Vibrio cholerae O49 1154-74: VAA049_2870
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Entry
VAA049_2870 CDS
T03828
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
vcx
Vibrio cholerae O49 1154-74
Pathway
vcx00230
Purine metabolism
vcx01100
Metabolic pathways
vcx01110
Biosynthesis of secondary metabolites
Module
vcx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
vcx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
VAA049_2870 (purL)
Enzymes [BR:
vcx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
VAA049_2870 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AKB04030
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Position
complement(3174331..3178224)
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AA seq
1297 aa
AA seq
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MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY
GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLRGIKRLERGTAYYVEAETALT
AAQITTLKTLLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL
ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM
IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPDSRQYTYHHEEAHILMKVETHNHPT
AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV
NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI
RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR
CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL
EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM
PMDILLGKPPKMHREASTLKVASPALERSGIALNEAVDRVLRLPAVAEKTFLITIGDRSV
TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI
TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS
MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL
GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA
FAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAYVIGEV
EASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLN
AKLTYDLQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTG
QTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGC
QMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGE
GRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMM
PHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgagaattttgcgtggctccccagctctttcagagtttcgtgttaacaagctcctgacc
gcgtgtcgtgaacagcaactgcctgtaaccggtatttacgccgagtttatgcactttgcc
gatctcaaggcagagctcaatccgcaagagttggaaaagctcgaaaaactgctcacttat
ggtccaaccattcaagagcatgaaccgcaaggtttactgctgttggtgacgccgcgcccc
ggaaccatctcaccttggtcctcaaaagccaccgatattgcacacaactgtggcctgcgt
ggtatcaaacgtcttgagcgcggtacggcttattatgttgaagcagaaacggcactgacc
gcagcacaaatcacaacacttaagacactgttgcacgatcgcatgatggaagtggtgttc
gcagaactcaccgatgcgcagcaactgtttagcgtggcagagcctgcaccgatgagtcag
gttgatgtgttggctggtggtcgtcgtgcgcttgaagaggcaaacgtttcccttggtctg
gcactggcagaagatgaaattgattatctggttgagagcttcaccaaactgggtcgtaat
cctaacgatattgaactgatgatgtttgcacaggcgaactcagagcactgccgtcacaag
atcttcaatgcagattggaccattgatggggttaaacaagataaatcgctgttcaaaatg
atcaaaaacacctttgaacagacgcctgattatgtgctttcggcttataaagataatgcc
gcggtaatgactggctcgactgttggccgtttcttccctgatcctgatagccgtcagtac
acctatcaccatgaagaagcccacattctgatgaaagtggaaacgcacaaccacccaacg
