Varanus komodoensis (Komodo dragon): 123030410
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Entry
123030410 CDS
T07701
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko03030
DNA replication
vko03410
Base excision repair
vko03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
123030410 (POLE)
03410 Base excision repair
123030410 (POLE)
03420 Nucleotide excision repair
123030410 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
vko03032
]
123030410 (POLE)
03400 DNA repair and recombination proteins [BR:
vko03400
]
123030410 (POLE)
Enzymes [BR:
vko01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
123030410 (POLE)
DNA replication proteins [BR:
vko03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
123030410 (POLE)
DNA repair and recombination proteins [BR:
vko03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
123030410 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
DNA_pol_B_exo1
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
DUF5853
Motif
Other DBs
NCBI-GeneID:
123030410
NCBI-ProteinID:
XP_044300243
LinkDB
All DBs
Position
Unknown
AA seq
2419 aa
AA seq
DB search
MTGSRARSEGSREAWRVARETVKRLGRPRSFAGMAQRKGRGGGGYNSWRRRWATDTPAAD
GEGEAPRDDSSSTSALKRLERSQWTDKIDAQFGFERMKEPAERTGWLINMHPTEILDENK
RLVSAVDYYFIQEDGSRFKVALPYKPYFYIATQKGCDQEVSSFLAKKFQGKIAKLDTVPK
EDLDLPNHLVGLKRNYIKLSFNTVDDLLKVRKEITPAVKKNRERDQAVDTYTTMLASALA
GSSLSHKQEEASRKTADQMDNIVDMRECDVPYHIRLSIDLKIHVAHWYNVRHRGSSFPPE
ITRRDDLVERPDPVVLAFDIETTKLPLKFPDPETDQIMMISYMIDGQGYLITNREIVSED
IEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETMPAIMVTYNGDFFDWPFVEARA
AAHGMNMQQEIGFQKDNQGEYKASQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDP
VELDPEEMCRMATEEPQTLATYSVSDAVATYYMYMKYVHPFIFALCTIIPMEPDEVLRKG
SGTLCEALLMVQAYHANIIFPNKQEQEFNKLTEDGHVLDSETYVGGHVEALESGVFRSDI
PCRFKMNPAAFDFLLQRVEKTLRHAIEEEEGIPLDQVTNFQKVCDEIKVKLGSLRDVPNR
IECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRRMTWQWRGEFM
PASRSEYHRIQQQLESEKFPSLFPDGPPRAFHELTREEQAKYEKKRLADYCRKAYKKIHV
TKVEERVTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLAAAMEMGDASEVKRCKN
MEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGASIITQARELIEQIGRP
LELDTDGIWCVLPNSFPENFVIKSTNSKKPKVTISYPGAMLNIMVKEGFTNDQYQELVDP
ATLKYVSRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRR
GELQLVKIFQSSVFEAFLKGTTLEEVYASVAKVADYWLDVLYSKAANMPDSELFELISEN
RSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISKKPEGSPVTERAIPL
AIFQAELSVRRHYLRKWLKSPSLQDFNIRTILDWDYYIERLGSTIQKIITIPAALQQVKN
PVPRVQHPDWLHKKLLEKNDVYKQKKISELFTSEGKRQVCASLPREGLPGTQVADMEDFG
IARPAQPGVPVTTKRKRIPTTEESQQQSQNLELTQSWREILGPPPPTGTTKEERLVWLRY
HKKKWELQARQRQERRKRRRLADGKVVLGGGLIRAGPSKGLSSFLHRTARSILDLPWQIV
QIAETSQEGLFKLWAVIGSELHCLKLNVPRVFYINQRVPKPEESTVYRKVNRVLPRSSLV
YNLYEYSVPEDMYQEHINEISASLSAPDIEGVYETQVPLLLRALIRLGCLCMVNRTLVKH
LTGRESDTFDLEHLEMRSLAQFSYLEPGSIRHIYLYHHAQGNKALLGLFIPSQRKASVFI
