Varanus komodoensis (Komodo dragon): 123020462
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Entry
123020462 CDS
T07701
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko04270
Vascular smooth muscle contraction
vko04350
TGF-beta signaling pathway
vko04510
Focal adhesion
vko04520
Adherens junction
vko04530
Tight junction
vko04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
123020462 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123020462 (ROCK1)
04520 Adherens junction
123020462 (ROCK1)
04530 Tight junction
123020462 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123020462 (ROCK1)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
123020462 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vko01001
]
123020462 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
vko03036
]
123020462 (ROCK1)
Enzymes [BR:
vko01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
123020462 (ROCK1)
Protein kinases [BR:
vko01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
123020462 (ROCK1)
Chromosome and associated proteins [BR:
vko03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
123020462 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
Cortex-I_coil
APH
Motif
Other DBs
NCBI-GeneID:
123020462
NCBI-ProteinID:
XP_044280175
Ensembl:
ENSVKKG00000007636
LinkDB
All DBs
Position
Unknown
AA seq
1376 aa
AA seq
DB search
MSTGESFESRFEKLGIMIKDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDTFLNKYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLSFP
DDNDISKDAKNLICGFLTDREARLGRNGVEEIKRHPFFKNDQWSWENLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNHQYLSSCTANSNDNRAST
NVDKSLLESLQKTIYQLEEQLHNEMQLKDEMEQKFRTSNIKLDKIMKELDEEGNQRRNLE
STVTQVEKENMLLQHKINEYQRKVEQENEKRRNVENEVSTLKDQLEDLKKISQHSHITNE
KIAQLQKQLEEANDLLRTESDTAARLRKSHTEMGKSVSQFESLNRELQERCRILESTKIQ
VEKDYYQLQAALEVERRDRSHESEIIGELQARLTSLQEEIKSLKNNLERVEEERKQAQDM
LNHSEKEKNNLEIDLNYKLKMLQQHLEQEINEHNINKARLTDKHQSIEEAKSAAMCEIEK
KVKEERAAREKAENRIVQIEKQCSMLDFDLKQSQQKLEHLNEQKERLEDEVKNLTLQLEH
EINRRLVIQNELKMHAIEADSLKGSEKQLKQEINTLLEAKRLAEFELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIDEKNKETQKKIQELQNEKETLAAQLDLAETK
AESEQLARALLEEQYFELTQESKKVASRNKQEIADKDNIISRLEETNNTLTKDVAFLTKE
NAELNEKIKKLEEDYKLKKQEEINSIKMQYEKNLNNERTLKTQAVNKLAEIMNRKDFKLD
RKKVNMQDYKKKEKENRKLQLELNQEKEKFNQMVIKYQKELNEMQAQIVDESTCKNELQM
QLDSKESDIEQLRSKILDLQQGMDSTSVASLQADETDGNIIESRMEGWLSIPNKGNIKRH
GWKKQYVVVSSRKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKDLEVEPVQPAEKTNFLNHKGHEFIPTLYHFPANCEACAKPLWHVFKPP
PAVECRRCHVKCHKDHLDKKEELIAPCKVSYDVTSARDMLLLASCQEDQKKWVSHLVKKI
PKTPPSTFVRASPRTLSSRSSANQSFRKVKNPSGKARSKDYGSVGDITHNENSSYC
NT seq
4131 nt
NT seq
+upstream
nt +downstream
nt
atgtcgacaggagaaagctttgaatctcggtttgaaaaattgggaataatgataaaggac
cccaaatctgaagtgaattcggactgtttattggatggattagatgcattggtgtatgat
ttggattttcctgctttaagaaaaaataaaaacatagacaccttcttaaataaatataaa
gacacaataaacaaaataagagatctccgtatgaaagctgaagattatgaagtggtgaaa
gtgattggcagaggagcatttggggaagttcaattggtaagacacaaatcatcacgaaag
gtctatgctatgaaacttttgagcaagtttgaaatgataaaaagatcagattctgcattc
ttttgggaagaaagagacatcatggcatttgcaaatagcccttgggttgtgcagttattt
tatgctttccaagatgaccgttatctttatatggtaatggaatacatgcctggtggagac
cttgtgaatttaatgagcaactatgatgttcctgagaaatgggcaagattttatacagca
gaagttgttcttgcattagatgcaattcactccatgggctttattcacagagatgtcaag
ccagataatatgctgctagataaatctggtcatttaaaactagcagattttggtacctgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacgccagactat
atatccccagaagtcttaaaatctcaagggggtgatggttactatggacgtgaatgtgac
