtcgccggaagtcagactgcttgaatctgcg ccttggtatcaagcagggttgagagatgagtttttagcaaacgcgaaaaacaccacgttg gatgatcccgctacagcacaaaatgtgtatgcctatctcacgtctgtctattcaaaaaca gcagatttggccaaagagtatgggatctacatcaatgattgggatcctgcctctgaaggt ttttcaccgaatgctcaagggttaacggatccgaaagtcaaaaatgcttggagcatattg ccaagaactaaacccgttagaatgctggaacttctgagtgcggaagactcacgctacgta aggcaacaaattgcggaaaagctgaaaggcacctattcagaaagccttgctaagaacgtg tttgaatacttccaatatggtggagaagtcgctggacatggaatcaataatgcgacgaca ggaagtgtgcaacagcctgaaccagcggttttatttgagtttcgcagtgtaccgagtgca ttaagtgactttgtacccaaaacagcgtcaacggtgaaagtggatgttaaggcactcgat cattttgactcggcaagccgtaaagccatcattactgaagtaaatgctttggttagcggt agtgaggatttcgatgcttggtatcaggagtatcgagcaagcaaaggacagccgccagtc aaaaatcctaagtccagtgcatccgccaatcacaaagctgaatggttgatgacgcagcat gctgaacaatgggcgaaaattaccgctccttatactgataaccatgggacgctcacatct accaagcttgcttctaacgataaagaagaattacacgctttaggtgaaacgtcgaatcta gagaataacaagcagcaagaaaacgtcgcttccataattaacaccatgttaaatgacatg ctgccattctatgcactgcgtaccgaacgaaatctactggtacaagaaggagatgaaggc ttcgaagtgcgtgcttggccaggaaccgaagacaagagtaaaaccattattcttgaggac cctgaagacgcggctcagcacaaagccatcgaacgcttcattctggccaacttcgataat ttcgaacaaatgccagacgagctcttcttggtggataacaaagtgatttcacaccatgaa ggtcgtacacatgtgttggcacaaagagtcgatggtgcatggcaatacaacgccaaagtg gagctgatgtcagtcactgaactactggatgcggcgcatgtaacgggtaagatccgcggt gaaagctatcagcaagtgatcgacgcattgactgattaccacgccagcatcactgagcac gcagattatgaaccggagtccgtggaaaaactgctcaacttgcgtaaaaaaattgaaggc tatgtactcggacacccagactcaggtcgtgttgaagcgatgaattcactgttaaatcag gtgaatacgcgtttagatgaagtttcactgctgtcagttgctgagcaaactatccaagcg caagacagtttcagccgactatatgaccagctagaagccgctaacttgaaagagagtaag cacctttatctggatcaaaatggtgactttgttaccaaaggcaaaggtaatcttgctaat atcgatctgctaggtagccgcgaggctgtgcttgaaaaagtgaagttaacagtaagtaac gagtacggtcaaaccgttgcggatacaatttttgctggattatcagccaaagatcttgcc aaagacggtaaagggattgatatcgcgggtttgaataaagtacatcaagcgattgaacag catctgtcacctgtcagcgccacgttgtacatttggaaaccgagtgatcatagcgcgcta ggtcatgccgcattgcaaataggccaaggtcgcacgcaacttgaaggtcaagctgcagct gattttaaccagcaaaattacgtaagctggtggccactaggcagcaagtcatccaatatc agcaatatcttgaatgtggccacaaaagaccaacctgatcttaagctgcgctggagcgac ttcagtcaacctgcacatcaaaatgacacgcttgagcatgatgttgcttcggaagaaaac gatggctttggtttgcatgatggcgacattaagctgaaacgctttatcgagaagctcaat gccgcgaaaggaattgacgcttcatttaaagaggcttctgaaggttacgcgagcgtacta ctgggtaacccagatatgctcgaaacgacaggtattcctgcacatgttttccaaccattt gtcgaacaatggaatgacaccagttatgacatgatggacgtggcaaaccgttttgcgcaa gagctcagactacaggctcaaagaagtgacgatcccgaactgcttgaaaagcgcatcggc