Varanus komodoensis (Komodo dragon): 123035715
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Entry
123035715 CDS
T07701
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
vko
Varanus komodoensis (Komodo dragon)
Pathway
vko00562
Inositol phosphate metabolism
vko01100
Metabolic pathways
vko04020
Calcium signaling pathway
vko04070
Phosphatidylinositol signaling system
vko04081
Hormone signaling
vko04082
Neuroactive ligand signaling
vko04261
Adrenergic signaling in cardiomyocytes
vko04270
Vascular smooth muscle contraction
vko04310
Wnt signaling pathway
vko04371
Apelin signaling pathway
vko04540
Gap junction
vko04621
NOD-like receptor signaling pathway
vko04912
GnRH signaling pathway
vko04916
Melanogenesis
Module
vko_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
vko00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123035715 (PLCB1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123035715 (PLCB1)
04371 Apelin signaling pathway
123035715 (PLCB1)
04020 Calcium signaling pathway
123035715 (PLCB1)
04070 Phosphatidylinositol signaling system
123035715 (PLCB1)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
123035715 (PLCB1)
04081 Hormone signaling
123035715 (PLCB1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
123035715 (PLCB1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
123035715 (PLCB1)
09152 Endocrine system
04912 GnRH signaling pathway
123035715 (PLCB1)
04916 Melanogenesis
123035715 (PLCB1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
123035715 (PLCB1)
04270 Vascular smooth muscle contraction
123035715 (PLCB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vko04131
]
123035715 (PLCB1)
Enzymes [BR:
vko01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
123035715 (PLCB1)
Membrane trafficking [BR:
vko04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
123035715 (PLCB1)
Endocytosis
Macropinocytosis
Phospholipase C
123035715 (PLCB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PLC-beta_C
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
123035715
NCBI-ProteinID:
XP_044310095
Ensembl:
ENSVKKG00000010139
LinkDB
All DBs
Position
Unknown
AA seq
1219 aa
AA seq
DB search
MAGAQPGVHALQLQRVRVSANLKKGATFVKWDDDSTNVTSIFLRIDPHGFFIYWTDQNKV
QESELLDISLVKDARCGKHARAPKDPKLREHLDGGNAGGRLENRMLTIVYGPDLVNISYL
NLVAAQEDIAKEWSEEIFSLATNLLAQNMSRDAFLEKAYTKLKLQVTTEGRIPLKNIYRL
FSSDRKRVETALEACSLPSARNDSIPQEDFTPEVYRDFLSNLCPRPEIDLIFLEFGAKSR
PYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNNNLAKKGQISVDGFMR
YLSGEENGVVSPEKLDLNEDMSQPLSHYLINSSHNTYLTAGQLAGNSSVEMYRQVLLSGC
RCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDS
PKQQAKMAEYCRLIFGDALLMEPLEKYPLERGVPLPSPADLMYKILVKNKKKSHKSADGS
AKKKLSEQASNACSDASSGFEPSSPGAGEVEIESDDDDDYDDDCKKSSMDEGTAGSEAMA
TEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKALEQLTKSPVEFVEYNKMQLSR
IYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMR
RPDKHFDPFTESIVDGIVANTLSVKIISGQLLSDKKVGTYVEVDMFGLPVDTRRKALKTK
TSQGNAVNPVWEDETIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVSAIRPGYHYICL
RNERNQPLMLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEE
EIKKEANQGDVPSEAHNEPKPAPAENGVNHTTSLTPKPSTQVVSSQPAPGSVKVPAKTED
LIQSVLTEVEAQTIEELKQQKAFVKLQKKHYKEMKDLVKKHHKKTTDLIKEHTTKYNEIQ
NDYLRRRAVLEKTAKRDSKKKGESSSPDHSSSTVEQELATLDSEMTQKLIELKEKQQQQL
LNLRQEQYYSEKYQKQAHIKLLIQKLTDVAEECQTNQLKKLKEICEREKKELKKKMDKKR
QEKITEAKSKDRSQVDEEKTEMIRSYIQEVVQYIKRLEDAQSKRQERLVEKHKEIRQQIL
DEKPKLQAELDQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSTTSSLASEGGKLNHK
PQQNEDPEDTPAKVFDTPL
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atggctggggcacagccaggggtccacgctcttcagctccagcgcgtccgcgtctctgcc
aacctcaagaagggcgccaccttcgtcaagtgggacgatgactccactaatgtgacatca
