KEGG   Varanus komodoensis (Komodo dragon): 123018488
Entry
123018488         CDS       T07701                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
vko  Varanus komodoensis (Komodo dragon)
Pathway
vko00562  Inositol phosphate metabolism
vko01100  Metabolic pathways
vko04020  Calcium signaling pathway
vko04070  Phosphatidylinositol signaling system
Module
vko_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:vko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    123018488 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    123018488 (PLCE1)
   04070 Phosphatidylinositol signaling system
    123018488 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vko04131]
    123018488 (PLCE1)
Enzymes [BR:vko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     123018488 (PLCE1)
Membrane trafficking [BR:vko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    123018488 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    123018488 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 123018488
NCBI-ProteinID: XP_044276579
Ensembl: ENSVKKG00000000663
LinkDB
Position
Unknown
AA seq 2189 aa
MTLCRKAAKGMLYNHFYKSCDSFTKKDKCLETGISSSLEKAMHAEIQLKMDGSQVELKPL
RSQSSVNENETESVDFSYVKNRNISKGLCTLHDRLIWNDSLQSVKTYNESTSDSTICTCK
LIELPTTCGDKTGQQLCDSYDTSVHNYLCLERASQKLSVACLSHNTFSSGNFTGRIYSKP
ILSHFENCNESYREEMEEDLSRSKKERSTLLIRRFCKNDKEVKKSVYTGTRAIVRTLPSG
HIGDTAWNYVDHWRTNCRIISEQLTLQVSISHTLNPYLLQSIWHEILKSAQGTEDSLEYF
PHPLREPLTSYHHANCWCKENSSCIKPSIQRAPKYRATLHRTSLSNFISGALLEATTSLG
ARNGALNIFGGSTGKNMLKERQLSSSMAGSNALTSTVAGMSKELVELQHLIQFPEEVASI
LTEQEQDLYRKVLPIDYLCFLTRNMGNAECQSKLSTIKTSISATLLSAPNGECSAVEDLV
TRFNEVSSWVTWLILTAGSMEEKREVFSYVVHVAKCCWNMGNYNAVMEFLAGLRSRKVLK
MWQFMDQSDIEMMRSLKDAMAQHESSSEYRKVVNRALNIPGCKVVPFCGVFLKELCEVLD
GASSLIRLCPQYNSQDETLEFVAEYNGQDNYLQRIGQDGLHNIEKESTANYIFQTIRSCN
RSLETEDGEDNFIEYEDRNSRRNSLKDKNRYQLITGELSDSESDIFEQSKEWTTQLAEEQ
QKAFSHGIELIPWYVLSVRADVHQFMLQGATVIHYDQETHFSVRCFLQLQPDNSTLTWMK
STTVCSASSKMKLNMPGSTAELGKFQFLGNTGLNGLVEGCLDLFSAKAVYMGHSGIDMHA
VCIQHKLCNMSLEENGITLLYGLQTTENKLLHFVAPKYTAKMLFDGLLELMNAVRKMKKF
PDQRLQWLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNTSPGNLIKSVEKPGVQR
NNTLGIVTAKKKKKVLMRGESGDGTDDEMTTRKARPFKENRSRSGSDPQDIDEQDEIEPS
LLVAFSGTSTLPSRRTQSLTTSVPPSVTPGVSSPVRPVSSPVMPSSVKGQSSAWSSSSWH
GRVKGGLKGFQTCMVSDSNMSFVEFIELFKSFSVRSRKDLKDLFDVYTIPCNRLSAESVP
LYTSLKIDENTNGLQPDLDLLTRNISDLGLFIKSRQQLSDNQRQISDAIAAASIVTNGTG
VESTSLGIFGVGIQQLNDFLVNCQGEHYTYDEILSIIQKFEPSINMCQQGLMSFEGFARF
LMDKDNFASVNNESQENTEDLLFPLSYYYIESSHNTYLTGHQLKGESSVELYSQILLQGC
RSVELDCWDGDDGMPVIYHGHTLTTKISFKEVVEAIDRNAFVTSDMPIIISIENHCSLPQ
