Vulpes lagopus (Arctic fox): 121484672 Help Entry 121484672         CDS       T07435                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:vlg00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     121484672 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:vlg03036]     121484672 (SYNE1) Chromosome and associated proteins [BR:vlg03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     121484672 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Bromo_TP Motif Other DBs NCBI-GeneID:  121484672 NCBI-ProteinID:  XP_041600107 LinkDB All DBs Position 2:complement(99522560..99973139) Genome browser AA seq 8833 aa AA seqDB search MAASRTTSRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPLVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSGSTSSVDSMVSAETASPPSKRKVA TKIQGNAKKALLKWVHYTVAKQTGIEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGR SNRENLEEAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNTGTDGQ ENDEILPGFPSFANSIQNFKREDRLILKETKVWIEQFERDLTRAQMTESNLQDKYQSFKH FRVQYEIKRKQIEHLIQPVHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVELLLQNYISFIENTKFFEQYEVTYQILKQTAEMYIQADGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQTEHAKKDFFRNLPHW IQQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEY TDCVTALSDFAMGAHKKLSEPLEVSFLNVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLI TKESSQEEANEMFATMSGLKEQLTKVKDCYSPLLYESQQLLIPLEELEKQMTFFYDSVGK INEILTVLEHEAQSSAVFKQKQQELSACQESCKKTMTQIEKGSQNVQKFMTLSSVLKHFD QTKLHRQIADAHGAFQNMMKKIGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK GNPEDLLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQG EAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLVPQEGSEKIIKEHRIFFSDKGPHHV CEKRLQLIEELCLKLPGRDPVRNTPETCHVTLKELRAAIDTTYMKLVEDPDKWKDYTSRI SQFSSWISAKETELKGFKNEPIDTANHGKVKHAVEEIRNDVTTKGETLNWLKSRLKVLIE VSSENEAQKQGDELAKLSGSFKALVALLSEVEKMLSNFGDCVQYKEIVKSSLEELISGSK EVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIQQAQQGEGGLPGQVREE LRKLESTLDNMEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSYSSLE SLSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKSIKEQVKKLEDT LEEDIKTMEMVKNKWDHFGNNFETLSIWITEKEKELNTLETSSSAMDMQINQIKVIIQEI QSKLSSITELEESAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQ QQKFEENLRKIQKSVSEFEDKLADPVKICSSATETYKVLQEHMDLCQALEALSSTVATTS ANAQKVANRGSCVQEAAALQQRYQEMQSQAKERQTALEKLLAHWQRLEKELSTFLTWLER CEAITSSPEMDISSDRVKVESELQSIQALQNEVVSQASVYSNLLQLKESLFSVASKDDVK MMKLHLEQLDERWRDLPQIISKRIAFLQSVVAEHQQFDELLLSLSVWIKLFLSELQSTSE ISITDHQAAFTRHKDHAAEVESKKGELQSLQDHLVKLGALVRAESLPLLQGKAEDCFQLF EEASQVVERRQLALAQLAEFLQSHVSLSGVLHRLRHTVEATNSMNRKQTDLLEKDLNHAI QDAKSLESVAISLDSVLAKAQYHLKSGSSEQRTSCRTTADHLCSELERIQNLLGIKQSEA DALAVLKKAFQDQKEELLKSIEDIEERTDKERLKELTRQALQQRLRVFNQLEDELNSHEH ELCWLKDKAKQIAQKDVAFASEVDREVNRLEVTWDDTKKLIHENQGQCCGLIDLMREYQN LKSAVSKVLENASNVIATRTTIKDQEDLKWALSKHETAKNEMCNKQKELDNFTSKGKQLL FELKKIHSSDFILVKTDMESTVDRWLDISEKIEENMDRLRVSLTIWADVLSSKDEIDGWC NSSVPRLAESISNLNNSLRAEEFLKEFESEVKNKALRLEELHCKVNDLKELTKNPETPPD LQFVEADLRQKLEHAKEITEEAKGTLKDFTAQSTQVEKSINDITSWLTKVEESLMNCAQT ETWEGLKKVKEIQKELQSQQSNISSTQENLNSLCRKYHSVELESLGSALTGLIKNQEAVS