Varroa destructor (honeybee mite): 111248727 Help Entry 111248727         CDS       T07383                                  Name (RefSeq) midasin-like   KO K14572   midasin Organism vde  Varroa destructor (honeybee mite) Pathway vde03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:vde00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     111248727  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:vde03009]     111248727 Ribosome biogenesis [BR:vde03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     111248727 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 AAA_22 nSTAND3 TsaE AAA_6 AAA_14 MDN1_4th Sigma54_activat AAA_18 ABC_tran Sigma54_activ_2 AAA_30 bpMoxR Dynein_heavy AAA_25 Rad17 AAA_19 TniB DUF815 PduV-EutP VWA_2 TIP49 Motif Other DBs NCBI-GeneID:  111248727 NCBI-ProteinID:  XP_022657303 UniProt:  A0A7M7JXZ8 LinkDB All DBs Position Unknown AA seq 5070 aa AA seqDB search MISKELQPRLETLQEVCRACGKTVEARYSKEKISFVESLSAQLLVNGHSQHIQEVFPDLL VDLLNRLRSTACIEEVGCALSSLIVNRNYNSRQIISWAEEFFTTKDTASLLARFSVTEQP PTKKSKKLSSNISDLDVLRTAYVLLCTNPDLYRSLWDWSCLTHILQESQKSETVENNPVL QWIACHCLALVCRLSPSDLDNLLRRHIKNEEVFISIRQNEFHSSIETKTRLSFEPISSLG ERRCHTINVEGITLMKKWQPDTKENQSQIQQKSDVSTLPSIVRTPSICSALRETASAIVS LRPVLITGSIGVGKTLLVEELARMTGNRLVKVQLGNHADSKMLVGSYCCTDIPGKFCWQP GLVYQAVTNGQWLLLEDLDFAPVDIVTLLMPLIQERRLPGVNLDGGLTAASGFRLFTTMR LLGGDKAHGRVQHQGHSEMVGSCQAIEGLLTKVHVSSPNDAELEQILGSHAPILQPFLPK IIHLYRRLQTRLQEEGHCKRVISLRDLVKLAKRLAENFRLDCSNPEELFLDAVDCLIEFI DSPSLKLSLAQAYLGPIFNMGPNDVKHIVEQRKPNVQLDEKSITVGRCSVSKRPLMTAME KLQLQEYGTTGDKFAPTRVSLNVLEKIIRCITCKEPVLLVGETGTGKTTVVQYLARHTNN RLTVINLNQQTDIVDLIGGFKPVASTFTVLNFINELRDLLNVRKKLLEGNRSFLETLMIS YERKALGKVCAAISETCKQMADAVNASIIQIGGNWQEKLKDLGMRAHAVMTQLASDKLGN ERMSFAFIEGSLVKAMRRGDWILLDEINLAETEMLECLASILEYGQLLLQEKGEADPVQC HPNFRIFACMNPATDVGKKDLPVGIRNRFTELYFEEIVQFPDLQLVAHSYLGGASPVVVG QCVDLYLRLRELGRTKLADGTGHRPHYSLRTLCRATRFAGRMIQDCQQADRAIYEGFCLS FITQMDPVSHKLVQNEITRAILGPKAASLLGEQLKQPSGGNFVQLEGYWVPCGDEKPQTP EDYILTNTVRENLKDLARAVSARQHPVLIQGETSVGKTSLITYLAKCTGNKCVRVNNHEH TDITEYIGQYIADKNGALVFKEGVLVEAMRKGHWIILDELNLACSEILEALNRVLDDNRK LFISESQTEVTAHPKFMLFATQNPPGTYAGRKVLSRAFRNRFIELHFNELPPSELVTILS KRCAVSPTHATKMIRVMSELQLERKGSGIFAGKQGFITLRDLFRWAERYRRVERTGFHDW DQLLADEGYMLLAGRVRRNEEEQIICRALRKVFKREVDRDALWSSSDTTKSVREMLDKWE CETSACDKDNFAHVVWTKNARRLAVLVGQALKFGEPVLLVGETGCGKTTVVQLFARMHGR RLYSVNCHMHSEAADFIGGLRPYRGRTSTDELSKENYTETESNDDSGRLFEWNDGPLVKA MQSGDFFLADEISLADDSVLERLNSLLEIEKTIFIAEKGDGVCISAAANFWFASTMNPGG DFGKKELSPALRNRFTEIWCPSNLCDDDLLCVIQHNLAENDSVNEQAKQWIANGMMEFMR WFEQEEFGKRTVISLRDILSWVNFINVYAHRLNAETAFVHGAAMIFLDSLGTRNASEQGD NLKTARTKALGVLMASMPNPDLCLLEDQCLSIRVTDKHLAVGPYKLLKHAGAPTRLLEFN FSAPTSCSNAMRILRAMGLQKPLLLEGVPGVGKTSIVIALAKQCGKQITRINLSEQTDIA