LDTVRSNQMPNLTGMYASEHSAMMEKVGPELLPPGKHTFEVRAETDCKTVYRAIQRLLLG
YKDERRGPTLIAVQSNWDLKRLAGGMPVLEEFPLVPVQVSDDISYSVLDWQRHAARHMIR
RYLSLDTCLSQAFDMSRYYHIPIGNLPDDISTFGTDLFFSRHLHRHNHLLWISPTSRPDL
GGKEADDSRLVMELDERVSVEINHPGCYSTVCVELDLQSLAVNTILQSHHINDMEGASSM
CISFDVIQQASLEDMVTGNQAASAPASYDEAALCSNTFRVLKSVVVGWVKEITQYHNVYA
DNQVIHFYRWLRSPTSLLHDPALHRMLHNMMKKLFLQLVAEFKRLGSLVVYANFSRVILC
TKKRRIEDALAYVDYITSSIHSKEIFHSLTISFSRCWEFLLWMDPANYGGIRGKVPSRVH
YGQETNSKEAADVEESEGEEEEEEEENKEDGVGEGDIEELLENNWNVMQYLPQAASCQNY
FLMIVSAYIVAVYHSMKEEMQRNGPGSTPIKRRTNSQVSQEPVKETGAMPGMIAFSQEYV
SNELTQSVFTITQKIQKKVSGSRRTTEPSEMFPALPGSYLMLNNPALEFVKYVCKILSLD
NNITNQVSKLKRDLLRLIDVGEFSEEAQFRDPCRSHVLPEMICRNCNLCRDLDLCKGPVL
AQDGSVLPNWVCSNCQAQYDSDAIEMALVEALQKKLMAFTLQDLICQKCKGIKETHMPIY
CSCAGSFDLLLPTKTFLEHLKVFQSIAHHYHMPHLLENISWLLQMNPRLLWASLQFVFAL
GKTIERRPVCFMPHRSACRGVVPHCERLVRGQTQSDLSSRFGQGAGQQASPLPGPVFCWT
VGAQQNKSLGLWGSSLPRF
NT seq
7260 nt
NT seq
+upstream
nt +downstream
nt
atgacaggcagccgcgcgcgttcggagggatctcgcgaggcttggcgcgttgcgcgcgaa
actgtgaagaggctcgggcgaccgcggagctttgccgggatggcgcagaggaagggaagg
ggcggcggcggatataacagctggaggcgccgatgggcaaccgacacccctgcggcagat
ggcgagggagaggccccgcgggatgacagctcctcgacctctgctcttaagcgcttggag
cgcagccagtggacagacaagattgatgcacagtttggatttgagaggatgaaggaacct
gcagaaaggacagggtggttgatcaacatgcatccaacagagattttggatgagaataaa
cgcttggtcagtgcagtggattattatttcattcaggaggatggaagtaggtttaaggtg
gcgctgccatataagccctacttctacattgcaactcaaaagggttgtgatcaagaagtg
tcgtccttccttgccaagaagttccaaggcaaaatagcaaaactggacactgtacccaaa
gaggatctggacctgccaaatcatctggttggcctgaaaaggaactacatcaaactgtcc
ttcaacactgtggatgaccttttaaaagttcgcaaggagatcacacctgctgtaaagaag
aatagggaacgggatcaagctgtggacacttacaccaccatgctggctagtgctcttgcc
gggagcagcctgagccataagcaggaggaggcctccagaaagactgcagaccagatggac
aacatagtggacatgcgggagtgtgacgtgccctaccatatccgcctgtccatcgacctg
aagatccacgtggctcattggtacaatgttcgccaccggggtagcagcttcccaccagaa
atcacacgtcgagatgatttggtagaacggccagatcctgttgttctggcctttgacatc
gagacaacgaaactccctttgaaatttcctgatccagaaacagaccagatcatgatgatc
tcctacatgattgatggccagggttacttgatcacaaaccgggagattgtttcagaagat
attgaagattttgagtttacacccaaaccagaatatgagggccccttctgtgtctttaat
gaaccagatgaggcgcatcttattcagcggtggtttgagcatgttcaggaaaccatgcca
gctatcatggtgacttacaacggagacttctttgactggccctttgtggaagccagagcg
gcagctcacggaatgaatatgcagcaggagatcgggttccaaaaggacaaccagggtgaa
tacaaagcttcccagtgcatccacatggattgcctcaggtgggtcaagagagacagttac
ctcccagtggggagccacaacttgaaagcagcagctaaggcgaaactcggctatgaccct
gtggagctagaccctgaagagatgtgccggatggctactgaggagcctcagaccctggcc
acctactcagtgtctgatgctgttgccacctactacatgtacatgaagtatgtgcaccct
ttcatcttcgccctgtgtaccatcatcccaatggaaccagatgaggtgctccgaaagggc
tcggggactctgtgtgaggcgctgctcatggtccaggcctaccatgccaacatcatcttc
cccaacaagcaagagcaagagttcaacaaactgacggaggatgggcacgttctcgactca
gagacgtatgtggggggccacgtggaggcgctggagtccggggtcttccggagtgacatc
