Virgibacillus sp. SK37: X953_12385
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Entry
X953_12385 CDS
T03219
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
vir
Virgibacillus sp. SK37
Pathway
vir00300
Lysine biosynthesis
vir00550
Peptidoglycan biosynthesis
vir01100
Metabolic pathways
vir01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
vir00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
X953_12385
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
X953_12385
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
X953_12385
Enzymes [BR:
vir01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
X953_12385
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AIF43846
UniProt:
A0A075JP80
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Position
complement(2274429..2275793)
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AA seq
454 aa
AA seq
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MLFTIDWLAGFLPNFKKQREEETIINEVVTDSRIKVSKSLFIPLVGENFDGHEYVHQAVE
NGAVAILWTKDRKLPQSFPNDISVFFVDDTLIALQQISSEYRKEVNPVVIGITGSNGKTT
TKDLVAAVMGTTYNTHATKGNLNNHIGVPLTILSMKRDTEVLILEMGMSNFGEIDRLSTI
AIPDYVVITNIGESHIEYLGSRKGISEAKMEILNGLKEEGLAVIDGDEPLLKHLHSNKNV
RTCGYDSTNTSVIEKCVVGHGQTNFHLSDGNSYSIPLLGKHHAKNASFAILLAKEMKIPT
AEIKKGLNSLEQTSMRFQLVQGINGVSVINDAYNASPTSMIASIEVMKQMEGYGERILVL
GDVLELGDYSEELHRSIAHEIKHPITVLYTFGIEAKYIYDEVSRMSSEIKIEHFSSKEDL
VRDLEPFLNDETIILVKASRGLKFETIVNKLIKK
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgttatttactatagattggttggcaggatttttgcccaacttcaaaaaacagcgtgaa
gaggaaactataatcaatgaagttgtgacagacagtcgaattaaagtaagtaaatcactg
tttattccattggttggcgagaacttcgacgggcatgaatacgttcatcaagcagttgaa
aatggggctgtagctattttatggacgaaggacaggaaactacctcaatcgtttcctaac
gatatatcagtattttttgtggatgatacattaatagctctccagcaaatctcttcagaa
tacagaaaagaagtaaatcctgtcgttataggaattacagggtctaatggaaaaacaact
acaaaagatttggtagctgctgttatgggaaccacctataatacacatgcgacaaaagga
aatttaaataatcatattggtgttcctttgactattctttccatgaagagagatactgaa
gtccttatccttgagatgggtatgagtaattttggagagatagacagattgtctacgatt
gcaattcctgattatgttgtgatcacaaatattggtgaatcacatattgagtatttaggg
tcacgcaaaggtatttctgaagcgaaaatggagattttaaatgggttgaaagaagaaggt
ttagctgtaattgacggagacgaacctcttttaaaacacctacatagtaataagaatgta
cgtacttgtggctatgattccactaacacaagtgtaattgaaaaatgtgtagttggccat
ggtcaaaccaattttcatttatctgatggcaactcctactccatacctttattgggaaag
catcatgctaagaatgcttcttttgctatcctgctggcaaaggaaatgaagattcccact
gcagaaataaagaaaggtttgaattcattagagcaaacctctatgcgtttccaattagta
caggggataaacggtgtttctgttattaatgatgcctataatgcctctcctacctctatg
atcgcttcaattgaagttatgaaacaaatggaaggctatggcgaacgaatattggtgttg
ggagatgtattagaattaggtgattattcagaggaactacaccgttctattgcacatgaa
attaaacatcctattactgtgttatatactttcgggatagaagcaaaatatatctatgat
gaagttagccggatgtcttccgaaattaagatagagcatttttcttccaaggaagattta
gtaagggacctagaaccgtttttaaatgatgaaaccattattttggttaaggcttccaga
ggtttgaagtttgaaactattgtaaacaaattaataaaaaaataa
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