KEGG   Vulpes lagopus (Arctic fox): 121488903
Entry
121488903         CDS       T07435                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg01521  EGFR tyrosine kinase inhibitor resistance
vlg01522  Endocrine resistance
vlg01524  Platinum drug resistance
vlg04010  MAPK signaling pathway
vlg04012  ErbB signaling pathway
vlg04014  Ras signaling pathway
vlg04015  Rap1 signaling pathway
vlg04022  cGMP-PKG signaling pathway
vlg04024  cAMP signaling pathway
vlg04062  Chemokine signaling pathway
vlg04066  HIF-1 signaling pathway
vlg04068  FoxO signaling pathway
vlg04071  Sphingolipid signaling pathway
vlg04072  Phospholipase D signaling pathway
vlg04140  Autophagy - animal
vlg04150  mTOR signaling pathway
vlg04151  PI3K-Akt signaling pathway
vlg04152  AMPK signaling pathway
vlg04210  Apoptosis
vlg04211  Longevity regulating pathway
vlg04213  Longevity regulating pathway - multiple species
vlg04218  Cellular senescence
vlg04261  Adrenergic signaling in cardiomyocytes
vlg04370  VEGF signaling pathway
vlg04371  Apelin signaling pathway
vlg04380  Osteoclast differentiation
vlg04510  Focal adhesion
vlg04517  IgSF CAM signaling
vlg04518  Integrin signaling
vlg04550  Signaling pathways regulating pluripotency of stem cells
vlg04611  Platelet activation
vlg04613  Neutrophil extracellular trap formation
vlg04620  Toll-like receptor signaling pathway
vlg04625  C-type lectin receptor signaling pathway
vlg04630  JAK-STAT signaling pathway
vlg04660  T cell receptor signaling pathway
vlg04662  B cell receptor signaling pathway
vlg04664  Fc epsilon RI signaling pathway
vlg04666  Fc gamma R-mediated phagocytosis
vlg04668  TNF signaling pathway
vlg04722  Neurotrophin signaling pathway
vlg04725  Cholinergic synapse
vlg04728  Dopaminergic synapse
vlg04810  Regulation of actin cytoskeleton
vlg04910  Insulin signaling pathway
vlg04914  Progesterone-mediated oocyte maturation
vlg04915  Estrogen signaling pathway
vlg04917  Prolactin signaling pathway
vlg04919  Thyroid hormone signaling pathway
vlg04920  Adipocytokine signaling pathway
vlg04922  Glucagon signaling pathway
vlg04923  Regulation of lipolysis in adipocytes
vlg04926  Relaxin signaling pathway
vlg04929  GnRH secretion
vlg04931  Insulin resistance
vlg04932  Non-alcoholic fatty liver disease
vlg04933  AGE-RAGE signaling pathway in diabetic complications
vlg04935  Growth hormone synthesis, secretion and action
vlg04936  Alcoholic liver disease
vlg04973  Carbohydrate digestion and absorption
vlg05010  Alzheimer disease
vlg05017  Spinocerebellar ataxia
vlg05132  Salmonella infection
vlg05135  Yersinia infection
vlg05142  Chagas disease
vlg05145  Toxoplasmosis
vlg05152  Tuberculosis
vlg05160  Hepatitis C
vlg05161  Hepatitis B
vlg05162  Measles
vlg05163  Human cytomegalovirus infection
vlg05164  Influenza A
vlg05165  Human papillomavirus infection
vlg05166  Human T-cell leukemia virus 1 infection
vlg05167  Kaposi sarcoma-associated herpesvirus infection
vlg05168  Herpes simplex virus 1 infection
vlg05169  Epstein-Barr virus infection
vlg05170  Human immunodeficiency virus 1 infection
vlg05200  Pathways in cancer
vlg05205  Proteoglycans in cancer
vlg05207  Chemical carcinogenesis - receptor activation
vlg05208  Chemical carcinogenesis - reactive oxygen species
vlg05210  Colorectal cancer
vlg05211  Renal cell carcinoma
vlg05212  Pancreatic cancer
vlg05213  Endometrial cancer
vlg05214  Glioma
vlg05215  Prostate cancer
vlg05218  Melanoma
vlg05220  Chronic myeloid leukemia
vlg05221  Acute myeloid leukemia
vlg05222  Small cell lung cancer
vlg05223  Non-small cell lung cancer
vlg05224  Breast cancer
vlg05225  Hepatocellular carcinoma
vlg05226  Gastric cancer
vlg05230  Central carbon metabolism in cancer
vlg05231  Choline metabolism in cancer
vlg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
vlg05415  Diabetic cardiomyopathy
vlg05417  Lipid and atherosclerosis
vlg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121488903 (AKT3)
   04012 ErbB signaling pathway
    121488903 (AKT3)
   04014 Ras signaling pathway
    121488903 (AKT3)
   04015 Rap1 signaling pathway
    121488903 (AKT3)
   04370 VEGF signaling pathway
    121488903 (AKT3)
   04371 Apelin signaling pathway
    121488903 (AKT3)
   04630 JAK-STAT signaling pathway
    121488903 (AKT3)
   04668 TNF signaling pathway
    121488903 (AKT3)
   04066 HIF-1 signaling pathway
    121488903 (AKT3)
   04068 FoxO signaling pathway
    121488903 (AKT3)
   04072 Phospholipase D signaling pathway
    121488903 (AKT3)
   04071 Sphingolipid signaling pathway
    121488903 (AKT3)
   04024 cAMP signaling pathway
    121488903 (AKT3)
   04022 cGMP-PKG signaling pathway
    121488903 (AKT3)
   04151 PI3K-Akt signaling pathway
    121488903 (AKT3)
   04152 AMPK signaling pathway
    121488903 (AKT3)
   04150 mTOR signaling pathway
    121488903 (AKT3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    121488903 (AKT3)
   04518 Integrin signaling
    121488903 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121488903 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    121488903 (AKT3)
   04218 Cellular senescence
    121488903 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121488903 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    121488903 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    121488903 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121488903 (AKT3)
   04613 Neutrophil extracellular trap formation
    121488903 (AKT3)
   04620 Toll-like receptor signaling pathway
    121488903 (AKT3)
   04625 C-type lectin receptor signaling pathway
    121488903 (AKT3)
   04660 T cell receptor signaling pathway
    121488903 (AKT3)
   04662 B cell receptor signaling pathway
    121488903 (AKT3)
