Vulpes lagopus (Arctic fox): 121479445
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Entry
121479445 CDS
T07435
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00230
Purine metabolism
vlg00670
One carbon pool by folate
vlg01100
Metabolic pathways
vlg01523
Antifolate resistance
Module
vlg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121479445 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121479445 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121479445 (GART)
Enzymes [BR:
vlg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
121479445 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
121479445 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
121479445 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
121479445
NCBI-ProteinID:
XP_041590988
LinkDB
All DBs
Position
20:11084207..11117076
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIAGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNTILQRTVDGMQQEGMPYTGVLYAGIMLTKEGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRAAITVVMASKGYPGDYTKGVEITGFTEA
HALGLEVFHAGTALKDGKVVTNGGRVLTVTAIQENLLLALEEAKKGLSAIKFEGAFYRKD
IGYRAIAFFQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFRDPLLACGTDGVGTKLKIAQQCDKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLDTTEAVVTGIARACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQSWRVPRIFSWLQQEG
HLSEEEMARTFNCGVGAALVVSKDLTEQILKDIKQHKEEAWVIGKVVACPEGSPRVKVRH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAIRLGENGKIRWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaatcggcagtggaggaagggagcataccctggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcactgcc
tgcttagaaaagatttcaaataccgctatctccatcagtgaccacactgcccttgctcag
ttctgcaaagatgagaaaattgaattcgtggttgttggaccagaggcacctctggctgct
ggaatcgctgggaacctgacatctgcaggagtgcgatgcttcggtcccactgcagaagca
gctcaattagagtctagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacggtggaaagctttcaccaaacctgaagaggcctgcagctttataatgagtgca
gacttccctgctttggttgtaaaggccagtggtcttgcagctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcagggctgtacaggagattatgcaggataaagctttt
ggagcagctggagaaacaattgtcatcgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggactgtggcccccatgcccccagcacaagaccataagcga
ttgctggaaggagatcatggccccaacacagggggaatgggcgcctattgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaacaccattcttcagagaacagtggat
ggcatgcagcaggagggcatgccatacacaggtgttctctacgctggtataatgctgacc
aaggagggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttggatggcctg
ctctgcacatctctgcctgtttggcttgataaccgtgctgccataactgtggtaatggca
agtaaaggctatccaggagattacaccaagggtgtggagataacagggtttactgaggct
cacgctttaggactggaggtgttccatgcaggcactgccctgaaagatggcaaagtggtg
actaacggaggtagagtccttacggtaacagcaatccaggaaaatctcctcttggccctt
gaagaagcaaagaaaggactatctgctataaaatttgagggagccttttacaggaaggac
attggctatcgtgccatagccttcttccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtccaaaaaattaaacctttagcaaaagct
acttccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcagagatcctcttctggcatgtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtgataaacatgatactattggtcaagatttggttgcaatgtgt
gtcaatgacattctagcccaaggggctgagccccttttcttcctcgattacttttcctgt
ggaaaacttgacctcgatacaactgaagcagttgtcactggaattgccagagcttgcaga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctccg
ggagaatatgacctagctggttttgccgttggtgccatggagcgggatcagaaacttcct
cacctggaaagaatcactgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtcaggaaaattgtagcaaaatcttccctccagtactcgtct
ccagcacccgatggctgtggtgaccagaccttaggggacttacttctaactccaacccga
atctacagccattcgctgttacctgtcctacgttcaggacatgtgaaggcctttgcccat
attactggtggaggattgctagaaaacatccccagagtccttcctcagaaatttggggtg
gatttagatgcccaaagctggagggtccccaggatcttttcatggctacagcaggaagga
cacctctctgaagaagagatggcgagaacatttaactgtggagttggggctgccctcgtg
gtatcaaaggatctgacggagcagattctgaaggatattaagcagcacaaggaagaagcc
tgggtgattggcaaagtggtggcatgtcctgaaggttctcctcgtgtgaaagtcaggcat
ctgatagaaactatgcaaataaatgggtcagtattagagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctgcaagctcttatagacagtactagggagcccagtagctgtgcacacattgttgttgtt
atctccaacaaagctgcagtggctggtttagataaagcggaaagagctggaattcccacc
agagtaatcaaccataaattatataaaagtcgtgtagaatttgacactgccattgaccaa
gtccttgaagagtattccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatgggatgggaagatgctcaacatccacccctccttgctccct
tcttttaagggttcaaatgcccatgagcaagccctggaagctggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtcggaaagagtgaaattagcagag
cataaaatatttcctgcagccctccagctggtagccagtggagctataaggcttggagaa
aatggcaagatccgttgggtcacagaggattga
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