DLFGADLPVEGGVGGRFRWRDGPLLRALKRSDWILLDELNLASQSVLEGLNACLDHRGEI FVPELSRTFAVKRGQTRIFGCQNPHRQGCGRKGLPKSFLNRFTQVYMEPLTEEDLYLILR LLFPSLDAGQLKSMVQFNSVLCDEVQTRGLWGHNGAPWEFNLRDMCRWADMVIRHKMRPS ELVSFVYADRMRSEADRQKVADICQVVFGEKMARPFPKLRLTSDWLQVGGFLLQRSYNTG FESLSEDVANLRLLRSQRRVIESIVMCLNQGTMCILVGPAGCGKTSSVKSLCALLGRKLT VLPVTSEMDTIELLGGFEQVDLNRALSEVINRAIEQVRLMIASHLNDNSLGKAEVLLKGL YSLSKEYSLYCSGTESTKTENPVDAFVQRIAVVRAFVSRIPLASLLPQLTRLEALVKEHK SLTCGGRFTWVDSPFVRALQNGDWLLLENVNFCAASVLDRLNCLLEKDGVLTISEAGVQD GELRTIVPHPDFRLILTMDPRNGEISRAMRNRGHEVYMLPFDDTIDEWDFVSLLEAKGCL DEALAKKCWSIVSNIRHQSVSYGLVNQMVRAVDAMEQESRWGTLTIAALAKLLVRYIKPL VADSDIEVLVRSHLSGIEHTIKSRQRTASVQNYVHGGNMAEHFEDSIIFSQKRSQTDSFE MQQFRTGMVQQLYFENLALSDIPVKLSFVHSSIVVGIVMTLTNEFSQRLSNYPRDLCIDY RFNPCLAKQFQAKNPWANTFVFALMKDVLYAQLPLKCDSEICDTYLGISARHKDTLPHVL IGMLPHLIDTLEGLLEQKKSIKMSDQQLVAAKRSLYGVWRFKQKANQPVRFVDRDISVMA VVLLWALKRLIILSDTNREENDKIIKLVRQLERLVPDLFSRARKLRETTVRAVGIPAVMK TQSQAELFHRALSIEFLTNNTSERVATELADEDEAVVACAIEELERMSAPMKQAANEIIV DIVETGSVLRKQEIEDIEDKLKQFVEGLQRFDNNYVLIAPYNHDQRLHKHLRPVYEVLDI RRSMAALNASHPEFIPNFVELAVRSWSCMADLDVHLNWTPPHIISTLTTGVRSVKQRIMD GKRKMHSSALVFNHPAITHCIGPLVDAETNNANLDLDYSQMKLRELEEIRRLLWEYVTVE TKFADQNQIAMQKIASAIRPILEENHASLTEGMVHALLAVKTVEQEIKANPQNAKRNILV QQIRVAHLLVQIFTPFDVMDPYEKVALKKDYLSGEESVLVDELRIRQWLQIRRTACDTLD QHPAYLNNTVICKAINEKLQNLEKRTAYRPEKSQYPEIAQVMQQYVKRNANTEIVDKMLN CVLSGKDATATFDTWLINQKSFILTMRRAYPFYRDIVYPFLFGASQLVNCFEALYKFIQN DQSQSTVSEIVQFPRVAVISSPLLKNITTLILNDAEKGNTQENLQKVWKLKFRESKADLL EVLDALRMSSGDREKLIGKVDRIVSWLTAQYAEFAAAEAERELTKDSLYEMRTNEYKGEE NDEVLQAKAIAAMFPNFDEVYEDITDDRDFLNQEKRLEKSTEHQDNESSSLGKFSDEDLL MIHRIVLEIVRTASSTERSSPADIVSCLLERFRLFQLLSDNFKDWLNIEVDDQAVAAHLI ASVSMTWVISGNEDKLHSYAKIDSRTGQQVDFYRDANIAEIIKCQPVLHQIISRTKELLT EFETHHGLVQVLKVSYRVLSLPITSPLMKVLAGLVRVLTEIEEWNKNVPRHMKMAAEMTS LAHLIISWRKLELSSWSGLLDSALEKRKVEAAKFWLRLEHAVSDQHDVVVEDADDAQHTR QKEVVRTAVTLMEATTTLGDFSYKLEMLSQLASYVKARKRSGDDKVYSALSNVHSYYMQF LPVIEEKIESTRRAINKDINDYIKIVRYKDTSYLAIKQSAEKSHKKLHYCLRNFEKVIQE PAICYLKQQNDADFASAPIRSRKKKKITELRRIDLANFYVKAVDLKVPASHNVEYSNIPF YHRLARKYLREAFEASHVQSIADILDDVASDIAENMSKLAKETEKQIRHDDKQAKKKAKS LLQRKKKMLTTLFRQLTKCGLSYRKGVLLYQKVKAIDLVATPLLESSEVPDAVQEYVDDV NAYFFKSVQKYSDLQTAMEMPSKELELYVVERLQGFSSHLFEQITSASHHLIKLSRYAFE LRKHLVKLKDVAACERIPEQAHNAMRRTEMLSLLLKLCSCLQQFVVLIETLPTTEMETSV KVLQTKELAQKTRTTLVENITAIQERIRLFEAMDPAPLSEREVLVLDETETVLRGMHLKL NFVISSLEAGKANCITSPYYDLLKDISRTLKATQRRTLEEDDAKAALRSVDEAMTKCLKK VLLTVQNVFKAYEQTPVLDQDDNTTNILNMLVNEKVKLLDNFDLQGVLRSFTTFQQKLVW LNVEIPSNNLSSFTAFMENFSLNFEHAFACAVKAQRAKLKLLYLVLCVSVQLTQKGFCIP EEFRDDLMKEGATQLQDIEDGGLGEGEGQKDTSDKIDCEDQLEEAHQKEQKPHEKNEDEN QKDIDDEKEGIEMSEDFDAKAQGPDEINIDQKNDEDKDEEQDEDQLDDQMGDVENNNPFD LDKKMWDKEQDEENQDLSSDDDAQGGEELQEESQMVAKDDKARETEKDSKSKDEKPFPDE DDENQINEMDDEYEGEKEDPYKSGKQAGMDEDNEVEDFQLPENLIETEEMEEEGSEGKDD