Aliivibrio fischeri ES114: VF_2118
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Entry
VF_2118 CDS
T00236
Symbol
thrA
Name
(GenBank) fused aspartokinase I and homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vfi
Aliivibrio fischeri ES114
Pathway
vfi00260
Glycine, serine and threonine metabolism
vfi00261
Monobactam biosynthesis
vfi00270
Cysteine and methionine metabolism
vfi00300
Lysine biosynthesis
vfi01100
Metabolic pathways
vfi01110
Biosynthesis of secondary metabolites
vfi01120
Microbial metabolism in diverse environments
vfi01230
Biosynthesis of amino acids
Module
vfi_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vfi_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vfi_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vfi00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VF_2118 (thrA)
00270 Cysteine and methionine metabolism
VF_2118 (thrA)
00300 Lysine biosynthesis
VF_2118 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VF_2118 (thrA)
Enzymes [BR:
vfi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VF_2118 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VF_2118 (thrA)
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Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AAW86613
UniProt:
Q5E2Y3
LinkDB
All DBs
Position
I:complement(2352651..2355110)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADSDRFLRAADIIANNAQQQEVSVVLSAPGKVTNKLVSVVDNLLTNGEA
ELQISELESVFTQLFSGISNTLPQVDLKLLENKLKDSISQLRQYAHGITLLGMCPDNVYA
KIISKGERISIVMMKAVLEAKGQPASLIDPVKYLYAKGDYLEGAVDVDVSTLNFKNEPLP
QGHVNIMPGFTAGNAKGELVTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLNNLTMVNVSGPGMKGMVGMASRVFGAMSATGISIVLITQSSSEYSISF
CIEAEDKCKAEQVLREAFELELKDGLLEPVEFTDNVAIVTLVGDGMRTSKGVASQFFTSL
TEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIKRQQPKLAEKGIEIRVCGLANSRGLLLDSKGIPLEDWRERMSNSSEEFSLARLIAL
VQRNHIINPVIVDCTSDHGIAAQYVDFLSAGFHVITPNKKANTDSMAYYHQLRNAARGTR
RKFMYETTVGAGLPVIENLQNLIAAGDELEKFNGILSGSLSYIFGKLDEGMSLSEATNVA
KENGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTVEEFMA
RLPEADAYFAEQSAIAAEDGKVLRYVGEILDGKCKVRIVAVDGDDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFSDLMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattaaaatttggtggttcgtcattagctgattcagatcgttttttacgtgcc
gcagacattattgctaataatgcacagcaacaagaagtttctgtcgtattatcagcgcct
ggaaaagtaacaaataaattagtttcagtggttgataatcttcttaccaatggtgaagca
gaattacaaatctcagaactagaatctgtttttactcaattatttagtggtatttctaac
acccttccacaagttgatcttaaattacttgaaaataagctgaaagattctatttctcaa
ttacgtcaatatgctcatgggatcaccttgcttggtatgtgtcctgataatgtatatgca
aaaatcatcagtaaaggtgaacgcatttctattgtcatgatgaaagccgtattagaagca
aaaggtcaaccagcaagcttaattgatcctgttaagtatttatatgcgaaaggcgattac
cttgaaggtgcggtagatgttgatgtatcaacattaaactttaagaatgaaccattgccg
caaggtcatgtaaatattatgcctggctttactgctggtaatgcgaaaggagagttggta
actcttggccgtaatggttctgattattcagcagcagtacttgcagcatgtttacgagct
gaatgttgtgaaatttggactgatgtagatggtgtttataattgtgacccacgtttagtt
gatgatgctcgtctattaaaatcattaagttatcaagaagctatggagctctcttacttt
ggtgcttctgttcttcacccgaaaaccatcgctcctattgctcaattccacattccttgt
ctaattaaaaatagctttaaccctcaaggtgcagggactctaatcggtcaagataccggt
gaagataatctggctattaaagggattacgaccctaaataacttaaccatggttaatgtt
agtgggccgggtatgaaaggcatggttggtatggcaagtcgtgtatttggtgctatgtcg
gcaacagggatctcaattgttctcattactcaatcctcatcagaatacagtataagtttt
tgtattgaagctgaagacaaatgcaaggcagagcaagtactaagagaagcgtttgaatta
gaacttaaagatggcttattagagccggttgagtttacagataatgttgccattgttact
ttggttggcgatggcatgcgtacatcgaaaggcgtagcatctcaattctttacttctctt
actgaagttaatgtgaatattattgccatcgcgcaaggatcttctgagcgtgcgatttct
gctgttattcctgaagataaagtatctgagtcgataaaagcatgtcatgaaaacctattc
aatagtaaacatttcttagatgtatttgttgttggtgttggtggtgttggtggtgaatta
gttgatcaaatcaaacgccagcaaccaaaattggcagagaaaggcattgaaattcgagta
tgtggtttggcaaatagccgaggattactactggatagcaaaggcattccgctagaagat
tggcgtgagcgtatgagtaattcctctgaggagttcagcttagctcgtttaattgctttg
gttcaacgtaaccatattattaacccagttattgttgattgtacgtctgaccatggtatc
gctgctcaatacgttgatttcctatcagctggttttcacgttattacaccaaataagaaa
gccaatacggattcaatggcttattaccatcagttacgtaatgctgcgcgtggtactcgt
cgtaaatttatgtatgaaacaacggttggtgctggcttacctgttatcgaaaacttacag
aacttgattgcagcaggtgatgagcttgaaaagttcaacggtatcttgtctggctctctt
tcttatatctttggtaagttagatgaaggtatgtcattaagcgaagcgacaaacgtagcg
aaagaaaatggctttacagaaccagatcctcgagatgatctttcaggtatggatgttgct
cgtaaattattaattctagctcgtgaatcaggattagaaattgagctagatgatgtagaa
gttgagcaagcattaccgccgggctttgacgattcaggtacggttgaagagtttatggct
cgacttcctgaagcggatgcctattttgctgagcaatcggctattgcagcagaagatggc
aaggtattacgctatgttggtgagatcttagatggtaaatgtaaagtaagaattgttgct
gtagatggcgatgatcctatgtttaagattaaagatggcgagaacgcattggctttctat
agccgctattatcaacctattccattagtattgcgtggttatggcgcaggaaccgaagta
accgctgctggtgtgttctctgatttaatgcgtacgcttggttggaaattaggagtatag
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