atttttctccggatagacccacacggatttttcatatactggacagatcaaaataaggta
caggaatcagagctcttagatattagccttgtcaaagatgcccggtgtggaaaacatgct
cgcgctccgaaggatccaaagctccgtgaacatctggatggagggaatgcaggaggacga
ctagaaaaccgaatgcttactatcgtgtatggccctgatctggttaatatatcatacttg
aacttagtagcagctcaggaagatattgcaaaggaatggtcagaggaaatcttcagcctg
gcaacaaacctcctggcacagaacatgtcaagggatgcttttctggaaaaagcatacaca
aaacttaaattgcaagtcactacggagggacgcattcctttgaaaaatatttatcgcttg
ttctcctcagacagaaaacgtgttgagactgcactggaagcttgtagccttccttcagcc
aggaatgattcgattcctcaagaggacttcactccagaagtgtatagagactttctgagc
aacctgtgccctcgtcctgaaattgacctcatcttcctggagtttggtgctaagagcaga
ccatatcttactgttgaccagatgatggaatttataaacttgaagcaacgagacccacgg
ttaaatgaaattctctatccacctttgaagcaggaacaggttcagcagctgattgagaaa
tatgaacccaacaataatttggccaagaaagggcagatatcagtggatggatttatgaga
tatttgagtggagaggaaaatggagtggtttcacctgaaaaactggatttgaatgaagat
atgagccagcctctgtctcactatcttatcaattcctcgcacaacacctacctcacagct
gggcagctggctggtaactcttccgtagagatgtaccgccaagtgctgttgtctggctgc
cgctgtgttgagctggattgctggaaaggtcgaacagctgaagaagagccagtcattacc
catggattcaccatgacaactgaaatatcctttaaggaagtgatagaagctattgctgaa
tgtgcatttaagacatcccctttccctatcctcctctcttttgaaaatcatgtagattcc
cctaaacagcaggcaaaaatggcagaatattgtagattaatatttggtgatgctttgctg
atggagccactggaaaaatacccgcttgaacgtggtgttcctcttccaagcccagcagac
ctgatgtacaaaattctggtgaagaataaaaagaagtcccacaagtcggcagacggcagt
gcaaagaagaagctgtctgaacaagcatccaatgcatgcagcgatgcatccagtgggttt
gagccttcctctcctggagcaggggaagtggaaattgagagtgatgatgacgatgattat
gacgatgactgcaaaaaatcatcaatggatgaaggaactgctggaagtgaggccatggcg
actgaagaaatgtccaacttggttaattacatccagcctgtgaagtttgagtcatttgaa
acatctaaaaaacggaacaagagttttgaaatgtcttcctttgtggaaaccaaagcactc
gagcagctcacaaaatctcctgttgagtttgtggagtataacaaaatgcagctgagccgg
atttatccaaaagggacacgtgttgattcctcaaattacatgcctcagctcttctggaat
gcaggctgtcagatggttgctcttaacttccaaactgtagatttatctatgcaaataaac
atggggatgtatgagtataatggtaaaagtgggtacagattaaagccagaattcatgaga
aggccagacaaacacttcgatcctttcactgaaagtattgtagatggaatagtggcaaac
actttgtctgtgaagattatttctggacagttactttctgacaaaaaggttggcacttac
gtagaagtggatatgtttggtctgcctgtggacacaaggcggaaagctctcaagaccaag
acatctcaaggcaatgctgtgaatccggtatgggaagatgaaaccatagtttttaagaag
gtcgtcctgccttcactagcatgtctgaggatagccgtctatgaagaaggaggaaaattc
attggtcatcggatattaccagtttcagcaattcgaccaggttatcattatatttgcttg
aggaatgaaaggaatcagcctttgatgttgccagccttatttgtatacatagaggttaaa
gactatgtgcctgatacttatgcagatgtcattgaagcattatccaatccaatcagatat
gtgaacttgatggagcagagagcaaagcagctggcagcattgactctggaggatgaagaa
gaaataaaaaaggaggcaaatcagggagatgtcccttcagaagctcacaatgaaccaaag
cctgcaccagctgaaaatggagtaaaccacaccacttccctcacccccaaaccatctact
caggttgtttccagccaaccagcaccaggttctgtgaaagtgccagcaaaaacagaagat
ctcattcagagtgtcttgacagaagttgaagcacaaaccattgaggagttgaagcaacaa
aaagcgtttgtgaaacttcagaagaagcactacaaagaaatgaaggatctcgtgaagaaa
caccacaaaaaaaccaccgatctaataaaggagcatactacaaagtacaacgaaattcaa
aatgactatctgcggcggagggcagtcttggagaaaacagctaaaagagacagtaagaaa
aaaggtgaaagcagtagtccagaccacagctcttcaactgttgaacaagagttggctacc
cttgattccgaaatgacccaaaagctaatagagcttaaggaaaagcaacagcagcagctg
cttaatcttcggcaagagcaatattacagtgaaaagtaccagaagcaagcacatattaaa
ttgcttattcaaaagctgacagacgtagcagaggaatgccagaccaatcagttgaagaaa
ctgaaagaaatttgtgaaagagaaaagaaagaactgaagaaaaagatggacaaaaagagg
caggagaaaatcactgaggctaaatcaaaggatcgaagtcaagtggatgaggagaagaca
gaaatgattcggtcttacattcaggaggtggtgcaatacattaaaaggcttgaagatgct
cagagtaaaaggcaggaaagacttgtggagaaacacaaggagattcgtcagcaaatactg
gatgaaaaacccaagttgcaggctgaacttgatcaagaatatcaagacaaattcaaaaga
ctcccattggaaattctggaatttgttcaagaagccatgaaaggcaaaattagtgaagat
ggagaccacagctctaccacttcttccctggcatctgaaggaggaaaactgaaccataaa
ccacagcaaaatgaagatccagaagatactccagcaaaagtgtttgatacaccactctag
DBGET
integrated database retrieval system