ADDISDRGKAENDEDTEAPADEELSDLPEEVNEPVDDGDPSKAEQEEEKIENPDSIEDKR DASVDDALDKTDKNVPQIIHAKGDRSAAQTAEQPVDQRGECMQTSEDIDGSGEGQSSSAN TEDMGNTTDRAREDASQTKGASREKQKKSSNERKIALQMPQHKDLINGNISQAVDHEKQS GLEKGSEFEHQHKDDENADIEEVAVDMATDEQAEKTQPVAANETEQAESEGSDSGMEDIG VNDSEDPMSVDDQEANDKRKEQTYQQQQRTKDKGKIPKLPKSEPGPEGEAQFKNGDLVRT QTVQRGNQAVVETRTDLLFEKVEAVNLGVQAICPEEFSCDLAECRRVWAEAEKSVSLLVQ ELCEQLRLVLELTKASKFKGDYRSGKRLNMRKVIDYVASGFRKDRIWMKRTKPNKRQYQI LLAVDDSASMSDSKAKEMTFETVALLANALNFLEAGELSVASFGVNVSLVHPLGESWISD SGAHLVRSFTFSQTETRVSNLISFATDMFEKSRSSINGNPVQRETAQLLIIVSDGRLMSE GTELVKGTIRRARENGIFIVYLLLDNPTAIQGSIMEMQRASFDATTQQPILCRYMESFPF PFYVVLRELDSMPVVLGEALRQWFELVTGK NT seq 15213 nt NT seq  +upstreamnt  +downstreamnt atgatatcgaaagagctgcagccgaggctcgaaaccttacaagaggtatgccgggcctgt ggaaaaaccgtggaagcacgatactcgaaggaaaaaatatcttttgtcgaaagtttgtct gcacagttgcttgtcaacggtcatagccagcacattcaggaggtgtttcctgatctgcta gttgacctgctgaatcgcttgcggagcacggcttgcatagaggaagtcggatgcgctttg tccagtttgattgtgaatcgtaactacaactcacgacagatcatcagctgggcggaagag tttttcacgacaaaggacactgcgtcattgttggcccgcttctctgtcacggaacagccg cccacgaaaaaaagcaaaaaattgtcctcaaatatcagcgaccttgacgtgctccggact gcctatgttctgctctgtacaaatccagatttatacagatcactctgggattggagttgt ttgacgcatattttgcaagagtcgcaaaagagcgaaacggtggaaaataatcccgtctta caatggatcgcatgtcactgtttggcacttgtttgtcgtttgagcccatcagatctggac aatctacttcgaaggcacattaaaaatgaagaagtatttattagcattcgacagaatgag tttcattcgtcaattgagacgaaaacccgcttaagctttgagccaatttcgtcgctgggt gagaggagatgtcatactattaatgtggagggtataacgcttatgaaaaagtggcagcca gatacaaaggaaaaccagtcacaaattcagcaaaaatcagatgtatctactttgccaagc atcgtacggacgccttcaatttgctccgcgctccgtgaaactgcatctgctatagtgtct ttgcgtcctgttctcatcacgggctcaattggtgtgggtaaaacccttcttgtggaagag ttggctcgtatgacaggcaacagattagtcaaagtacagcttggaaaccacgccgatagc aagatgctggtgggctcctactgctgcacggatattccggggaagttctgttggcaaccc ggtctggtttaccaggcagtgaccaatgggcagtggcttcttctggaggatctcgacttt gctccagtcgacattgtgaccttactaatgcctcttattcaggagcggagactccctgga gtaaatctggatggtggcctgacagctgcaagtggatttcgtcttttcacgacgatgcgg ctactgggaggggataaagcccacgggagagttcaacaccagggccattcagaaatggtc ggctcctgccaagccattgagggcttattgaccaaggttcacgtgtcgtctccaaatgat gcagagctagaacagatattgggtagtcatgcaccgattctacaaccttttcttcccaaa attatccatctttaccgtcgactacaaacacggctacaagaggaaggtcactgtaaacga gtgatatccctcagagatctcgttaagctggctaagagattagcagaaaatttccgtttg gattgctctaatcctgaagaattgtttttggatgctgtagattgcctaatcgaatttata gactctccctccttgaaattatcgttggctcaggcatacttaggtcccatattcaatatg gggccaaatgatgtgaagcatattgttgagcagcggaagcctaacgtgcagttggacgaa aaatccatcactgtcggacgttgctctgtcagtaagagaccgctaatgactgccatggaa aagttgcagttgcaggaatatgggaccacgggtgataagtttgccccaactcgtgtgtcc cttaacgtgcttgagaagatcatccgttgtatcacctgcaaggagcctgttcttcttgtt ggagaaactgggacaggcaagactacagtcgtgcaatatttagcccgccacacaaacaat