QRKMSEIFKNTFGEKLVTKFLFESDFSDDPMLPSPHQLRRKVLLKNKKLKAHQTPVDILK
QKAHQLAYMQAQASNGGNLGNLTTTNEEEEDEEDEYDYDYESLSDDNILEDRPENKLTID
KLQFEYSEETAKRIKKMDSTAYNSKGKVYDMELGEEFYLSQNKKESRQIAPELSDLVIYC
QAVKFPGLSTLNPSGSSRGKERKSRKSIFGNNPGRLSPGEPAMLAKASGKGAFDSARQTW
EEACSPAFSPTASLSSIIRTPRCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRTYPAA
TRIDSSNPHPLLFWLHGVQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCP
MYQHFCPLERELDNMEPAIYSLTIVSGQNVCPGNSTGSPCIEVDVLGMPLDSCHFRTKPI
HRNTLNPMWNEQFLFRIHFEDLVFLRFAVVENNSSAVMAQRIIPLKALKRGYRHLQLRSL
HNEVLEISSLFINSRRMEENPSGNALSATSQFSTAERRAAAMYKVTVCGIPGPEPFTLFT
VKQGTTVAQLLYQIFTTTKGIGKYPADYFLMEEKCFISKERNEYSKPPFQRVLGPEEELV
QLLNSWFPEEGYVGRIIFKTREENLNRRNFFQEEKDEAVTVSEDDSFFVQVHDVSPEQPR
TVIKAPRFSTAQDVIQQTLCKAKYSYSILNNPNPSDYVLLEEVTKEQANKKSSTAKTSQR
ILSDQECVFQAQNRWKGAGKFILKLKEQVQAGRDDKKKGISLANELKKLTKSSKQYRGFI
TPPLQTSSDGLQNKDDKTTCSLTFSDTVE
NT seq 6570 nt   +upstreamnt  +downstreamnt
atgacattatgcagaaaagctgcaaaaggaatgctttacaaccacttttataaatcgtgt
gattcttttacaaagaaagacaaatgtttggaaactggaatatcttcttcactggaaaaa
gccatgcatgctgaaattcagttaaaaatggatggatctcaagtagagttgaaaccacta
agaagccagtcctcagtaaatgaaaatgaaactgagagtgttgatttcagttatgttaaa
aatagaaacatctcaaaaggtttatgtaccttgcacgacagattaatttggaatgactcc
ttacaatcagtaaagacttataatgaaagcaccagtgattccacaatctgcacttgtaaa
ttgatagaactaccaactacctgtggggataaaactggacaacagctatgtgattcctat
gatacttcagtgcataactatttgtgtttggaaagagcatcccaaaaactcagtgtggca
tgcttaagccacaatactttctcaagtggtaattttactggaagaatatattcaaagccc
attctgagccattttgaaaactgcaatgaaagctatagagaagagatggaggaagatctt
tcccgaagtaagaaggagcgctcaactttattaatcagaagattttgcaaaaatgataag
gaggttaaaaaatcggtctatactgggacaagagcaattgtaaggactttaccatctggg
cacataggagatactgcttggaattatgttgaccactggagaacaaactgtaggattata
tcagaacagttaacacttcaagtttcaataagtcatacattaaatccctaccttctgcaa
tctatatggcatgagatcttgaagtcagcacaaggaacagaagattctttggagtatttt
cctcaccctttgagggaaccgctaacatcataccatcatgcaaattgctggtgcaaagag
aactcctcttgcataaaaccatctattcaaagagctcccaaataccgtgccactctacac
aggacatccctttcaaattttatcagtggtgctttgctagaagcaactacatcattagga
gcaaggaatggtgcactaaatatattcggaggatcaactggaaagaacatgctaaaagaa
cgacagttgagttcatctatggctggatcaaatgcccttacttccactgtagctggtatg
agtaaagagcttgtagaacttcagcatctcattcaatttccagaggaggttgctagtata
ctgactgagcaggagcaggatctctaccggaaagtattgcccattgactacctctgcttc
ttaactagaaatatgggaaatgctgaatgccagagcaaactttcaactattaaaacttca
atttctgcaactcttctttctgccccaaatggggaatgcagtgctgttgaagacctggtg
acaagattcaatgaggtgagctcttgggtgacatggctgattctgactgcgggttctatg
gaggaaaaacgagaagtcttctcctatgtggtacatgtggcaaaatgctgctggaacatg
ggaaactacaatgctgttatggagttcttggcagggctcaggtcaagaaaagttttaaaa
