KEGG   Varanus komodoensis (Komodo dragon): 123035715
Entry
123035715         CDS       T07701                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
vko  Varanus komodoensis (Komodo dragon)
Pathway
vko00562  Inositol phosphate metabolism
vko01100  Metabolic pathways
vko04020  Calcium signaling pathway
vko04070  Phosphatidylinositol signaling system
vko04081  Hormone signaling
vko04082  Neuroactive ligand signaling
vko04261  Adrenergic signaling in cardiomyocytes
vko04270  Vascular smooth muscle contraction
vko04310  Wnt signaling pathway
vko04371  Apelin signaling pathway
vko04540  Gap junction
vko04621  NOD-like receptor signaling pathway
vko04912  GnRH signaling pathway
vko04916  Melanogenesis
Module
vko_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:vko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    123035715 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    123035715 (PLCB1)
   04371 Apelin signaling pathway
    123035715 (PLCB1)
   04020 Calcium signaling pathway
    123035715 (PLCB1)
   04070 Phosphatidylinositol signaling system
    123035715 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123035715 (PLCB1)
   04081 Hormone signaling
    123035715 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    123035715 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    123035715 (PLCB1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123035715 (PLCB1)
   04916 Melanogenesis
    123035715 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123035715 (PLCB1)
   04270 Vascular smooth muscle contraction
    123035715 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vko04131]
    123035715 (PLCB1)
Enzymes [BR:vko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     123035715 (PLCB1)
Membrane trafficking [BR:vko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    123035715 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    123035715 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 123035715
NCBI-ProteinID: XP_044310095
Ensembl: ENSVKKG00000010139
LinkDB
Position
Unknown
AA seq 1219 aa
MAGAQPGVHALQLQRVRVSANLKKGATFVKWDDDSTNVTSIFLRIDPHGFFIYWTDQNKV
QESELLDISLVKDARCGKHARAPKDPKLREHLDGGNAGGRLENRMLTIVYGPDLVNISYL
NLVAAQEDIAKEWSEEIFSLATNLLAQNMSRDAFLEKAYTKLKLQVTTEGRIPLKNIYRL
FSSDRKRVETALEACSLPSARNDSIPQEDFTPEVYRDFLSNLCPRPEIDLIFLEFGAKSR
PYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLIEKYEPNNNLAKKGQISVDGFMR
YLSGEENGVVSPEKLDLNEDMSQPLSHYLINSSHNTYLTAGQLAGNSSVEMYRQVLLSGC
RCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDS
PKQQAKMAEYCRLIFGDALLMEPLEKYPLERGVPLPSPADLMYKILVKNKKKSHKSADGS
AKKKLSEQASNACSDASSGFEPSSPGAGEVEIESDDDDDYDDDCKKSSMDEGTAGSEAMA
TEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKALEQLTKSPVEFVEYNKMQLSR
IYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKSGYRLKPEFMR
RPDKHFDPFTESIVDGIVANTLSVKIISGQLLSDKKVGTYVEVDMFGLPVDTRRKALKTK
TSQGNAVNPVWEDETIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVSAIRPGYHYICL
RNERNQPLMLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEE
EIKKEANQGDVPSEAHNEPKPAPAENGVNHTTSLTPKPSTQVVSSQPAPGSVKVPAKTED
LIQSVLTEVEAQTIEELKQQKAFVKLQKKHYKEMKDLVKKHHKKTTDLIKEHTTKYNEIQ
NDYLRRRAVLEKTAKRDSKKKGESSSPDHSSSTVEQELATLDSEMTQKLIELKEKQQQQL
LNLRQEQYYSEKYQKQAHIKLLIQKLTDVAEECQTNQLKKLKEICEREKKELKKKMDKKR
QEKITEAKSKDRSQVDEEKTEMIRSYIQEVVQYIKRLEDAQSKRQERLVEKHKEIRQQIL
DEKPKLQAELDQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSTTSSLASEGGKLNHK
PQQNEDPEDTPAKVFDTPL
NT seq 3660 nt   +upstreamnt  +downstreamnt
atggctggggcacagccaggggtccacgctcttcagctccagcgcgtccgcgtctctgcc
aacctcaagaagggcgccaccttcgtcaagtgggacgatgactccactaatgtgacatca
atttttctccggatagacccacacggatttttcatatactggacagatcaaaataaggta