cgcttgacggtgattaatttaaatcagcaaacagacattgtcgatctaatcggaggattt aagcccgttgcctcaacgttcactgtacttaactttattaatgaactgagggatctcctt aatgtacggaaaaaactactagaagggaatcgcagttttctagaaactcttatgatctcc tatgagcgaaaagctctggggaaggtatgtgccgcaatttcagagacgtgtaagcaaatg gcggacgctgtgaacgcaagcatcatacaaatcggtggcaactggcaagagaaacttaaa gatctcggaatgagggcgcatgccgttatgacacaacttgcgagcgacaagctagggaac gaacggatgtcattcgcatttattgagggttctttagtgaaggccatgcgtcgcggggac tggatcctgctagacgagatcaaccttgccgagactgagatgctcgaatgtttagcttct attcttgaatatggccaacttcttctacaggagaagggagaagctgatccagtacaatgt cacccgaattttcgaatattcgcatgcatgaatccggccacagatgtcggaaagaaagat ctaccagttggtatccgtaaccgtttcacagagctctactttgaagagatagttcaattt ccggaccttcaattggttgcccacagttatcttgggggagcatctccagtcgttgttggg caatgcgttgacctttacctgcgattgcgagagcttggccgtaccaaactcgccgatggc acaggacaccgaccacactacagcctgcgtacgctctgtcgggctacgcgttttgctggt cgaatgattcaggactgtcaacaagcagatcgggcaatctacgaaggattctgtttaagc ttcatcacacaaatggatcccgtttctcataagcttgtacagaatgaaatcaccagggct atcctgggccccaaggctgctagtcttcttggtgaacaactaaaacaaccatctggtggc aactttgtccagcttgaaggatactgggtaccttgtggtgacgaaaagcctcaaactcct gaagactacattttgactaacacagtacgagaaaacttgaaagatcttgctagagcagtc agcgcacgacagcatccggtgcttattcaaggagaaacgtccgtagggaaaacaagtctg atcacctatctagcgaaatgcacggggaataaatgcgttcgtgtcaacaatcatgaacat acggatattactgaatatatcggccaatatattgcggataagaacggggctctcgttttt aaggagggagtcttggtggaggcaatgcgtaaaggccactggatcattttagacgagctc aatcttgcgtgctctgaaattctcgaagcattaaatcgggtgcttgatgataatagaaaa ctcttcatatcggaatcacaaacagaggtcactgcccacccgaaatttatgctgtttgca acccaaaacccgccggggacatatgcgggtagaaaagtactttcacgagccttcagaaat cgtttcattgagctccactttaatgaacttccaccatcggagttggtaacgattctgtca aagcgttgtgcagtgtcgccgacccatgcaacgaaaatgattcgcgtcatgtcagaattg caactagagcgaaagggttcagggatctttgctggaaagcagggattcataacactccgg gatttattccggtgggcggaacgctatcgccgagttgaaagaactgggtttcacgattgg gaccagctgctcgccgatgaggggtacatgcttctagcgggacgagtccgacgtaatgaa gaagagcagattatttgtcgggcgctcaggaaggttttcaaacgtgaggtcgacagagac gcgttatggagcagctcagatacaacgaagtctgtacgggaaatgttagacaaatgggaa tgcgagactagtgcctgtgataaagacaactttgcccatgtggtttggacgaaaaacgcc cgccgtcttgccgttttagtcggacaagctctgaagtttggggagcccgtattgttggtt ggcgaaaccgggtgtggcaaaacaaccgtggttcagttgtttgcaagaatgcacggtcgt cgattgtactctgtaaactgtcatatgcactcggaggcggcagatttcattggaggtctt cggccatacagaggacgaacaagtaccgatgagttgtccaaagagaactatacggaaacg gagtctaacgatgactctggaaggttgtttgagtggaatgatggccccctcgtgaaagcc atgcaaagcggagatttctttctcgcggatgagatctcattggcagatgattccgttctg gagaggctcaactccttgcttgaaatcgagaagacgatcttcatagcagaaaaaggcgat ggcgtatgtatatcagctgccgcgaatttttggtttgcgtcaacgatgaaccccggtggg gattttggtaaaaaggagttatcacccgctctgcgaaatcggtttaccgaaatttggtgt ccttcgaatttgtgcgatgacgatctcctttgtgtgatccagcataaccttgcggaaaat