Vibrio sp. EJY3: VEJY3_02230
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Entry
VEJY3_02230 CDS
T01683
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vej
Vibrio sp. EJY3
Pathway
vej00260
Glycine, serine and threonine metabolism
vej00261
Monobactam biosynthesis
vej00270
Cysteine and methionine metabolism
vej00300
Lysine biosynthesis
vej01100
Metabolic pathways
vej01110
Biosynthesis of secondary metabolites
vej01120
Microbial metabolism in diverse environments
vej01230
Biosynthesis of amino acids
Module
vej_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vej_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vej_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vej00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VEJY3_02230 (thrA)
00270 Cysteine and methionine metabolism
VEJY3_02230 (thrA)
00300 Lysine biosynthesis
VEJY3_02230 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VEJY3_02230 (thrA)
Enzymes [BR:
vej01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VEJY3_02230 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VEJY3_02230 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Alba
Motif
Other DBs
NCBI-ProteinID:
AEX20944
LinkDB
All DBs
Position
1:497577..500036
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AA seq
819 aa
AA seq
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MRVLKFGGSSLADADRFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIEGALRNGEA
ELQINELEESFKTLFADIQALVPNLDGTGYDNQVKTSLSQLRQFVHGISLLGMCPNNVNA
RIISKGERVSIQLMKAVLEAKGQKASLIDPVEYLYAQGDHLEAMVDVDISTQNFRQKPLP
QGHVNIMPGFTAGNEKGELVTLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
EDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLNDLTMVNVSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIEAEDKAKAQQTLAEAFELELKDGLLEPVEFIDDVAIVTLVGDGMRTSRGVASRFFSSL
AEVNVNIVAIAQGSSERAISAVIPEDKISEAIKACHMNLFNSKHFLDVFVVGIGGVGGEL
VDQIERQQAKLAEKGIIIRVCGLANSKGLLLDSEGLPLEHWRDRMSSATEEFSLARLIAL
VQRNHIINPVLVDCTSSEAIANQYADFLAAGFHVVTPNKKANTASMAYYHQLRDVARSSR
RKLMYETTVGAGLPVIENLQNLISAGDELERFTGILSGSLSYIFGKLDEGMSLSEATNIA
KENGFTEPDPRDDLSGMDVARKLLILAREAGMSLELEDVVVDQALPPGFDDSGSVDEFMA
RLPEADAYFKDLVEKAAEEGKVLRYVGEINDGKCKVSIAIVDENDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattgaagtttggcggttcatcattggctgatgcagatcgctttttaagagca
gcagatatcattgcgaataatgctcaacaggaagaagtcgcagtcgtgctttctgcaccg
ggtaaaacaactaataaactggttgctgtgattgaaggcgctttacgaaatggtgaagca
gaattacaaattaacgagttagaagaatcgtttaaaacgctttttgccgatatccaagcc
ttggttcctaatctggatgggactggctacgacaatcaagttaaaacctcgctctctcaa
ttacgtcaatttgtccatggcatcagcctgttaggcatgtgtccaaacaatgtgaatgcg
cgcatcatcagtaaaggtgaacgtgtttctattcaactaatgaaagcggtacttgaagca
aaaggtcaaaaagccagcctaattgatccggttgaatacctttatgctcaaggcgatcat
cttgaagcgatggttgatgttgatatttctacacaaaacttccgccaaaagcctcttcct
caaggtcatgtcaacatcatgcctggttttactgccggcaacgagaaaggagaactggtt
actctaggtcgtaacggttctgactattcggctgcggttttggctgcttgtcttcgtgcc
gactgttgtgaaatctggactgacgttgatggcgtatacaactgtgatcctcgcttggta
gaagatgcacgactattaaaatcactgagctatcaggaagcgatggagttgtcttacttt
ggtgcgtccgttctgcaccctaaaaccatcgctccaattgctcaattccacattccatgc
ttaatcaagaacagttttaacccgcaaggtgcaggtacgctgattggccaagataccggt
gaagataacctcgctatcaagggtattactacactgaatgacctgaccatggtgaacgtc
tctggcccaggtatgaaaggcatggttggcatggcaagccgcgtatttggtgctatgtct
tcagcgggtgtttcaatcgtactgatcactcagtcatcatcagaatacagcatcagcttc
tgtatcgaagcagaagacaaagcaaaagcgcaacagactctggcagaagcatttgagctt
gaactgaaagacggtctgcttgaaccagtagagtttatcgatgatgttgctatcgtgacc
cttgttggtgacggcatgcgtacgtcacgcggcgttgcgtcacgtttcttctcatctctt
gctgaagtaaacgtcaacattgttgcgatcgcacagggttcttctgagcgcgctatctca
gcggttatcccagaagataagatctctgaagcaatcaaagcctgtcatatgaacctgttc
aattctaaacacttccttgatgttttcgttgttggtatcggtggtgttggtggtgagctg
gtggatcagattgaacgccaacaagccaaactggcagagaaaggcatcatcattcgcgta
tgtggtctggcaaacagtaagggtctgcttctggatagtgaagggctgccactggaacat
tggcgcgaccgcatgtcttcagctactgaagagttcagcctagcgcgcctgattgcactt
gtgcaacgtaaccacatcattaaccctgttttggttgattgtacttcgagtgaagccatt
gctaaccagtacgctgatttcttggcggcaggtttccacgttgttactccaaataagaaa
gctaataccgcaagtatggcttactaccaccagcttcgtgatgtagcacgcagctctcgt
cgtaaattgatgtacgagacaacggttggtgcgggtttgccggtcatcgaaaacctgcag
aatcttatttcagcgggtgatgagcttgaacgattcaccggtattttgtctggttcacta
tcttacatcttcggtaagctagacgaaggcatgagcttgagcgaagcgacaaacatagcg
aaagaaaacggcttcaccgaaccggatcctcgtgatgatctatcgggtatggatgtggct
cgtaagcttcttattctggcgcgtgaagcgggaatgtcgcttgagttggaagacgttgtg
gttgatcaagcgctgccaccgggctttgatgattcaggcagtgttgatgagtttatggcg
agacttcctgaagctgatgcgtactttaaagatcttgtcgaaaaagccgctgaagagggt
aaagttttacgctatgttggtgaaatcaatgatggtaagtgcaaagtcagcattgctatc
gttgatgaaaatgatccaatgttcaaaattaaagatggtgagaacgctctggcgttttac
agccgttactaccaaccaatcccattggtacttcgtggttacggtgcaggtacggaagtt
accgcagcaggcgtattttcagatgtgatgcgtactttaggttggaaactaggggtataa
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