   04664 Fc epsilon RI signaling pathway
    121488903 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    121488903 (AKT3)
   04062 Chemokine signaling pathway
    121488903 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    121488903 (AKT3)
   04922 Glucagon signaling pathway
    121488903 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    121488903 (AKT3)
   04920 Adipocytokine signaling pathway
    121488903 (AKT3)
   04929 GnRH secretion
    121488903 (AKT3)
   04915 Estrogen signaling pathway
    121488903 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    121488903 (AKT3)
   04917 Prolactin signaling pathway
    121488903 (AKT3)
   04926 Relaxin signaling pathway
    121488903 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    121488903 (AKT3)
   04919 Thyroid hormone signaling pathway
    121488903 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121488903 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    121488903 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    121488903 (AKT3)
   04728 Dopaminergic synapse
    121488903 (AKT3)
   04722 Neurotrophin signaling pathway
    121488903 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121488903 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    121488903 (AKT3)
   04213 Longevity regulating pathway - multiple species
    121488903 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121488903 (AKT3)
   05205 Proteoglycans in cancer
    121488903 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    121488903 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    121488903 (AKT3)
   05230 Central carbon metabolism in cancer
    121488903 (AKT3)
   05231 Choline metabolism in cancer
    121488903 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121488903 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121488903 (AKT3)
   05212 Pancreatic cancer
    121488903 (AKT3)
   05225 Hepatocellular carcinoma
    121488903 (AKT3)
   05226 Gastric cancer
    121488903 (AKT3)
   05214 Glioma
    121488903 (AKT3)
   05221 Acute myeloid leukemia
    121488903 (AKT3)
   05220 Chronic myeloid leukemia
    121488903 (AKT3)
   05218 Melanoma
    121488903 (AKT3)
   05211 Renal cell carcinoma
    121488903 (AKT3)
   05215 Prostate cancer
    121488903 (AKT3)
   05213 Endometrial cancer
    121488903 (AKT3)
   05224 Breast cancer
    121488903 (AKT3)
   05222 Small cell lung cancer
    121488903 (AKT3)
   05223 Non-small cell lung cancer
    121488903 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121488903 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    121488903 (AKT3)
   05161 Hepatitis B
    121488903 (AKT3)
   05160 Hepatitis C
    121488903 (AKT3)
   05164 Influenza A
    121488903 (AKT3)
   05162 Measles
    121488903 (AKT3)
   05168 Herpes simplex virus 1 infection
    121488903 (AKT3)
   05163 Human cytomegalovirus infection
    121488903 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121488903 (AKT3)
   05169 Epstein-Barr virus infection
    121488903 (AKT3)
   05165 Human papillomavirus infection
    121488903 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    121488903 (AKT3)
   05135 Yersinia infection
    121488903 (AKT3)
   05152 Tuberculosis
    121488903 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    121488903 (AKT3)
   05142 Chagas disease
    121488903 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121488903 (AKT3)
   05017 Spinocerebellar ataxia
    121488903 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121488903 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    121488903 (AKT3)
   05415 Diabetic cardiomyopathy
    121488903 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    121488903 (AKT3)
   04932 Non-alcoholic fatty liver disease
    121488903 (AKT3)
   04931 Insulin resistance
    121488903 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    121488903 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121488903 (AKT3)
   01524 Platinum drug resistance
    121488903 (AKT3)
   01522 Endocrine resistance
    121488903 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vlg01001]
    121488903 (AKT3)
Enzymes [BR:vlg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     121488903 (AKT3)
Protein kinases [BR:vlg01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   121488903 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1
Other DBs
NCBI-GeneID: 121488903
NCBI-ProteinID: XP_041607144
LinkDB
Position
1:151262999..151576969
AA seq 479 aa
MSDVTVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCVDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccgttgtgaaagaaggctgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagagtggacagaa
gctattcaggcggtagcagacagacttcagagacaagaagaagagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttccacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtgggaaatactatgctatgaagattctgaag
aaagaagtgattattgcaaaggatgaagtggcacatactctaacggaaagcagagtgtta
aagaacactcgacacccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctccgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggattacagatgca
gccaccatgaagacattctgtggcacaccagagtatctggcaccagaggtgttagaagac
aatgactatggccgagccgtggattggtggggactgggggtcgtcatgtatgaaatgatg
tgtgggaggttacctttctacaatcaggatcatgagaagctttttgaactaatactaatg
gaagacattaaattccctcgaacactctcttcagatgcaaaatcattgctttcggggctc
ttgataaaggatccaaataaacgccttggcgggggcccagatgatgcaaaagaaattatg
aggcacagtttcttctctggagtcaactggcaagatgtatacgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagataccagatatttcgatgaagaatttaca
gcgcagactattacaataacaccacctgaaaagtatgacgaggacggtatggactgcgtg
gacaacgagcggcggccgcacttccctcagttctcctactccgccagcggccgggagtaa

DBGET integrated database retrieval system