caggaatcagagctcttagatattagccttgtcaaagatgcccggtgtggaaaacatgct
cgcgctccgaaggatccaaagctccgtgaacatctggatggagggaatgcaggaggacga
ctagaaaaccgaatgcttactatcgtgtatggccctgatctggttaatatatcatacttg
aacttagtagcagctcaggaagatattgcaaaggaatggtcagaggaaatcttcagcctg
gcaacaaacctcctggcacagaacatgtcaagggatgcttttctggaaaaagcatacaca
aaacttaaattgcaagtcactacggagggacgcattcctttgaaaaatatttatcgcttg
ttctcctcagacagaaaacgtgttgagactgcactggaagcttgtagccttccttcagcc
aggaatgattcgattcctcaagaggacttcactccagaagtgtatagagactttctgagc
aacctgtgccctcgtcctgaaattgacctcatcttcctggagtttggtgctaagagcaga
ccatatcttactgttgaccagatgatggaatttataaacttgaagcaacgagacccacgg
ttaaatgaaattctctatccacctttgaagcaggaacaggttcagcagctgattgagaaa
tatgaacccaacaataatttggccaagaaagggcagatatcagtggatggatttatgaga
tatttgagtggagaggaaaatggagtggtttcacctgaaaaactggatttgaatgaagat
atgagccagcctctgtctcactatcttatcaattcctcgcacaacacctacctcacagct
gggcagctggctggtaactcttccgtagagatgtaccgccaagtgctgttgtctggctgc
cgctgtgttgagctggattgctggaaaggtcgaacagctgaagaagagccagtcattacc
catggattcaccatgacaactgaaatatcctttaaggaagtgatagaagctattgctgaa
tgtgcatttaagacatcccctttccctatcctcctctcttttgaaaatcatgtagattcc
cctaaacagcaggcaaaaatggcagaatattgtagattaatatttggtgatgctttgctg
atggagccactggaaaaatacccgcttgaacgtggtgttcctcttccaagcccagcagac
ctgatgtacaaaattctggtgaagaataaaaagaagtcccacaagtcggcagacggcagt
gcaaagaagaagctgtctgaacaagcatccaatgcatgcagcgatgcatccagtgggttt
gagccttcctctcctggagcaggggaagtggaaattgagagtgatgatgacgatgattat
gacgatgactgcaaaaaatcatcaatggatgaaggaactgctggaagtgaggccatggcg
actgaagaaatgtccaacttggttaattacatccagcctgtgaagtttgagtcatttgaa
acatctaaaaaacggaacaagagttttgaaatgtcttcctttgtggaaaccaaagcactc
gagcagctcacaaaatctcctgttgagtttgtggagtataacaaaatgcagctgagccgg
atttatccaaaagggacacgtgttgattcctcaaattacatgcctcagctcttctggaat
gcaggctgtcagatggttgctcttaacttccaaactgtagatttatctatgcaaataaac
atggggatgtatgagtataatggtaaaagtgggtacagattaaagccagaattcatgaga
aggccagacaaacacttcgatcctttcactgaaagtattgtagatggaatagtggcaaac
actttgtctgtgaagattatttctggacagttactttctgacaaaaaggttggcacttac
gtagaagtggatatgtttggtctgcctgtggacacaaggcggaaagctctcaagaccaag
acatctcaaggcaatgctgtgaatccggtatgggaagatgaaaccatagtttttaagaag
gtcgtcctgccttcactagcatgtctgaggatagccgtctatgaagaaggaggaaaattc
attggtcatcggatattaccagtttcagcaattcgaccaggttatcattatatttgcttg
aggaatgaaaggaatcagcctttgatgttgccagccttatttgtatacatagaggttaaa
gactatgtgcctgatacttatgcagatgtcattgaagcattatccaatccaatcagatat
gtgaacttgatggagcagagagcaaagcagctggcagcattgactctggaggatgaagaa
gaaataaaaaaggaggcaaatcagggagatgtcccttcagaagctcacaatgaaccaaag
cctgcaccagctgaaaatggagtaaaccacaccacttccctcacccccaaaccatctact
caggttgtttccagccaaccagcaccaggttctgtgaaagtgccagcaaaaacagaagat
ctcattcagagtgtcttgacagaagttgaagcacaaaccattgaggagttgaagcaacaa
aaagcgtttgtgaaacttcagaagaagcactacaaagaaatgaaggatctcgtgaagaaa
caccacaaaaaaaccaccgatctaataaaggagcatactacaaagtacaacgaaattcaa
aatgactatctgcggcggagggcagtcttggagaaaacagctaaaagagacagtaagaaa
aaaggtgaaagcagtagtccagaccacagctcttcaactgttgaacaagagttggctacc
cttgattccgaaatgacccaaaagctaatagagcttaaggaaaagcaacagcagcagctg
cttaatcttcggcaagagcaatattacagtgaaaagtaccagaagcaagcacatattaaa
ttgcttattcaaaagctgacagacgtagcagaggaatgccagaccaatcagttgaagaaa
ctgaaagaaatttgtgaaagagaaaagaaagaactgaagaaaaagatggacaaaaagagg
caggagaaaatcactgaggctaaatcaaaggatcgaagtcaagtggatgaggagaagaca
gaaatgattcggtcttacattcaggaggtggtgcaatacattaaaaggcttgaagatgct
cagagtaaaaggcaggaaagacttgtggagaaacacaaggagattcgtcagcaaatactg
gatgaaaaacccaagttgcaggctgaacttgatcaagaatatcaagacaaattcaaaaga
ctcccattggaaattctggaatttgttcaagaagccatgaaaggcaaaattagtgaagat
ggagaccacagctctaccacttcttccctggcatctgaaggaggaaaactgaaccataaa
ccacagcaaaatgaagatccagaagatactccagcaaaagtgtttgatacaccactctag

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