QLCSKTQASLQDSLEKHFNESMQEFQEWFSGIKAAAKESSDRTGDSKVLEAKLHHLQNIL DSISDGQSKLDAVTQEGQTLYAHVSKQIVGSIQEKIIKANEEFQAFLKQCLKDKQTLQDC ALELGSFEDQHRKLNLWIHEMDERLSTENLGESKQHIPEKKNEVHKVEMFLGELLAARES LDKLSQRGQLLSEEGHGAGKEGRLCSQLLTNYQNLLRMTKEKLRSCQVALQEHEALEEAL QSMWSWVKTIQDRLAAAESTIGSKDTLEKRLLQIQDILLMKGEGEVKLNMAIGKGEQALR SSNKQGQKVIQTQLQTLKDVWADIMSSSIHAQSTLESVISKWNDYLEWKNQLEQWMELVD QKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHAGALQHLTSKSRELYQKTENESFKETA QEELKTQFNDIITVSKEKMRKAEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDMSGDS SATQKKLSKIKELMDSREIGASRLSRVELLAPTVKQNTSASGCELVDTEMQALRADWKQW EDSVVQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTTWAQQLALLEGKNTDK EIVECWQKGQEILDALQKAEPKTEDLKSQLNELCRFSRDLSTYSGKVSSLIKEYNCLCLQ ASKGCQNREQILQQRFRRAFKDFQQWLVNAKITTAKCFDIPQNINEVSTNLQKIQEFLSE SENGQHKLNMMLSKGELLSTLLTKEKADGIQAKVVTAKEDWKNFHSNLHQKESALENLKI QMKDFEVSAEPVQDWLSKTEKLVQESSNRLYDLPAKRREQQKLQSVLEEINCYEPQLNRL REKAQQLWEGQAASKSFMHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQ DWLTDAVHMLDSYCHPTSDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSP EGIPAIQQQLQSVKDMWASLSSAAIRCKSQLEGALSKWTSYQDDVRQFSGWMDSMEASLN ESERQYAELREKTSALGKAKLLSEEVLSYSSLLETIELKGAGMTEHYVTQLEFQDLQERY RAIKERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDRHSVLEGDAHTHETTLR DLQELQVRCAEGQALLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLTETRTQF NNVVNKLRLMEQKYQQVDEWLKTLENKVKVRTGRQSNRAAKEIQLHQMKKWQEEVTAYKD EVEEVGARAQEMLDENHVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESELS LNSYSDWYTSTHKNFKNVATKIDRVDKVMMGKKMKMLEGLLKDMEKGHSLLKSTREKGER ALKYLEDSEAETLRNEIHEHVEQLKELTSTVRKEHMTLEKGLLLAKEFSDKYKALTQWIS EYQEILHTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVKSVREKGEALLELVQDVTLK DEIDKLQSDYKDLCDAGKEHVCSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLMET SSLETITQQLAHHKAMMEEIAGFEDRLNNLKIKGDNLISQCADHLQAKLKQNVHAHLQGT SDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLTAIHPDLKPSQLPPLSRAEAV KQVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWG EIKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQCKQASMTAIT ERVNKLTKKQESPEHKEISHLNDQWLDLCLQSNNLCLQREEDLQRTRDYHDCMNVVEVFL EKFTTEWDNLARSDAESTAVHLEALKKLALALQDRKQAIEDLKDQKQKMIEHLNLDDKEL VKEQTSHLEQRWFQLEDLVKRKIQVSVTNLEELNVVRSRFQELMEWAEEQQPNISEALKQ SPPPDVAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQIIQKALSDAQSH VNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQV KTCKSAQASLKTYQNEVTGLWAQGRELMKGATEQEKSEVLGKLQELQSVYDTVLQKCSHR LQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESAELHTQLAKYQHILEQSP EYENLLLTLQRTGQAILPSLNEVDHSYLNEKLNALPLQFNVVVALAKDKFYKVQEAILAR KEYASLIELTAQSLSELEDQFLKMNKVPTDLIVEEALSLQDGCRALLREVSGLGEAVDEL NQKKESFRSTGQPWQPDKMLHLVTLYHRLKRQAEQRVNLLEDTTSAYQEHEKMCHQLEKQ LEAVKTEQSKVNEETLPAEEKLKMYHSLAGSLQDSEIILKRVTVHLEDLVPHLDPLAYEK AKQQIQSWQEELKLLTSAIGATVTECESRMVQSIDFQTELSRSLDWLRSVKAELSGPVCL ELSLQDIQEEIRKIQIHQEEVQSSLRIMNALSNKEKEKFTKAKELISADLQHTLAELSEL DGDIQEALRTKQAALTQIYSQCQRYYQVFQAANDWLEDAHEMLQLAGNGIDVESAEENLK SHMEFFSTEDQFHRNLEELQGLVASLDPLIKPTGKEDLAQKMASLEDKSQRIIQDSHAQL DLLQRCAAQWQDYQKAREEVIELMNDAEKKLSEFSLSKTSSSHEAEEKLSEHKSLVSVVN