Varanus komodoensis (Komodo dragon): 123026780
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Entry
123026780 CDS
T07701
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko00562
Inositol phosphate metabolism
vko01100
Metabolic pathways
vko04020
Calcium signaling pathway
vko04070
Phosphatidylinositol signaling system
vko04081
Hormone signaling
vko04082
Neuroactive ligand signaling
vko04261
Adrenergic signaling in cardiomyocytes
vko04270
Vascular smooth muscle contraction
vko04310
Wnt signaling pathway
vko04371
Apelin signaling pathway
vko04540
Gap junction
vko04621
NOD-like receptor signaling pathway
vko04912
GnRH signaling pathway
vko04916
Melanogenesis
Module
vko_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123026780 (PLCB2)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123026780 (PLCB2)
04371 Apelin signaling pathway
123026780 (PLCB2)
04020 Calcium signaling pathway
123026780 (PLCB2)
04070 Phosphatidylinositol signaling system
123026780 (PLCB2)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
123026780 (PLCB2)
04081 Hormone signaling
123026780 (PLCB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
123026780 (PLCB2)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
123026780 (PLCB2)
09152 Endocrine system
04912 GnRH signaling pathway
123026780 (PLCB2)
04916 Melanogenesis
123026780 (PLCB2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
123026780 (PLCB2)
04270 Vascular smooth muscle contraction
123026780 (PLCB2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vko04131
]
123026780 (PLCB2)
Enzymes [BR:
vko01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
123026780 (PLCB2)
Membrane trafficking [BR:
vko04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
123026780 (PLCB2)
Endocytosis
Macropinocytosis
Phospholipase C
123026780 (PLCB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLC-beta_C
PI-PLC-X
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
EF-hand_like
Fibrinogen_BP
ComZ
Motif
Other DBs
NCBI-GeneID:
123026780
NCBI-ProteinID:
XP_044292720
LinkDB
All DBs
Position
Unknown
AA seq
1213 aa
AA seq
DB search
MSVLTPILTPPEVKEYMTKGERFIKWDDDSTNAFPVILRVDPKGYYLYWTFQSKEMEFLE
ITSIRDTRIGKFAKIPKSQKLREVFNLDFPENNFFLKTLTVVSGPDMVDLTFHNFVSYKE
NVGKNWADDVMSIVRNPFILNASRYSFLEKILVKLKTQLNAEGKIPVKNIFQAFPADRKR
VEAALSACHLPKGKNDGINPEDFPESVYKTFLMKLCPRPEIDEIFTSHHSKAKPYMTKHH
LTTFINKKQRDSHLNDTLFPPAKPEQVQDLIEKYEPSMMNIQRGQLSPEGMVWFLCGPEN
SIVSQDKLLLHQDMSQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSPYPVILSFENHVDSPKQQAKM
ADYCRSIFGDMLLTEPLEKNPLKPGVPLPSPQDLMRKILIKNKKNQFIPGENPDILKKRK
SLEDEATEQAAPIESPDRSAELTEEVPEVEGDLGKLNEEEMKKLQSDEGTAGLEVTAYEE
MSSLVNYIQPIKFESFEISAQKNRSYVVSSFTEMKAYELLTKSPIQFVDYNKRQMSRIYP
KGTRMDSSNYMPQMFWNVGCQMVALNFQTADVPMQQNMALFEFNGQSGYLLKHDFMRRPD
KQFDPFSVNCIDVVVASTLSITIISGQFLSERSIRSYVEVELFGLPSDPKRRYRTKLTPN
ANSINPMWKEDAFVFEKILMPELASLRIAALEEGGKFIGHRIIPITAVCTGYHHVCLRSE
TNMPLTMPSLFVYVEMKDYVPDSWTGLTMALSNPIKFFNAHDEKAVKNQGTNSEKPNFQF
SLSAAQQNTNGILHATGTYSTPPSNGPEGPLAVGKEKTMKKPMEPETASIEELQQMKAFQ
KLLKKQEKELKELEQKGIKRREDQLQKYVILFTEVMAQAAKKKMPSTPKAFRKKSCRAPT
EESSAALLPVEVAESPDSRVLELKGKLEEELTELGEEQYDAIRKKKEQHATKQIAKIIEL
AREKHAAELKALKEISESDTKEMKKKLEGNRLDKIQTMAKNTTDKCIQERLKREINNAHI
REVVQMVKKLHEKQTKYQEILEKKQKACLEKIKENENQLQEAAFAEYEEKVRALSAEVQD
LVKDCARVCFPLEADRTKEEALKTASEGDQGLEQQLQKNNPMPEAVRQATQRAFWAENAE
EDDNSMHTQESKL
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtgcttacccctattctgaccccccctgaggtaaaggagtacatgacgaaaggt
gaacgcttcatcaagtgggatgatgattccacaaatgcttttcctgtcattctacgggtg
gatccaaagggatattacctatactggacatttcagagtaaggaaatggaatttttggag
