KEGG   Vulpes lagopus (Arctic fox): 121472045
Entry
121472045         CDS       T07435                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg00562  Inositol phosphate metabolism
vlg01100  Metabolic pathways
vlg04015  Rap1 signaling pathway
vlg04020  Calcium signaling pathway
vlg04022  cGMP-PKG signaling pathway
vlg04062  Chemokine signaling pathway
vlg04070  Phosphatidylinositol signaling system
vlg04071  Sphingolipid signaling pathway
vlg04072  Phospholipase D signaling pathway
vlg04081  Hormone signaling
vlg04082  Neuroactive ligand signaling
vlg04261  Adrenergic signaling in cardiomyocytes
vlg04270  Vascular smooth muscle contraction
vlg04310  Wnt signaling pathway
vlg04371  Apelin signaling pathway
vlg04540  Gap junction
vlg04611  Platelet activation
vlg04613  Neutrophil extracellular trap formation
vlg04621  NOD-like receptor signaling pathway
vlg04713  Circadian entrainment
vlg04720  Long-term potentiation
vlg04723  Retrograde endocannabinoid signaling
vlg04724  Glutamatergic synapse
vlg04725  Cholinergic synapse
vlg04726  Serotonergic synapse
vlg04728  Dopaminergic synapse
vlg04730  Long-term depression
vlg04742  Taste transduction
vlg04750  Inflammatory mediator regulation of TRP channels
vlg04911  Insulin secretion
vlg04912  GnRH signaling pathway
vlg04915  Estrogen signaling pathway
vlg04916  Melanogenesis
vlg04918  Thyroid hormone synthesis
vlg04919  Thyroid hormone signaling pathway
vlg04921  Oxytocin signaling pathway
vlg04922  Glucagon signaling pathway
vlg04924  Renin secretion
vlg04925  Aldosterone synthesis and secretion
vlg04926  Relaxin signaling pathway
vlg04927  Cortisol synthesis and secretion
vlg04928  Parathyroid hormone synthesis, secretion and action
vlg04929  GnRH secretion
vlg04933  AGE-RAGE signaling pathway in diabetic complications
vlg04934  Cushing syndrome
vlg04935  Growth hormone synthesis, secretion and action
vlg04961  Endocrine and other factor-regulated calcium reabsorption
vlg04970  Salivary secretion
vlg04971  Gastric acid secretion
vlg04972  Pancreatic secretion
vlg04973  Carbohydrate digestion and absorption
vlg05010  Alzheimer disease
vlg05016  Huntington disease
vlg05017  Spinocerebellar ataxia
vlg05022  Pathways of neurodegeneration - multiple diseases
vlg05142  Chagas disease
vlg05143  African trypanosomiasis
vlg05146  Amoebiasis
vlg05163  Human cytomegalovirus infection
vlg05200  Pathways in cancer
vlg05415  Diabetic cardiomyopathy
vlg05417  Lipid and atherosclerosis
Module
vlg_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121472045 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    121472045 (PLCB3)
   04310 Wnt signaling pathway
    121472045 (PLCB3)
   04371 Apelin signaling pathway
    121472045 (PLCB3)
   04020 Calcium signaling pathway
    121472045 (PLCB3)
   04070 Phosphatidylinositol signaling system
    121472045 (PLCB3)
   04072 Phospholipase D signaling pathway
    121472045 (PLCB3)
   04071 Sphingolipid signaling pathway
    121472045 (PLCB3)
   04022 cGMP-PKG signaling pathway
    121472045 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    121472045 (PLCB3)
   04081 Hormone signaling
    121472045 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    121472045 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121472045 (PLCB3)
   04613 Neutrophil extracellular trap formation
    121472045 (PLCB3)
   04621 NOD-like receptor signaling pathway
    121472045 (PLCB3)
   04062 Chemokine signaling pathway
    121472045 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    121472045 (PLCB3)
   04922 Glucagon signaling pathway
    121472045 (PLCB3)
   04929 GnRH secretion
    121472045 (PLCB3)
   04912 GnRH signaling pathway
    121472045 (PLCB3)