SFHEKVVALEDKTLQLEKTGNDASKAAISRSMTTVWQRWTRLRAVAQDQEKILEDAVDEW KSFNNKVKKATEIIDQLQDKLPGSSAEKASKAELLTLLDFHDTLILELEQQQLALGLLRQ QALSMLQDGATKSPREEPSIVQEITAMQDRCLNIQEKVKSNGKVVKQELKEREVVETQIN SVKSWVQETKEYLGNPTIEIDAQLEELQILLTEATNRRQNIEKMTEEQKNKYLGLYSILP SEVSLQLAEVALDLGTIHDQIQDKVREVEQSKAMSQEFSRQIQKIAKDLTTILSKLRAKT DNLAQAKSDQKVLGEELDGCNLKLMELDAAVQKFSEQNGQLGKPLAKKIGKLTELHQQTI RQAENRLSKLSQAASHLEEYNEMLEFILKWIEKAKVLVHGKITWNSANQLREQYVLHQTM LEESEEIHSNLEAMIVKLQYLASVYSTEKMSQQVAELGRESEELRQMIKIRMHNLQDAAK DMKKFETELKNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQIC QSALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLRE LIEGAHREIEDTPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHA TMLLTVTEVEGLAEGTEDLDRELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSE ISSPPACRSPSPVANADASVNQDIAYYQALSAERLQTDAARIHPSTLPSQEFYEPGLEPS ATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEH GRSPESQMAEHQSSSQALMDEILMLQDEISELQSSLAEELVSESPESDPAEQLALQSTLT VLAERMSTIKMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDT ALGTAKEPMDMEAQLVDCQNMLLEIEQKVVALSELSVHNDNLLLEGKAHTKEEAEQLAIK LRVLKGSLLELQRALHDKQLNIQQGTAQEKEESHVDLTASQSPGVQEWLAQARTTWTHQR QSSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETSGGAGEKPDVLSQELGMEGE KSAAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQTQD KSAVTSLLDGLNQVFEEVSSQSGGKKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATAL LPEETEACLFNQETLAKDIKEMSEEMDKNRNLFSQAFPENGDNRDVIEDTLGCLLGRLSL LDSVVNQRCHQMKERLQQILNFQNDLKVLCTSLADNKYIILQKLANVFEQPVAEQIEAIQ QAEDGLKELDAGIIELKRRGDKLQIEQPSMQELSKLQDMYDELMMTIGSRRSGLNQNLAL KSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETL FRKIISFAVPQETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDYQELSRQLEV VESSIPSVGLVEESEDRLIDRIALYQRLKSSLNEYQPKLYQVLDDGKRLLISISCSDLEG QLNQLGEHWLNNTNKVSKELHRLETVLKHWTRYQSESVELIHWLQSAKDRLEFWTQQSVT VPQELEMVRDHLNAFLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTAALRSELSHIDSQ WTDLLTNIPTVQEKLHQLQMDKLPSRHAISEVMTWISLMENVIQKDEENIQNSVGYKAIH EYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQ GLVTEKIQLLEGLLESWSEYENNVQSLKTWYETQENRLKQQHRIGDQASVQNAMKDCQDL EDLVKAKEKEVERIEQSGLALIQNKKEEVSGIVMSTLRELNQTWANLDHMVGQLKILLKS VFDQWNNHKVAFDEINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKNL QRFGSITNQLLKECHPPVTETLTNTLKDVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDY SQQCASTVQQQEDRTNELLKAATNKDIADDEAATWIQDCNDLLKGLGIVKDSLFVLHELG EQLKQQVDASAASAIQSDQLSLSQHLCTLEQALCKQQTTLQVGVLDYETFTKSLEALEAW IVEAEDILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEI KRMQNLNRRWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNY QHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFYLKLTLLSNQWQGV IRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPVSALGSVPIPLQQARTLFDEV QFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEIQEKWKSASVRLEEQKKK LAFLLKDWENCENGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENVAGSWTDD MAQLTLLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSE KNKELCEWLTQMESKVSQNGDILIEDMIEKLKKDYQEEIAVAQENKIQLQQMGERLARAS HESKASEIEYKLGKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESE LAKPIVYDSCDSDEIQKKLTEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECD SIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKISERTAAFPSS SGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQ RWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIK QLKAFQQEISLNHNKIEHIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYH KKLIRLPLPDDEHDLSDRELELDDSAALSDLHWRDTSADSVLSPQPSSNPSLSLVQPLRS ERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQDDKDFYLRGAVGLSDV MIPESPEAYVKLTESAIRNTSGPPSALESQIRQLDKALDESRFQMQQTENIIRSKTPTGP ELDSSYRGYMKLLGECSGSIDSVKRLEHKLREEEENFPGFVNLNSTETQTAGVIDRWELI QAQALSKELRMKQNLQKWQQFNSDLNNIWTWLGETEEELEQLQRLELSTDIQAIELQIKK LKELQKAVDHRKALILSINLCSSEFTQTDSEKSQDLQDRLSQMNGRWDHVCSLLEEWRGL LQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNQDAETLQDHHKQLMQIRHELLE SQLKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSS SQQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGS DSSLSEPRPAQSGRAFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSF HPMLRYTNGPPPL NT seq 26502 nt NT seq  +upstreamnt  +downstreamnt atggcagcttccaggacaacctcacggtctcctcgggacattgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccactggtggtagatgatctttttgaagacatgaaagatggt gttaagctgcttgcacttctggaggttctttctgggcagaaattgccttgtgaacaagga cgccgtatgaagcggatccatgctgttgctaatattggcacagcactcaagttccttgaa ggaaggaagtccatgtacagaggatcaccgattaaattagtcaacattaactccactgat atagctgatggccgaccatcaatagttcttggattgatgtggaccattattctatatttc cagattgaggagttgaccagcaacctgccacagctgcagtctctgtctggcagcacatcc tctgtggatagcatggttagtgctgagactgccagccccccaagtaaacggaaagtggcc accaagattcaaggaaatgctaagaaggctttattaaagtgggtccactacacagtagcc aagcagacgggaatagaagtaaaggactttgggcggagttggagaagtggggttgccttc cattctgtcatccatgccattcgaccagaactagtggacttggagaaagtgaaagggaga tctaaccgggaaaacctggaggaggctttcactattgctgaaacagaactaggaatcccc agactgttggatcctgaagatgttgatgtggataaaccagatgagaagtctattatgacc tatgtagcccaatttctgaagcattaccctgacatccacaatacaggcactgatgggcaa gaaaatgatgaaatacttccaggttttccatcttttgcaaattctatccaaaattttaag agagaagacaggctaattttgaaggaaacaaaagtttggatagaacaatttgaaagagat ttgacaagggcacagatgacagaatcaaatttgcaagataaatatcagtcatttaagcac ttcagagttcagtatgaaataaaaaggaaacagattgaacatttaatacaaccagtacat agagatggtaaactgtcacttgaccaagcattggtaaaacaatcctgggacagagtgtcc tccaggctctttgattggcatatacagcttgataaatctctccctgcacctctgggcact ataggtgcctggttatacagagcagaggtagctctgagggaggaaattaccattcagcag gtccatgaggaaacggccaacacaatacaacggaaacgtgagcaacacaaggatctgctt caaaacacagatgctcacaaaagagcattccatgagatctaccggaccaggtctgttaac gggatcccagtgccacctgaccaattagaggacatggcagaaaggtttcattttgtttcc tccacatcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctc tcactgctggttcttgcagagtcaaagctgaaatcttggatcatcaagtatgggaggaga gagtcagtggagctgcttctgcaaaactatatctcttttatagaaaataccaagttcttt gaacagtatgaagtgacataccagatcttaaaacagacagcggagatgtacatccaagct gatggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccactgcccag tggaggaacctctcagtggaagttaggagcgtgcggagcatgcttgaagaagtcatcgct aactgggatcgatatggcaatacggtggccagtcttcaggcctggctggaggatgctgag aaaatgctaaatcagacagagcacgctaaaaaggattttttccgaaatttgcctcactgg atacagcagcatgctgccatgaatgatgcaggcaattttctaattgaaacatgtgatgag