Vulpes lagopus (Arctic fox): 121472591 Help Entry 121472591         CDS       T07435                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:vlg00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     121472591 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:vlg03032]     121472591 (TOP2A)    03036 Chromosome and associated proteins [BR:vlg03036]     121472591 (TOP2A) Enzymes [BR:vlg01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      121472591 (TOP2A) DNA replication proteins [BR:vlg03032]  Eukaryotic type   DNA Topoisomerases    121472591 (TOP2A) Chromosome and associated proteins [BR:vlg03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     121472591 (TOP2A)   Centrosome formation proteins    Centriole proteins     121472591 (TOP2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  121472591 NCBI-ProteinID:  XP_041579762 LinkDB All DBs Position 12:complement(39239882..39269638) Genome browser AA seq 1531 aa AA seqDB search MEVSPLQPVNENMQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ IWVYDEDIGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMDNMGRAGEMELRPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVDVVKKKNKGGVAVKAHQVKSHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKN STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDQTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE ELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPTDLWKEDLATFVEELEAVETKEKQEEQIGFPGKGGKG KGKKTQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKNENTEGSPQEESIEIEGLKQ RLEKKQKREPGTKTKQTTLPFKPIKKGKKRNPWSDSESDMSSNESNFDVPPREVEPRRAA TKNKFTVDLDLDNSFSDFEERIQDEDSVPSDVSPHKTKASPKRTAKELKPQKSAPSVMDL DADDAKDSVPLSPGSTADFSAETEIVNPLPKKKVAVKKIAPKSQSSTSTTGAKKGAAPKG TKKDPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTATNKKSKGESEDFHL DLDSAVAPRAKSGRARKPIKYLEESDEDDLF NT seq 4596 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccactgcagccggtaaatgaaaacatgcaaatcagcaaaacaaagaaa aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg gaacatattttgctccgcccggacacctacattggctctgtggaattagtgacccagcaa atatgggtttacgatgaagatattggcatgaactatagagaagttacctttgtccctggg ttgtacaaaatctttgatgagattctggtcaatgctgcagacaacaaacaaagggaccca aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagcactc atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggggccaaattgtgtaacatattcagtacaaagtttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatgggaagg gctggtgagatggaactcaggccatttaatggggaagattacacatgtattaccttccag cctgacttgtccaagtttaaaatgcaaagcctagataaagacattgttgcactgatggtt agaagagcatacgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat aaactaccggtaaaaggattccgtagctacgtagatatgtatctgaaggataaggtagat gaaactggcaatccattgaaaattatccatgaacaagtaaaccccaggtgggaagtatgt ttaacaatgagtgaaaaaggctttcagcaaattagcttcgtcaacagcattgctacctcc aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgatgtt gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaagtcacatg tggatttttgtgaatgccttgattgaaaacccaacctttgactctcagacaaaagaaaac atgactttacaagtcaagagctttggatcgacatgccaattaagtgaaaaattcatcaaa gctgcaactggctgtggtattgtggaaagcattctaaactgggtaaagtttaaggcccaa atccaattaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa cttgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact gagggagactcggctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa tatggagttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaattaataatatcatcaagatcgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcataac tggccctctcttctacggcatcgttttctggaggaatttatcactccgattgtaaaggtg tctaaaaacaaacaagaaatggcattctatagccttcctgaatttgaagaatggaagaat tctactccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggtaccagcaca tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtattcagttcaaatac tctggtcctgaagatgatgctgccatcagcttggcctttagcaagaaacagacagatgat cgaaaggaatggttaactcatttcatggaagatagaagacaacggaagttacttggcctt cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgactttataaat aaggaacttatcctgttctcaaattctgataacgagagatctatcccatctatggtggat ggcttgaaaccaggtcaaagaaaggttttgtttacttgtttcaaacggaatgacaagcga gaggtgaaggttgcccagttggctgggtcagtggctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattataaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcagcccattggtcagtttggtactaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttattgtttccacca aaagatgatcagactttaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg tacattcccattatacccatggtgctgataaatggtgctgaaggaattggtactgggtgg tcctgcaaaatccccaactttgatattcgtgaagttgtaaataatatcaggcgtttgatg gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa gagctggctccaaatcagtatgtgattagtggtgaagtggctatacttaattccacaacc attgaaatttcagagcttcctgtcagaacatggacccagacctataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccacctctcataacagattatagggagtac catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaactggcagaggca gagagagtggggctacacaaagtcttcaaactccaaactagtctcacatgcaactccatg gtgctttttgaccatgtaggttgtttaaagaaatatgacacagtgttggatattctaaga gacttctttgaactaaggcttaaatattatggattaagaaaagaatggcttctaggaatg cttggcgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataattattgaaaataagcctaagaaagaattaattaaagttctgattcagagg ggatatgattcggatcctgtgaaggcttggaaagaagctcagcaaaaggtaccagatgaa gaagagaatgaagagagtgacaatgaaaatgaagctgaaaagagtgactctgtaagagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggagaag aaggatgaactgtgcaagctgagaaatgaaaaagagcaagaactagaaacattaaagaga aagagtccaacagatttgtggaaagaagacttggctacttttgttgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggatttccagggaaaggagggaaagga aaggggaaaaaaacacaaatggctgaagttttgccttctccttgcgggaaaagagtcatc ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag aatgaaaacactgaagggagccctcaagaagagagtatcgaaatagaaggtctgaaacaa aggttggagaagaaacagaaaagagaaccaggtaccaagacgaagcaaactacattgccg tttaaacccatcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagatatg agcagtaatgaaagtaactttgatgtccctccacgagaggtagagccacggagagcagca acaaaaaacaaattcacagtggatttggatttagacaacagtttctcagattttgaagaa agaattcaagatgaggattctgttccatcagatgtcagcccacataagaccaaagcttcc ccaaaacgtactgccaaagaactgaagccacagaaaagtgccccttcagtaatggacctt gatgctgatgatgccaaggacagtgtaccactttctccaggttctactgctgatttctcg gctgaaactgaaattgtaaacccccttcctaaaaagaaggtggccgtgaagaagatagcg ccaaaaagtcagtcttccacctccactacaggtgcaaaaaaaggggctgcaccaaaagga accaaaaaggatccaggcttaaattctgatgtctctcaaaagcctgatcccccaaaaacc aaaaatcgccgcaaaaggaagccatccacttctgatgattccgactctaattttgagaag atgatttctaaaacagccacaaacaagaaatccaagggggagagtgaagacttccatctg gacctagactcagctgtggctcctcgggccaaatctggacgtgcaaggaaacctataaag tacctcgaagaatcagatgaagatgatctgttctaa

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