atgtggcagttcatggaccaatctgatattgaaatgatgcgaagcttgaaagatgctatg
gcacaacatgaatcttcatcagaatatagaaaagttgtaaatcgagctctgaatatccca
ggctgtaaagttgttcctttctgtggtgtatttttaaaagaactctgtgaagttttggat
ggggcttcaagtctcatcagactttgtcctcagtataactcacaagatgaaacactggag
tttgttgcagagtacaatgggcaagataactatttacaacggataggtcaagatggccta
cataatatagaaaaagaatcaacagctaactacatttttcaaactattcggagctgtaat
cgcagcttggaaacagaagatggagaagataattttattgaatatgaagacagaaattcc
agaagaaattctttgaaggacaaaaatcgttatcagcttataactggagaactgtcagat
tctgaaagtgacatatttgaacagtctaaagaatggactacacagttagctgaagagcag
cagaaagctttcagtcatggaatagagctcattccctggtatgtgctgtcagtcagagct
gatgtccatcagttcatgcttcaaggtgcaacagttatacattatgaccaagagacacac
ttttcagtacgctgtttcctgcaacttcaacctgacaatagtacattgacatggatgaaa
tccaccactgtttgctctgcaagttctaaaatgaaattgaacatgcctggcagcactgct
gaacttgggaaatttcagtttcttggtaatactggattaaatggactggtggaaggatgc
ttagatctgttctcagcaaaggctgtgtatatggggcactctggcattgatatgcatgct
gtgtgtattcagcataaactttgcaatatgtctcttgaagagaatggtataacactattg
tatggacttcaaactactgaaaataagttgctgcactttgtggctccgaaatatactgcc
aaaatgctgtttgatggattgctggaattaatgaatgctgtaagaaagatgaagaaattt
cctgatcagagactgcagtggctgcgaaaacagtatgtcagcctttatcaggaggatgga
cgttatgaaggaccaactttggctcaagctgttgaactgtttggagggaggcgttggagt
acaagaaatacaagcccaggaaacctgataaaaagtgtagagaaaccaggtgtgcaaaga
aacaacactctgggaatcgtcacagctaagaaaaagaagaaagtgctcatgaggggtgaa
agtggagatggtactgatgatgaaatgacaactcgaaaagcaagaccttttaaggaaaat
cggagtagaagtggttcagaccctcaagatattgatgagcaagatgaaatagaaccaagt
cttctggttgctttttctggtaccagtaccttaccttccagaagaacacaatcgctgact
acctcagtaccacctagtgtaacacctggggtctcttcacctgtcagaccagtatcttca
cctgtgatgccatcatcagtaaaaggtcaatctagcgcatggagcagcagtagctggcat
ggaagagttaaaggaggattgaagggtttccaaacctgcatggtgtctgatagcaacatg
agttttgttgaatttatagagctcttcaagtctttcagtgttcgaagccgtaaggatttg
aaggatctttttgatgtatatactataccatgcaatcgattgagtgctgaatctgttccc
ctgtatacctctcttaagattgatgagaataccaatggactccagcctgatttagattta
ctgactaggaacatatcagatttgggcttgtttattaagagcaggcagcagctatcagac
aaccagcgacaaatatctgatgctattgctgcagcaagcattgttactaatggcactgga
gtagagagcacatctctggggatatttggagtgggcatccagcaactcaatgacttctta
gtaaattgtcaaggagaacattatacatatgatgaaatcctcagcattattcagaagttt
gagccaagcatcaacatgtgtcagcaaggactaatgtcatttgaaggatttgcacggttt
ttaatggataaagataattttgcttctgtgaacaatgagtcacaggaaaacacagaagat
ttactcttcccactgtcatattattacatcgaatcatcacataatacatatctcacagga
catcagcttaaaggagaatcctcagtagaactttacagccagattcttttacaaggctgt
agaagtgtggaattggactgctgggatggtgatgatggaatgcctgttatttatcatgga
catacactcacaactaagatttcttttaaggaagtagttgaagctattgaccgcaatgcc
tttgtcacctcagacatgccaatcatcatatcaattgaaaaccactgttccttgccccag