atggtttcccgagaccttaaacagcagttgctattgctcaatggccgatggagggagttg ttcatggaagtcaagcaatatgctcgggctgatgagctggacagaatgaagaaggaatac acagactgtgtcactgccctgtctgattttgcaatgggagcccataagaaactttccgaa cccttagaagtctcttttcttaatgtcaagctattaattcaagacttggaggacattgag cagagggtacctgtaatggatgctcaatacaagatgattacaaagactgcacacctcatt accaaagagagttcccaagaagaagctaatgaaatgtttgcaaccatgtctgggctcaaa gaacagctaaccaaggtcaaggactgttactctccactcctttatgagtctcagcagctg ttgataccattggaagaattagaaaagcagatgacattcttttatgactcagttgggaaa atcaatgaaattttaacagttcttgagcatgaggcacaatctagtgctgtttttaaacag aaacaacaggaactgtcagcttgtcaagaaagctgtaagaaaaccatgacacaaattgag aaaggcagtcaaaatgttcaaaagttcatgaccttgagcagtgtgttaaagcattttgat cagacaaagctgcacagacagattgcagatgcccatggtgctttccagaatatgatgaag aaaattggagactggaagaaacatgtggaaaccaatagtcgtttgatgaagaaatttgag gagtctcgagcagagttggagaaggtgctgcggatagctcaggagggcttggaagaaaag ggaaatccagaagacctcctgaggagacataccgagttcttcagccagctggaccagaga gtgctcaatgctttcctaaaagcttgtgatgagctcaccgacattctccctgagcaggaa cagcagggcctacaggaagctgttagaaagctccacaaacagtggaaggatcttcaagga gaagccccatatcatttgcttcatctgaagattgatgtggagaagaatagattcttagct tctgtagaagaatgcaggactgagctggatcgagagaccaagctggtgccccaggaaggc agtgaaaagattattaaagagcacaggattttcttcagtgacaaaggtcctcatcatgtt tgtgagaaaaggttacagcttattgaagaactgtgtctgaagctcccaggccgggaccca gtaaggaacacacctgaaacctgtcacgtgactctcaaagagctcagagctgccattgat accacctatatgaagctcgtggaggacccagacaagtggaaggactatactagcagaatt tctcagttctcatcttggatatctgcaaaggagacagagttgaaagggtttaagaatgag cccatcgatactgccaaccatggaaaggttaaacatgctgtagaggagatcagaaatgat gttaccacaaagggcgagactctcaactggctgaaatccaggcttaaagttttaattgaa gtttcttctgagaatgaagcccaaaagcaaggagatgagctagcaaaattatctggttct ttcaaagctcttgtagctttattgtcagaggttgaaaagatgttaagcaactttggggac tgtgtccagtacaaagaaatagttaaaagctcccttgaggagttaatttctggctctaaa gaagtccaggaacaagctgagaagatcctggacactgaaaatctgtttgaagcacagcag ttacttcttcatcaccagcaaaagacaaagaggatttctgcaaagaagagagatgtgcag cagcagatacagcaggctcagcagggagaaggtgggctgccgggccaagtccgggaggag ctgcggaagctggagagcaccctggacaacatggagcacagcagggagaaacaggaacgc cgcatccaggtcacattaagaaagtgggagcgatttgaaacgaacaaagagacagtggtc agatacctttttcaaacaggttccagccatgagcgcttcctaagttatagcagtttggaa agtttatcttcagaattggaacagacaaaggagttttctaaacgaacagaaggtattgca gtccaggctgaaaatcttgtgaaggaagcttctgagataccacttgggcccaaaaataag cagctgcttcagcagcaggccaagtcaatcaaagagcaagtcaaaaaattagaagacaca cttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaat aattttgagaccctgtccatctggataactgagaaagaaaaagaactcaataccttggaa acttcgtcatctgccatggacatgcaaatcaaccagattaaggtcataattcaggaaata caaagcaagctcagcagtattacagagctagaagaatcagctcaatcttttgctcagttt 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cagcatttgttatctgagatggagtcactcaagccaaaggtccatgctgtgcagatttgc cagagtgcactgaggatccctgaagatgtggtcaccagcttgccactgtgccatgctgct ctgcatctgcaggaggaggccagccggttacagcacacagcaatccagcagtgcaacatc atgcaggaggctgtggtgcaatatgaacagtatgagcaagaaatgcagcacctccgggag cttatagaaggagcgcacagagaaatcgaggatacacctgtggccaccagtaacatccag gagctgcaagcccagatttctcggcatgaggagctggctcagaaaatcaagggctaccag gagcagatcgcctctttgaactccaagtgcaagatgctgacgatgaaagccaagcatgcc accatgctgctgacggtcacggaggtggaggggctggcggaggggacggaggacctggac