Varanus komodoensis (Komodo dragon): 123025767
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Entry
123025767 CDS
T07701
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko00280
Valine, leucine and isoleucine degradation
vko00640
Propanoate metabolism
vko00785
Lipoic acid metabolism
vko01100
Metabolic pathways
vko01210
2-Oxocarboxylic acid metabolism
Module
vko_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
123025767 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
123025767 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123025767 (BCKDHA)
Enzymes [BR:
vko01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
123025767 (BCKDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
PolC_DP2_central
Motif
Other DBs
NCBI-GeneID:
123025767
NCBI-ProteinID:
XP_044290684
Ensembl:
ENSVKKG00000012774
UniProt:
A0A8D2LA25
LinkDB
All DBs
Position
Unknown
AA seq
446 aa
AA seq
DB search
MAAAAASARAGLRSLRRLVLGRTPLPGRIAARGLRTAVFLQQQEEFTSLEEKPQFPGASA
EFIDKLEFIQPNVISGIPIYRVMDRQGQIVNPSEDPQLPKEQVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALDDTDLVFGQYREAGVLMHRGHPLDLFMAQCY
GNASDPGKGRQMPVHYGCKDLHFVTISSPLATQIPQAVGSAYAIKRENSNRIVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTYEQYRGDGIAARGPGYGIHSIRVD
GNDVFAVYNATKEARRRALAEHQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMVGRNWWDEEQEKSWRKKSRKRVMEAFEEAERKLKPKPQLLFSDVYSEMPRH
IQKQQESLERHLKQYGEHYPLDLYEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcgtcagctcgcgccgggctgcgctccctgcggaggctggtgctg
ggccgcaccccgttgcccggacggatcgcggcgcgggggctccgcacggcagtcttcctc
caacagcaggaagagttcacctcccttgaggaaaagcctcagttcccaggcgcctccgct
gagttcatagacaagcttgagttcatccagcccaatgtcatttcggggatccccatctac
cgggtcatggaccgacaggggcagattgtcaatcccagcgaggaccctcagcttccgaag
gagcaagtgctgaaattctacaagagcatgaccctcctcaacaccatggatcggatcctc
tatgagtcccagcggcagggtcgcatctccttttacatgactaactacggggaggagggc
acccacattggcagtgctgctgccctggatgacaccgacctggtatttggacaatatcgg
gaagcaggtgtcctcatgcacagggggcatccactggacctcttcatggcacaatgctac
ggcaatgccagtgacccagggaagggccgccaaatgcccgtccattacggctgcaaggat
ttgcactttgttaccatctcttccccgctagccacgcagatcccgcaagccgtcggctct
gcctatgccatcaagagggagaacagcaaccggatcgtgatctgctactttggggagggc
gcggccagcgagggcgatgcgcatgcaggtttcaacttcgcggccaccctcgagtgcccc
atcattttcttttgccgcaacaatggctacgccatctccacgccgacatatgagcagtac
cggggcgatggaattgctgcccgggggcctggctacggcatccactcgatccgggtggac
ggcaacgacgtctttgcggtgtacaatgccacaaaggaggcccggcgccgtgcccttgcc
gaacaccagccgttcctcattgaagcgatgacctacaggattgggcaccacagcacgagt
gacgacagctccgcctaccgctctgtggacgaagtgaattactgggacaaacaagaccac
cccatctctcgtctccgccactacatggtgggccgaaactggtgggatgaggagcaggaa
aagagttggcgcaagaaatcccgcaagcgggtcatggaggcctttgaagaagctgagcgc
aagttgaagcccaagcctcagctcctcttctctgacgtctactctgagatgcccaggcac
atccagaagcagcaggaatccctggagcgtcacctcaagcaatacggcgaacactacccc
ctggacctctacgagaaatga
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