caacgaaaaatgtctgaaattttcaagaacacatttggagaaaagctggtaactaaattt
ttatttgagagtgacttttctgatgatcctatgctaccttctccccatcaactaagaaga
aaggttttgcttaaaaacaaaaagctcaaagctcatcagactccagtggatattttaaaa
cagaaggctcatcagctggcatacatgcaagctcaggcaagcaatggtggtaatttgggg
aatcttaccactactaatgaagaagaagaggatgaagaagatgagtatgactatgactat
gaatctctttctgatgataacattctggaagaccgacctgagaataagttaaccattgat
aagcttcagtttgaatacagtgaagaaactgctaagagaataaaaaagatggatagcact
gcgtacaacagtaaaggaaaggtttatgacatggaattaggtgaagaattttatctttct
caaaataaaaaagaaagtagacaaatagcaccagagttgtcagaccttgtcatctactgt
caagctgtaaaatttcctgggctgtcaactctaaatccatctggttctagcagagggaag
gaaagaaaaagcaggaagtccatatttggcaacaatcctggaaggctaagcccgggggag
cctgcgatgcttgccaaagcatctggaaaaggtgcctttgatagtgcacgacagacctgg
gaagaagcttgttcacctgcttttagccctacagcttctctcagctctataataaggaca
cctagatgctaccatatatcttctttgaatgaaaatgctgcgaagcgcttgtgcaggcga
tattctcagaagttgatacagcatacgacctgccagctgctgaggacatatccagctgct
acacgcattgactcctccaatcctcatccccttcttttttggctccatggggtacagcta
gtagcactaaactaccaaactgatgatcttcctctgcatttaaatgcagccatgtttgaa
gcaaatggtggctgtgggtatgttctgaaacctcctgtgctgtgggataagaactgccca
atgtaccaacacttctgtcctttagaaagagagctggacaatatggaaccagctatttat
tcgttgacgattgtgtctggacagaatgtttgtcctggtaacagcacaggaagcccctgc
attgaagtggatgtccttggcatgcctctagatagctgccattttcgtaccaagcccatt
catcgcaatactctcaaccccatgtggaatgaacagtttcttttccggattcacttcgag
gatctagtatttcttcgttttgcagttgttgaaaacaatagttcagctgtgatggctcaa
agaattattccactaaaggctttaaaaagagggtacagacatcttcagctacgaagcctt
cataatgaagtactagaaatctcaagtttgttcattaacagtagaagaatggaagaaaat
ccttctggaaacgctttgtctgctacttcgcagttcagcacagcagagaggagagcagct
gccatgtacaaagttacagtatgtggcattccagggccagaaccttttaccctttttact
gtaaagcaaggaaccactgtagctcagcttctgtatcaaattttcactaccacaaaaggc
attggaaagtatccagcagactattttttaatggaagagaaatgctttatatctaaagaa
agaaatgaatatagcaaaccaccattccaaagagtgcttggccctgaggaggagcttgtt
cagctcttgaacagctggttcccagaagaaggctatgttggaaggattatctttaaaaca
cgtgaggaaaacttgaacaggagaaatttctttcaggaggagaaagacgaagcagttact
gtttctgaagatgacagcttctttgttcaagtccacgatgtttccccagaacagcctcgg
acagtcatcaaagctcctcgcttcagtacagcccaggatgttatccagcagactttatgc
aaagccaaatattcctacagtattttgaacaatcccaatccaagtgattatgtccttttg
gaggaagtgacaaaagagcaagcaaacaagaagtcttcaacagccaaaacatctcagagg
attctttctgaccaagagtgtgtatttcaggctcagaataggtggaagggagctgggaaa
tttatcctcaaacttaaagagcaagtccaggctggtcgagatgataaaaagaaaggcatc
tcattagctaatgaacttaagaaattaacaaaatcaagtaagcagtaccggggctttata
actccacctttacaaacttcttcagatggcctccaaaataaagatgacaagactacttgc
agtttgactttcagtgacactgtggagtaa

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