aatgtgattcgccaatttgcagaaagagcactggaagagatcgaaaccttcaaagcaagc caagccgatcaaggtcgagtattccgaattaaccttgaaggcctcgatgtggcggcaatg caagcagaatggcatcgtctaagcaacgatccggatgctcgttatcaattactgaccaaa aactgctccagcacagtggctaaagtgttgaaagccggtggggcggataaactgattggc catacatggctgcctaagtttggtgtttggacgccgaccgagcttttcaactttggtcag gcactgcaggaagctcagctggaaattgcagcgaagaagcaaagttatcaagtcactgat gtccttgatgccttgtcaggcaatgagaagcccaaagaaaacgtggcgattgaaaatgat ggtacgccaccgcgcgataaagaatctctgagccccttgactcgattccttaataacgag ttgtatggtgataaagaggctcgccgtaagattggcgaaatcacgcaaaccctacttgat catgcggtggaaaaaggtgaatcgcagaaaatcactctgcaaggagaagcgggccgtcta acggggtattaccatcagggaactgccccaagggaaggtgaaacgagctcgccaagcggc aaagtcgtattgttcctgcacggttctggttcttctgctgaagagcaagcgagcgcgatt cgaaatcactaccagaagcaaggtatcgatatgctcgcagtcaacctgcgtggctatggt gaaagcgacggtggaccaagcgaaaaaggcttgtaccaagatgctcgcaccatgttcaac tacctagtgaatgataagggtattgacccaagcaacatcatcattcacggctactcaatg ggcggtccaattgccgcagatttagcacgttatgccgcgcaaaacggccaagcggtgtct ggcttattgcttgaccgtcctatgccaagcatgaccaaagccatcaccgctcacgaagtg gcgaatccagcgggcattgtgggggctatcgcgaaagcggttaacggccagttctctgta gagaaaaatctcgaaggtttgccaaaagagacatccattctgctgttgaccgataacgaa ggtttgggtaacgaaggtgagaaacttcgtactaaactcactgcctctggttacaacgtc actggtgaacagacattctatggtcacgaagcaagcaaccgtttgatgagtcaatatgcg gatcaaattgtctccggtttgtccagcagtgcaagtgtagatgaagacttagatcaacaa gggttggataccacatcaaccaaggatcaaggcatctcaaataagaatgatcatctgcaa gtggtggatagtaaagaagcattatcggatggaaaaatactccataatcaagatgttaat agctggggccctattacggttacaccaacgacagatggtggtgaaacccgcttcgacggt caaatcatcgttcaaatggaaaacgacccggtagtagcaaaagcggcagccaatttagca ggtaaacatgctgaaagcagtgtggtggtgcagctcgattcagacggcaactatcgcgtg gtgtatggcgatccgtcaaaactggatggaaagctacgctggcagttggtggggcatggt cgcgaccactcagaaagtaacaatactcgcttaagtggttacagtgccgatgagttggcc gtgaaattggccaagttccaacagtcgtttaatcaagccgaaaacatcaacaacaaaccg gatcacatcagtattgttggttgttctttggtgagtgacgacaagcaaaaaggctttggt catcagtttattaacgcgatggatgcgaatggtcttcgtgtcgatgtctctgttcgtagt tctgaactggccgtagacgaggcgggacgtaagcataccaaggacgcgaatggagattgg gttcaaaaggcagaaaacaacaaagtttcgctaagctgggacgcgcaaggtgaagttgtt gccaaggatgaacctattcgcaatggtattgcggaaggcgacatcgatctctctcgtatt ggtgtcaacaatgtcgatgaacctgctcgtggcgcgatcggtgacaatagtgacgtgttt gatgcgccagaaaaacgcataccagaaacggaagtgattgccaattctagcagcagtaat caactcagctactcaggtaacattcaagttaacgtgggtgaaggggagtttacggcggtg aactgggggacatcgaatgtgagcattaaagtcggtactggtggctttaaatcgctggcc tttggtgacaataacgttatggttcatatcggtgacggtgaaagcaaacacagtgttgat