gcgatttcgccttggccgggtgcgtcgacaggttcaggcggtgaaatccgtgatgaaggc
gcaactggtattggcggcaagcccaaagcaggcttggtcggttttaccacatctaacttg
cgtattcccggctttgaacagccatgggaaagcgattttggtaagccaagccgcatcgtc
aatgcgctggatattatgctggaagggccactcggcggcgcggcgttcaacaacgaattt
ggtcgcccgaacctgctaggttatttccgcacttatgaagaaaaagtgacttcacatgcg
ggtgaagaggtacgtggctaccacaaaccaatcatgatcgctggcggtatgggtaacatc
cgtgcagaacatattcagaagaaagagatcccggttggtgcaaaactgatcgtgctcggt
ggccctgcgatgaacattggcctcggcggtggcgctgcctcttcgatggcttctggccag
tctgctgaagatctggattttgcttctgtgcagcgtgaaaacccagagatggagcgccgc
tgtcaggaagtgattgaccgttgttggcagctcggtgacaaaaacccgatcgcctttatc
cacgatgtgggcgcgggtggtatctctaacgctctgcctgagctggtgaatgacggcgat
cgcggtggtaaattccagctgcgcaacgtgccgaatgatgagccgggcatgagcccattg
gaaatctggtgtaacgaatcacaagagcgttatgtgctggcggttgctgcggaagatatg
ccgctgtttgatgccatctgtcagcgtgaacgcgcaccttatgctgtggtgggtgaagcg
accgaagagcgccatttgacgctggaagacagccactttgctaacacgccgattgatatg
ccgatggatattctgctgggtaagccgccgaaaatgcatcgtgaagcgagtacgctgaaa
gtggctagcccagccttagagcgttcaggcattgcgcttaatgaagcggtggatcgcgtc
ctacgtttaccggcagtagcagaaaaaacgttcctgatcaccatcggtgatcgctcagtg
actggcttagtcgcgcgggatcaaatggtcggtccatggcaagttcccgtcgcaaactgc
gcggtaacggccgcgagttttgattcttaccacggcgaagccatgtcgatgggggagcgt
acccctgttgcgctgctggatttcggtgcctccgcacgtttagcggtcggtgaagccatt
accaacattgccgcaaccgatattggcgagctgaaacgcatcaaactttcggcgaactgg
atgtctccagcgggccatccgggtgaagatgccggtctgtatgaagcggtgaaagcggtc
ggtgaagagctttgtccagcactgggtatcactatcccagtcggtaaagactcgatgtcg
atgaaaaccaagtggcaggaaaatggcgagcagaaagaagtgacttcgccgctgtcactc
atcatcactgctttcgcacgtgtggaagacattcgcaagaccgtgactccacaactgcgt
actgaccttggtgagacaagcttaatcttgattgacttgggtaatggtcaaaatcgtctt
ggcgcaaccgcattagcgcaagtgtacaaacagttaggtgataagccggctgatgtggat
aacgcggcgcagctcaaaggcttttttgatgcagtacaaacgctggtgcgtaacgacaag
ctggtggcttaccacgacaaaggtgacggcggtttattggtgacgttggcggaaatggcc
tttgcgggtcattgtggtatcaaagctaatattgaaaccttgggtgatgatgcactggcg
gcactgttcaatgaagagcttggcgccgtggttcaagtgaaaaatgatgagctgaatgct
gttctggcaacacttgccgcccatggtttagaagcgtgtgcttacgtgattggtgaagta
gaagcatccgatcgtctgctgatcacttgtggtgaggaagtcttgattgagcgctctcgt
actgagcttcgcaccatctgggcggaaatgacccataagatgcaagcgctgcgtgataac
tcagcctgtgctgatcaagagtttgcggccaaacaagataaccgtgacccgggcttgaat
gcgaagttaacttacgatttgcaagccgacgttgctgcgccgtacatcgccaaaggtgtg
cgtccgaaaatggcgattttgcgtgagcaaggcgtcaactcacacgttgagatggcggca
gcgtttgaccgcgctggttttgatgcggttgatgtgcatatgagcgatattctgactggg
caaaccgtgctcgatgcttaccaaggtctggtggcttgtggtggcttctcttacggtgac
gtattgggtgcgggcgaaggttgggcgaaatcgatcctgtttaacgcccaagcgcgtgag
cagtttgagcagttcttccaacgtaaagataccttctcacttggggtgtgtaacggctgt
caaatgctgtctaacctgcgtgatttgatcccgggtgctgagctatggccacgttttgtg
cgtaacgaatcggatcgttttgaagcgcgctttagcttagtcgaagtgcaaaaatcgcca
tcgctattctttagcgagatggcgggctcaagaatgccgattgcggtttctcatggtgaa
ggtcgtgtggaagtgcgtgatgctcagcatctggcggcaattgagcaatctggcaccgta
gcgattcgtttcgtggataactttggtcagccaacccaagcttacccaagcaacccgaac
ggttcaccgaatgcgattaccggtttaaccactcaagatggccgtgtgacgattatgatg
ccgcaccctgagcgtgtattccgtaccgtcgccaactcgtggcacccagataactggggt
gagaatggcgcttggatgcgtatgttccagaatgctcgtaaatattttggctaa
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