agggagctcctccccgcgacctcggcccacccctctgtggtcatgatgactgcaggtcgt tgtcacactttgctgtcacctgtgacggaggagtctggggaggagggaaccaacagtgaa atttcctctccacctgcctgtcgctccccttcacctgtggctaatgcagatgcctctgtt aaccaggacattgcttattaccaagcactatctgctgagaggttacagactgatgccgca aggatccaccccagcacgttgccatctcaggagttctacgaaccaggactggagccatct gctactgctaaactggatgatttgcagcgttcttgggaaaccttaaagaatgtgataagt gaaaagcagcgcactctctatgaagctttggaacgccagcagaagtaccaggactcccta cagtccatctccacaaagatggaggccattgagatgaaactcagtgagagtctggagcat ggcaggagtccagaaagccagatggctgaacatcagtcttcttcacaggcactgatggat gagattctcatgcttcaagatgagatcagtgagctccagtcgtctctggcagaggagctg gtgtccgagtctcccgagtccgaccccgccgaacagctagccttgcagtccacactcact gtcttagccgagcggatgtccaccatcaagatgaaggcatcagggaagcgacagcttttg gaggagaagttaaatgatcagcttgaggaacagagacaggaacaggccctgcagaggtat cgctgtgaagccgatgagctggaccactggctcttgagcactaaagccactttggacaca gcactgggtacagcgaaggagcctatggacatggaagcccagctagtggactgccagaac atgctgttggaaatagagcagaaggtggtggccttatcagaactctcagtccacaatgac aacctgctgctggaaggcaaggctcacaccaaggaggaggctgagcagcttgccataaag ctgagagtgctcaaggggagcctcctggagctgcagagagccctgcacgacaaacagctc aacatccagcagggaacagcacaagagaaggaggagagccatgtggacctgactgccagc cagagccctggtgtccaggaatggctggcccaagcacggaccacgtggacccaccagaga cagagcagtctccagcaacaaaaagagttggaacaggaattagcagaacagaagagcctc ctgcggtcagtggccagtcgtggggaggaaattctcacccagcactcagctgcagagacc tctggtggtgctggcgaaaaacctgatgtgttatcccaggaattggggatggaaggggag aaatcagctgctgaagaccagatgagaatgaaatgggaaagcctacatcaagaatttagt accaagcagaagctactacagaatgttctggaacaggaacaagagcaagtgctatacagc aggccaaatcggctcctgtctggtgtgccactatacaaaggggatgggcagacccaagac aaatctgcagtgacatctttgctggatggattgaaccaggtcttcgaagaggtttcatca cagagtggggggaaaaagaggcagaacattcacttggaacagaagttatatgatggggtg tcagctacctccacatggttggatgatgttgaggaacgtttatttgttgccacagcactt ttaccagaagaaacagaagcttgcctcttcaaccaagagactcttgccaaagatattaag gaaatgtctgaagaaatggataagaacaggaacttgttttcccaagcatttccagagaat ggtgataaccgagatgtcattgaagacactttgggttgtcttttgggcaggttgtccttg ctagactcagtagtaaatcagcgctgtcatcagatgaaggaaagacttcagcaaatacta aatttccagaatgatctgaaggtgctgtgtacatcactggctgacaacaaatacatcatt ctacagaaactggcaaatgtgtttgaacaacctgtggcagagcaaatagaggcaatacaa caggctgaagatgggctaaaggaactggatgcaggaatcattgaattaaaaaggcgtggt gacaagttgcagattgagcagccttccatgcaggaactgtccaaacttcaggatatgtat gatgaactaatgatgaccataggctcccggcggagtggtctgaaccagaaccttgcactc aagagtcagtacgaaagggccctgcaagatctggctgacctgctcgagactggacaggag aagatggcaggtgaccagaaaatcattgtgtcttccaaagaggaaattcaacaactactt gacaaacataaggaatattttcagggcctggaatctcatatgatcttgactgaaacactc ttcagaaagataatcagctttgcagtcccacaggaaactcagttccacacagaactgatg gcacaggcttcagctgtactaaaacgggcccacaagaggggtgtggagttggagtacatt ctagagacatggtctcatctggatgaagactatcaggagctcagcagacagctggaggtg gtggaaagtagcatcccgagtgtggggttggtggaagaaagcgaggacaggctcatcgac cggattgcactttatcagcgcttgaaatccagccttaatgaataccagcccaaattatat caggtattagatgatgggaaacgactgcttatatccattagctgctcagatctagaaggc cagctaaatcaacttggagaacactggttaaataataccaacaaggtgtctaaggaactt cacagattggaaacagtattgaaacactggaccagatatcaaagcgaatctgtagaactt attcactggttgcaatctgcaaaagacaggctagaattttggactcaacaatctgtgaca