atcggtggctatcaagcactggaaggtgcgcaaatgttcctcggtaaccgtaatgtgagc tttaatttcggacacagtaatgatctgatcctaatgatggataagtcgatcccaactcca ccactggtcaatccattcgacggtgccgcacgtatttctggtgtgctgcaaggtattgct atgtctggagagggagaagattggcttgccgctcaagagcagcaatggacactgtctggc gcgaagaagttcgtcaaagatatgtctggtttggatcagagcagcagtgtggattacacc acattagttgaattggattcacaaaatgaacgtgatagccgtggcctgaaacacgatgca gaagcgacactgaataagcaatacaatcagtggctaagcggtaacggtaatagtggcacg agtcagctcagccgcgctgataagcttcgtcaagccaatgaaaagctagcatttaacttt gccgtaggtggacaaggggcggatattcaagtcacgacgggtaactggaactttatgttc ggcgataacattcagtcgattttggataccaacttaggttcactgtttggtctcatgaca cagcagttcaccgcaacgggacaagcaaaaaccaccttcacttatacgccacaagatttg ccgcgtcagctcaagaataagctactcggccagttggcaggagtaggggctgaaacgaca ttggcggatatttttggtgtggattacaccgcgtcaggtcaaattatttctcgtaatggt caagccgtcgatggcgtggcgattctcaaagagatgctggaagtcatcggtgagttcagc ggagatcaactgcaggcttttgtcgatcctgctaagttgctagatagcctgaaagcgggt atcgacatgggagcggatggcattaagtcttttgctgaaactcatgggctgaaagagaaa gcgcctgaagaggaaaaggacaattcttcggtttctgttaatggtgcgaatgtgaacagt gcgcaaggtgcgaccgtggctgatggcaatactgaaacagcagaaacacaagatcgtgcc tttggctttaactcgcttaacctgcctaacttgtttgcgactattttcagccaagataag cagaaggaaatgaagtcactggtggagaatctcaaacagaatctcaccgacgatctgctg aatatgaaggagaaaacgtttgattttcttcgtaatagtggccatctccaaggtgatggt gatatcaacatctccctaggaaactacaacttcaactggggtggtgatggtaaagatctc ggtgcgtatctcggagataacaacaatttctggggcggacgaggcgatgatgtgttctac gcaacaggcacatcaaacatcttcacgggtggagaaggcaacgacatgggcgttctgatg gggcgtgaaaacatgatgtttggtggcgatggcaacgacacggcagtggttgctggacgc attaaccatgtcttccttggtgccggtgacgaccagtcgtttgtctttggcgaaggtggt gaaattgacaccggttcaggccgcgactatgtggtgacttctggcaacttcaaccgtgtg gatacgggagatgaccaagactactccgttacgattggcaacaataaccaagtggaactc ggagcaggtaatgactttgccaatgtttttggtaactataaccgtatcaatgccggtgcg ggtaacgatgtggtgaaactgatgggttaccatgccgtgctaaacggtggtgatggagat gatcacctgattgcagcggccatctctaagtttagccagttcaacggtggtgaaggccgt gatctgatggtacttggtggttatcaaaatactttcaaaggtggcacggatgtggacagc tttgtggtgagcggtgatgttatcgacaaccttgtggaagacattcgcagcgaagataac attgtcttcaatggtatcgattggcagaaactgtggttcgagcgcagcgggtatgacctg aaactgtcgattttgcgtgatccgtctaacgacagtgaccaatcgaagtttgagcatatt ggttcggtgacattcagtgattactttaatggtaaccgcgctcaagtggttatcgggatg agtgataaagacctgtcgggtgaacgtgaatacaccatgttatcggatagtgcgattgac gctctggttcaagcgatgagtggttttgaacctcaagcgggtgacaatggctttatcgac agcctagagagtaaatctcaagcagcgatcagcatggcgtggtcagacgtggttcacaaa aaaggattgatggtgtaa

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