ccttgccgctttaagatgaaccctgctgcctttgacttccttctgcagcgtgtggagaag
acactgcgacacgccattgaggaagaggagggaattcccttggaccaagtgaccaatttc
cagaaggtgtgcgatgaaatcaaggtcaagctgggttccttgagggatgttcccaacagg
attgaatgccccttgatctaccatctggatgtgggggccatgtatcccaatatcatcctg
accaacaggctgcagccatcggcaatggtggatgaagccacgtgtgcggcctgcgacttt
aacaagccaggagccaactgccagcggaggatgacttggcagtggaggggagagttcatg
cccgccagtcgcagcgagtaccaccgcatccagcagcagctggagtcagagaagttcccc
tctctcttccctgacgggcctccacgggctttccacgaactgacccgagaggagcaagcg
aaatatgagaagaagcgcttggcagattactgccgcaaagcctacaagaaaatccacgtg
acgaaagtggaggagcgtgtcaccaccatctgccagcgggagaactccttctacgtggac
actgtgcgggcctttcgggaccgacgctacgagttcaaggggctgcataaggtgtggaag
aagaagctggctgcagccatggagatgggagacgcctcggaagtgaagcgctgcaagaac
atggagatcctgtacgattccttgcagttggcacacaagtgcatcctcaactccttttat
ggatacgtcatgcgcaaaggcgctcggtggtactccatggaaatggctggcatcgtctgc
ttcactggtgctagcatcatcacgcaggcccgagagctgatagagcagattgggaggccc
ttggagctggacacagatgggatctggtgtgtcctgccaaacagcttcccagaaaacttt
gtcatcaagtcaaccaacagcaagaagcccaaagtgacgatttcctacccaggtgccatg
ctgaacatcatggtgaaggaagggtttacaaatgatcagtaccaggagctcgtggacccg
gccactctcaaatatgtttcccgctcagagaacagcatcttttttgaagtggatgggcct
tacctcgccatgattctgccagcctccaaggaagagggaaagaagctgaagaaaaggtat
gccgtgtttaacgaagacggctccctcgccgagctgaaggggtttgaggtgaagcgccgt
ggggagctgcagctggtgaagatcttccagtcctccgtgtttgaggccttcctgaagggc
accaccttggaggaggtctatgcctcggtggccaaagtggcagactactggcttgatgtg
ctgtacagcaaggcggccaatatgcctgactcggagctgtttgagctgatctcggagaac
cgatccatgtcccggaaactggaggactatggagagcaaaaatccacttctatcagcaca
gccaaacgcctggctgagttcctgggggatcagatggtgaaggatgcaggcctgagctgc
cgatacattatctcaaagaaaccggaggggtctccagtcactgagagggccatcccactt
gccattttccaggctgagctctcggtgcgcaggcactatctccggaagtggctcaagagc
ccctccctgcaggacttcaacatccgaacgatcctggattgggactattacattgagagg
ctaggcagcaccatccaaaagatcatcaccatcccagcggcactgcagcaggtgaagaat
ccagttcctcgcgtccaacatcctgactggttgcataagaagctcttggagaagaatgat
gtgtacaagcagaagaaaatcagcgagctcttcacaagtgagggcaagagacaggtctgt
gcaagcctgcctcgggaaggcctcccaggcacccaagtcgccgacatggaggattttggt
atcgccaggcctgcccagccaggagtcccggtgacaaccaagcgtaaacggatccccacc
acggaggagagccagcagcagtcccagaacctggagctcacgcagtcctggcgggagatc
ctgggcccacccccccccactggcaccaccaaggaggagcgcctggtctggctgcgctac
cacaagaagaagtgggagctgcaggcacgtcagcgtcaggagcgccggaagaggaggcgg
ttggcagatggcaaggtggtcctgggtgggggactgatccgggctggcccctccaagggg
ctcagcagcttcctgcaccggacagcacgcagcatcctcgacctgccctggcagatcgtc
cagatcgcagagacaagccaggaaggcctcttcaagctgtgggctgtgatcgggagcgag
ctgcactgcctgaagctcaacgtgcctcgggtcttctacatcaaccagcgtgtccccaag
ccggaggagagcactgtctataggaaggtgaacagagtccttcctcgctccagcttggtt
tacaacctgtacgagtactcggtgcccgaggacatgtatcaggagcacatcaatgagatc
agcgccagcctctctgctccagacatcgagggggtgtatgagacccaggtgccattactg
ctgcgggccttaattcgcctgggctgtctgtgcatggtcaacaggactttggtgaaacac
ctcactggccgagagtcagataccttcgatctggaacaccttgagatgcgttccttggcc