gatagcgtcaatgaacaagccaagcagtggatagccaacggcatgatggaatttatgcgt tggtttgaacaggaagaatttggaaagaggaccgtaatatcgctgcgtgacatcctgtcg tgggtaaactttatcaacgtctatgcgcaccgtctaaatgcggagacagcgttcgttcac ggcgccgccatgatctttctggactctttgggcacaagaaacgcgtcagagcagggagac aacctcaaaacagctcgtactaaagcgcttggggtgctaatggcaagcatgcctaaccct gatttatgtttgctggaagatcaatgcctatcaattcgcgtgacggataagcatctcgca gtgggtccatataagttactcaaacatgcaggcgcccccacgcgtttactcgagttcaat ttttcggcgccgacaagctgcagcaatgcgatgcgtattttacgtgctatgggactccag aagcccctcctattagaaggagtgcctggcgttggaaagacaagtattgttattgcgctt gcaaaacaatgcggaaaacagataacgcggattaatctatcagaacaaacagatatcgct gatttattcggagccgatcttccggttgaaggaggtgtcggcggacgcttccgatggcgt gacggaccgctcttacgggcgttaaaacgaagtgattggatacttctcgatgaattgaat ttagcttcccaaagcgtacttgagggcctaaacgcttgtcttgaccatcgtggcgaaatc tttgtccctgagttaagtcggaccttcgctgttaagcgcggccaaacacgaatatttgga tgccaaaatcctcacaggcaaggctgtggacgaaaaggtcttccaaagtcgttccttaat cgcttcacccaggtgtacatggaacccctgaccgaagaggacttgtacctgattcttcgg cttctattcccatcattggatgccgggcagttgaagtccatggttcagttcaactctgtc ctatgtgacgaggtccaaacacgaggtttgtggggccacaatggtgcgccgtgggagttt aaccttagagacatgtgcagatgggcagatatggttatccgtcacaaaatgcggccgtcg gagctggtttcgttcgtttacgctgatcggatgagaagtgaggcagatcgccagaaagtg gctgacatatgtcaagtagtatttggcgaaaaaatggcccgaccttttcccaagctccgc ctcacgtcagactggctccaagttggtggatttttgctacagcgttcatacaatacagga tttgaatcactttcagaagatgttgccaatctgcgtttgctgcggagccaaaggagagta attgaaagcattgtcatgtgtcttaatcagggtacaatgtgtatactggtaggccctgcg ggttgcgggaaaacctcgtcagtaaagtcgctttgtgcccttctcggtcgcaaacttacg gttctacccgttacctcagaaatggatactattgagttactcggtggcttcgaacaggtt gatctaaaccgcgctctttcagaggtaatcaatagagcgattgaacaggttcgattgatg attgcttcacacctcaacgacaacagcttgggaaaggctgaagttttgctaaagggactg tactcactgagcaaagagtattccctctactgtagcggaactgagtcgacaaagacagaa aacccggttgacgcattcgttcaaaggattgctgtcgtgcgggcattcgtttctaggata cctctagcatcactgcttcctcagttgactcgcttggaggctctcgtcaaagaacacaaa tcgttgacatgcgggggccgctttacgtgggtcgattcacctttcgttcgtgcgctccag aatggcgactggttacttctggagaacgttaacttttgtgcggcttccgtccttgatcga ctgaactgtctactcgaaaaggacggggtcctaaccatctctgaagcaggagttcaagat ggcgaattacgaacgattgttcctcatcctgatttccgactgattctcactatggatcct agaaatggcgaaatctctagagcaatgcgtaatcgtggacacgaggtatatatgcttccc tttgatgacacaatagatgaatgggatttcgtatcattgttagaggccaaaggctgtttg gacgaagcactggctaaaaaatgttggtcaattgtgagcaacattcgacaccaaagcgtt tcgtacggcctggtgaaccagatggttcgtgcagtggacgcgatggaacaagagtcacgt tggggcactctgactattgccgcactcgccaaacttctcgtgcgttacattaaaccttta gtggctgattccgatattgaagtattagttcgatctcacctcagtggcatagagcacacc ataaagagtcgtcaaaggactgcttcggttcagaattatgttcatggaggcaacatggcg gaacattttgaagattcgattattttctcgcaaaagagaagccaaacggactcattcgag atgcaacaatttcgtaccggtatggtacaacagctttatttcgaaaacctagccttatcg