ataacaagcattcgagacactagaatagggaaatttgccaagataccgaagagccagaag
ctccgagaggttttcaatttggatttcccagagaataacttctttctcaagacattgaca
gtggtttctggtcctgatatggtggatctcacctttcacaattttgtatcttataaagaa
aatgttggaaagaattgggcagatgatgtcatgagcattgttaggaacccctttatatta
aatgcttcccgttacagcttcctggaaaaaatactagtgaagctgaagacacagctgaat
gctgaggggaaaattccagtcaagaatatttttcaagcatttcctgcagacagaaaaaga
gtagaagctgcattaagtgcttgccaccttccaaagggaaaaaatgatggtatcaatcca
gaagacttccctgaatctgtgtacaaaacattcctgatgaaactatgccctcggccagag
attgacgagatatttacttcacatcattcaaaggccaagccatacatgaccaaacatcac
ctgacaacatttatcaacaagaaacagcgagattcccacctcaatgacacgcttttcccc
ccagctaagccagagcaagtccaggatctcatagagaaatatgagcccagtatgatgaat
attcagagaggacagctgtctccagagggaatggtctggtttctgtgtggcccagaaaac
agcatagtgtcccaggacaagctattgctgcaccaggatatgagccagccactgtcccac
tatttcatcaattcatcccacaacacctacctgacagctgggcagttttcaggaatctca
tctcctgaaatgtatcgccagacccttttggctggctgccgctgtgtggaactggattgc
tggaaggggcgccctccagacgaggagccgatcatcacgcatgggttcaccatgacaaca
gaaatattgttcaaggatgcaattgaggctattgcagaaagtgctttcaaaacctctccc
tacccagtgattttgtcttttgaaaatcatgtggactcgcccaagcagcaggctaaaatg
gctgactactgtagaagcatatttggggacatgctgctgacagaaccactggaaaaaaat
ccactaaaaccaggagttccactgccaagcccccaggatctaatgcgaaaaatattgatt
aagaacaaaaagaaccagttcatacctggggagaacccggatattctaaagaaaaggaag
agcttagaggatgaagcaactgagcaggccgcacctatagagagcccagacaggtcagca
gagttgactgaagaggtgcctgaagtagaaggagacttgggaaaactgaatgaagaagag
atgaaaaagctgcagtcggatgagggcactgcaggtctggaagtgaccgcttatgaagaa
atgtctagccttgttaattacatccaacccatcaaatttgaaagttttgaaatctcagca
cagaagaatcgaagttatgtggtttcttccttcaccgaaatgaaggcttatgagctcttg
accaaatcccccatccagtttgtggactataacaagaggcagatgagccgaatttatccc
aagggtactcggatggattcttctaactacatgcctcagatgttctggaatgttggctgc
caaatggtagctttaaacttccagacagcagatgtccctatgcagcagaacatggccctc
tttgaattcaatgggcagagtggctacctcctcaaacatgacttcatgcgtcgcccagat
aagcaatttgaccctttctctgtgaactgcattgatgtggtggtggcaagcacactctca
ataacaatcatttctggccagttcctctcagaacgtagtatcagatcatatgtagaagtg
gaattatttgggctgccaagtgatccaaaacgcagatacagaaccaagctgacaccaaat
gcaaattcaatcaaccctatgtggaaggaagatgcttttgtatttgaaaagattctgatg
ccagagctggcttctctcagaattgcggctttggaagaaggagggaagttcataggccat
cgcatcattcccatcactgctgtgtgcacagggtatcaccatgtttgccttcgtagtgag
accaacatgccacttacgatgccctcactgtttgtctatgtggagatgaaagactatgtt
cctgattcatggacaggtctcaccatggctctctccaacccaatcaagttttttaatgcc
catgatgaaaaggcagtgaaaaaccaagggactaattctgagaagcccaacttccaattt
agtctttcagctgctcagcaaaataccaatgggattctgcatgccacaggaacctacagt
actcctccttcaaatggacctgaaggacctttggctgtagggaaagaaaaaaccatgaaa
aaacccatggaaccagagactgctagcattgaagagctacagcagatgaaggcttttcaa
aagctgttgaaaaaacaggagaaggaactgaaggagctggagcagaagggcatcaagcgc
agagaagaccagttgcagaaatatgtcattcttttcacggaggtgatggcacaggctgcc
aagaagaaaatgccaagcacaccaaaagccttcagaaaaaagagttgcagggcccctaca
gaggagagcagtgcagcattacttcctgtggaggtggcagagagtcctgacagcagagtc
ttggagttgaaagggaagctggaggaggaactaactgagctaggagaggagcagtatgat
gccattcggaagaaaaaagaacagcacgccacaaagcaaattgctaagataatagaactt
gcaagagaaaagcatgcagccgaactgaaagcactaaaggagatctctgagagtgacaca
aaggaaatgaaaaagaaactagaggggaacagactggacaaaatccaaaccatggctaag
aatacaactgacaaatgtatccaggaaagattgaagagagaaatcaataatgcacacatc
cgtgaagtagtgcagatggtcaaaaagttgcatgaaaagcagactaagtatcaagaaata
ctggaaaaaaagcagaaagcctgcctagaaaagatcaaagaaaacgaaaaccagcttcag
gaggcggcatttgcagagtatgaagaaaaggtgagagctctcagtgcagaggtgcaagat
ttagtgaaggactgtgcaagagtgtgttttcctctggaggctgacaggacaaaagaagag
gccctaaagactgccagtgagggagaccaggggctggagcagcagctgcagaaaaacaac
ccaatgcctgaggcggtcaggcaagcgactcagagggcattctgggcagagaatgcggaa
gaggatgacaactccatgcatacacaagagagcaaattgtga
DBGET
integrated database retrieval system