tggtggtcagttggtgtctttttgtatgaaatgcttgttggagatacacctttttatgca
gattctttagttggaacatacagtaaaattatgaatcataaaaattctcttagcttccca
gatgataatgatatttctaaagatgcaaagaatcttatttgtggcttcttaactgacagg
gaagctagattaggccgaaatggtgtggaagaaatcaaacgacatccattcttcaaaaat
gaccagtggtcttgggaaaatcttagagatactgtagcacctgttgtgcctgatttaagt
agtgatattgacactagtaactttgatgatttggaggaagataaaggagaagaggaaaca
ttccctataccaaaagcatttgttggcaaccagctaccttttgtaggctttacatactac
agtaaccatcagtatttatccagctgtacagcaaattctaatgacaacagggcaagcacc
aatgtagataaaagtttgctggaatccttgcaaaaaactatctatcagcttgaagaacag
ctacataatgaaatgcaactgaaagatgaaatggaacaaaaattcagaacatccaacatt
aaactagacaagataatgaaggaattagatgaagagggcaatcaaagaagaaacttggaa
tcaacagttactcaggttgagaaggaaaatatgcttttacaacacaaaataaatgaatat
caaagaaaagttgaacaggagaatgagaaacgtcggaatgtagaaaatgaagtgtcaaca
ttaaaagatcagttggaagacttaaaaaaaattagccaacattcacatattacaaatgaa
aaaatagctcagttgcaaaagcaacttgaagaagccaatgatttactgaggacagagtca
gatactgcagcacgtttaagaaagagtcatacagaaatgggcaagtcagtaagtcagttt
gaatccttaaacagggaactgcaagagcgatgcagaatcctagagagtacaaaaatacaa
gtggaaaaggattattaccaactgcaagcagcactggaagtagaacgaagggataggagt
catgaatcagaaattattggagagctacaagctcgacttacatcattacaagaagaaatc
aaaagtttaaagaacaatcttgaaagagtagaagaagaaagaaaacaggcccaggacatg
cttaatcattctgaaaaggaaaagaataatttagaaattgatctaaactacaaactcaaa
atgttacaacagcatttagagcaagaaataaatgaacataacataaataaggctcgatta
actgacaagcatcaatcaattgaagaggccaagtcagctgcaatgtgtgaaattgaaaaa
aaggtaaaggaagaacgagctgcaagagaaaaggcagaaaatcgaatagttcagattgaa
aagcaatgttccatgttagactttgacctgaagcagtctcagcagaagctggagcacctt
aatgaacagaaagagagactagaagatgaggttaagaatctgactcttcagctggagcat
gagataaataggagattggtgatccaaaatgaactgaagatgcatgctatagaagcagat
agcttaaaagggtctgagaagcagctaaaacaggagatcaatacattgttggaagcaaag
agattagcagagttcgaattggctcagttggctaagcagtacagagggaatgaaggccag
atgcgtgaactgcaagatcaactagaagctgaacagtatttttctacactttacaaaact
caggttaaagaacttaaagaagaaattgatgaaaagaataaagaaactcagaaaaaaata
caagaattacaaaatgaaaaagaaactcttgctgcacaattagatcttgctgaaacaaaa
gctgaatctgagcagttggccagagcactccttgaagagcagtactttgaactaactcag
gagagcaagaaagtggcatcacgaaataaacaagaaattgctgataaggacaatatcata
agccggcttgaagaaacaaataatacattaactaaagatgtggcatttctgacaaaagaa
aatgctgaactaaatgaaaagatcaagaagctggaagaagactataaattgaagaaacaa
gaggaaattaacagtattaaaatgcagtacgaaaagaacctgaacaatgaaaggactctt
aaaacacaggctgtcaacaaattggctgagattatgaatcgaaaagattttaaactagat
agaaaaaaagtaaatatgcaagattacaagaaaaaagaaaaggaaaacagaaagttacaa
ttggaacttaaccaagaaaaggaaaaatttaatcagatggtaataaaatatcagaaggag
cttaatgaaatgcaagcgcaaattgtggatgagtctacatgtaaaaatgaacttcagatg
cagctagatagtaaggaaagtgatatagaacaattgcgcagtaaaattttggacctacaa
caaggcatggactctaccagtgttgccagtcttcaggcagatgaaactgatggaaatatt
atagaatcaagaatggagggatggctttcaataccaaacaaaggaaacataaaacgtcat
ggatggaagaagcagtatgttgtggtaagcagcagaaagattttgttctataacgatgaa
caggacaaagaacaatctaatccatccatggtattagatatagataaattattccatgtt
cgtccagtaactcaaggagatgtatatagagcagaaactgaagaaattcccaaaatattc
cagattctgtatgccaatgagggtgaatgccgaaaagatttggaagtagaaccagtgcag
ccagcagagaagacaaattttttgaatcataagggtcatgaatttatcccaacattatac
cactttccagccaactgtgaggcttgtgcaaagcctctctggcatgtatttaagccaccc
cctgctgtggaatgccggcgatgtcatgttaagtgccataaagatcatttggataaaaaa
gaagaattaattgcgccatgtaaagtgagttatgatgtaacttcagcaagagatatgttg
ttactggcatcatgtcaagaagatcaaaagaaatgggtttctcatttagtaaagaagatt
cctaaaacaccaccatccacttttgtccgtgcttctccaagaactctttcttcaagatcc
tcagcaaatcagtcattcagaaaagttaagaatccttcaggaaaagctaggtcaaaggac
tatggatctgtgggggacattacccataatgaaaattcaagttactgttaa
DBGET
integrated database retrieval system