gatattccagtgaaactaagcttcgttcacagtagcattgtcgtcgggattgtgatgacg ctgaccaacgagttttcccaacgccttagtaattacccaagagatctttgtattgactat cgattcaatccctgtttggccaagcagtttcaagcaaaaaatccatgggcaaacacattc gtatttgcacttatgaaagatgttctttacgcgcagctgcctttaaagtgcgatagtgaa atctgtgatacatacctaggcatcagtgcccgtcacaaggacaccctaccccacgtttta attggaatgctgccacacctcattgacactcttgaaggacttcttgaacaaaagaaatct ataaaaatgagtgaccaacagctggtggcagccaagcgtagcttatatggtgtatggcga tttaaacagaaagccaatcagccagtacggttcgtcgatcgagatatctctgtgatggct gtggttcttctatgggccttgaagaggctaataattttgtctgataccaatcgtgaagag aatgacaaaataataaaattagttcgacaactcgaaaggcttgtacctgatttgttcagc cgagctcgaaagttgcgcgaaactaccgttcgtgccgtgggtattccagctgtaatgaaa acccagagtcaggctgaactgttccaccgagctctatctattgagtttttaactaataac acgagtgaacgtgttgctactgaactggccgacgaggatgaggcagtcgttgcttgtgct attgaagaactggagcgaatgtctgcgcccatgaagcaagcagccaacgaaatcatagtc gatattgtggagaccgggtccgtattgcgaaagcaagaaatcgaagatattgaagacaag cttaagcaatttgtagagggcctgcagcgctttgataataactacgtcctaatcgcgcca tataaccatgatcaacgactgcacaagcatctgcggcctgtatatgaagtactagacatt cgaaggtcaatggccgcactcaatgcaagccatccagaattcatcccgaattttgtcgaa cttgcggtgcgcagttggagctgtatggctgaccttgatgtgcacctcaactggactccg ccacatatcatttcgacgctcaccacaggtgtaagatctgtcaagcaacgaatcatggac ggtaaaagaaagatgcattcgagcgcattggttttcaatcaccccgcgattacgcattgc ataggtccactagtagatgcagagaccaacaacgcaaaccttgaccttgattactcgcag atgaagctaagggaattagaagagattcgtcgtttattgtgggagtatgtcactgtagaa acaaagtttgctgatcaaaaccaaattgcaatgcaaaaaattgcatcagccattcgacct attctcgaagagaaccatgcatcgctaacagagggaatggttcatgcgcttttagccgta aaaaccgtagagcaagaaatcaaggcaaatccacaaaatgctaaacggaatattctcgtc caacaaatacgcgttgcccatcttttggtgcaaatctttacaccgttcgatgtaatggat ccgtacgagaaagttgctctgaaaaaggactacctcagtggagaagaaagtgtattggtt gatgaactcagaatacggcaatggcttcagatccgaagaacggcttgtgatactctggac caacatcccgcatacttaaacaacaccgttatttgtaaagccattaatgaaaaattgcaa aatctcgagaaacggactgcttaccgaccagagaagagccagtatccagagatagcacag gtaatgcagcagtacgtaaagcgcaacgccaacacagaaattgtggataaaatgttaaac tgtgtccttagtggtaaagatgcgacggcaacattcgatacttggttaattaatcaaaaa tctttcattttgacgatgcgtcgtgcttatccattctatcgagatattgtctacccgttc ctgtttggagcgagccagctggtgaactgctttgaggcactctacaaatttatacaaaac gatcagtctcaatctacggtaagcgaaattgttcaatttccgcgtgttgctgttattagt tcgcccttgttgaagaacattaccactttaatcctgaacgatgctgagaaaggaaacaca caagaaaacttgcagaaagtctggaaactaaagttccgtgagagcaaagctgacttactc gaagttcttgatgcgcttcggatgtcgtccggcgatcgtgagaaactaatcggcaaggtt gatcgtattgtgagttggttgactgctcaatacgctgaattcgccgctgccgaagcggaa cgcgagctcacgaaggactctttatatgaaatgagaaccaacgagtataagggtgaagaa aatgatgaggtacttcaggcgaaagcaattgccgctatgtttcccaactttgacgaggtc tacgaggatatcaccgatgatcgtgatttcttaaaccaggagaagcgtctcgaaaaatct accgagcatcaagacaacgaaagctcatcgttgggaaagttcagcgacgaagatctgctt atgatccatcgtattgttttagagattgtcagaacagccagtagcacagaaaggtcgagc