gtcccacaagaactggaaatggtccgtgatcatctaaatgccttcctggagttttccaaa gaagtggatgccaaatcttctctgaaatcgtctgtcctcagcactggaaatcagcttctt cgattaaagaaagtagacacagctgccctacgttcagagctgtcacacattgacagccaa tggactgatctgctgacaaatattccaactgtacaggaaaagctccatcagctccaaatg gataagctgccttcccgtcatgccatttctgaagttatgacttggatttctcttatggaa aatgttattcaaaaggatgaagagaatatacaaaattcagtaggttacaaggcaattcat gaataccttcagaaatataagggttttaagatagatattaactgtaaacagttgacagtt gattttgtgaatcagtctgtgctacaaatcagtagtcaggatgtggaaagtaaacgcagt gataagactgattttgctgaacaacttggagccatgaataaaagttggcaaatcctgcag ggtctagtgactgagaagatccagctgttggaaggcttattggaatcttggtcagaatat gaaaataacgtacaaagtctgaaaacttggtatgaaacccaggaaaacagactaaagcaa cagcatcgaattggagatcaggcttcagttcagaacgcaatgaaagactgtcaggatcta gaagatttggttaaagcaaaagaaaaagaggtagagagaattgagcagagtggacttgct ttgattcagaacaagaaagaagaagtctctggcattgtcatgagcacgctgcgggagctg aaccaaacctgggcaaatttagaccacatggttgggcaattaaagatactgttgaagtcc gtgtttgaccaatggaacaatcacaaggtggcctttgatgagataaacagctacctcatg gaggccagatattctctttcccgcttccgtctgctgactggctctttagaagctgtacaa gttcaggtagacaatcttcagaatcttcaagatgatctggaaaaacaggaaaagaaccta cagaggtttggctctatcaccaaccaactgttaaaagagtgtcacccacctgtgacagaa actcttaccaatacattaaaagatgtcaatatgagatggaataatttgctggaagagatt gctgagcagctgcactccagcaaagccctacttcaactctggcaaagatacaaggactac tcccaacagtgtgcttctacagttcagcagcaagaggaccgaaccaatgagctcttgaag gcagccactaacaaggacattgctgatgacgaagctgctacatggattcaagattgcaat gatctcctcaaaggactggggatagtgaaggattccctttttgttctccatgagctggga gagcagctcaagcaacaagtggatgcttcagcagcatcagccattcaatctgatcagctg tctttgagtcaacacctatgtaccctagaacaggctctttgcaagcagcagactacatta caggttggagttcttgactatgagacctttaccaagagtttagaagcattggaggcctgg atagtagaagctgaagacatattacaagggcaggaccctagccactcatctgacctctca accattcaggaaaggatggaagaacttaagggacagatgttaaaattcagcagtatggcc cctgatctagaccgcctaaatgagcttgggtataggctaccactgaatgataaagaaatc aaaaggatgcagaatctgaaccggcgctggtctctgatctcctctcagaccacagaaaga ttcagtaagttgcaatcatttttgctacaacatcagactttcttggaaaaatgtgaaaca tggatggaattcctggttcaaacggaacaaaaattagcagtagagatttcaggcaattat cagcatcttttggagcagcagagagcacatgagttgtttcaagcagagatgtttagtcgt cagcagattttgcactcaatcattattgatggtcagcgtcttctagaacaaggtcaagtt gatgacagggatgaattctacctgaaattgacacttctcagcaatcagtggcagggagtg attcgccgggcccagcagaggaggggcatcattgacagccagattcgccagtggcagcgg tacagggagatggcagagaagcttcgtaaatggttggttgaagtgtcctatcttcccgtg agtgctctcggaagtgtcccaataccactgcaacaggcaaggaccctctttgatgaagtg cagttcaaagaaaaagtgttcctgcgacagcaaggcagctacatcctaacagtggaggct ggcaagcagctcctgctctcagcggacagtggggctgaggctgccttgcaagcagaactc actgaaatccaagagaagtggaaatcagccagcgtgcgtttggaggaacagaagaaaaaa ctggccttcttgttgaaagactgggaaaactgtgagaacggaatagctgattctctggag aaactacgaactttcaaaaagaagctttctcagtctcttccagatcaccatgaggagctg catgcagagcaaatgcgttgcaaggagctggaaaatgtagctgggagctggacagatgat atggctcagctgacactgctgaaggatactctctgtgcctacatcagcgccgatgatatc tccatcctgaatgaacgcatggagcttctgcaaaggcagtgggaagaactgtgccaccag ctctccttaaggcggcagcaagtaagtgaaagattgaatgaatgggcagtcttcagtgaa aagaacaaggagctttgtgaatggttgacccagatggaaagcaaagtttctcaaaatgga gacatcctcattgaagatatgatagaaaagctcaagaaggattatcaagaggaaattgct