   04915 Estrogen signaling pathway
    121472045 (PLCB3)
   04921 Oxytocin signaling pathway
    121472045 (PLCB3)
   04926 Relaxin signaling pathway
    121472045 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    121472045 (PLCB3)
   04918 Thyroid hormone synthesis
    121472045 (PLCB3)
   04919 Thyroid hormone signaling pathway
    121472045 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    121472045 (PLCB3)
   04916 Melanogenesis
    121472045 (PLCB3)
   04924 Renin secretion
    121472045 (PLCB3)
   04925 Aldosterone synthesis and secretion
    121472045 (PLCB3)
   04927 Cortisol synthesis and secretion
    121472045 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121472045 (PLCB3)
   04270 Vascular smooth muscle contraction
    121472045 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    121472045 (PLCB3)
   04971 Gastric acid secretion
    121472045 (PLCB3)
   04972 Pancreatic secretion
    121472045 (PLCB3)
   04973 Carbohydrate digestion and absorption
    121472045 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    121472045 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    121472045 (PLCB3)
   04725 Cholinergic synapse
    121472045 (PLCB3)
   04728 Dopaminergic synapse
    121472045 (PLCB3)
   04726 Serotonergic synapse
    121472045 (PLCB3)
   04720 Long-term potentiation
    121472045 (PLCB3)
   04730 Long-term depression
    121472045 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    121472045 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    121472045 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    121472045 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    121472045 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121472045 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    121472045 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    121472045 (PLCB3)
   05142 Chagas disease
    121472045 (PLCB3)
   05143 African trypanosomiasis
    121472045 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121472045 (PLCB3)
   05016 Huntington disease
    121472045 (PLCB3)
   05017 Spinocerebellar ataxia
    121472045 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    121472045 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121472045 (PLCB3)
   05415 Diabetic cardiomyopathy
    121472045 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    121472045 (PLCB3)
   04934 Cushing syndrome
    121472045 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vlg04131]
    121472045 (PLCB3)
Enzymes [BR:vlg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121472045 (PLCB3)
Membrane trafficking [BR:vlg04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121472045 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121472045 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 121472045
NCBI-ProteinID: XP_041578951
LinkDB
Position
11:complement(76459586..76474737)
AA seq 1230 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYSRLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWAEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPSTGVPNS
SVRKRPLEQSNSALSESSAATDPSSPQLGSPSSESCPGLSNGEEVGLEKPSLEPQKSLGE
DGLPRGPNTLGSADREDEEEEEEEEEQADPKKPTSDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCYEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASPETCQETPSQQP
GSQLTPNPTPSPLDTPPRRPPGPATAPTSPSLSSPGQRDDLIASLLSEVAPIPLEELRGH
KALVKLQNRQERELRELHKKHQRKAVALTRRLLEGLAQARVESRCRHRPGVLGGENEKEE
GEEVKRYQEFQKRQVQSLLELREAQVDTEAERRLEHLRQAQQRLREVVLDAHTTQFKKLK
EMNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQK
QRQERLVAGQQQVLQQLAEEEPKLLAQLAQECQEHRARLPQEIRQSLLGETPEGLGDRHL
VACASNGHAPGSSGHLSGADSESQEENTKL
NT seq 3693 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggagacctccagtcggaacctg
gtaaccctgcgtgtagattccaacggcttctttctatactggactggacccaacatggag
gtggacacactggacattagttccatcagggacacgcgaacaggtcgttactcccgcctg
ccaaaggaccccaagatccgggaggtgctgggctttgggggccctgatacccggctagag
gagaagttgatgacggtggtggccgggccagacccggtgaatacaacattcttgaacttc
atggctgtgcaggatgacacagccaaggtctgggccgaggagctgttcaagctggctatg
aacatcctggctcagaacgcctccaggaataccttcctgcggaaagcatacaccaagctg
aagctgcaggtgaaccaggatggacggatcccggttaagaatatcctgaagatgttttca
gcagataaaaagcgagtggagaccgcactagaatcctgtggcctcaatttcaaccggagt
gaatccatccggcccgatgagttttccttggaaatctttgagcgattcctgaataagttg
tgtctgcggccggacattgacaagatcctgctagagataggtgctaagggcaagccatac
ctgacgctggagcagctcatggacttcatcaaccagaagcaacgggacccgaggctcaac
gaagtgctgtacccacccctgcggccctcccaggctcggctgctcattgaaaagtatgag
cccaaccagcagttcctggagcgagatcagatgtccatggagggcttcagccgctacctg
ggaggtgaagagaatgggatcctgcccctggaggccctggatctgagcgctgacatgacc
cagccactcagtgcctatttcattaactcctcacacaacacctatctcacagcggggcag
ctggctgggacctcgtcggtggagatgtaccggcaggcgctgctgtggggctgccgctgt
gtggagctggatgtgtggaaagggcggccgcctgaggaggagcccttcatcacccacggc
ttcaccatgaccactgaggtgccgctgagagatgtgctcgaggccattgcagaaaccgcc
ttcaagacctctccctatccagtcatcctctccttcgagaatcacgtagactcagcgaag
cagcaggccaagatggccgagtactgccgttccatctttggggacgcgctgctcatcgac
ccactggacaagtacccgctggccccaggtgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcgacaccagcccagcactggtgtccccaacagc
tctgtgcgcaagcggccgctggagcagagcaactcggccctgagtgagagctctgccgcc
actgacccctcctcacctcagcttgggtcccccagctctgagagctgcccaggcctgagc
aatggggaagaggtgggcctggagaagcctagcctggagcctcagaagtctctgggcgag
gatgggctcccacggggccccaacactcttggatctgctgaccgtgaggatgaggaagaa
gaggaggaagaggaggaacaggcagatcctaaaaagccaacctcagatgagggcactgcc
agcagtgaggtcaatgccactgaggaaatgtcaacactggtcaactacattgagcctgtc
aagttcaagtcctttgaggctgctcgaaaaaggaacaaatgctatgagatgtcatccttc
gtcgaaaccaaggccatggagcaactgaccaagagccccatggagtttgtggaatacaat
aaacagcagctcagccgcatctaccctaagggtacccgcgtggactcgtccaactacatg
ccccagctcttttggaacgtgggctgccagcttgttgcgctcaacttccagaccctggat
gtggcaatgcagctcaacgcaggtgtgttcgagtacaatgggcgcagtggctatctgctc
aaacctgagtttatgcggcggccagacaagtccttcgatcctttcaccgaagtcattgtg
gatggcattgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctatccgac
aggaaggtgggcatctatgtggaggtggacatgtttggcctccccgttgacacgcggcgc
aagtaccgtactcggacctctcaagggaactcattcaaccctgtgtgggatgaggaacct
tttgacttccccaaggtggtgctacccacactggcttcgctgcgcatcgcggcctttgag
gaaggcggcaagtttgtggggcatcggattctgcccgtctctgccatccgctcagggtac
cactacatctgtctgcggaatgaggccaaccaaccactttgcctgccagccctgctcatc
tacactgaagcctctgactatattcctgatgaccaccaagactacgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagttggccgccctcatt
ggggagagtgaggctcaggccagcccagagacatgccaggagactccgtctcagcagccg
gggtcccagctaaccccaaaccctacacctagcccgctggacacacccccgcgccggccc
ccaggccctgccacggcccctaccagcccctccctcagcagcccagggcagcgggatgac
ctcatcgccagcctcctctcagaggtggccccaatcccgctggaggagctccgaggccat
aaggccctggtgaagctccagaaccggcaagaacgagagctgcgggagctacataagaag
caccagcggaaggccgtcgccctcacccgccggctgcttgagggcctggctcaggcccgg
gtggagagcaggtgccggcatcggccaggtgtcctaggcggggagaacgaaaaggaagag
ggagaggaggtaaagcggtatcaggagttccagaagagacaggtgcagagtctgttggag
ctacgggaggctcaggtggacacagaggccgagcggaggctggagcacctgagacaggct
cagcagcggctcagggaagttgtcctggatgctcacacaactcagttcaagaagctgaag
gagatgaatgagagggagaagaaggaattgcagaagattctagacaggaagcgtcacaac
agtatctcagaggccaagactagggagaaacataagaaggaggcggaactgacagagatt
aaccgtcggcacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaag
cagcggcaggaacgcctggtggctgggcagcagcaggtcctacagcagctggctgaagag
gagcccaagctgctggcccagctggcccaggagtgtcaggagcatcgggcaaggctgccc
caggagatccgccagagcctgctgggcgagacaccggaggggctgggggacaggcatctg
gtggcctgtgccagcaacggtcacgcacctgggagcagcgggcacctgtctggcgctgac
tcagagagccaagaggagaatacgaagctctga

DBGET integrated database retrieval system