cccgccgatattgtctcctgtttgctcgaacgttttcggctgttccaactgcttagtgat aacttcaaggattggttaaatatagaagttgatgatcaggcagttgctgcgcatctcatt gcctcggtgagcatgacttgggtaatctctggtaacgaggataagcttcattcgtacgcc aaaattgatagtcgaaccggtcaacaagtcgacttctatcgagatgcgaatattgccgag attattaaatgtcaaccggtcctccatcaaattatcagccgtactaaagaattgcttacc gaattcgaaactcaccacggcttagtgcaggttctaaaagtgagctatcgcgtattgagt ctgccgattacatctccactcatgaaagtactcgcaggcttggtacgcgtgctcacggaa atcgaggaatggaataagaatgttccgcgacatatgaaaatggcagcagaaatgacaagt ttggcccatttaattatctcatggagaaagttagaactatccagctggtctggtctacta gactctgctttggagaagcgaaaggttgaagcggccaagttttggctcaggcttgagcat gccgtctctgatcaacatgatgttgtcgtcgaggatgctgacgatgctcaacatactcgg caaaaagaggtggtaagaaccgctgtcacgctgatggaggccacaaccactttaggtgat ttcagctataagttggagatgttatcccagttagcctcttacgtaaaagcgcgcaaacga tcaggagacgacaaagtttatagtgcactgtctaacgtgcattcgtactatatgcaattt cttcctgttatcgaagaaaagatagagagcactcggagagcgatcaacaaggacataaac gactacatcaagattgtacgctacaaagacaccagctatcttgccatcaagcagtctgcc gagaaaagtcataaaaagctgcactattgtctgcgaaactttgagaaagttattcaggag cctgcaatttgctatttaaaacaacaaaatgatgccgattttgcttctgctccgataagg tcacggaaaaagaaaaaaatcacagagttgcgaagaattgatttggcgaatttttacgta aaagcagtagatcttaaggttccagcatcacataacgtagaatactcgaacattccattc tatcatcgcctggcacgtaaatatcttcgtgaagcatttgaagcatcgcatgtgcagtct attgcagacattcttgatgatgtggcgtccgatatcgctgaaaatatgagcaaattggca aaagagaccgagaaacagatacgccacgatgataaacaagcgaagaaaaaagccaaaagt ctgcttcaacgtaagaagaaaatgcttacaacgctgtttcgccaattaacgaaatgtgga ctatcttatcggaaaggtgtacttctataccaaaaggtcaaggcaatagatctcgtagcg acaccgttgctcgagtcgagtgaggtgcctgacgccgttcaagagtatgtcgacgatgtg aatgcatatttttttaaaagtgttcaaaaatatagcgaccttcagacggctatggagatg cctagtaaggagctcgaattgtatgttgtggaacgactgcaaggctttagtagccatctt ttcgaacagataaccagcgcaagtcatcatttgatcaaacttagtcgctatgcctttgag ctgcgcaaacacctcgtcaagctcaaggatgttgcagcctgtgagcgtatcccagagcaa gcgcataacgcaatgagaagaacggagatgctctcgctgctcctaaagctatgttcgtgt ctgcaacaatttgtcgtattgatagaaacgctaccaacaacggaaatggagacttcagtg aaagtgcttcaaactaaagagttagctcaaaagactagaacaaccctagttgaaaatatc accgctattcaagagcgcattcggctatttgaggcgatggatcctgcaccgctatctgaa agagaagtattagtccttgatgaaacggaaacggttcttaggggtatgcacttaaagctt aattttgtcatcagcagccttgaggctgggaaggccaattgcattacttcgccttactac gatcttctaaaagatatttctcggacactaaaagctactcagcggaggacgctggaagag gatgatgccaaggcagcactgcgctcagtagatgaggcgatgacgaaatgccttaagaaa gtacttctcacggttcagaatgtctttaaggcgtatgaacagacgcctgtgctggaccag gatgacaataccaccaatattcttaacatgcttgtcaacgagaaggtgaaacttcttgac aacttcgacttgcaaggagtacttcgaagcttcacaactttccaacagaagcttgtatgg ttgaacgtcgaaattccatcaaacaatcttagttctttcacggcgtttatggagaacttt tcgttgaatttcgagcatgcgtttgcttgtgctgttaaagctcaacgagcaaaattgaag ctcttgtacctagttctatgtgtgagtgttcagttgacgcagaaaggattttgcatcccc