gttgcccaagagaacaaaatacagctccagcaaatgggagaacgacttgctagagccagc catgaaagcaaagcctctgagattgaatacaaactcggaaaggttaatgaccggtggcag catctcctggatctcatggcagccagggtaaagaagctgaaggagaccctggttgccgta cagcagctggataagaacatgagcagcctgaggacgtggctggctcacatcgagtcagag ctggccaagcccatagtctatgattcctgtgactcggatgaaatacagaaaaagcttact gagcagcaggagcttcagagagacattgagaaacatagcacaggcgtggcctctgttctc aacttatgtgaggtcctgcttcatgactgtgatgcctgcgccacggatgcagagtgtgat tccatccagcaggcgacgcgaaacctggaccggcgatggagaaatatctgtgccatgtcc atggaaagaaggctcaaaattgaagagacatggcgattgtggcagaagtttctcgatgat tattctcgttttgaagattggctcaagatttcagaaaggacagctgccttccccagctct tctggggtgctctatacagttgccaaggaagaactaaagaaatttgaggctttccagcga caggtccacgagagcctgacccagctagaactaatcaacaagcagtaccgtcgcctggcc agagagaaccgcaccgattctgcttgtagcctaaagcagatggttcatgaaggcaaccag agatgggacaacctgcaaaagcgtgtcacctccatcttgcgcagactcaagcatttcatt ggccagcgtgaggagtttgagactgcacgggacagcattctggtgtggctgacagagatg gatctacagctcactaatattgagcatttttctgagtgtgatgttcaagctaaaataaag caactcaaggccttccagcaagaaatttcactgaaccacaataagattgagcacataatt gcccaaggagaacagcttatagaaaagagtgagcccttggatgcggcagtcattgaggaa gagctagatgaactccggcgttactgtcaggaagtctttgggcgtgtggaaagataccat aagaaactgattcgcctgcctctcccagatgatgagcatgacctctctgaccgggagctg gagctggatgactctgcagctctctcagacctccactggcgtgacacctctgcagacagc gtgctctctccccagccttcctccaacccctccctctcactcgtccagcccctgcggagt gagcggtcaggacgagacacgcctgccagtgtggactccatccccctggagtgggaccat gactatgacctcagtcgtgacctggagtctgctgtgtctagaactctaccctctgaggat gaagagggtcaggatgataaagatttctacctcaggggagctgttggcttatcagatgta atgatccccgaaagtcccgaggcctatgtaaaactcacagaaagtgcaatcagaaatacc tctggacctcccagtgccttagagtcacagatccgacaactggacaaagcattggatgag agccgttttcagatgcaacaaactgaaaatattatccgcagcaaaactccgacaggaccg gagctagattccagctatagaggctatatgaaattgctgggtgagtgcagcggcagtata gactcagtgaagagactggaacacaaactaagggaggaagaagagaattttccaggcttc gttaacctgaatagtacggaaacccaaacagctggtgtgattgaccgatgggaactcatc caagcacaggcccttagcaaggagctgagaatgaaacagaacctccagaagtggcagcag ttcaactcggacctgaacaacatctggacctggctgggggagacagaggaagagttggaa cagctgcagcgcctagagcttagcactgacatccaggctatcgagctccagataaaaaag ctcaaggagctccagaaagctgtggaccaccgcaaagccctcatcctctccatcaacctg tgcagctctgagttcacccagactgacagtgaaaaaagccaagatctgcaagatcgccta tcccagatgaacgggcgctgggaccatgtgtgctcattgctagaagagtggcggggcctg ctccaagatgcactgatgcagtgtcaggatttccatgaaatgagtcatggtttgctgctt atgctggagaacatcgacagaaggaaaaatgaaattgtccctattgattctaaccaggat gcagagacacttcaggaccatcacaaacagcttatgcaaataaggcatgagctgttggaa tcccagctcaaagtggcctcactgcaagacatgtcttgccaactcttggtgaatgctgaa ggcacagattgtttagaagccaaagaaaaagtccatgtgattggaaatcggctcaaactt ctcttgaaggaggtcagtcgtcacatcaaggagctggagaagttattagatatgtcaagc agtcagcaggatttgtcttcctggtcttctgctgatgaactggacacctcaggatctgtg agtcctacatcaggaagaagcaccccaaacagacaaagaacgccacgaggcaaatgtagt ctctcacagcctggaccctctgtcaacagtccacatagcaggtccataaaaggtggctcc gattcctccctttctgagcctcggccagctcagtccggccgagccttcctattcagagtc ctccgagcggctcttccacttcagcttctcctgctgctcctcatcgggctcgcctgcctt gtaccaatgtcagaggaagactatagttgtgccctctccaacaactttgcccgatcattc caccccatgctcagatacacaaatggccctcctccgctctga

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