cagttcagctacctggagccagggagcatccggcacatctacctgtaccatcacgcccaa
ggcaacaaggcactgctgggtctgttcatcccttctcaacgcaaagcgtctgtcttcata
ttggacacggtgcggagcaaccagatgccaaacctcaccggcatgtatgcttcagagcac
agcgccatgatggagaaggtgggcccagaactgcttccgccagggaaacacacctttgaa
gtccgagcagagacggactgcaagacggtctacagggccatccagcgcctcctgctgggc
tacaaggatgagcgcaggggccccaccctcattgccgtgcagtcgaactgggacctgaag
cggctggcgggtggcatgccagtcctggaggagttcccgttggtcccagtccaggtctcc
gatgacatcagctacagcgtcctggactggcagcgccacgctgcccggcacatgatccgc
cgctacctcagcttggacacgtgcctgtctcaggcctttgacatgagcaggtattaccac
atccccatcgggaacctccccgatgacatctccaccttcggcacagacctgttcttctcc
cgtcacctccaccgccacaatcaccttctgtggatctctcccacgtcccgccccgacctg
gggggcaaagaggcggacgacagtcgcctagtgatggagcttgacgagagagtctctgtc
gagatcaatcacccaggctgctattccacagtctgtgtggaactggacctccagagcctt
gctgtgaacaccatcttgcagtcccaccacatcaacgacatggaaggggcctccagcatg
tgcatcagcttcgacgtgatccagcaggcatcgctggaggacatggtcactgggaaccag
gcagccagcgccccggccagctacgacgaagcggccctttgctccaacactttcagggtc
ctgaagagtgtggtggtgggctgggtgaaggagatcacgcagtaccacaacgtctatgct
gacaaccaggtgatccatttctaccgctggctgcgctccccaacatcgcttctccacgac
cctgccctgcaccgcatgctgcacaacatgatgaagaagctcttccttcaactggtggcg
gagttcaagcgcctcggctcactggtggtttacgccaacttcagccgcgtcatcctgtgc
accaagaagcgccgcatcgaggatgccctcgcctacgtggactacatcaccagcagcatc
cattcaaaagaaatcttccactctttgaccatttccttctcgcgctgctgggagttcttg
ctttggatggacccagccaattacggtgggatcagagggaaggttccttcccgggtccac
tacgggcaggagaccaatagtaaagaggcagcagatgtagaagagagtgaaggagaggag
gaggaggaggaggaagagaacaaggaagatggagtgggcgaaggtgacatagaggagctg
ctggaaaacaactggaatgtcatgcagtatctgccccaggcagcctcctgtcaaaattat
ttcctcatgattgtgtctgcctacattgtagccgtgtaccatagcatgaaagaggaaatg
cagcggaatggccctggaagcacccccatcaagaggcgaacgaacagccaggtttcccag
gagcctgtgaaagagacgggggccatgcctggcatgattgccttctcccaggagtacgtc
tccaatgagcttacccaaagcgtcttcaccatcacccagaagatccagaagaaggtgagt
ggctctcgacgtaccacggagccctctgagatgttccctgccctgcccggctcctacctg
atgctcaacaacccggcactggagtttgtgaaatacgtctgtaagatactgtccctggac
aacaacatcaccaaccaggtgagcaagctgaagagggacctgcttcgcctaatcgatgta
ggtgaattctcagaggaggcccagttccgggatccctgccgctcccacgtcctcccagag
atgatctgcaggaactgcaacctgtgcagagacttggacctctgcaagggccctgtcctc
gctcaggatggatccgtgctgccgaactgggtgtgctccaactgccaagcccagtatgac
tcggatgccatagagatggccctggtggaagccctgcagaaaaagctgatggccttcacc
cttcaggacctgatttgccagaagtgcaaaggcatcaaggagacccacatgcccatctac
tgcagctgcgccggcagctttgacctcctgttgcccaccaagaccttcctggagcacctg
aaagtcttccagagcattgcccatcactatcacatgccccacctgctggagaacatctcg
tggctgctgcagatgaaccctcggcttctctgggccagcctgcagtttgtcttcgccctg
ggaaaaaccatcgagaggcgcccggtttgcttcatgccacacagaagcgcatgcagaggt
gtggtgcctcactgtgagcgactcgtacgaggtcagactcagagtgacttgtcttccaga
ttcggccagggagctggtcaacaagcaagcccgcttcctggccccgtcttttgctggact
gtgggagctcagcagaacaaaagccttggattatggggcagctcattgcccagattttaa
DBGET
integrated database retrieval system