gaggaattccgcgatgatcttatgaaagaaggtgccacccagttgcaagatattgaggac ggcggcctcggagaaggtgaaggacaaaaagatacatctgacaaaattgactgcgaggac cagctcgaagaagcccaccaaaaagaacaaaagccccacgaaaaaaatgaagatgaaaac cagaaggacattgatgacgaaaaggagggcatcgaaatgagcgaagattttgatgcaaag gcccagggccctgatgagataaatatagaccaaaagaacgatgaagataaggacgaagaa caagacgaggatcagctcgatgatcagatgggtgacgtcgagaataataatccctttgat cttgataaaaagatgtgggataaagaacaggacgaagaaaatcaagatctcagttcagat gacgatgcccaaggtggggaagagttgcaggaagaaagtcagatggtggctaaagacgac aaagcaagagaaaccgaaaaagattcgaaaagcaaagatgaaaagccattcccagacgaa gatgacgaaaaccaaattaacgagatggatgacgagtacgaaggtgaaaaggaagaccca tacaaaagtggcaaacaggcgggtatggatgaggataacgaagttgaagatttccagttg cctgaaaacctaatagagacagaagaaatggaagaagaaggtagtgaaggtaaagacgac gcagatgacatcagtgatcgaggcaaggccgaaaacgatgaagacactgaagctcctgcc gatgaagagctatctgacttgccagaagaagttaatgagcctgtggacgatggcgaccct tcgaaggctgagcaagaagaagaaaaaatcgagaatcctgatagcattgaagacaaacgc gacgccagtgttgatgatgctttagataaaactgataaaaacgtgcctcagatcatacac gcaaagggcgatcgaagtgcagcgcaaaccgccgagcaacctgttgaccagcgaggggaa tgtatgcagactagcgaagatatagatggctcaggtgaaggtcaaagttcctccgcgaat acggaggatatgggcaatacgacggaccgcgctcgcgaggacgcgtcgcagactaagggt gcgtctcgggaaaagcaaaaaaaatcttcaaatgaacgcaagattgctttacaaatgcca caacataaggaccttatcaacggcaacatttcgcaagctgtcgaccacgagaagcagtcc ggtttagagaaaggaagcgaattcgaacatcaacacaaagatgacgaaaacgctgacatt gaagaggtggcagttgatatggctaccgatgaacaggctgaaaaaacccaaccggttgca gccaatgaaacagaacaggctgaatcggaaggtagcgattcgggcatggaggatattggt gtgaatgattccgaggacccaatgagtgtcgacgaccaggaggctaacgataagcgcaag gagcagacgtatcagcaacagcagcggactaaagataaggggaaaataccgaagttgccg aagagcgaaccaggcccagagggtgaagcgcagttcaagaatggggatcttgtacgtaca caaacagtgcagcgaggcaaccaggccgtcgtcgagacacgcactgatcttctatttgaa aaagttgaagcagtcaatctgggagttcaggctatatgcccagaagaattttcgtgtgat ttggccgaatgtagacgcgtatgggcagaagcagaaaagagtgtatctttattggtgcag gagctgtgtgagcagctccgtcttgtgctagagctgacgaaagcgtcgaagtttaaagga gactacagaagtggcaaaagattgaatatgagaaaggtaattgattacgtcgctagcgga ttccggaaggatagaatctggatgaaacgcacaaaacctaacaaacgccaataccaaatc ctgcttgctgtcgatgactccgcttcgatgtctgattcgaaagcaaaggaaatgactttt gaaacggttgcactccttgctaacgctctgaattttctcgaggctggagagttgtctgtt gcttctttcggagtaaacgttagcctcgttcatccgttaggtgaatcgtggatatcagac agtggtgctcatcttgtcagaagtttcaccttttcacagactgagacaagggtgtcaaac ctcatctctttcgcaacagacatgttcgaaaagagcagatccagtattaacggtaatcca gtacaaagagaaactgcccagcttttgatcatcgtatcagatggccgtcttatgtcagag ggcactgaattagttaaaggaacaatccgaagagctagagaaaacgggattttcattgtc taccttctcctggataatcccactgcgattcagggttccatcatggagatgcaaagggct tctttcgatgccactacacaacaaccgattctttgtcgatatatggaatcatttccgttt cctttctacgtagtcctccgtgagcttgactcgatgccggttgtgctcggagaagctctc cgacaatggttcgaacttgtcactggaaagtag

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