Vibrio europaeus: IXK98_21420
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Entry
IXK98_21420 CDS
T07114
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
veu
Vibrio europaeus
Pathway
veu00260
Glycine, serine and threonine metabolism
veu00261
Monobactam biosynthesis
veu00270
Cysteine and methionine metabolism
veu00300
Lysine biosynthesis
veu01100
Metabolic pathways
veu01110
Biosynthesis of secondary metabolites
veu01120
Microbial metabolism in diverse environments
veu01230
Biosynthesis of amino acids
Module
veu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
veu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
veu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
veu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IXK98_21420 (thrA)
00270 Cysteine and methionine metabolism
IXK98_21420 (thrA)
00300 Lysine biosynthesis
IXK98_21420 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IXK98_21420 (thrA)
Enzymes [BR:
veu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IXK98_21420 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IXK98_21420 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QPG35993
LinkDB
All DBs
Position
1:complement(2773454..2775913)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADADRFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVSVIEGALKNGEA
ELQIAELEDSFRDLFQDIKQVLPNIDGSGYDNQVKTSLTQLRQFVHGINLLGMCPDNVNA
RIISKGERVSIQLMKAVLEAKGQAASLIDPVQYLFARGEYLEAMVDVEVSTQNFRQNPLP
QGHVNIMPGFTAGNEDGELVTLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLSDLTMVNVSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIEAQDKDIAEQALSETFELELKDGLLEPVEFISDVAIVTLVGDGMRTSRGVASQFFSSL
AEVNVNIVAIAQGSSERAISAVIPEDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQAKLAEKGIVLRVCGLANSKGLLLDSEGLPLDHWRDRMKDASEEFTLARLISL
VQRNHIINPVLVDCTSSESIANQYADFLAAGFHVVTPNKKANTSSMAYYHQLRDVARSSR
RKLMYETTVGAGLPVIENLQNLISAGDELERFSGILSGSLSYIFGKLDEGMTLSQATNIA
KDNGFTEPDPRDDLSGMDVARKLLILAREAGMNLELEDVIVDQALPPGFDDSGSVEEFMA
RLPEADAYFKQQSAQAAEEGKVLRYVGEISDGQCRVSIAAVDENDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttttaaagtttggaggttcatcattagcggatgctgatcgttttttaagagcg
gcagatatcattgctaataatgcccagcaagaagaagtggcggttgtgctttcagcaccg
ggaaaaaccaccaacaagttagtttctgtgattgaaggcgcgttaaaaaatggtgaggct
gagctacaaattgctgagctcgaagattctttccgcgaccttttccaagatatcaaacaa
gtgctgccaaatattgatggcagtggttacgacaaccaagttaaaacttctctaacccag
ttacgtcaattcgttcatggcatcaaccttttaggcatgtgcccagacaacgttaatgca
cgcattatcagtaaaggagagcgcgtttctatccaactaatgaaggcggtattagaagcg
aaagggcaagcggcaagtctgattgatcctgttcagtatctatttgctcgcggtgagtat
ttagaagcgatggttgatgttgaagtttcaacgcaaaacttccgccaaaaccctcttcct
caaggtcacgtcaatatcatgcctggttttactgcgggtaatgaagatggcgagttggtc
acgctaggtcgaaacggctcagattactcagcggcagtattggctgcgtgtctacgcgcg
gattgctgtgagatttggactgacgtagatggtgtctacaactgtgaccctcgcctagta
gatgatgcgcgtctacttaaatcgctcagttatcaagaagcaatggaactttcttacttt
ggtgcttccgttctgcaccctaaaaccattgcgcctatcgctcagttccacattccttgt
ttaattaaaaacagctttaacccacaaggagcggggactttaatcggtcaagatacaggt
gaagacaacctcgctattaaagggatcacgacgcttagcgacctaacaatggttaacgtg
tctggcccaggtatgaaaggcatggttggcatggcgagccgagtgttcggggcaatgtct
tcagcaggtgtctctattgtgctgattactcagtcttcttctgaatacagcatcagtttc
tgtattgaagcacaagacaaagacattgctgagcaagcactgagcgagactttcgagctt
gagctgaaagacggtctactagagcctgtcgaatttatcagtgacgtggctatcgtaacg
ctagtgggtgacggcatgcgcacatcacgtggtgtggcttcgcaattcttctcttctcta
gctgaagtaaacgtcaacattgtcgctatcgcacaaggttcttcggagcgtgctatttca
gcggtgattccggaagataagatctctgaagcgatcaaagcgtgtcatgagaatctattt
aactcgaaacacttccttgatgtctttgtggttggtgttggcggtgtcggtggtgaactg
gtggatcagattcagcgtcagcaagctaaattggcagaaaaaggcattgtccttcgagta
tgtggcctagcaaacagcaaagggctattgctagatagtgaagggttacctctcgatcat
tggcgtgatcgcatgaaagatgcttccgaagaatttacattggcgcgcctgatttctctt
gttcagcgtaaccacattatcaaccctgtgctggtggattgtacttcgagtgaatctatc
gccaatcaatatgccgatttcttagccgctggcttccacgttgtcacaccaaacaagaaa
gccaatacgtcaagcatggcttactaccatcaacttcgcgatgttgctcgtagttcacgc
cgtaaactaatgtacgaaacaacggtcggtgctggtctgcctgttatcgaaaacctacag
aaccttatttctgcgggtgatgaacttgaacgctttagcggcatcttgtctggttcactc
tcttatattttcggtaagcttgatgaaggtatgacgctaagccaagccaccaacattgcc
aaagacaatggctttacagagcctgacccacgtgacgacctttcaggtatggatgtagcg
cgtaagctacttattcttgcacgtgaagctggtatgaaccttgagcttgaagatgtgatc
gtcgatcaagctctgccacctggctttgatgattcaggcagcgtagaagagtttatggct
cgtcttccagaagcggacgcttactttaaacagcaatctgctcaagctgccgaagagggc
aaagtactgcgttatgtgggtgaaatttcagatggccaatgccgagtaagcattgccgca
gtagatgaaaacgatccaatgtttaagattaaagatggtgagaacgcactggcattctac
agccgctactaccaaccaattccgcttgtattacgcggttacggtgcgggtactgaagta
acagcggcaggcgttttctcagacgtgatgcgtacattaggttggaagctaggagtttaa
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